Faculty profile

Naguib Mechawar

ResearcherPsychiatryMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Naguib Mechawar

Researcher

Psychiatry

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
59 publications in the last five years, latest in 2026.
Senior (last) author on 22 recent papers, a sign of leading a research group.
Principal investigator on 9 research grants (5 CIHR, 4 NSERC), most recently in 2025.
Supervisor on 4 trainee awards (4 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

150

Publications

442

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Suicide Neuroplasticity Child Abuse Depression Adult Brain Neurogenesis Hippocampus Human Brain Major Depression

Latest papers

Multi-omics characterization of astrocyte subtypes reveals spatially coordinated astrocyte downregulation in depression.
bioRxiv : the preprint server for biology · 2026
Comprehensive analysis of cytokines in depression: independent data from patient plasma and post-mortem ventromedial prefrontal cortex.
Brain, behavior, & immunity - health · 2026 · senior author
Effects of prolonged fixation on vascular biomarkers in postmortem human brains.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026

All 150 publications

Latest funding

Characterization of human adult hippocampal neurogenesis in major depression
CIHR · 2025 · Nominated PI
$761,176
Allostatic Load and Transdiagnostic Dimensions of Psychiatric Emergency Patients: The Signature Biobank
CIHR · 2025 · Co-investigator
$841,500
Exploring how microglial and astrocytic regulation of synapses may be contributing to suicide in youth
CIHR · 2025 · Supervisor
$120,000

All 28 grants and awards

150 publications.

Multi-omics characterization of astrocyte subtypes reveals spatially coordinated astrocyte downregulation in depression.

Mitsuhashi H, Rao HR, Amadei S, Chawla A, Davoli MA, Mechawar N, Turecki G, Nagy C

bioRxiv : the preprint server for biology2026

DOI: 10.64898/2026.07.02.735636 PMID: 42427711

Comprehensive analysis of cytokines in depression: independent data from patient plasma and post-mortem ventromedial prefrontal cortex.

Rahimian R, Hagenberg J, Belliveau C, Chen R, Théberge S, Fakhfouri G, Wakid M, Binder E, Turecki G, Knauer-Arloth J, Mechawar N

Brain, behavior, & immunity - health2026Senior author

DOI: 10.1016/j.bbih.2026.101245 PMID: 42094851

Effects of prolonged fixation on vascular biomarkers in postmortem human brains.

Frigon EM, Ma W, Tremblay C, Mirault D, Turecki G, Mechawar N, Boire D, Maranzano J, Dadar M, Zeighami Y

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2026

DOI: 10.1177/0271678x261461536 PMID: 42257420

Choroid plexus inflammation in bipolar disorder.

Figueroa Velez D, Rahimian R, Hehnly C, Benson JC, Sacharczyk I, Turecki G, Mechawar N, Lehtinen MK

Brain, behavior, and immunity2026

DOI: 10.1016/j.bbi.2026.106598 PMID: 41980683

Dopamine drives persistent remodelling of the maternal brain.

O'Chan JC, Di Salvo G, Cunningham AM, Dutta S, Brindley E, Weekley BH, Chen W, Iyer RR, Wan E, Zhang C, Mechawar N, Turecki G, Maze I

Nature2026

DOI: 10.1038/s41586-026-10509-4 PMID: 42162419

Alterations of microRNAs across human and mouse limbic brain areas: molecular mechanisms and biological processes involved in major depressive disorder.

Saleri S, Marizzoni M, Genini P, Galbiati C, Cattaneo A, Turecki G, Grosskopf H, Steinacker P, Otto M, Poggi G, Pryce CR, Mechawar N, Cattane N

Neurobiology of stress2026

DOI: 10.1016/j.ynstr.2026.100816 PMID: 42064576

Characterizing neuronal cell bodies in white matter tracts of the human brain.

VanderBerg D, Perlman K, Davoli MA, Turecki G, Mechawar N

Brain structure & function2026Senior author

DOI: 10.1007/s00429-026-03112-w PMID: 42082796

Reconciling the neurogenic hypothesis of depression with recent advances in adult hippocampal neurogenesis research in humans.

Simard S, Mechawar N

Molecular psychiatry2026Senior author

DOI: 10.1038/s41380-026-03896-7 PMID: 42754620

TRP canonical 4 and/or 5 channel inhibition reduces aversion- and increases reward-responding in chronically stressed mice.

Poggi G, Queisser D, Senn A, Sigrist H, Kúkeľová D, Madur L, Cuomo-Haymour N, Robert M, Schmid S, Portalés A, Simard S, Mechawar N, Hengerer B, Just S, Pryce CR

British journal of pharmacology2026

DOI: 10.1111/bph.70305 PMID: 41423221

[The data and metadata repository of the Québec Mental Health Alliance].

Ujevco A, Le Page C, Corbière M, Guay S, Lepage M, Hébert M, Juster RP, Cipriani E, Giguère CÉ, Cailhol L, Orban P, Potvin S, Baril AA, Beaudry T, Blais-Michaud S, Chakravarty M, Dai A, Ducharme S, Marquet P, Morin C, Mechawar N, Poline JB, Roy M, Savard C, Urchs S, Taschereau-Dumouchel V

Sante mentale au Quebec2026

PMID: 42550440

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Naguib Mechawar

Research

Latest papers

Latest funding

Multi-omics characterization of astrocyte subtypes reveals spatially coordinated astrocyte downregulation in depression.

Comprehensive analysis of cytokines in depression: independent data from patient plasma and post-mortem ventromedial prefrontal cortex.

Effects of prolonged fixation on vascular biomarkers in postmortem human brains.

Choroid plexus inflammation in bipolar disorder.

Dopamine drives persistent remodelling of the maternal brain.

Alterations of microRNAs across human and mouse limbic brain areas: molecular mechanisms and biological processes involved in major depressive disorder.

Characterizing neuronal cell bodies in white matter tracts of the human brain.

Reconciling the neurogenic hypothesis of depression with recent advances in adult hippocampal neurogenesis research in humans.

TRP canonical 4 and/or 5 channel inhibition reduces aversion- and increases reward-responding in chronically stressed mice.

[The data and metadata repository of the Qu&#xe9;bec Mental Health Alliance].

Frequent collaborators

Gustavo Turecki

Corina Nagy

Carl Ernst

Bruno Giros

Bruno Giros

Kathryn Vaillancourt

Salah El Mestikawy

Jane Foster

Alexey Kostikov

Jean-Paul Soucy

Caroline Menard

Pedro Rosa-Neto

Sylvain Williams

Pierre Thibault

Claire-Dominique Walker

Pierre Blier

John Kim

Etienne Sibille

Liam Crapper

Benicio Frey

Nahum Sonenberg

Moshe Szyf

Paul Pavlidis

Rudolf Uher

Simon Ducharme

Marie-Jeanne Kergoat

Myriam Srour

Soham Rej

Argel Aguilar Valles

Yue Li

Romina Mizrahi

Massimiliano Orri

Flavie Lavoie-Cardinal

Roumen Milev

Roy Dudley

Mahsa Dadar

Peter Giacobbe

Yashar Zeighami

Mallar Chakravarty

Pierre Marquet

[The data and metadata repository of the Québec Mental Health Alliance].