Shan Cen, McGill University

Research

Hiv Resting Cd4+ T Cells Samhd1 Transmission Transmitted/Founder Viruses

Latest papers

Human MxB Inhibits the Replication of Hepatitis C Virus.
Journal of virology · 2019 · senior author
The interferon-inducible MxB protein inhibits HIV-1 infection.
Cell host & microbe · 2013
The roles of APOBEC3G complexes in the incorporation of APOBEC3G into HIV-1.
PloS one · 2013 · senior author

All 13 publications

Latest funding

Study the role of SAMHD1 in HIV-1 transmission
CIHR · 2013 · Principal investigator
$225,000
The potential of APOBEC3G in the development of a novel anti-HIV-1 therapeutic.
CIHR · 2008 · Nominated PI
$60,000
The potential of APOBEC3G in the development of a novel anti-HIV-1 therapeutic.
CIHR · 2008 · Nominated PI
$327,993

All 3 grants and awards

13 publications.

01

Human MxB Inhibits the Replication of Hepatitis C Virus.

Yi DR, An N, Liu ZL, Xu FW, Raniga K, Li QJ, Zhou R, Wang J, Zhang YX, Zhou JM, Zhang LL, An J, Qin CF, Guo F, Li XY, Liang C, Cen S

Journal of virology2019Senior author

DOI: 10.1128/jvi.01285-18 PMID: 30333168

02

The interferon-inducible MxB protein inhibits HIV-1 infection.

Liu Z, Pan Q, Ding S, Qian J, Xu F, Zhou J, Cen S, Guo F, Liang C

Cell host & microbe2013

DOI: 10.1016/j.chom.2013.08.015 PMID: 24055605

03

The roles of APOBEC3G complexes in the incorporation of APOBEC3G into HIV-1.

Ma J, Li X, Xu J, Zhang Q, Liu Z, Jia P, Zhou J, Guo F, You X, Yu L, Zhao L, Jiang J, Cen S

PloS one2013Senior author

DOI: 10.1371/journal.pone.0074892 PMID: 24098356

04

Retraction: The cellular source for APOBEC3G's incorporation into HIV-1.

Ma J, Li X, Xu J, Zhang Q, Liu Z, Jia P, Zhou J, Guo F, You X, Yu L, Zhao L, Jiang J, Cen S

Retrovirology2011Senior author

DOI: 10.1186/1742-4690-8-88 PMID: 22054052

05

Methods for analysis of incorporation and annealing methods for analysis of tRNA(Lys) in HIV-1.

Cen S, Guo F, Kleiman L

Methods in molecular biology (Clifton, N.J.)2009First author

DOI: 10.1007/978-1-59745-170-3_16 PMID: 19020829

06

Interactions of reverse transcriptase sequences in Pol with Gag and LysRS in the HIV-1 tRNALys3 packaging/annealing complex.

Saadatmand J, Guo F, Cen S, Niu M, Kleiman L

Virology2008

DOI: 10.1016/j.virol.2008.07.015 PMID: 18708237

07

Function analysis of sequences in human APOBEC3G involved in Vif-mediated degradation.

Zhang L, Saadatmand J, Li X, Guo F, Niu M, Jiang J, Kleiman L, Cen S

Virology2008Senior author

DOI: 10.1016/j.virol.2007.08.027 PMID: 17916373

08

APOBEC3G inhibits DNA strand transfer during HIV-1 reverse transcription.

Li XY, Guo F, Zhang L, Kleiman L, Cen S

The Journal of biological chemistry2007Senior author

DOI: 10.1074/jbc.m703423200 PMID: 17855362

09

The interaction of APOBEC3G with human immunodeficiency virus type 1 nucleocapsid inhibits tRNA3Lys annealing to viral RNA.

Guo F, Cen S, Niu M, Yang Y, Gorelick RJ, Kleiman L

Journal of virology2007

DOI: 10.1128/jvi.00162-07 PMID: 17670826

10

Inhibition of initiation of reverse transcription in HIV-1 by human APOBEC3F.

Yang Y, Guo F, Cen S, Kleiman L

Virology2007

DOI: 10.1016/j.virol.2007.03.022 PMID: 17459442

Study the role of SAMHD1 in HIV-1 transmission

Principal investigatorCIHR2013China-Canada Joint Health Research Initiative

Principal investigators: Liang, Chen; Cen, Shan

Keywords: Hiv; Resting Cd4+ T Cells; Samhd1; Transmission; Transmitted/Founder Viruses

$225,000

The potential of APOBEC3G in the development of a novel anti-HIV-1 therapeutic.

Nominated PICIHR2008New Investigator Award - PA: HIV/AIDS Biomedical/Clinical Research

Principal investigators: Cen, Shan

Keywords: Aids; Apobec Superfamily; Apobec3g; Assembly; Deaminase; Encapsidation

$60,000

The potential of APOBEC3G in the development of a novel anti-HIV-1 therapeutic.

Nominated PICIHR2008Operating Grant - Priority Announcement: Canadian HIV Vaccine Initiative

Principal investigators: Cen, Shan

Keywords: Aids; Apobec; Deamination; Hiv-1; Integration; Ncp7

$327,993

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Lady Davis Institute for Medical Research
AIDS Pathogenesis Unit
Other

Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Lawrence Kleiman

Lady Davis Institute for Medical Research

9 shared papers, latest 2009

Chen Liang

AIDS Pathogenesis Unit

2 shared papers, latest 2019

Write to this professor

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Applying for

Paper to mention

Subject: Prospective PhD student: Hiv Dear Professor Cen, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Human MxB Inhibits the Replication of Hepatitis C Virus." (2019), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]