Jamila Chakir, Université Laval

Research

Airway Epithelium Airway Fibroblsats Airway Remodelling Asthma Communication Exosomes

Latest papers

Constrained differentiation of human pluripotent stem cells into homogeneous bronchial epithelium on a fibroblast seeded matrix.
American journal of respiratory cell and molecular biology · 2026
Evaluation of the Effects of Tetrahydrocannabinol (THC) and Cannabidiol (CBD) on Gingival and Skin Keratinocyte Growth, Migration, Metabolic Activity, and Pro-Inflammatory Cytokine Secretion.
Biomedicines · 2025
Discrepancy in the suppressive function of regulatory T cells in allergic asthmatic vs. allergic rhinitis subjects upon low-dose allergen challenges.
Frontiers in allergy · 2023 · senior author

All 40 publications

Latest funding

Role of exosomes in cellular communication in asthma
CIHR · 2018 · Nominated PI
$833,850
Comprehensive analysis of IL1R1 and IL1R2 genes in asthma considering smoking status
CIHR · 2013 · Co-investigator
$100,000
Regulation of Th17 cells by fibroblast microenvironment in the airways
NSERC · 2011 · Principal investigator
$30,000

All 5 grants and awards

40 publications.

01

Constrained differentiation of human pluripotent stem cells into homogeneous bronchial epithelium on a fibroblast seeded matrix.

Foisset F, Lehalle C, Nasri A, Bourdais C, Urena C, Morichon L, Cœur A, Petit A, Vachier I, Muller Q, Flacher V, Chakir J, Massiera G, Sridurai V, Ahmed E, Assou S, Bourdin A, Frossard N, De Vos J

American journal of respiratory cell and molecular biology2026

DOI: 10.1093/ajrcmb/aanag153 PMID: 42569932

02

Evaluation of the Effects of Tetrahydrocannabinol (THC) and Cannabidiol (CBD) on Gingival and Skin Keratinocyte Growth, Migration, Metabolic Activity, and Pro-Inflammatory Cytokine Secretion.

Bahraminia M, Laaboudi FZ, Romanet C, Zhang Z, Chakir J, Béland F, Rouabhia M

Biomedicines2025

DOI: 10.3390/biomedicines13102541 PMID: 41153821

03

Discrepancy in the suppressive function of regulatory T cells in allergic asthmatic vs. allergic rhinitis subjects upon low-dose allergen challenges.

Klein M, Plante S, Boulay MÈ, Boulet LP, Chakir J

Frontiers in allergy2023Senior author

DOI: 10.3389/falgy.2023.1296601 PMID: 38106504

04

S100A alarmins and thymic stromal lymphopoietin (TSLP) regulation in severe asthma following bronchial thermoplasty.

Gagnon PA, Klein M, De Vos J, Biardel S, Côté A, Godbout K, Laviolette M, Laprise C, Assou S, Chakir J

Respiratory research2023Senior author

DOI: 10.1186/s12931-023-02604-1 PMID: 37996952

05

Bronchial thermoplasty attenuates bronchodilator responsiveness.

Henry C, Biardel S, Boucher M, Godbout K, Chakir J, Côté A, Laviolette M, Bossé Y

Respiratory medicine2023

DOI: 10.1016/j.rmed.2023.107340 PMID: 37422022

06

The reduction of airway smooth muscle by bronchial thermoplasty stands the test of time.

Gagnon PA, Côté A, Klein M, Biardel S, Laviolette M, Godbout K, Bossé Y, Chakir J

ERJ open research2023Senior author

DOI: 10.1183/23120541.00024-2023 PMID: 37404844

07

Effect of cannabis smoke condensate on human nasal epithelial cell adhesion, growth, and migration.

Rouabhia M, Piché M, Hazzi C, Corriveau MN, Chakir J

American journal of otolaryngology2023Senior author

DOI: 10.1016/j.amjoto.2023.103890 PMID: 37058911

08

Comparison of circulating fibrocytes from non-asthmatic patients with seasonal allergic rhinitis between in and out of pollen season samples.

Côté MÈ, Boulay MÈ, Plante S, Côté A, Chakir J, Boulet LP

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2022

DOI: 10.1186/s13223-022-00663-5 PMID: 35296352

09

Bronchial thermoplasty: The heat that reprograms the airways?

Chakir J, Gagnon PA, Laviolette M

The Journal of allergy and clinical immunology2021First author

DOI: 10.1016/j.jaci.2021.09.004 PMID: 34509527

10

Effect of e-cigarettes on nasal epithelial cell growth, Ki67 expression, and pro-inflammatory cytokine secretion.

Rouabhia M, Piché M, Corriveau MN, Chakir J

American journal of otolaryngology2020Senior author

DOI: 10.1016/j.amjoto.2020.102686 PMID: 32866847

Role of exosomes in cellular communication in asthma

Nominated PICIHR2018Project Grant

Principal investigators: Chakir, Jamila

Keywords: Airway Epithelium; Airway Fibroblsats; Airway Remodelling; Asthma; Communication; Exosomes

$833,850

Comprehensive analysis of IL1R1 and IL1R2 genes in asthma considering smoking status

Co-investigatorCIHR2013Catalyst Grant: Environments, Genes and Chronic Disease

Principal investigators: Laprise, Catherine; Bouchard, Luigi

Keywords: Asthma; Atopy; Bronchial Epithelial Cells; Epigenetics; Expression; Genetics; Il1r1; Il1r2; Immunohistochemistry; Protein Levels

$100,000

Regulation of Th17 cells by fibroblast microenvironment in the airways

Principal investigatorNSERC2011Discovery Grants Program - Individual

Principal investigators: Chakir, Jamila

$30,000

Epithelial cell-fibroblast interplay a key pathway to understand airway remodelling in asthma

Nominated PICIHR2011Operating Grant

Principal investigators: Chakir, Jamila

Keywords: Airway Remodelling; Apoptosis; Asthma; Bronchial Epithelial Cells; Bronchial Fibroblasts; Cytokines; Epithelial Cell Proliferation; Growth Factors; Kgf Regulation; Tissue Engineering

$592,821

CIHR - Quebec Respiratory Health Training Program

Co-investigatorCIHR2008Training Grant

Principal investigators: Maltais, François; Berthiaume, Yves; Martin, James G; Rousseau, Eric C; Schwartzman, Kevin

Keywords: Knowledge Transfer; Respiratory Biology; Respiratory Epidemiology And Health; Student Exchange Programs; Transdisciplinary Training And Research

$1,950,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Médecine
Surgery
Basic Sciences
Other

Co-authors at Université Laval, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Catherine Laprise

Basic Sciences

3 shared papers, latest 2023

Manali Mukherjee

Medicine

1 shared papers, latest 2018

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mention

Subject: Prospective PhD student: Airway Epithelium Dear Professor Chakir, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Constrained differentiation of human pluripotent stem cells into homogeneous bronchial epithelium on a fibroblast seeded matrix." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Jamila Chakir

Research

Latest papers

Latest funding

Constrained differentiation of human pluripotent stem cells into homogeneous bronchial epithelium on a fibroblast seeded matrix.

Evaluation of the Effects of Tetrahydrocannabinol (THC) and Cannabidiol (CBD) on Gingival and Skin Keratinocyte Growth, Migration, Metabolic Activity, and Pro-Inflammatory Cytokine Secretion.

Discrepancy in the suppressive function of regulatory T cells in allergic asthmatic vs. allergic rhinitis subjects upon low-dose allergen challenges.

S100A alarmins and thymic stromal lymphopoietin (TSLP) regulation in severe asthma following bronchial thermoplasty.

Bronchial thermoplasty attenuates bronchodilator responsiveness.

The reduction of airway smooth muscle by bronchial thermoplasty stands the test of time.

Effect of cannabis smoke condensate on human nasal epithelial cell adhesion, growth, and migration.

Comparison of circulating fibrocytes from non-asthmatic patients with seasonal allergic rhinitis between in and out of pollen season samples.

Bronchial thermoplasty: The heat that reprograms the airways?

Effect of e-cigarettes on nasal epithelial cell growth, Ki67 expression, and pro-inflammatory cytokine secretion.

Role of exosomes in cellular communication in asthma

Comprehensive analysis of IL1R1 and IL1R2 genes in asthma considering smoking status

Regulation of Th17 cells by fibroblast microenvironment in the airways

Epithelial cell-fibroblast interplay a key pathway to understand airway remodelling in asthma

CIHR - Quebec Respiratory Health Training Program

Frequent collaborators

Mahmoud Rouabhia

Philippe Joubert

Nicolas Flamand

Catherine Laprise

Fawzi Aoudjit

Olivier Boucherat

Lucie Jeannotte

Catherine Laprise

John Paul Oliveria

Ze Zhang

Parameswaran Krishna Nair

Elyse Bissonnette

Gail Gauvreau

Roma Sehmi

Manali Mukherjee