Faculty profile

Ryan Zarychanski

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ProfessorDepartment of Internal MedicineUniversity of Manitoba

Ryan Zarychanski

Professor

Department of Internal Medicine

Max Rady College of Medicine

University of Manitoba

Winnipeg, Manitoba, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
74 publications in the last five years, latest in 2026.
Senior (last) author on 16 recent papers, a sign of leading a research group.
Principal investigator on 28 research grants (28 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

196

Publications

8,889

Citations

300

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Manitoba profile.

Randomized trials, Bayesian adaptive platform trials, Cluster trials Risk-adapted consent Sepsis anticoagulation

Latest papers

Influence of multiple trauma on the effect of transfusion strategies in patients with traumatic brain injury: a sub-study of the HEMOTION trial
Intensive Care Medicine · 2026
Informed Consent in an International Trial of Stress Ulcer Prophylaxis: Patterns and Predictors.
Critical Care Medicine · 2026
The evolving role of heparin in sepsis: therapeutic potential in the age of immunothrombosis
Journal of Thrombosis and Haemostasis · 2026

All 196 publications

Latest funding

Enabling Bayesian Clinical Trials: Improving the use of Bayesian methods in randomised clinical trials of efficacy and effectiveness
CIHR · 2026 · Co-investigator
$1,143,676
The effect of retrograde autologous priming on transfusion requirements after cardiac surgery (TheRAPy): a multiple period cluster-randomized crossover trial
CIHR · 2026 · Co-investigator
$2,008,736
Evidence Synthesis Network for Canada to Support Pandemic Planning and Response
CIHR · 2025 · Co-investigator
$2,000,000

All 88 grants and awards

From the 150 most recent of 196 publications.

Influence of multiple trauma on the effect of transfusion strategies in patients with traumatic brain injury: a sub-study of the HEMOTION trial

Bouras M, Lauzier F, Fergusson DA, Neveu X, Clayton L, Patton M-P, Costerousse O, English SW, Docherty A, Malbouisson LMS

Intensive Care Medicine20262 citations

DOI: 10.1007/s00134-025-08290-5

Informed Consent in an International Trial of Stress Ulcer Prophylaxis: Patterns and Predictors.

Mehta S, Burns KEA, Zytaruk N, Heels-Ansdell D, Hand L, Clarke F, Hardie M, Lad V, Geagea A, Binnie A

Critical Care Medicine20261 citations

DOI: 10.1097/ccm.0000000000007314

The evolving role of heparin in sepsis: therapeutic potential in the age of immunothrombosis

Liaw PC, Zarychanski R, Lawler PR, Lother SA, Mendelson AA

Journal of Thrombosis and Haemostasis2026

DOI: 10.1016/j.jtha.2026.06.017

Excitatory amino acid inhibitors in adults with acute moderate to severe traumatic brain injury: a systematic review and meta-analysis.

Bouras M, Costerousse O, Verret M, O'connor S, Zarychanski R, Gagnon MA, Torkomyan TH, Ouellet A, Lauzier F, English S, Moore L, Turgeon AF

BMJ open2026

DOI: 10.1136/bmjopen-2025-108337 PMID: 41856577

Intermediate dose heparin thromboprophylaxis among critically ill patients with COVID-19: a randomized clinical trial.

Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia (REMAP-CAP) Investigators, Bradbury CA, McVerry BJ, Lawler PR, Angus DC, Annane D, Arabi YM, Aryal D, Au C, Beane A, Berry SM, Berry LR, Best-Lane J, Bihari S, Bonten M, Brunkhorst F, Burrell A, Buxton M, Carrier M, Cecconi M, Cheng AC, Cove M, Derde LPG, Detry MA, Estcourt LJ, Fergusson DA, Fitzgerald M, Fowler RA, Goligher EC, Green C, Haniffa R, Harrison DA, Hays LMC, Higgins AM, Hills T, Horvat CM, Huang DT, Hunt BJ, Ichihara N, Jayakumar D, Keattch S, Kumar A, Laffan MA, Lamontagne F, Leeper CM, Lewis RJ, Lorenzi E, Lother SA, Marshall JC, McArthur CJ, McAuley DF, McGlothlin A, McGuinness SP, McQuilten ZK, Middeldorp S, Morpeth S, Mouncey PR, Murthy S, Neal MD, Nichol AD, Parke RL, Parker JC, Peters S, Reyes LF, Rowan K, Saito H, Santos M, Saunders CT, Schutgens REG, Seymour CW, Hari MS, Singh V, Stanworth SJ, Turgeon AF, Turner AM, van de Veerdonk FL, Gordon AC, Webb SA, Zarychanski R

Journal of thrombosis and haemostasis : JTH2026

DOI: 10.1016/j.jtha.2026.03.006 PMID: 41895526

Ivermectin for Critically and Noncritically Ill Hospitalized Patients With COVID-19: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP).

Hashmi M, Haniffa R, Jayakumar D, Beane A, Lorenzi E, Berry LR, Nasir Khoso M, Ain Khan Q, Kumar A, Altaf Kidwai A, Hills TE, Annane D, Aryal D, Au C, Baillie K, Beasley R, Best-Lane J, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Cecconi M, Cheng AC, Cove ME, de Jong M, Detry MA, Duffy E, Estcourt LJ, Fitzgerald M, Fowler R, Goossens H, Green C, Hays LMC, Higgins AM, Huang DT, Ichihara N, Koirala S, Lamontagne F, Lawler PR, Lewis RJ, Litton E, Mahon N, Marshall JC, McAuley DF, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Morpeth S, Netea M, Orr K, Parke RL, Parker JC, Patanwala A, Peters S, Reyes LF, Rowan KM, Saito H, Saunders CT, Santos M, Seymour CW, Shankar-Hari M, Singh V, Slater M, Tambyah PA, Tong SYC, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Zarychanski R, McArthur CJ, Angus DC, Berry SM, Gordon AC, Derde LPG, Webb SA, Murthy S, Arabi Y, Nichol AD, and the Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP) Investigators

Critical care medicine2026

DOI: 10.1097/ccm.0000000000007134 PMID: 42101205

Hemophagocytic Lymphohistiocytosis Secondary to Disseminated Bacillus Calmette-Guérin (BCG): A Steroid-Sparing Strategy in a Patient Awaiting Cardiac Surgery-A Case Report.

Quinlan K, MacDonald T, Wuerz TC, Zarychanski R

Case reports in hematology2026Senior author

DOI: 10.1155/crh/5761690 PMID: 41668968

Timing, Translation, and Preparedness: Lessons Learned From COVID-19 Anticoagulation in Noncritically Ill Hospitalized Patients.

Tritschler T, Fuster V, Lawler PR, Farkouh ME, Marx CE, Neal MD, Sholzberg M, Spyropoulos AC, Tong SYC, Muñoz-Rivas N, Blondon M, Berger JS, Bikdeli B, Cattaneo M, Cushman M, Goldin M, Goligher EC, Hochman JS, Jüni P, McQuilten ZK, Morici N, Sadeghipour P, Venkatesh B, Zuily S, Amstutz A, Aujesky D, Carrier M, Hofstetter RV, Murthy S, Rodger M, Skeith L, Veroniki AA, Hutton B, Zarychanski R, Stone GW, Le Gal G, Anticoagulation in COVID-19 Investigators

Journal of the American College of Cardiology2026

DOI: 10.1016/j.jacc.2026.05.028 PMID: 42523015

Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage.

Sperry JL, Guyette FX, Cotton BA, Luther JF, Utarnachitt RB, Kutcher ME, Daley BJ, Peetz AB, Patel MB, Goodman MD, Claridge JA, Patel N, Harbrecht BG, Hashmi ZG, Zarychanski R, Neal MD, Yazer MH, Martin-Gill C, Vincent LE, Harner AM, Meyer DE, Latimer AJ, Robinson BR, McKnight CL, Hinckley WR, Miller KR, Jansen JO, Martin D, Fox EE, Rosario-Rivera BL, Wisniewski SR, TOWAR Study Group

The New England journal of medicine2026

DOI: 10.1056/nejmoa2602167 PMID: 42150044

Association between neurofilament light chain concentrations and outcomes in patients with moderate to severe traumatic brain injury: a systematic review and meta-analysis.

Bouras M, Pageau M, Gagnon MA, Costerousse O, Demers K, Grenier-Gagnon A, Isaac CJ, Torkomyan TH, Lauzier F, Zarychanski R, Francoeur CL, Gerges P, Abiala G, Moore L, English SW, Turgeon AF, Canadian Traumatic Brain Injury Research Consortium

Critical care (London, England)2026

DOI: 10.1186/s13054-026-06036-3 PMID: 42083049

Profile data last refreshed on September 27, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Ryan Zarychanski

Research

Latest papers

Latest funding

Influence of multiple trauma on the effect of transfusion strategies in patients with traumatic brain injury: a sub-study of the HEMOTION trial

Informed Consent in an International Trial of Stress Ulcer Prophylaxis: Patterns and Predictors.

The evolving role of heparin in sepsis: therapeutic potential in the age of immunothrombosis

Excitatory amino acid inhibitors in adults with acute moderate to severe traumatic brain injury: a systematic review and meta-analysis.

Intermediate dose heparin thromboprophylaxis among critically ill patients with COVID-19: a randomized clinical trial.

Ivermectin for Critically and Noncritically Ill Hospitalized Patients With COVID-19: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP).

Hemophagocytic Lymphohistiocytosis Secondary to Disseminated Bacillus Calmette-Gu&#xe9;rin (BCG): A Steroid-Sparing Strategy in a Patient Awaiting Cardiac Surgery-A Case Report.

Timing, Translation, and Preparedness: Lessons Learned From COVID-19 Anticoagulation in Noncritically Ill Hospitalized Patients.

Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage.

Association between neurofilament light chain concentrations and outcomes in patients with moderate to severe traumatic brain injury: a systematic review and meta-analysis.

Frequent collaborators

Anand Kumar

Srinivas Murthy

Deborah Cook

Lynne Moore

Emily Rimmer

Francois Lamontagne

Jennifer Tsang

Gloria Vazquez-Grande

Marc Carrier

Lauralyn McIntyre

Bram Rochwerg

Ian Ball

Dean Fergusson

John Marshall

Alan Tinmouth

Maureen Meade

Diane Heels-Ansdell

Shane English

Timothy A Karachi

Donald Arnold

Karen Burns

Donald Griesdale

Erick Duan

John Muscedere

Nick Daneman

François Lauzier

Alison Fox-Robichaud

Murdoch Leeies

Ahmed Abou-Setta

Peter Dodek

Michael Verret

Deborah Siegal

Emilie Belley-Cote

Mark Crowther

Joanna Dionne

Gordon Guyatt

Na Li

Draga Jichici

Mark Soth

Nancy Heddle

Hemophagocytic Lymphohistiocytosis Secondary to Disseminated Bacillus Calmette-Guérin (BCG): A Steroid-Sparing Strategy in a Patient Awaiting Cardiac Surgery-A Case Report.