Mark Keezer, Université de Montréal

Research

Biomarkers Epilepsy Immune System Tuberous Sclerosis Complex Genetics Intellectual Disability Inflammation Blood Pressure

Latest papers

Transitional objects and objective clinical signs in functional/dissociative seizures and epileptic seizures: A comparative study.
Epilepsy & behavior : E&B · 2026
Optimal approach to standardized documentation in epilepsy clinics: A scoping review.
Epilepsia · 2026
Screening and Management of Depression and Anxiety in People With Epilepsy: A Quality Improvement Study.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2025

All 20 publications

Latest funding

Non-medical cannabis use in people with epilepsy
CIHR · 2026 · Co-investigator
$2,325,010
Mapping Neurological Conditions in Canada: Leveraging A Decade of CLSA Data
CIHR · 2025 · Co-investigator
$70,000
Peripheral and CNS inflammation and injury profiles in children with Tuberous Sclerosis Complex and their association with neurological disability and treatment with mTOR inhibitors: a multicentre, longitudinal study cohort.
CIHR · 2025 · Nominated PI
$1,453,500

All 5 grants and awards

20 publications.

01

Transitional objects and objective clinical signs in functional/dissociative seizures and epileptic seizures: A comparative study.

Robin A, Nguyen L, Husein N, Keezer M, Nguyen DK

Epilepsy & behavior : E&B2026

DOI: 10.1016/j.yebeh.2026.111273 PMID: 42673769

02

Optimal approach to standardized documentation in epilepsy clinics: A scoping review.

Marzoughi S, Kimura M, Joseph B, Zhao A, Lorenzetti DL, Nguyen DK, Keezer M, Josephson CB, Jetté N

Epilepsia2026

DOI: 10.1002/epi.70091 PMID: 41518051

03

Screening and Management of Depression and Anxiety in People With Epilepsy: A Quality Improvement Study.

Injar I, Keezer M, Lapalme-Remis S, Chamelian L, Bou Assi E, Nguyen DK

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques2025

DOI: 10.1017/cjn.2025.10491 PMID: 41367213

04

Cenobamate for Drug-Resistant Epilepsy: Initial Experience from a Single Tertiary Center.

Elsherbini T, Léger V, Bérubé AA, Lapalme-Remis S, Keezer M, Nguyen DK

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques2025

DOI: 10.1017/cjn.2025.10487 PMID: 41340378

05

Reduction of generalized tonic-clonic seizures following vagus nerve stimulation therapy: CORE-VNS Study 24-month follow-up.

Suller Marti A, Verner R, Keezer M, Andrade A, Veilleux M, Myers K, Giannicola G, Nichol K, G Burneo J, CORE‐VNS Registry Group

Epilepsia2025

DOI: 10.1111/epi.18371 PMID: 40167365

06

Preeclampsia and the Long-Term Risk of Developing Neurological Disorders Requiring Hospital Admission.

Auger N, Paradis G, Keezer M, Leduc V, Healy-Profitós J, Lewin A, Maniraho A, Potter BJ

Neuroepidemiology2025

DOI: 10.1159/000543087 PMID: 39667352

07

The implications of frailty in older adults with epilepsy.

Hashmi SA, Sachdeva S, Sindhu U, Tsai C, Bonda K, Keezer M, Zawar I, Punia V

Epilepsia open2024

DOI: 10.1002/epi4.13046 PMID: 39248297

08

Computer-assisted analysis of routine EEG to identify hidden biomarkers of epilepsy: A systematic review.

Lemoine É, Neves Briard J, Rioux B, Gharbi O, Podbielski R, Nauche B, Toffa D, Keezer M, Lesage F, Nguyen DK, Bou Assi E

Computational and structural biotechnology journal2024

DOI: 10.1016/j.csbj.2023.12.006 PMID: 38204455

09

Ultrasound elastography of back muscle biomechanical properties: a systematic review and meta-analysis of current methods.

David M, Devantéry K, Nauche B, Chagnon M, Keezer M, Gaudreault N, Bureau NJ, Cloutier G

Insights into imaging2024

DOI: 10.1186/s13244-024-01785-7 PMID: 39143409

10

Outcomes following surgical interventions for hypothalamic hamartomas: protocol for a systematic review and individual patient data meta-analysis.

Goel K, Niazi F, Chen JS, Hadjinicolaou A, Keezer M, Gallagher A, Fallah A, Weil AG

BMJ open2024

DOI: 10.1136/bmjopen-2023-080870 PMID: 38346878

Non-medical cannabis use in people with epilepsy

Co-investigatorCIHR2026Team Grant: The Canadian Cannabis and Brain Health Consortium

Principal investigators: Nguyen, Dang K; Josephson, Colin B; Jutras-Aswad, Didier

Keywords: Anxiety And Depression; Cannabis Habits And Motivations; Cognitive Functioning; Epilepsy; Mental Health; Neuropsychological Assessments; Non-Medical Cannabis; Psychological Well-Being; Public Health; Quality Of Life

$2,325,010

Mapping Neurological Conditions in Canada: Leveraging A Decade of CLSA Data

Co-investigatorCIHR2025Catalyst Grant: Analysis of CLSA Data - INMHA Mandate

Principal investigators: Wolfson, Christina M

Keywords: Epilepsy; Multiple Sclerosis; Neurological Conditions; Parkinson'S Disease; Traumatic Brain Injury

$70,000

Peripheral and CNS inflammation and injury profiles in children with Tuberous Sclerosis Complex and their association with neurological disability and treatment with mTOR inhibitors: a multicentre, longitudinal study cohort.

Nominated PICIHR2025Project Grant

Principal investigators: Keezer, Mark; House, Andrew A; Larochelle, Catherine; Major, Philippe; Nabavi Nouri, Maryam; Sham, Lauren

Keywords: Biomarkers; Epilepsy; Genetics; Immune System; Intellectual Disability; Tuberous Sclerosis Complex

$1,453,500

Neuroinflammation as a biomarker for epilepsy and neuropsychiatric comorbidities among people with tuberous sclerosis complex: a prospective, multicentre study

Nominated PICIHR2022Project Grant

Principal investigators: Keezer, Mark; House, Andrew A; Larochelle, Catherine; Major, Philippe

Keywords: Biomarkers; Epilepsy; Immune System; Inflammation; Tuberous Sclerosis Complex

$726,750

Graphical Models and Mendelian randomization to characterize and validate grip strength as well as other measures of frailty in cardiovascular disease

Principal investigatorCIHR2018Catalyst Grant: Analysis of CLSA Data

Principal investigators: Sylvestre, Marie-Pierre; Keezer, Mark

Keywords: Blood Pressure; Cardiovascular Disease; Frailty; Graphical Models; Grip Strength; Mendelian Randomization; Single Nucleotide Polymorphisms

$70,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Neurosciences
Rheumatology
Radiology & Imaging
Biomedical Engineering
Neurology and Neurosurgery
Sciences de l'activité physique
Social and Preventive Medicine
Other

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Biomarkers Dear Professor Keezer, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Transitional objects and objective clinical signs in functional/dissociative seizures and epileptic seizures: A comparative study." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Peripheral and CNS inflammation and injury profiles in children with Tuberous Sclerosis Complex and their association with neurological disability and treatment with mTOR inhibitors: a multicentre, longitudinal study cohort." (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]