Faculty profile

Rima Slim

ResearcherHuman GeneticsMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Rima Slim

Researcher

Human Genetics

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
15 publications in the last five years, latest in 2026.
Senior (last) author on 8 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (10 CIHR), most recently in 2021.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Publications

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Grants

Publications by year

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Signals and details

Research

Molar Pregnancies Infertility Mechanism Of Disease Meiosis Miscarriages Mutations Oogenesis Spermatogenesis

Latest papers

EGCG improves follicular development of diabetic mice by the hypothalamic-pituitary-ovarian axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology · 2026
Report of two patients with variants in FOXL2 and KASH5 and review of gestational trophoblastic neoplasia after recurrent moles.
Journal of assisted reproduction and genetics · 2026 · senior author
Lessons learned from the exome sequencing of nine cases of infertility and the way forward.
Reproductive biomedicine online · 2026 · senior author

All 48 publications

Latest funding

Identify novel genes and mechanisms of molar pregnancies and reproductive failure
CIHR · 2021 · Nominated PI
$944,775
Identify novel genes and mechanisms of molar pregnancies and reproductive failure
CIHR · 2021 · Nominated PI
$100,000
The XXth World Congress of the International Society of Gestational Trophoblastic Diseases
CIHR · 2018 · Nominated PI
$10,000

All 10 grants and awards

48 publications.

EGCG improves follicular development of diabetic mice by the hypothalamic-pituitary-ovarian axis.

Gao HC, Lin J, Li LJ, Hu M, Zhao MH, Huang GA, Yin S, Xu P, Slim R, Ge ZJ, Zhao L

Phytomedicine : international journal of phytotherapy and phytopharmacology2026

DOI: 10.1016/j.phymed.2026.158654 PMID: 42542059

Report of two patients with variants in FOXL2 and KASH5 and review of gestational trophoblastic neoplasia after recurrent moles.

Saharan A, Hemida R, Lefebvre M, Bareke E, Carile V, Abdalla E, Majewski J, Slim R

Journal of assisted reproduction and genetics2026Senior author

DOI: 10.1007/s10815-026-03984-1 PMID: 42503564

Lessons learned from the exome sequencing of nine cases of infertility and the way forward.

Broojeni JV, Elmahdy M, Mitchell S, Rezaei M, Saharan A, Elhady G, Safwat S, Bareke E, Abdelrazek I, Xu C, Li L, Buckett W, Ao A, Miron P, Majewski J, Abdalla E, Slim R

Reproductive biomedicine online2026Senior author

DOI: 10.1016/j.rbmo.2025.105359 PMID: 41932285

Mild defects in follicular development and reproductive performance in the heterozygous Hfm1 female mouse.

Bhati L, Ene AC, Chen J, Liang M, Kazemi P, Martin JH, Slim R, Taketo T

Reproduction (Cambridge, England)2026

DOI: 10.1093/reprod/xaaf023 PMID: 41575512

Divergent roles of DNA methylation, TRIM28, and p53 surveillance in human embryonic and trophoblast stem cells.

Saini D, Katz MS, Beck SGA, Ireland TE, Ray S, Niloy AJ, Mazloomnejad R, Fleming A, Vetrici SC, Cinkornpumin JK, Sack T, Duhamel S, Slim R, Park M, Frost JM, Paul S, Martin RC, Pastor WA

bioRxiv : the preprint server for biology2025

DOI: 10.1101/2025.10.19.683051 PMID: 41279747

Two Novel Protein-Truncating Variants in NLRP2 and Their Functional Impacts on the Subcortical Maternal Complex.

Yalcin Z, Gao Z, Abdelrazek IM, Bareke E, Majewski J, Abdalla E, Tan SL, Li L, Slim R

Clinical genetics2025Senior author

DOI: 10.1111/cge.14718 PMID: 39905760

Is gestational trophoblastic neoplasia more common among women with recurrent hydatidiform moles and biallelic NLRP7 mutations? a 17-years prospective study from India.

Bagga R, Katoch T, Srinivasan R, Prasad GRV, Suri V, Saha PK, Slim R

European journal of obstetrics, gynecology, and reproductive biology2025Senior author

DOI: 10.1016/j.ejogrb.2025.114022 PMID: 40319759

Genetics and Genomics of Gestational Trophoblastic Disease.

Slim R

Hematology/oncology clinics of North America2024First author

DOI: 10.1016/j.hoc.2024.07.004 PMID: 39322462

Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles.

Rezaei M, Liang M, Yalcin Z, Martin JH, Kazemi P, Bareke E, Ge ZJ, Fardaei M, Benadiva C, Hemida R, Hassan A, Maher GJ, Abdalla E, Buckett W, Bolze PA, Sandhu I, Duman O, Agrawal S, Qian J, Vallian Broojeni J, Bhati L, Miron P, Allias F, Selim A, Fisher RA, Seckl MJ, Sauthier P, Touitou I, Tan SL, Majewski J, Taketo T, Slim R

The Journal of clinical investigation2024Senior author

DOI: 10.1172/jci170669 PMID: 39545410

A report of two homozygous TERB1 protein-truncating variants in two unrelated women with primary infertility.

Yalcin Z, Liang M, Abdelrazek IM, Friedrich C, Bareke E, Nabil A, Tüttelmann F, Majewski J, Abdalla E, Tan SL, Slim R

Journal of assisted reproduction and genetics2024Senior author

DOI: 10.1007/s10815-024-03031-x PMID: 38277113

Identify novel genes and mechanisms of molar pregnancies and reproductive failure

Nominated PICIHR2021Project Grant

Principal investigators: Slim, Rima

Keywords: Infertility; Mechanism Of Disease; Meiosis; Miscarriages; Molar Pregnancies; Mutations; Oogenesis; Spermatogenesis

$944,775

Identify novel genes and mechanisms of molar pregnancies and reproductive failure

Nominated PICIHR2021Operating Grant - PA: Genetics (Bridge Funding: Research Priorities)

Principal investigators: Slim, Rima

Keywords: Infertility; Mechanism Of Disease; Meiosis; Miscarriages; Molar Pregnancies; Mutations; Oogenesis; Spermatogenesis

$100,000

The XXth World Congress of the International Society of Gestational Trophoblastic Diseases

Nominated PICIHR2018Planning and Dissemination Grant - Institute Community Support

Principal investigators: Slim, Rima

Keywords: Abnormal Pregnancies; Benign And Malignant Tumors; Chemotherapy; Choriocarcinoma; Gestational Trophoblastic Tumors; International Meeting; Neoplasms; Oncology; Trophoblastic Diseases

$10,000

Delineate the Extent of Trophoblast Differentiation in Molar Pregnancies and their Malignancies

Nominated PICIHR2017Project Grant

Principal investigators: Slim, Rima

Keywords: Choriocarcinoma; Gestational Neoplasia; Nlrp7; Recurrent Hydatidiform Moles; Recurrent Molar Pregnancies; Rnaseq; Trophoblast Differentiation

$619,652

Identify New Genes for Recurrent Molar Pregnancies and Characterize mechanisms of mole formation

Nominated PICIHR2013Operating Grant

Principal investigators: Slim, Rima

Keywords: Aneuploidies; Exome Sequencing; Foetal Loss; Functional Studies; Immunofluorescence; Inflammation; Molar Pregnancies; Postzygotic Cleavage Abnormalities; Spontaneous Abortions; Stillbirth

$709,705

When a pregnancy leads to a tumor: Gestational Trophoblastic Diseases

Nominated PICIHR2013CIHR Café Scientifique Program

Principal investigators: Slim, Rima

Keywords: Abnormal Pregnancies; Infertility; Miscarriage; Molar Pregnancies; Placenta; Stillbirth; Tumour; Women'S Health

$3,000

NLRP7-based diagnosis of female reproduction wastage

Nominated PICIHR2012Proof of Principle Program - Phase I

Principal investigators: Slim, Rima

Keywords: Dna Test; Molar Pregnancies; Perinatal Mobidities; Placental Abnormalities; Recurrent Spontaneous Abortions

$160,000

Identify new causative genes for recurrent moles in China

Nominated PICIHR2012China-Canada Joint Health Research Initiative

Principal investigators: Slim, Rima; Qian, Jianhua

Keywords: Gene; Genetics; Human Molecular Genetics; Pregnancy; Reproduction

$225,000

Role of NLRP7 in the spectrum of reproductive wastage

Nominated PICIHR2010Operating Grant

Principal investigators: Slim, Rima

Keywords: Aneuploidies; Foetal Loss; Genetic Mapping; Inflammation; Maternal Defect; Molar Pregnancies; Positional Cloning; Postzygotic Cleavage Abnormalities; Spontaneous Abortions; Stillbirth

$371,673

Identify a second gene for recurrent molar pregnancies and dissect mechanisms of their formation

Nominated PICIHR2009Operating Grant

Principal investigators: Slim, Rima

Keywords: Aneuploidies; Genetic Mapping; Maternal Defect; Molar Pregnancies; Postional Cloning; Spontaneous Abortions

$374,418

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Rima Slim

Research

Latest papers

Latest funding

EGCG improves follicular development of diabetic mice by the hypothalamic-pituitary-ovarian axis.

Report of two patients with variants in FOXL2 and KASH5 and review of gestational trophoblastic neoplasia after recurrent moles.

Lessons learned from the exome sequencing of nine cases of infertility and the way forward.

Mild defects in follicular development and reproductive performance in the heterozygous Hfm1 female mouse.

Divergent roles of DNA methylation, TRIM28, and p53 surveillance in human embryonic and trophoblast stem cells.

Two Novel Protein-Truncating Variants in NLRP2 and Their Functional Impacts on the Subcortical Maternal Complex.

Is gestational trophoblastic neoplasia more common among women with recurrent hydatidiform moles and biallelic NLRP7 mutations? a 17-years prospective study from India.

Genetics and Genomics of Gestational Trophoblastic Disease.

Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles.

A report of two homozygous TERB1 protein-truncating variants in two unrelated women with primary infertility.

Identify novel genes and mechanisms of molar pregnancies and reproductive failure

Identify novel genes and mechanisms of molar pregnancies and reproductive failure

The XXth World Congress of the International Society of Gestational Trophoblastic Diseases

Delineate the Extent of Trophoblast Differentiation in Molar Pregnancies and their Malignancies

Identify New Genes for Recurrent Molar Pregnancies and Characterize mechanisms of mole formation

When a pregnancy leads to a tumor: Gestational Trophoblastic Diseases

NLRP7-based diagnosis of female reproduction wastage

Identify new causative genes for recurrent moles in China

Role of NLRP7 in the spectrum of reproductive wastage

Identify a second gene for recurrent molar pregnancies and dissect mechanisms of their formation

Frequent collaborators

Jacek Majewski

Asangla Ao

Teruko Taketo

Richard Brown

Lucy Gilbert

Salman Qureshi

Jianhua Qian

Morag Park

Rosanna Weksberg

Morag Park

Maya Saleh