Christos Boutopoulos

Research

Biomaterials Cornea Drop-On-Demand Bioprinting In-Vivo Bioprinting Laser-Assisted Bioprinting Ophthalmology Optical Coherence Tomogrpahy Tissue Engineering

Latest papers

Collagen Analogs Promote Tissue Regeneration in HSV-1-Infected Corneas in Animal Models.
Journal of functional biomaterials · 2025
Biosynthetic Collagen-Analog Hydrogels Stimulate Endogenous Regrowth of Rabbit Corneas: A Pilot Study.
Veterinary sciences · 2025
Development and ex-vivo validation of 36G polyimide cannulas integrating a guiding miniaturized OCT probe for robotic assisted subretinal injections.
Biomedical optics express · 2022 · senior author

All 9 publications

Latest funding

Harnessing Laser Bioprinting and Robotics for In-Situ Repair of Corneal Wounds with Regeneration Biomaterials
CIHR · 2024 · Nominated PI
$795,600
A histology suite for visualizing cell distribution in tissues
NSERC · 2024 · Co-investigator
$110,438
Nanophotonics silencing of nociceptors-ILC2 crosstalk in AD-mediated skin inflammation
CIHR · 2022 · Supervisor
$90,000

All 10 grants and awards

9 publications.

01

Collagen Analogs Promote Tissue Regeneration in HSV-1-Infected Corneas in Animal Models.

Buznyk O, Goodarzi H, Gómez Laguna J, Reddy J, Liszka A, Edin E, Boutopoulos C, Chodosh J, Islam MM, Griffith M

Journal of functional biomaterials2025

DOI: 10.3390/jfb16100377 PMID: 41149723

02

Biosynthetic Collagen-Analog Hydrogels Stimulate Endogenous Regrowth of Rabbit Corneas: A Pilot Study.

Timmerman I, Robert MC, Vergneau-Grosset C, Juette T, Benito J, Garbin M, Zamani-Roudbaraki M, Moradi M, Goodarzi H, Boutopoulos C, Benoit-Biancamano MO, Griffith M, Vanore M

Veterinary sciences2025

DOI: 10.3390/vetsci12080785 PMID: 40872735

03

Development and ex-vivo validation of 36G polyimide cannulas integrating a guiding miniaturized OCT probe for robotic assisted subretinal injections.

Abid A, Duval R, Boutopoulos C

Biomedical optics express2022Senior author

DOI: 10.1364/boe.448471 PMID: 35284163

04

A Smart Vitrector Equipped by a Fiber-Based OCT Sensor Mitigates Intentional Attempts at Creating Iatrogenic Retinal Breaks During Vitrectomy in Pigs.

Abid A, Duval R, Rezende F, Boutopoulos C

Translational vision science & technology2021Senior author

DOI: 10.1167/tvst.10.13.19 PMID: 34767622

05

Drop-on-demand cell bioprinting via Laser Induced Side Transfer (LIST).

Ebrahimi Orimi H, Hosseini Kolkooh SS, Hooker E, Narayanswamy S, Larrivée B, Boutopoulos C

Scientific reports2020Senior author

DOI: 10.1038/s41598-020-66565-x PMID: 32546799

06

Etching-enabled extreme miniaturization of graded-index fiber-based optical coherence tomography probes.

Abid A, Mittal S, Boutopoulos C

Journal of biomedical optics2019Senior author

DOI: 10.1117/1.jbo.25.3.032006 PMID: 31707773

07

A needle-like optofluidic probe enables targeted intracellular delivery by confining light-nanoparticle interaction on single cell.

Doppenberg A, Meunier M, Boutopoulos C

Nanoscale2018Senior author

DOI: 10.1039/c8nr03895c PMID: 30457139

08

Multiscale modeling of plasmonic enhanced energy transfer and cavitation around laser-excited nanoparticles.

Dagallier A, Boulais E, Boutopoulos C, Lachaine R, Meunier M

Nanoscale2017

DOI: 10.1039/c6nr08773f PMID: 28182187

09

Cell-specific optoporation with near-infrared ultrafast laser and functionalized gold nanoparticles.

Bergeron E, Boutopoulos C, Martel R, Torres A, Rodriguez C, Niskanen J, Lebrun JJ, Winnik FM, Sapieha P, Meunier M

Nanoscale2015

DOI: 10.1039/c5nr05650k PMID: 26459958

Harnessing Laser Bioprinting and Robotics for In-Situ Repair of Corneal Wounds with Regeneration Biomaterials

Nominated PICIHR2024Project Grant

Principal investigators: Boutopoulos, Christos; Griffith, May C

Keywords: Biomaterials; Cornea; Drop-On-Demand Bioprinting; In-Vivo Bioprinting; Laser-Assisted Bioprinting; Ophthalmology; Optical Coherence Tomogrpahy; Tissue Engineering

$795,600

A histology suite for visualizing cell distribution in tissues

Co-investigatorNSERC2024Research Tools and Instruments

Principal investigators: Lesage, Sylvie

Keywords: Cellular positioning; Fluorecent microscopy; Histology; Microscopy; Tissue sections

$110,438

Nanophotonics silencing of nociceptors-ILC2 crosstalk in AD-mediated skin inflammation

SupervisorCIHR2022CIHR Fellowship

Principal investigators: Roversi, Katiane

Keywords: Atopic Dermatitis; Gold Nanoparticles; Nanophotonics; Neuroimmune Diseases; Nociceptors; Pain; Trpv1 Channel

$90,000

An OCT-controlled system for precise and reproducible subretinal drug injection in mice

Nominated PICIHR2021Project Grant

Principal investigators: Boutopoulos, Christos

Keywords: Cell Therapy; Drug Delivery; Fiber Probes; Gene Therapy; Optical Coherence Tomography; Retina; Retina Degeneration; Subretinal Injection

$179,775

Bringing a Liquid Cornea for treating corneal blindness into the clinic

Co-investigatorNSERC2020Collaborative Health Research Projects

Principal investigators: Griffith, May

$321,089

A system for automated high-content screening and laser manipulation of single cells.

Co-investigatorNSERC2019Research Tools and Instruments

Principal investigators: Costantino, Santiago

$127,074

The Liquid Cornea as an alternative to corneal transplantation: Pathway to Clinical trials

Principal investigatorCIHR2019Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Griffith, May C; Munger, Réjean J; Boutopoulos, Christos; Robert, Marie-Claude

Keywords: Anti-Scarring; Biomaterials; Clinical Translation; Collagen-Like Peptides; Cornea; Delivery System; Glp; Mini-Pigs; Optical Evaluation; Pre-Clinical

$306,789

Nanophotonics-controlled silencing of nociceptor neurons

Principal investigatorSSHRC2019New Frontiers in Research Fund - Exploration

Principal investigators: Boutopoulos, Christos

Keywords: Nanophotonics; Sensory neurons; Targeted drug delivery; Gold nanoparticle; TRPV1; QX-314; Neurogenic inflammation

$273,175

Multiscale Modeling and Applications of Three-Dimensional (3D) Laser Bio-printing

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Boutopoulos, Christos

$198,000

Multiscale Modeling and Applications of Three-Dimensional (3D) Laser Bio-printing

Principal investigatorNSERC2018Discovery Launch Supplement

Principal investigators: Boutopoulos, Christos

$12,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Ophthalmology
Engineering Physics
Pharmacologie - Physiologie
Medicine

Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Michel Meunier

Engineering Physics

3 shared papers, latest 2018

May Griffith

Pharmacologie - Physiologie

2 shared papers, latest 2025

Marie-Claude Robert

Ophthalmology

1 shared papers, latest 2025

Przemyslaw Sapieha

Engineering Physics

1 shared papers, latest 2015

Przemyslaw Sapieha

Ophthalmology

1 shared papers, latest 2015

Jean-Jacques Lebrun

Medicine

1 shared papers, latest 2015

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2024

Subject: Prospective PhD student: Biomaterials Dear Professor Boutopoulos, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Collagen Analogs Promote Tissue Regeneration in HSV-1-Infected Corneas in Animal Models." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Harnessing Laser Bioprinting and Robotics for In-Situ Repair of Corneal Wounds with Regeneration Biomaterials" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]