Jorge Soliz, Université Laval

Research

Brainstem Sex Dimorphism Breathing Dysfunction Gaba Hypothalamo-Pituitary-Adrenal Axis Mitochondria Neonatal Tress Nucleus Tractus Solitarii (Nts)

Latest papers

GATOR1 signaling defects promote astrocytic metabolic rewiring and excitatory neurotransmitter cycling.
EMBO reports · 2026
High altitude limits the biogeography of common rats but not house mice.
Scientific reports · 2026
The high-altitude baby: Neonatal development and survival in hypoxic environments.
Respiratory physiology & neurobiology · 2026 · senior author

All 57 publications

Latest funding

Hyperactive mitochondria: a novel mechanism to explain early life stress-related sleep apneas in adult mice
CIHR · 2022 · Nominated PI
$703,800
Estradiol receptor alpha mediates sex-specific responses in an animal model of sleep apnea.
CIHR · 2018 · Co-investigator
$634,950
Targeting sex mitochondrial asymmetry to elucidate sex-specific consequences of intermittent hypoxia in newborns
CIHR · 2017 · Nominated PI
$150,000

All 6 grants and awards

57 publications.

01

GATOR1 signaling defects promote astrocytic metabolic rewiring and excitatory neurotransmitter cycling.

Hadj-Aissa I, Muller M, Soliz J, Sephton CF, Dutchak PA

EMBO reports2026

DOI: 10.1038/s44319-026-00846-w PMID: 42399454

02

High altitude limits the biogeography of common rats but not house mice.

Arias-Reyes C, Carvajal-Rodriguez F, Soliz J, Joseph V

Scientific reports2026

DOI: 10.1038/s41598-026-53527-y PMID: 42162130

03

The high-altitude baby: Neonatal development and survival in hypoxic environments.

Soliz A, Soliz J

Respiratory physiology & neurobiology2026Senior author

DOI: 10.1016/j.resp.2026.104609 PMID: 42264118

04

Clinical exposure thresholds associated with retinopathy of prematurity in preterm infants born at high altitude.

Guillén MV, Copa MWQ, García DV, Arias-Reyes C, Soliz J

Respiratory physiology & neurobiology2026Senior author

DOI: 10.1016/j.resp.2026.104561 PMID: 41794203

05

Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity.

Marcadet L, Pelaez MC, Desmeules A, Serrano J, Cheng Z, Khademullah CS, Parham E, Kennedy J, Troakes C, Vance C, Soliz J, Durham HD, Li L, Dutchak PA, Sephton CF

Brain : a journal of neurology2026

DOI: 10.1093/brain/awaf328 PMID: 40971894

06

Methacholine hyperresponsiveness in mice with house dust mite-induced lung inflammation is not associated with excessive airway constriction ex vivo.

Rojas-Ruiz A, Boucher M, Henry C, Gélinas L, Packwood R, Graham P, Soliz J, Bossé Y

Experimental physiology2025

DOI: 10.1113/ep092522 PMID: 40153804

07

High altitude induces a shift from complex I to complex II in the brain mitochondria of newborn and adult mice.

Demarest M, Aliaga-Raduan F, Arias-Reyes C, Gonzales M, Schneider Gasser EM, Soliz J, Joseph V

The Journal of experimental biology2025

DOI: 10.1242/jeb.250422 PMID: 40692438

08

Lung Tissue Compliance Interacts with Smooth Muscle and Drives Hyperresponsiveness in Mice with Experimental Asthma.

Hecht S, Rojas-Ruiz A, Boucher M, Henry C, Soliz J, Bossé Y

Lung2025

DOI: 10.1007/s00408-025-00840-4 PMID: 40730919

09

Low and sustained doses of erythropoietin prevent preterm infants from intraventricular hemorrhage.

Arias Fernández DA, Romero Diaz HA, Figueroa Garnica AD, Iturri-Soliz P, Arias-Reyes C, Schneider Gasser EM, Soliz J

Respiratory physiology & neurobiology2025Senior author

DOI: 10.1016/j.resp.2024.104363 PMID: 39510295

10

Lung Volumes in a Mouse Model of Pulmonary Allergic Inflammation.

Rojas-Ruiz A, Boucher M, Henry C, Packwood R, Soliz J, Bossé Y

Lung2024

DOI: 10.1007/s00408-024-00730-1 PMID: 39020115

Hyperactive mitochondria: a novel mechanism to explain early life stress-related sleep apneas in adult mice

Nominated PICIHR2022Project Grant

Principal investigators: Soliz, Jorge

Keywords: Brainstem; Breathing Dysfunction; Gaba; Hypothalamo-Pituitary-Adrenal Axis; Mitochondria; Neonatal Tress; Nucleus Tractus Solitarii (Nts); Paraventricular Nucleus Of The Hypothalamus (Pvh); Sex Dimorphism; Sleep Apnea

$703,800

Estradiol receptor alpha mediates sex-specific responses in an animal model of sleep apnea.

Co-investigatorCIHR2018Project Grant

Principal investigators: Joseph, Vincent

Keywords: Adipose Tissue; Cre-Lox Mice; Endothelium; Estradiol; Estradiol Receptor; Intermittent Hypoxia; Menopause; Sleep Apnea

$634,950

Targeting sex mitochondrial asymmetry to elucidate sex-specific consequences of intermittent hypoxia in newborns

Nominated PICIHR2017Catalyst Grant: Sex as a Variable in Biomedical Research

Principal investigators: Soliz, Jorge

Keywords: Apnea Of Prematurity; Cardiolipin; Inflammation; Intermittent Hypoxia; Microglia; Mitochondrial Dysfunction; Neonatal Brain Development; Oxidative Stress; Premature Infants; Sex Dimorphism Preterm Infants

$150,000

Adaptation and acclimatization to altitude in newborn rodents.

Co-investigatorNSERC2014Discovery Grants Program - Group

Principal investigators: Joseph, Vincent

$155,000

Electrophysiology set up for respiratory neurobiology

Co-investigatorNSERC2013Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Kinkead, Richard

$132,116

Cerebral erythropoietin as a novel mechanism to explain sex-specific respiratory depression in neonates

Nominated PICIHR2013Operating Grant

Principal investigators: Soliz, Jorge

Keywords: Apnea; Brainstem; Erythropoietin; Hypoxia; Masculinization; Neonates; Respiratory Depression; Sex Dimorphism; Sids; Testosterone

$274,827

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Pédiatrie
Medicine
Chemistry

Co-authors at Université Laval, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Vincent Joseph

Pédiatrie

20 shared papers, latest 2026

Richard Kinkead

Pédiatrie

6 shared papers, latest 2022

David Marsolais

Medicine

2 shared papers, latest 2022

Liang Li

Chemistry

1 shared papers, latest 2026

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2022

Subject: Prospective PhD student: Brainstem Dear Professor Soliz, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "GATOR1 signaling defects promote astrocytic metabolic rewiring and excitatory neurotransmitter cycling." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Hyperactive mitochondria: a novel mechanism to explain early life stress-related sleep apneas in adult mice" (2022), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]