Patrick Desrosiers, Université Laval

Research

Stochastic processes biological neural networks artificial recurrent neural networks synaptic plasticity neuromodulation biologically inspired learning rules emergent phenomena dynamical resilience

Latest papers

Excessive inhibition in the medial prefrontal cortex contributes to cognitive susceptibility in aging.
Neurobiology of disease · 2026
Chronic optogenetic activation of hippocampal CA1 neurons triggers Alzheimer's disease-like proteomic remodeling.
iScience · 2025
Structural and genetic determinants of zebrafish functional brain networks.
Science advances · 2025

All 15 publications

Latest funding

Intertwined dynamics of neurons and synapses in large neural networks
NSERC · 2024 · Principal investigator
$41,000
Mapping scientific consensus in the age of misinformation
SSHRC · 2020 · Co-investigator
$247,500
Large neuronal networks: from structure to function, and back
NSERC · 2019 · Principal investigator
$140,000

All 3 grants and awards

15 publications.

01

Excessive inhibition in the medial prefrontal cortex contributes to cognitive susceptibility in aging.

Keramidis I, Desrosiers P, Verreault AA, Sansonetti R, Hazrati R, Godin AG, De Koninck Y

Neurobiology of disease2026

DOI: 10.1016/j.nbd.2026.107385 PMID: 41962851

02

Chronic optogenetic activation of hippocampal CA1 neurons triggers Alzheimer's disease-like proteomic remodeling.

Keramidis I, Samiotaki M, Sansonetti R, Alonso J, Desrosiers P, Papanikolopoulou K, De Koninck Y

iScience2025

DOI: 10.1016/j.isci.2025.113454 PMID: 41169497

03

Structural and genetic determinants of zebrafish functional brain networks.

Légaré A, Lemieux M, Boily V, Poulin S, Légaré A, Desrosiers P, De Koninck P

Science advances2025

DOI: 10.1126/sciadv.adv7576 PMID: 40644546

04

Firing rate distributions in plastic networks of spiking neurons.

Vegué M, Allard A, Desrosiers P

Network neuroscience (Cambridge, Mass.)2025Senior author

DOI: 10.1162/netn_a_00442 PMID: 40161997

05

Duality between predictability and reconstructability in complex systems.

Murphy C, Thibeault V, Allard A, Desrosiers P

Nature communications2024Senior author

DOI: 10.1038/s41467-024-48020-x PMID: 38796449

06

The Determining Role of Covariances in Large Networks of Stochastic Neurons.

Painchaud V, Desrosiers P, Doyon N

Neural computation2024

DOI: 10.1162/neco_a_01656 PMID: 38657971

07

Author Correction: Predicting cognitive decline in a low-dimensional representation of brain morphology.

Lamontagne-Caron R, Desrosiers P, Potvin O, Doyon N, Duchesne S

Scientific reports2023

DOI: 10.1038/s41598-023-46972-6 PMID: 37978214

08

Predicting cognitive decline in a low-dimensional representation of brain morphology.

Lamontagne-Caron R, Desrosiers P, Potvin O, Doyon N, Duchesne S

Scientific reports2023

DOI: 10.1038/s41598-023-43063-4 PMID: 37798311

09

Zebrafish brain atlases: a collective effort for a tiny vertebrate brain.

Légaré A, Lemieux M, Desrosiers P, De Koninck P

Neurophotonics2023

DOI: 10.1117/1.nph.10.4.044409 PMID: 37786400

10

Dimension reduction of dynamics on modular and heterogeneous directed networks.

Vegué M, Thibeault V, Desrosiers P, Allard A

PNAS nexus2023

DOI: 10.1093/pnasnexus/pgad150 PMID: 37215634

Intertwined dynamics of neurons and synapses in large neural networks

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: Desrosiers, Patrick

Keywords: biological neural networks; artificial recurrent neural networks; synaptic plasticity; neuromodulation; biologically inspired learning rules; emergent phenomena; dynamical resilience; random matrices; stochastic processes; animal behavior

$41,000

Mapping scientific consensus in the age of misinformation

Co-investigatorSSHRC2020New Frontiers in Research Fund - Exploration

Principal investigators: Lariviere, Vincent

Keywords: science journalism science mapping scientific consensus misinformation scholarly communication complex systems science of science sociology of science information flows

$247,500

Large neuronal networks: from structure to function, and back

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Desrosiers, Patrick

Keywords: Causality and Connectivity; Computer simulations; Dynamics; Information and Entropy; Mouse; Networks; Neurons; Resilience; Stochastic processes; Zebrafish

$140,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Physique, génie physique et optique
Département de Physique, de Génie Physique et d'Optique
Biochimie et microbiologie
Radiology and Nuclear Medicine
Other

Co-authors at Université Laval, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Antoine Allard

Département de Physique, de Génie Physique et d'Optique

4 shared papers, latest 2025

Paul De Koninck

Biochimie et microbiologie

3 shared papers, latest 2025

Yves De Koninck

Faculty

3 shared papers, latest 2026

Simon Duchesne

Radiology and Nuclear Medicine

2 shared papers, latest 2023

Feng Wang

Faculty

1 shared papers, latest 2018

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2024

Subject: Prospective PhD student: Stochastic processes Dear Professor Desrosiers, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Excessive inhibition in the medial prefrontal cortex contributes to cognitive susceptibility in aging." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Intertwined dynamics of neurons and synapses in large neural networks" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]