Faculty profile

Lena Palaniyappan

ResearcherPsychiatryMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Lena Palaniyappan

Researcher

Psychiatry

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
150 publications in the last five years, latest in 2026.
Senior (last) author on 76 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (5 CIHR), most recently in 2026.
Supervised 5 trainees who won CIHR awards, most recently in 2026.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

150

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Psychosis Schizophrenia Antipsychotics Digital Health Early Intervention Predictive Analysis Recovery Relapse

Latest papers

Putative glymphatic dysfunction links extracellular fluid dysregulation to white matter degeneration and clinical impairment in amyotrophic lateral sclerosis.
BMC medicine · 2026
Double DANTE-PRESS: Development of a 1H-MRS Multifrequency-Selective Sequence for Simultaneous In Vivo Quantification of Glutathione and Glutamate at 7 Tesla.
NMR in biomedicine · 2026
Resting magnetoencephalography alterations in severe mental illnesses: A systematic review.
Neuroscience and biobehavioral reviews · 2026 · senior author

All 150 publications

Latest funding

Youth Cannabis Outcomes and Neurodevelopmental and Clinical Trajectories (Y-CONECT)
CIHR · 2026 · Principal investigator
$2,396,391
Developing a novel tool to measure communication difficulties in SSD
CIHR · 2026 · Supervisor
$6,000
Peering through the layers: Unraveling mechanisms of predictive coding dysfunction in psychosis using depth-dependent ultra-high field MRI
CIHR · 2025 · Principal investigator
$100,000

All 15 grants and awards

150 publications.

Putative glymphatic dysfunction links extracellular fluid dysregulation to white matter degeneration and clinical impairment in amyotrophic lateral sclerosis.

Jin X, Fu Y, Qiu T, Li J, Zhang H, Chen Y, Chen K, Zhang Y, Wang J, Yi X, Palaniyappan L, Braden BB

BMC medicine2026

DOI: 10.1186/s12916-026-04948-z PMID: 42204548

Double DANTE-PRESS: Development of a 1H-MRS Multifrequency-Selective Sequence for Simultaneous In Vivo Quantification of Glutathione and Glutamate at 7 Tesla.

Kanagasabai K, Oran O, Palaniyappan L, Théberge J

NMR in biomedicine2026

DOI: 10.1002/nbm.70385 PMID: 42669963

Resting magnetoencephalography alterations in severe mental illnesses: A systematic review.

Gonzales-Aste F, Ahrens J, Boutet D, Wei HT, Baillet S, Palaniyappan L

Neuroscience and biobehavioral reviews2026Senior author

DOI: 10.1016/j.neubiorev.2026.106867 PMID: 42471042

Early intervention with clozapine: Is there a neurobiological critical period for treatment-resistant schizophrenia?

Krishnadas R, Leong IL, Fraczek J, Fernandez-Egea E, Palaniyappan L

Journal of psychopharmacology (Oxford, England)2026Senior author

DOI: 10.1177/02698811261488465 PMID: 42788527

Communication Context Matters: Elicitation Task Shapes the Clinical Utility of Speech Markers in Psychosis.

El Mouslih C, Mackinley M, Dzialoszynski P, Lodhi R, Richard J, Titone D, Palaniyappan L

Neuropsychologia2026Senior author

DOI: 10.1016/j.neuropsychologia.2026.109587 PMID: 42772404

Renaming vs. resolving: A reply to Baylé on discordance and disorganization.

Palaniyappan L, Sreeraj VS, Venkatasubramanian G, Voppel A, Sangiorgi A

Schizophrenia research2026First author

DOI: 10.1016/j.schres.2026.08.025 PMID: 42691597

Neurometabolites and Antipsychotic Response in Psychosis: A Mega-Analysis.

King B, Bojesen KB, Crisp C, de Bartolomeis A, de Haan L, de la Fuente-Sandoval C, Dempster K, Drake RJ, Dazzan P, Ebdrup BH, Fan L, Graff-Guerrero A, Glenthøj BY, Honda S, Howes O, Huang LC, Kahn R, MacCabe J, Matrone M, Merritt K, McIlwain M, McGuire P, Nakajima S, Lawrie SM, Palaniyappan L, Reyes-Madrigal F, Russell B, Sawa A, Shergill S, Singh KD, Sommer IE, Stone JM, Sun J, Tsugawa S, Ueno F, van der Pluijm M, van de Giessen E, Walters JTR, Yang K, Yang YK, Kempton MJ, Egerton A

JAMA psychiatry2026

DOI: 10.1001/jamapsychiatry.2026.1674 PMID: 42340705

Writing when writhing with psychosis: a computational linguistic autopsy of Vaslav Nijinsky's diary.

Palaniyappan L, Melshin G, Delgaram-Nejad O, Elleuch D, Voppel A

Medical humanities2026First author

DOI: 10.1136/medhum-2026-014121 PMID: 42629181

Social functioning and formal thought disorder in schizophrenia: A Bayesian meta-analysis.

Soldovieri CBC, Elleuch D, Ahrens J, Bambini V, Delgaram-Nejad O, Garani R, Harrison NA, Kircher T, Kuperberg G, Rossell SL, Sommer IE, Bosia M, Palaniyappan L

Schizophrenia research2026Senior author

DOI: 10.1016/j.schres.2026.07.028 PMID: 42566855

Longitudinal inference of hippocampal volume and morphometric hippocampal-cortical covariance in psychosis.

Totzek JF, Heckers S, Palaniyappan L, Young AL, Shah JL, Joober R, Malla A, Chakravarty MM, Lavigne KM, Lepage M

Cortex; a journal devoted to the study of the nervous system and behavior2026

DOI: 10.1016/j.cortex.2026.07.007 PMID: 42641351

Youth Cannabis Outcomes and Neurodevelopmental and Clinical Trajectories (Y-CONECT)

Principal investigatorCIHR2026TG:The CND Cannabis/Brain Health Cons-Parallel pre-clinical cannabis studies

Principal investigators: Rabin, Rachel A; Khokhar, Jibran Y; Palaniyappan, Lena K

Keywords: Brain Health; Cannabis; Cannabis Abstinence; Data Harmonization; Development; Mental Health; Neuroimaging; Parallel Preclinical Models; Psychopathology; Youth And Adolescence

$2,396,391

Developing a novel tool to measure communication difficulties in SSD

SupervisorCIHR2026Undergraduate Student Research Awards (USRA)

Principal investigators: Yemane, Millen Bahlbi

Keywords: Language Impairments; Schizophrenia Spectrum Disorders; Social Interaction

$6,000

Peering through the layers: Unraveling mechanisms of predictive coding dysfunction in psychosis using depth-dependent ultra-high field MRI

Principal investigatorCIHR2025Project Grant - Priority Announcement: Patient-Oriented Research

Principal investigators: Lavigne, Katie M; Palaniyappan, Lena K

Keywords: Cortical Layers; Delusions; Depth-Dependent Mri; Hallucinations; Prediction Error; Predictive Coding; Psychosis; Schizophrenia; Task-Based Neuroimaging; Ultra-High Field Mri

$100,000

Causal Dynamic Digital Markers for Precision Psychiatry: Integrating digital and computational phenotyping in precision psychiatry

SupervisorCIHR2025Canada Postdoctoral Research Award (CPRA) program

Principal investigators: Constant Pruvost, Axel

Keywords: Computational Phenotyping; Computational Psychiatry; Digital Markers; Digital Phenotyping; Markov Models; Precision Psychiatry; Psycholinguistic; Schizophrenia Spectrum Disorder; Speech Disturbances; Theoretical Neuroscience

$140,000

Beta Oscillations and the Neural Basis of Thought Disorder in Schizophrenia

SupervisorCIHR2025Canada Postdoctoral Research Award (CPRA) program

Principal investigators: Wei, Hsi

Keywords: Electrophysiology; Language Comprehe; Language Disorganization And Impoverishment; Language Production; Magnetoencephalography (Meg); Multi-Sensory Integration; Natural Language Processing; Neural Oscillations; Schizophrenia; Thought Disorder

$140,000

SNT-PSY: Stanford Neuromodulation Therapy in Psychosis

Principal investigatorCIHR2025Project Grant - PA: Patient-Oriented Research - General iCT

Principal investigators: Benrimoh, David A; Palaniyappan, Lena K

Keywords: Psychosis; Repetitive Transcranial Magnetic Stimulation; Rtms Treatment

$200,000

From Molecular Markers to Neural Oscillations: Bridging Dopamine and Brain Rhythms in Schizophrenia

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Ahrens, Jessica

Keywords: Dopamine; Neural Oscillations; Neuroimaging; Psychosis; Schizophrenia

$120,000

Predicting Psychotic Relapse using Speech-based Early-detection

Nominated PICIHR2024Project Grant

Principal investigators: Palaniyappan, Lena K; Achim, Amélie M

Keywords: Antipsychotics; Digital Health; Early Intervention; Natural Language Processing; Predictive Analysis; Psychosis; Recovery; Relapse; Schizophrenia; Speech

$1,201,050

Youth-emerging mental disorders: comprehensive analysis of long-term health, mortality, and socioeconomic outcomes across 4 Canadian provinces

Co-investigatorCIHR2024Project Grant

Principal investigators: Orri, Massimiliano; Anderson, Kelly K; de Oliveira, Claire; Gadermann, Anne M; Wang, JianLi

Keywords: Healthcare Utilization; Linked Administrative Data; Mortality; Service Use; Socioeconomic Outcomes; Suicide; Youth-Emerging Mental Disorders

$868,276

Building a clinical and genetic taxonomy of schizophrenia

SupervisorCIHR2023CIHR Fellowship

Principal investigators: Park, Min Tae M

Keywords: Genetics; Neuroimaging; Schizophrenia

$110,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Lena Palaniyappan

Research

Latest papers

Latest funding

Putative glymphatic dysfunction links extracellular fluid dysregulation to white matter degeneration and clinical impairment in amyotrophic lateral sclerosis.

Double DANTE-PRESS: Development of a 1H-MRS Multifrequency-Selective Sequence for Simultaneous In&#xa0;Vivo Quantification of Glutathione and Glutamate at 7&#x2009;Tesla.

Resting magnetoencephalography alterations in severe mental illnesses: A systematic review.

Early intervention with clozapine: Is there a neurobiological critical period for treatment-resistant schizophrenia?

Communication Context Matters: Elicitation Task Shapes the Clinical Utility of Speech Markers in Psychosis.

Renaming vs. resolving: A reply to Bayl&#xe9; on discordance and disorganization.

Neurometabolites and Antipsychotic Response in Psychosis: A Mega-Analysis.

Writing when writhing with psychosis: a computational linguistic autopsy of Vaslav Nijinsky's diary.

Social functioning and formal thought disorder in schizophrenia: A Bayesian meta-analysis.

Longitudinal inference of hippocampal volume and morphometric hippocampal-cortical covariance in psychosis.

Frequent collaborators

Lena Palaniyappan

Lena Palaniyappan

Suzanne Archie

Ridha Joober

Martin Lepage

Jordan Edwards

Ridha Joober

Julie Richard

Kara Dempster

Ashok Malla

Jai Shah

Martin Lepage

David Benrimoh

Jai Shah

Tara Elton-Marshall

Vincent Paquin

Richard Booth

Jean Theberge

Priya Subramanian

Ariel Graff-Guerrero

Jason Gilliland

Sylvain Baillet

Chiachen Cheng

Tara Elton-Marshall

Aristotle Voineskos

Roumen Milev

Rudolf Uher

Barbara Pavlova

Lisa McMurray

Hooman Ganjavi

Rachel Rabin

Double DANTE-PRESS: Development of a 1H-MRS Multifrequency-Selective Sequence for Simultaneous In Vivo Quantification of Glutathione and Glutamate at 7 Tesla.

Renaming vs. resolving: A reply to Baylé on discordance and disorganization.