This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
The Neurexin1β Histidine-Rich Domain Is Involved in Excitatory Presynaptic Organization and Short-Term Plasticity.
eNeuro · 2026 · senior author
Alpha-neurexins in health and disease.
Frontiers in molecular neuroscience · 2025 · senior author
Rare missense variants of the leukocyte common antigen related receptor (LAR) display reduced activity in transcellular adhesion and synapse formation.
Research square · 2025
Latest funding
- $1,071,000
Cell-adhesion mechanisms of inhibitory synapse specificity and their dysfunction in neuropsychiatric disorders
CIHR · 2023 · Nominated PI
- $872,100
Novel therapeutic molecular targets for amyloid-beta pathology in Alzheimer's disease
CIHR · 2018 · Nominated PI
- $217,000
Trans-synaptic coupling of phosphorylation signalling for central synapse development
NSERC · 2017 · Principal investigator
15 publications.
The Neurexin1β Histidine-Rich Domain Is Involved in Excitatory Presynaptic Organization and Short-Term Plasticity.
Feller B, Inagaki M, Wang M, Sivak A, Chofflet N, Takahashi H
Alpha-neurexins in health and disease.
Chofflet N, Wang M, Chofflet M, Takahashi H
Rare missense variants of the leukocyte common antigen related receptor (LAR) display reduced activity in transcellular adhesion and synapse formation.
Kaas M, Chofflet N, Bicer D, Skeldal S, Duan J, Feller B, Vilstrup J, Groth R, Sivagurunathan S, Dashti H, Pedersen JS, Werge T, Børglum AD, Cimini BA, Jones TR, Claussnitzer M, Madsen P, Takahashi H, Demontis D, Thirup S, Glerup S
Rare missense variants of the leukocyte common antigen related receptor (LAR) display reduced activity in transcellular adhesion and synapse formation.
Kaas M, Chofflet N, Bicer D, Skeldal S, Duan J, Feller B, Vilstrup J, Groth R, Sivagurunathan S, Dashti H, Pedersen JS, Werge T, Børglum AD, Cimini BA, Jones TR, Claussnitzer M, Madsen P, Takahashi H, Demontis D, Thirup S, Glerup S
The TrkC-PTPσ complex governs synapse maturation and anxiogenic avoidance via synaptic protein phosphorylation.
Khaled H, Ghasemi Z, Inagaki M, Patel K, Naito Y, Feller B, Yi N, Bourojeni FB, Lee AK, Chofflet N, Kania A, Kosako H, Tachikawa M, Connor S, Takahashi H
Molecular mechanism of contactin 2 homophilic interaction.
Fan S, Liu J, Chofflet N, Bailey AO, Russell WK, Zhang Z, Takahashi H, Ren G, Rudenko G
Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.
Chofflet N, Naito Y, Pastore AJ, Padmanabhan N, Nguyen PT, Poitras C, Feller B, Yi N, Van Prooijen J, Khaled H, Coulombe B, Clapcote SJ, Bourgault S, Siddiqui TJ, Rudenko G, Takahashi H
α-Synuclein Preformed Fibrils Bind to β-Neurexins and Impair β-Neurexin-Mediated Presynaptic Organization.
Feller B, Fallon A, Luo W, Nguyen PT, Shlaifer I, Lee AK, Chofflet N, Yi N, Khaled H, Karkout S, Bourgault S, Durcan TM, Takahashi H
Designer molecules of the synaptic organizer MDGA1 reveal 3D conformational control of biological function.
Lee H, Chofflet N, Liu J, Fan S, Lu Z, Resua Rojas M, Penndorf P, Bailey AO, Russell WK, Machius M, Ren G, Takahashi H, Rudenko G
SorCS1 inhibits amyloid-β binding to neurexin and rescues amyloid-β-induced synaptic pathology.
Lee AK, Yi N, Khaled H, Feller B, Takahashi H
Cell-adhesion mechanisms of inhibitory synapse specificity and their dysfunction in neuropsychiatric disorders
Principal investigators: Takahashi, Hideto
Keywords: Cell Adhesion; Molecular And Cellular Neuroscience; Neurobiology; Neuropsychiatric Disorder; Synapse Biology
Novel therapeutic molecular targets for amyloid-beta pathology in Alzheimer's disease
Principal investigators: Takahashi, Hideto
Keywords: Alzheimer'S Disease; Amyloid-Beta Pathology; Cell Adhesion; Molecular And Cellular Neuroscience; Neurobiology; Synapse Biology
Trans-synaptic coupling of phosphorylation signalling for central synapse development
Principal investigators: Takahashi, Hideto
Cell-adhesion mechanisms that control GABAergic synapse development
Principal investigators: Takahashi, Hideto
Keywords: Epilepsy; Excitation And Inhibition Balance; Gabaergic Synapse; Immunofluorescent Imaging; Intracranial Electroencephalogram (Eeg); Knockout Mouse; Neuron Culture; Neuronal Adhesion; Neuropsychiatric Disorder; Synapse Development
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Hideto Takahashi and Steve Bourgault: 2 shared papers
- Artur Kania and Hideto Takahashi: 1 shared paper
- Sciences biologiques
- Other
Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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