Weiya Ma, McGill University

Latest papers

Effects of prolonged fixation on vascular biomarkers in postmortem human brains.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
Differential effects of prolonged post-fixation on immunohistochemical and histochemical staining for postmortem human brains.
Frontiers in neuroanatomy · 2024 · first author
Chronic tianeptine induces tolerance in analgesia and hyperlocomotion via mu-opioid receptor activation in mice.
Frontiers in psychiatry · 2023

All 29 publications

Latest funding

Role of PGE2-induced up-regulation of TRPV1 channel in prolonged nociceptor sensitization and potentiation
NSERC · 2017 · Principal investigator
$168,000
Ultracentrifugation for the biochemical characterization of biomarkers involved in neurobiological functions
NSERC · 2013 · Principal investigator
$78,654
Prostaglandin E2 EP receptor trafficking and nociception
NSERC · 2011 · Principal investigator
$150,000

All 3 grants and awards

29 publications.

01

Effects of prolonged fixation on vascular biomarkers in postmortem human brains.

Frigon EM, Ma W, Tremblay C, Mirault D, Turecki G, Mechawar N, Boire D, Maranzano J, Dadar M, Zeighami Y

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2026

DOI: 10.1177/0271678x261461536 PMID: 42257420

02

Differential effects of prolonged post-fixation on immunohistochemical and histochemical staining for postmortem human brains.

Ma W, Frigon EM, Maranzano J, Zeighami Y, Dadar M

Frontiers in neuroanatomy2024First author

DOI: 10.3389/fnana.2024.1477973 PMID: 39611118

03

Chronic tianeptine induces tolerance in analgesia and hyperlocomotion via mu-opioid receptor activation in mice.

Allain F, Ehrlich AT, McNicholas M, Gross F, Ma W, Kieffer BL, Darcq E

Frontiers in psychiatry2023

DOI: 10.3389/fpsyt.2023.1186397 PMID: 37287667

04

Investigating the "two-hit hypothesis": Effects of prenatal maternal immune activation and adolescent cannabis use on neurodevelopment in mice.

Guma E, Cupo L, Ma W, Gallino D, Moquin L, Gratton A, Devenyi GA, Chakravarty MM

Progress in neuro-psychopharmacology & biological psychiatry2023

DOI: 10.1016/j.pnpbp.2022.110642 PMID: 36150422

05

Chronic generalized pain disrupts whole brain functional connectivity in mice.

Nasseef MT, Ma W, Singh JP, Dozono N, Lançon K, Séguéla P, Darcq E, Ueda H, Kieffer BL

Brain imaging and behavior2021

DOI: 10.1007/s11682-020-00438-9 PMID: 33428113

06

Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies.

Rahman MT, Decker AM, Laudermilk L, Maitra R, Ma W, Ben Hamida S, Darcq E, Kieffer BL, Jin C

Journal of medicinal chemistry2021

DOI: 10.1021/acs.jmedchem.1c01075 PMID: 34387471

07

Design, Synthesis, and Structure-Activity Relationship Studies of (4-Alkoxyphenyl)glycinamides and Bioisosteric 1,3,4-Oxadiazoles as GPR88 Agonists.

Rahman MT, Decker AM, Langston TL, Mathews KM, Laudermilk L, Maitra R, Ma W, Darcq E, Kieffer BL, Jin C

Journal of medicinal chemistry2020

DOI: 10.1021/acs.jmedchem.0c01581 PMID: 33205975

08

PGE2/EP4 receptor and TRPV1 channel are involved in repeated restraint stress-induced prolongation of sensitization pain evoked by subsequent PGE2 challenge.

Ma W, Li L, Xing S

Brain research2019First author

DOI: 10.1016/j.brainres.2019.146335 PMID: 31302096

09

Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice.

Nasseef MT, Singh JP, Ehrlich AT, McNicholas M, Park DW, Ma W, Kulkarni P, Kieffer BL, Darcq E

ACS pharmacology & translational science2019

DOI: 10.1021/acsptsci.9b00021 PMID: 32259060

10

Preferred recycling pathway by internalized PGE2 EP4 receptor following agonist stimulation in cultured dorsal root ganglion neurons contributes to enhanced EP4 receptor sensitivity.

St-Jacques B, Ma W

Neuroscience2016Senior author

DOI: 10.1016/j.neuroscience.2016.04.005 PMID: 27060485

Role of PGE2-induced up-regulation of TRPV1 channel in prolonged nociceptor sensitization and potentiation

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Ma, Weiya

$168,000

Ultracentrifugation for the biochemical characterization of biomarkers involved in neurobiological functions

Principal investigatorNSERC2013Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Ma, Weiya

$78,654

Prostaglandin E2 EP receptor trafficking and nociception

Principal investigatorNSERC2011Discovery Grants Program - Individual

Principal investigators: Ma, Weiya

$150,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Psychiatry
Anatomy
Anatomie

Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Denis Boire

Anatomie

1 shared papers, latest 2026

Write to this professor

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Subject: Prospective PhD student Dear Professor Ma, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Effects of prolonged fixation on vascular biomarkers in postmortem human brains." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Weiya Ma

Latest papers

Latest funding

Effects of prolonged fixation on vascular biomarkers in postmortem human brains.

Differential effects of prolonged post-fixation on immunohistochemical and histochemical staining for postmortem human brains.

Chronic tianeptine induces tolerance in analgesia and hyperlocomotion via mu-opioid receptor activation in mice.

Investigating the "two-hit hypothesis": Effects of prenatal maternal immune activation and adolescent cannabis use on neurodevelopment in mice.

Chronic generalized pain disrupts whole brain functional connectivity in mice.

Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies.

Design, Synthesis, and Structure-Activity Relationship Studies of (4-Alkoxyphenyl)glycinamides and Bioisosteric 1,3,4-Oxadiazoles as GPR88 Agonists.

PGE2/EP4 receptor and TRPV1 channel are involved in repeated restraint stress-induced prolongation of sensitization pain evoked by subsequent PGE2 challenge.

Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice.

Preferred recycling pathway by internalized PGE2 EP4 receptor following agonist stimulation in cultured dorsal root ganglion neurons contributes to enhanced EP4 receptor sensitivity.

Role of PGE2-induced up-regulation of TRPV1 channel in prolonged nociceptor sensitization and potentiation

Ultracentrifugation for the biochemical characterization of biomarkers involved in neurobiological functions

Prostaglandin E2 EP receptor trafficking and nociception

Frequent collaborators

Josefina Maranzano

Mahsa Dadar

Yashar Zeighami

Gustavo Turecki

Naguib Mechawar

Denis Boire