Faculty profile

Nicolas Flamand

ResearcherMédecineUniversité Laval

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.

Nicolas Flamand

Researcher

Médecine

Health Sciences

Université Laval

Quebec City, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
52 publications in the last five years, latest in 2026.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (3 NSERC, 2 CIHR), most recently in 2021.
Supervised 5 trainees who won CIHR awards, most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

107

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Bioactive Lipid Cell Biology Eicosanoid Endocannbinoid Inflammation Lc-Ms/Ms Lipidomic Macrophage

Latest papers

Brain DHA increases in APOE3, but not in APOE4 mice, despite robust brain EPA increase during LPC n-3 supplementation in both genotypes.
The Journal of nutritional biochemistry · 2026
Alteration of epidermal lipid metabolism by 2-linoleoylglycerol in a 3D skin model.
Scientific reports · 2026
Fattening Physiology in a Long-Distance Migrant: Interplay between Baseline Corticosterone, Diet, and the Endocannabinoidome.
Ecological and evolutionary physiology · 2026

All 107 publications

Latest funding

Modulation of sterile inflammation by dietary omega-3 fatty acids through modified production of platelet microvesicles in mouse models of inflammatory arthritis
CIHR · 2024 · Co-investigator
$753,525
Synthesis, characterization, and in vivo identification of novel oxyendocannabinoidome metabolites
CIHR · 2023 · Supervisor
$90,000
COVID-19 Variant Supplement - Understanding the pathogenesis of COVID-19
CIHR · 2021 · Co-investigator
$50,000

All 16 grants and awards

107 publications.

Brain DHA increases in APOE3, but not in APOE4 mice, despite robust brain EPA increase during LPC n-3 supplementation in both genotypes.

Andriambelo B, Vachon A, Dansereau MA, Dumais É, Flamand N, Laurent B, Plourde M

The Journal of nutritional biochemistry2026

DOI: 10.1016/j.jnutbio.2026.110376 PMID: 41962782

Alteration of epidermal lipid metabolism by 2-linoleoylglycerol in a 3D skin model.

Tremblay A, Simard M, Larouche A, Dumais É, Julien P, Flamand N, Pouliot R

Scientific reports2026

DOI: 10.1038/s41598-026-60336-w PMID: 42431977

Fattening Physiology in a Long-Distance Migrant: Interplay between Baseline Corticosterone, Diet, and the Endocannabinoidome.

Colin MM, Grentzmann IP, Gauthier G, Angelier F, Parenteau C, Flamand N, Dumais E, Silvestri C, Legagneux P

Ecological and evolutionary physiology2026

DOI: 10.1086/742374 PMID: 42612238

Biosynthesis and analytics of specialized pro-resolving mediators: facts and faults.

Schebb NH, Kühn H, Kampschulte N, Flamand N, Peters-Golden M, Jakobsson PJ, Claesson HE, Weylandt KH, Rohwer N, Saul MJ, Proschak E, Brüne B, Garscha U, Maier TJ, Patrignani P, Gijón MA, Schopfer FJ, Gelhaus SL, Gelb MH, Murphy RC, Skarke C, Brash AR, Freeman BA, Blair IA, Gilroy DW, Geisslinger G, Hanson J, Ekroos K, FitzGerald GA, Kahnt AS, O'Donnell VB, Alnouri MW, Offermanns S, Steinhilber D

Journal of lipid research2026

DOI: 10.1016/j.jlr.2026.101133 PMID: 42665162

Intestinal colonization of germ-free mice with indole-producing E. coli modulates the central and peripheral endocannabinoidome.

Giorgini G, Mir HD, Etienne C, Dumais É, Maximin E, Silvestri C, Flamand N, Naudon L, Rabot S, Di Marzo V

Journal of lipid research2026

DOI: 10.1016/j.jlr.2026.101070 PMID: 42203173

Linoleic acid concentration at the air-liquid interface is key for optimal incorporation into skin model lipidome.

Tremblay A, Larouche A, Simard M, Dumais É, Julien P, Flamand N, Pouliot R

Frontiers in physiology2026

DOI: 10.3389/fphys.2026.1838020 PMID: 42441238

Longitudinal changes in endocannabinoidome and dietary lipid profile in severe obesity: impact of sleeve gastrectomy.

St-Arnaud G, Daoust J, Pelletier M, Gagnon C, Biertho L, Bouvet-Bouchard L, Dumais E, Flamand N, Di Marzo V, Michaud A, Veilleux A

Lipids in health and disease2026

DOI: 10.1186/s12944-026-02988-1 PMID: 42298563

Seal and fish oils partially counteract inflammation and modulate endocannabinoidome lipid and oxylipin alterations in DSS-induced colitis.

Giorgini G, Leblanc N, Muller C, Dumais E, Labbé-Blondeau MN, Thibodeau A, Flamand N, Di Marzo V, Silvestri C

Scientific reports2026

DOI: 10.1038/s41598-026-54447-7 PMID: 42230679

Circadian disruption elicits sex-specific gut microbiota, endocannabinoidome, and lipid mediator responses.

Pashaki PA, Niepokny TD, Khalilzadehsabet T, Dumais E, Flamand N, Di Marzo V, Mintz EM, Silvestri C

The FEBS journal2026

DOI: 10.1111/febs.70592 PMID: 42171003

Impact of Oral Cannabinoids on the Endocannabinoidome and Gut Microbiome in People with HIV on Antiretroviral Therapy (CTN PT028 Pilot Clinical Trial).

Giorgini G, Silvestri C, Mboumba Bouassa RS, Muller C, Frias Boligan K, Kalkan H, Routy JP, Flamand N, Di Marzo V, Jenabian MA, Costiniuk CT

Cannabis and cannabinoid research2026

DOI: 10.1177/25785125251366052 PMID: 40879543

Modulation of sterile inflammation by dietary omega-3 fatty acids through modified production of platelet microvesicles in mouse models of inflammatory arthritis

Co-investigatorCIHR2024Project Grant

Principal investigators: Surette, Marc E; Boudreau, Luc

Keywords: Dietary Fatty Acids; Inflammation; Lipid Mediators; Platelets

$753,525

Synthesis, characterization, and in vivo identification of novel oxyendocannabinoidome metabolites

SupervisorCIHR2023CIHR Fellowship

Principal investigators: Muller, Chanté

Keywords: Endocannabinoid System; Endocannabinoids; Leukocytes

$90,000

COVID-19 Variant Supplement - Understanding the pathogenesis of COVID-19

Co-investigatorCIHR2021Operating Grant: SARS-CoV-2 variants supplement stream 1

Principal investigators: Flamand, Louis

Keywords: Cytokines; Inflammation; Leukocytes; Lipid Mediators; Lungs; Macrophages; Novel Coronavirus; Platelets

$50,000

COVID-19 Variant Network - Understanding the pathogenesis of COVID-19

Co-investigatorCIHR2021Operating Grant: SARS-CoV-2 variants supplement stream 2

Principal investigators: Flamand, Louis

Keywords: Cytokines; Inflammation; Leukocytes; Lipid Mediators; Lungs; Macrophages; Novel Coronavirus; Platelets

$100,000

Cellular and molecular mechanisms involved in the biosynthesis and hydrolysis of the endocannabinoid 2-arachidonoyl-glycerol and its congeners

Principal investigatorNSERC2021Discovery Grants Program - Individual

Principal investigators: Flamand, Nicolas

$168,000

Understanding the pathogenesis of COVID-19

Co-investigatorCIHR2020Operating Grant: COVID-19 - Transmission dynamics/animal host/modeling

Principal investigators: Flamand, Louis

Keywords: Cytokines; Inflammation; Leukocytes; Lipid Mediators; Lungs; Macrophages; Novel Coronavirus; Platelets

COVID-19 trilogy: ARDS, inflammation and coagulopathy.

Co-investigatorCIHR2020Operating Grant: COVID-19 Rapid Research Funding Opportunity - Therapeutics

Principal investigators: Flamand, Louis

Keywords: Anti-Thrombin Agents; Antibody Enhancement Of Disease; Covid-19; Cytokines; Fc Receptor; Inflammation; Lipid Mediators Of Inflammation; Pathogenesis; Platelets; Sars-Cov-2

$226,625

Inhibition des fonctions leucocytaires par les métabolites du leucotriène B4 : importance dans la défense de l'hôte et la fibrose kystique.

SupervisorCIHR2017Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Archambault, Anne-Sophie

Keywords: Défense De L'Hôte; Fibrose Kystique; Infections Pulmonaires; Inflammation; Leucocytes; Leucotriènes; Lipides Bioactifs; Macrophages; Monocytes; Neutrophiles

$105,000

The role of autotaxin and lysophosphatidic acid in the development of calcific aortic valve disease

Co-investigatorCIHR2016Project Grant

Principal investigators: Mathieu, Patrick

Keywords: Animal Model; Cell Culture; Gene Expression; Microscopy; Molecular Biology; Tissue Analyses; Translational Investigations

$707,164

Régulation des fonctions leucocytaires par les endocannabinoïdes et leurs métabolites

SupervisorCIHR2015Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Turcotte, Caroline

Keywords: Endocannabinoïdes; Immunorésolvants; Inflammation; Leucocytes; Lipases; Lipides Bioactifs; Macrophages; Neutrophiles; Pneumologie; Prostaglandines

$105,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2021

Subject: Prospective PhD student: Bioactive Lipid Dear Professor Flamand, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Brain DHA increases in APOE3, but not in APOE4 mice, despite robust brain EPA increase during LPC n-3 supplementation in both genotypes." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Cellular and molecular mechanisms involved in the biosynthesis and hydrolysis of the endocannabinoid 2-arachidonoyl-glycerol and its congeners" (2021), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

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Nicolas Flamand

Research

Latest papers

Latest funding

Brain DHA increases in APOE3, but not in APOE4 mice, despite robust brain EPA increase during LPC n-3 supplementation in both genotypes.

Alteration of epidermal lipid metabolism by 2-linoleoylglycerol in a 3D skin model.

Fattening Physiology in a Long-Distance Migrant: Interplay between Baseline Corticosterone, Diet, and the Endocannabinoidome.

Biosynthesis and analytics of specialized pro-resolving mediators: facts and faults.

Intestinal colonization of germ-free mice with indole-producing E. coli modulates the central and peripheral endocannabinoidome.

Linoleic acid concentration at the air-liquid interface is key for optimal incorporation into skin model lipidome.

Longitudinal changes in endocannabinoidome and dietary lipid profile in severe obesity: impact of sleeve gastrectomy.

Seal and fish oils partially counteract inflammation and modulate endocannabinoidome lipid and oxylipin alterations in DSS-induced colitis.

Circadian disruption elicits sex-specific gut microbiota, endocannabinoidome, and lipid mediator responses.

Impact of Oral Cannabinoids on the Endocannabinoidome and Gut Microbiome in People with HIV on Antiretroviral Therapy (CTN PT028 Pilot Clinical Trial).

Cellular and molecular mechanisms involved in the biosynthesis and hydrolysis of the endocannabinoid 2-arachidonoyl-glycerol and its congeners

Frequent collaborators

Vincenzo Di Marzo

Alain Veilleux

Roxane Pouliot

David Marsolais

Louis Flamand

Jamila Chakir

Laurent Biertho

Arnaud Droit

Marc Pouliot

Mohammad-Ali Jenabian

Julie Fradette

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Gabriella Gobbi

Marie-Renée Blanchet

Catherine Laprise

Naguib Mechawar

Shari Margolese

Frederic Raymond

Benoit Laurent

Caroline Menard

Sylvie Breton

Vicky Drapeau

Flavie Lavoie-Cardinal

Madeleine Durand

Julie Robitaille

Madeleine Durand

Jean-Pierre Routy

Olivier Barbier

Marc Prentki

Mathieu Laplante

Nahum Sonenberg

Denis Soulet

Louis Schmidt

Emile Levy