Faculty profile

Lena Palaniyappan

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Professor, Psychiatrist, Medical Director of PEPPDepartment of PsychiatryWestern University

Lena Palaniyappan

Professor, Psychiatrist, Medical Director of PEPP

Department of Psychiatry

Schulich School of Medicine & Dentistry

Western University

London, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
144 publications in the last five years, latest in 2026.
Senior (last) author on 73 recent papers, a sign of leading a research group.
Principal investigator on 3 research grants (3 CIHR), most recently in 2018.
Supervisor on 2 trainee awards (2 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

233

Publications

258

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their Western University profile.

Neuroimaging Schizophrenia Connectivity Psychosis Ultra-High Field Mri Brain Stimulation Machine Learning Magnetic Resonance Spectroscopy

Latest papers

“I felt like that was a safe place to go”: a qualitative study of help-seeking experiences for early psychosis in primary care
Journal of Mental Health · 2026
Longitudinal inference of hippocampal volume and morphometric hippocampal-cortical covariance in psychosis.
Cortex; a journal devoted to the study of the nervous system and behavior · 2026
Speech and Language Markers of Bipolar Disorder: Challenges and Opportunities.
Bipolar disorders · 2026 · senior author

All 233 publications

Latest funding

Language impoverishment in schizophrenia: neural networks and intervention
CIHR · 2024 · Supervisor
$120,000
Schizophrenia and Cortical Association Fibres: A connectomic study
CIHR · 2021 · Supervisor
$105,000
The Impact of Cannabis Legalization and Availability on Incidence, Prevalence, and Health Services Utilization for Psychotic Disorders: Population-Based Evidence to Inform Policy Initiatives
CIHR · 2020 · Co-investigator

All 7 grants and awards

From the 150 most recent of 233 publications.

“I felt like that was a safe place to go”: a qualitative study of help-seeking experiences for early psychosis in primary care

Rodrigues R, Madakadze C, Edwards J, Booth R, Archie S, Palaniyappan L, Chan S, Nagy K, Anderson KK, co-investigators OBOTP

Journal of Mental Health20262 citations

DOI: 10.1080/09638237.2025.2595617

Longitudinal inference of hippocampal volume and morphometric hippocampal-cortical covariance in psychosis.

Totzek JF, Heckers S, Palaniyappan L, Young AL, Shah JL, Joober R, Malla A, Chakravarty MM, Lavigne KM, Lepage M

Cortex; a journal devoted to the study of the nervous system and behavior2026

DOI: 10.1016/j.cortex.2026.07.007 PMID: 42641351

Speech and Language Markers of Bipolar Disorder: Challenges and Opportunities.

Zaher F, Ahrens J, Raucher-Chéné D, Voppel A, Palaniyappan L

Bipolar disorders2026Senior author

DOI: 10.1111/bdi.70119 PMID: 42360412

Reading between the lines: Combining pause dynamics and semantic coherence for automated assessment of thought disorder.

Chen F, Xu W, Li C, Pakhomov S, Cohen A, Bhola S, Yin S, Tang SX, Mackinley M, Palaniyappan L, Ben-Zeev D, Cohen T

Neuropsychologia2026

DOI: 10.1016/j.neuropsychologia.2026.109473 PMID: 42061696

Structural brain complexity is associated with linguistic complexity in psychosis.

Korda A, Hinzen W, He R, van Dyken P, Mackinley M, Toyota E, Avram M, Andreou C, Borgwardt S, Palaniyappan L

European psychiatry : the journal of the Association of European Psychiatrists2026Senior author

DOI: 10.1192/j.eurpsy.2026.12242 PMID: 42476975

Age of Onset, Brain Controllability, and Working Memory Performance in First-Episode Schizophrenia.

Wang F, Liu Z, Yang J, Cheng P, Tan W, Huang D, Liu X, Zhong M, Yang J, Palaniyappan L

Schizophrenia bulletin2026Senior author

DOI: 10.1093/schbul/sbaf156 PMID: 40974052

Putative glymphatic function and free water in schizophrenia: A 7T DTI study across psychosis stages.

Qi G, Zhang Y, Wang YL, Anjum F, Theberge J, Jiang Y, Khan A, Palaniyappan L

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026Senior author

DOI: 10.1038/s41386-026-02391-5 PMID: 41876826

Renaming vs. resolving: A reply to Baylé on discordance and disorganization.

Palaniyappan L, Sreeraj VS, Venkatasubramanian G, Voppel A, Sangiorgi A

Schizophrenia research2026First author

DOI: 10.1016/j.schres.2026.08.025 PMID: 42691597

Communication Context Matters: Elicitation Task Shapes the Clinical Utility of Speech Markers in Psychosis.

El Mouslih C, Mackinley M, Dzialoszynski P, Lodhi R, Richard J, Titone D, Palaniyappan L

Neuropsychologia2026Senior author

DOI: 10.1016/j.neuropsychologia.2026.109587 PMID: 42772404

Social functioning and formal thought disorder in schizophrenia: A Bayesian meta-analysis.

Soldovieri CBC, Elleuch D, Ahrens J, Bambini V, Delgaram-Nejad O, Garani R, Harrison NA, Kircher T, Kuperberg G, Rossell SL, Sommer IE, Bosia M, Palaniyappan L

Schizophrenia research2026Senior author

DOI: 10.1016/j.schres.2026.07.028 PMID: 42566855

Language impoverishment in schizophrenia: neural networks and intervention

SupervisorCIHR2024Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Wang, Yingqi

Keywords: Controllability; Impoverished Thinking; Language Impoverishment; Language Network; Natural Language Processing; Negative Symptoms; Neuroimaging; Neuromodulation; Schizophrenia; Transcranial Magnetic Stimulation

$120,000

Schizophrenia and Cortical Association Fibres: A connectomic study

SupervisorCIHR2021Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Van Dyken, Peter

Keywords: Diffusion Weighted Imaging; Fmri; Graph Theory; Mri; Schizophrenia; Tractography

$105,000

The Impact of Cannabis Legalization and Availability on Incidence, Prevalence, and Health Services Utilization for Psychotic Disorders: Population-Based Evidence to Inform Policy Initiatives

Co-investigatorCIHR2020Catalyst Grant : Cannabis/MH - Cannabis use and psychosis in adult populations

Principal investigators: Anderson, Kelly K; Bromley, Sarah J

Keywords: Cannabis; Epidemiology; First-Episode Psychosis; Health Administrative Data; Health Services Research; Incidence; Prevalence; Psychotic Disorders; Public Mental Health

IMproved Personalized medicine through machine LEarning in MENTal disorders

Nominated PICIHR2018Team Grant: ERA-Net PerMed

Principal investigators: Palaniyappan, Lena K

Keywords: Brain Stimulation; Machine Learning; Neuroimaging; Schizophrenia

$440,025

Origins, Consequences and Outcomes of Neuroprogression in First Episode Schizophrenia

Nominated PICIHR2016Foundation Grant

Principal investigators: Palaniyappan, Lena K

Keywords: Connectivity; Magnetic Resonance Spectroscopy; Neuroimaging; Oxidative Stress; Positron Emission Tomography; Psychosis; Schizophrenia; Ultra-High Field Mri

$964,309

Understanding the Role of the Family Physician in Early Psychosis Intervention: A Mixed Methods Study

Co-investigatorCIHR2016Project Grant

Principal investigators: Anderson, Kelly K

Keywords: Access To Care; Early Intervention; Electronic Medical Records; Family Physician; First-Episode Psychosis; Health Administrative Data; Machine Learning; Mixed Methods; Primary Care; Qualitative Methods

$550,800

Myelin Mapping and Negative Symptoms of Schizophrenia

Nominated PICIHR2016Project Grant

Principal investigators: Palaniyappan, Lena K

Keywords: Anterior Cingulate Cortex; Connectivity; Magnetic Resonance Imaging; Negative Symptoms; Neuroimaging; Psychosis; Schizophrenia; Ultra-High Field Mri; White Matter

$566,100

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on November 9, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Lena Palaniyappan

Research

Latest papers

Latest funding

“I felt like that was a safe place to go”: a qualitative study of help-seeking experiences for early psychosis in primary care

Longitudinal inference of hippocampal volume and morphometric hippocampal-cortical covariance in psychosis.

Speech and Language Markers of Bipolar Disorder: Challenges and Opportunities.

Reading between the lines: Combining pause dynamics and semantic coherence for automated assessment of thought disorder.

Structural brain complexity is associated with linguistic complexity in psychosis.

Age of Onset, Brain Controllability, and Working Memory Performance in First-Episode Schizophrenia.

Putative glymphatic function and free water in schizophrenia: A 7T DTI study across psychosis stages.

Renaming vs. resolving: A reply to Bayl&#xe9; on discordance and disorganization.

Communication Context Matters: Elicitation Task Shapes the Clinical Utility of Speech Markers in Psychosis.

Social functioning and formal thought disorder in schizophrenia: A Bayesian meta-analysis.

Language impoverishment in schizophrenia: neural networks and intervention

Schizophrenia and Cortical Association Fibres: A connectomic study

The Impact of Cannabis Legalization and Availability on Incidence, Prevalence, and Health Services Utilization for Psychotic Disorders: Population-Based Evidence to Inform Policy Initiatives

IMproved Personalized medicine through machine LEarning in MENTal disorders

Origins, Consequences and Outcomes of Neuroprogression in First Episode Schizophrenia

Understanding the Role of the Family Physician in Early Psychosis Intervention: A Mixed Methods Study

Myelin Mapping and Negative Symptoms of Schizophrenia

Frequent collaborators

Lena Palaniyappan

Lena Palaniyappan

Kara Dempster

Suzanne Archie

Jordan Edwards

Paul Kurdyak

Ross Norman

Julie Richard

Ridha Joober

Chiachen Cheng

Martin Lepage

Martin Lepage

Ridha Joober

Ashok Malla

Priya Subramanian

Tara Elton-Marshall

David Benrimoh

Shehzad Ali

Richard Booth

Jean Theberge

Barbara Pavlova

Tara Elton-Marshall

Ali Khan

Rudolf Uher

Aristotle Voineskos

Ariel Graff-Guerrero

Jason Gilliland

Michael Bodnar

Arlene Macdougall

Mark Speechley

Hooman Ganjavi

Sherif Karama

Georg Northoff

Jim Reilly

Paul Frewen

Benicio Frey

Natasha Johnson

Andrew Olagunju

Luciano Minuzzi

Valerie Taylor

Renaming vs. resolving: A reply to Baylé on discordance and disorganization.