Faculty profile

May Faraj

ResearcherCardiovascular Metabolism & Nutrition ResearchUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

May Faraj

Researcher

Cardiovascular Metabolism & Nutrition Research

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
3 publications in the last five years, latest in 2024.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2018.
Supervised 3 trainees who won CIHR awards, most recently in 2013.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

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Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Lipoprotein Metabolism Chronic Inflammation And Innate Immunity Clinical And Basic Studies Insulin Secretion And Sensitivity Ldlr And Cd36 Macrophages Nlrp3 Inflammasome Pcsk9

Latest papers

EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors.
Scientific reports · 2024 · senior author
IL-6 Trans-Signaling Is Increased in Diabetes, Impacted by Glucolipotoxicity, and Associated With Liver Stiffness and Fibrosis in Fatty Liver Disease.
Diabetes · 2023
Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1β pathway in human adipose tissue and macrophages.
Scientific reports · 2023 · senior author

All 21 publications

Latest funding

White adipose tissue LDL receptors and omega-3 as modulators of the risk for type 2 diabetes
CIHR · 2018 · Nominated PI
$738,225
Effect of apoB-lipoproteins and omega-3 fatty acids on the NLRP3 inflammasome, adipose tissue function and dietary fat clearance in obese subjects
CIHR · 2013 · Supervisor
$105,000
The inflammasome and dysfunctional adipose tissue: why should apoB-lipoproteins be targeted in humans
CIHR · 2012 · Nominated PI
$720,054

All 7 grants and awards

21 publications.

EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors.

Lamantia V, Bissonnette S, Beaudry M, Cyr Y, Rosiers CD, Baass A, Faraj M

Scientific reports2024Senior author

DOI: 10.1038/s41598-024-73672-6 PMID: 39511203

IL-6 Trans-Signaling Is Increased in Diabetes, Impacted by Glucolipotoxicity, and Associated With Liver Stiffness and Fibrosis in Fatty Liver Disease.

Gunes A, Schmitt C, Bilodeau L, Huet C, Belblidia A, Baldwin C, Giard JM, Biertho L, Lafortune A, Couture CY, Cheung A, Nguyen BN, Galun E, Bémeur C, Bilodeau M, Laplante M, Tang A, Faraj M, Estall JL

Diabetes2023

DOI: 10.2337/db23-0171 PMID: 37757741

Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1β pathway in human adipose tissue and macrophages.

Bissonnette S, Lamantia V, Ouimet B, Cyr Y, Devaux M, Rabasa-Lhoret R, Chrétien M, Saleh M, Faraj M

Scientific reports2023Senior author

DOI: 10.1038/s41598-023-45870-1 PMID: 37914804

Lower plasma PCSK9 in normocholesterolemic subjects is associated with upregulated adipose tissue surface-expression of LDLR and CD36 and NLRP3 inflammasome.

Cyr Y, Lamantia V, Bissonnette S, Burnette M, Besse-Patin A, Demers A, Wabitsch M, Chrétien M, Mayer G, Estall JL, Saleh M, Faraj M

Physiological reports2021Senior author

DOI: 10.14814/phy2.14721 PMID: 33527668

White Adipose Tissue Surface Expression of LDLR and CD36 is Associated with Risk Factors for Type 2 Diabetes in Adults with Obesity.

Cyr Y, Bissonnette S, Lamantia V, Wassef H, Loizon E, Ngo Sock ET, Vidal H, Mayer G, Chrétien M, Faraj M

Obesity (Silver Spring, Md.)2020Senior author

DOI: 10.1002/oby.22985 PMID: 33043593

LDL, LDL receptors, and PCSK9 as modulators of the risk for type 2 diabetes: a focus on white adipose tissue.

Faraj M

Journal of biomedical research2020First author

DOI: 10.7555/jbr.34.20190124 PMID: 32701068

High plasma apolipoprotein B identifies obese subjects who best ameliorate white adipose tissue dysfunction and glucose-induced hyperinsulinemia after a hypocaloric diet.

Bissonnette S, Saint-Pierre N, Lamantia V, Leroux C, Provost V, Cyr Y, Rabasa-Lhoret R, Faraj M

The American journal of clinical nutrition2018Senior author

DOI: 10.1093/ajcn/nqy070 PMID: 29917037

Enrichment of Triglyceride-Rich Lipoproteins with Apolipoprotein C-I Is Positively Associated with Their Delayed Plasma Clearance Independently of Other Transferable Apolipoproteins in Postmenopausal Overweight and Obese Women.

Wassef H, Bissonnette S, Dufour R, Davignon J, Faraj M

The Journal of nutrition2017Senior author

DOI: 10.3945/jn.116.242750 PMID: 28356429

ApoB-lipoproteins and dysfunctional white adipose tissue: Relation to risk factors for type 2 diabetes in humans.

Lamantia V, Bissonnette S, Wassef H, Cyr Y, Baass A, Dufour R, Rabasa-Lhoret R, Faraj M

Journal of clinical lipidology2017Senior author

DOI: 10.1016/j.jacl.2016.09.013 PMID: 28391908

WAT apoC-I secretion: role in delayed chylomicron clearance in vivo and ex vivo in WAT in obese subjects.

Cyr Y, Wassef H, Bissonnette S, Lamantia V, Davignon J, Faraj M

Journal of lipid research2016Senior author

DOI: 10.1194/jlr.p064170 PMID: 27040450

White adipose tissue LDL receptors and omega-3 as modulators of the risk for type 2 diabetes

Nominated PICIHR2018Project Grant

Principal investigators: Faraj, May

Keywords: Chronic Inflammation And Innate Immunity; Clinical And Basic Studies; Insulin Secretion And Sensitivity; Ldlr And Cd36; Lipoprotein Metabolism; Macrophages; Nlrp3 Inflammasome; Pcsk9; Type 2 Diabetes; White Adipose Tissue

$738,225

Effect of apoB-lipoproteins and omega-3 fatty acids on the NLRP3 inflammasome, adipose tissue function and dietary fat clearance in obese subjects

SupervisorCIHR2013Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Bissonnette, Simon

Keywords: Adipocyte Differentiation; Chronic Inflammation; Elisa / Ria; In Vivo / Ex Vivo / In Vitro; Low Density Lipoproteins; Nlrp3 Inflammasome; Obese Subjects; Radioactive-Labelles Substrates; Real-Time Pcr; White Adipose Tissue Dysfunction

$105,000

The inflammasome and dysfunctional adipose tissue: why should apoB-lipoproteins be targeted in humans

Nominated PICIHR2012Operating Grant

Principal investigators: Faraj, May

Keywords: 16 Wks Omega-3 Fatty Acids Supplementation; Clinical Study In Obese Subjects; In Vivo And And Ex Vivo Models; Innate Immunity And Nlrp3 Inflammasome; Insulin Sensitivity And Secretion; Lipoprotein Metabolism; Postprandial Dietary Fat Clearance; Stable And Radioactive Isotope Tracing; White Adipose Tissue Function

$720,054

ApoB-lipoproteins, adipose tissue NLRP3 inflammasome and insulin resistance

Nominated PICIHR2011Operating Grant-PA: INMD Start Up Funds (bridge funding) - Clinician Scientists

Principal investigators: Faraj, May

Keywords: 12 Weeks Omega-3 Fatty Acids-Rich Diet; In Vivo And And Ex Vivo Human And Mice Models; Innate Immunity And Nlrp3 Inflammasome; Insulin Sensitivity And Secretion; Lipids And Apob-Lipoproteins; Overweight And Obese Subjects; Postprandial Fat Clearance; Stable And Radioactive Isotope Tracing; White Adipose Tissue Function

$100,000

Taux de sécrétion d'insuline et résistance à l'insuline chez des populations en surplus pondéral ayant des taux élevés ou normaux d'apoB-100

SupervisorCIHR2010Master's Award: Canada Graduate Scholarships

Principal investigators: Saint-Pierre, Nathalie

Keywords: Apolipoprotéine B100; Diabète; Endocrinologie; Lipidologie; Métabolisme Des Lipides; Obésité; Physiologie Lipidique; Résistance À L'Insuline

$17,500

The role of apoB100-lipoproteins in fatty acid trapping in obese subjects; in vivo and in vitro models

SupervisorCIHR2010Master's Award: Canada Graduate Scholarships

Principal investigators: Salem, Huda

Keywords: Adipose Tisue Biopsies; Clinical And Basic Research; Ex Vivo And In Vitro Models; In Vivo; Isotope Ration Mass Spectrometry; Lipoprotein Metabolism; Metabolism; Nutrition; Obesity; Stable And Radioactive Isotopes; Type 2 Diabetes

$17,500

Targeting hyperapoB vs normoapoB to reduce the risk of type 2 diabetes in obese subjects; mechanism of action

Nominated PICIHR2008Operating Grant

Principal investigators: Faraj, May

Keywords: 24 Weeks Hypocaloric Diet Intervention; Blood & Adipose Tissue); Fatty Acid Trapping (In Vivo & Ex Vivo In Adipose Tissue); Inflammation (In Vivo & Ex Vivo; Insulin Sensitivity (In Vivo & Ex Vivo In Adipose Tissue); Lipids & Apob-Lipoproteins (Size; Number & Oxidation); Obese Subjects With High Versus Low Serum Apob100

$404,974

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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May Faraj

Research

Latest papers

Latest funding

EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors.

IL-6 Trans-Signaling Is Increased in Diabetes, Impacted by Glucolipotoxicity, and Associated With Liver Stiffness and Fibrosis in Fatty Liver Disease.

Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1β pathway in human adipose tissue and macrophages.

Lower plasma PCSK9 in normocholesterolemic subjects is associated with upregulated adipose tissue surface-expression of LDLR and CD36 and NLRP3 inflammasome.

White Adipose Tissue Surface Expression of LDLR and CD36 is Associated with Risk Factors for Type 2 Diabetes in Adults with Obesity.

LDL, LDL receptors, and PCSK9 as modulators of the risk for type 2 diabetes: a focus on white adipose tissue.

High plasma apolipoprotein B identifies obese subjects who best ameliorate white adipose tissue dysfunction and glucose-induced hyperinsulinemia after a hypocaloric diet.

Enrichment of Triglyceride-Rich Lipoproteins with Apolipoprotein C-I Is Positively Associated with Their Delayed Plasma Clearance Independently of Other Transferable Apolipoproteins in Postmenopausal Overweight and Obese Women.

ApoB-lipoproteins and dysfunctional white adipose tissue: Relation to risk factors for type 2 diabetes in humans.

WAT apoC-I secretion: role in delayed chylomicron clearance in vivo and ex vivo in WAT in obese subjects.

White adipose tissue LDL receptors and omega-3 as modulators of the risk for type 2 diabetes

Effect of apoB-lipoproteins and omega-3 fatty acids on the NLRP3 inflammasome, adipose tissue function and dietary fat clearance in obese subjects

The inflammasome and dysfunctional adipose tissue: why should apoB-lipoproteins be targeted in humans

ApoB-lipoproteins, adipose tissue NLRP3 inflammasome and insulin resistance

Taux de sécrétion d'insuline et résistance à l'insuline chez des populations en surplus pondéral ayant des taux élevés ou normaux d'apoB-100

The role of apoB100-lipoproteins in fatty acid trapping in obese subjects; in vivo and in vitro models

Targeting hyperapoB vs normoapoB to reduce the risk of type 2 diabetes in obese subjects; mechanism of action

Frequent collaborators

May Faraj

Rémi Rabasa-Lhoret

Rémi Rabasa-Lhoret

Maya Saleh

An Tang

Mathieu Laplante

Denis Prud'homme

Marie-Eve Mathieu

Laurent Biertho

Mathieu Laplante

May Faraj

Research

Latest papers

Latest funding

EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1&#x3b2; pathway and its association with diabetes risk factors.

IL-6 Trans-Signaling Is Increased in Diabetes, Impacted by Glucolipotoxicity, and Associated With Liver Stiffness and Fibrosis in Fatty Liver Disease.

Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1&#x3b2; pathway in human adipose tissue and macrophages.

Lower plasma PCSK9 in normocholesterolemic subjects is associated with upregulated adipose tissue surface-expression of LDLR and CD36 and NLRP3 inflammasome.

White Adipose Tissue Surface Expression of LDLR and CD36 is Associated with Risk Factors for Type 2 Diabetes in Adults with Obesity.

LDL, LDL receptors, and PCSK9 as modulators of the risk for type 2 diabetes: a focus on white adipose tissue.

High plasma apolipoprotein B identifies obese subjects who best ameliorate white adipose tissue dysfunction and glucose-induced hyperinsulinemia after a hypocaloric diet.

Enrichment of Triglyceride-Rich Lipoproteins with Apolipoprotein C-I Is Positively Associated with Their Delayed Plasma Clearance Independently of Other Transferable Apolipoproteins in Postmenopausal Overweight and Obese Women.

ApoB-lipoproteins and dysfunctional white adipose tissue: Relation to risk factors for type 2 diabetes in humans.

WAT apoC-I secretion: role in delayed chylomicron clearance in vivo and ex vivo in WAT in obese subjects.

White adipose tissue LDL receptors and omega-3 as modulators of the risk for type 2 diabetes

Effect of apoB-lipoproteins and omega-3 fatty acids on the NLRP3 inflammasome, adipose tissue function and dietary fat clearance in obese subjects

The inflammasome and dysfunctional adipose tissue: why should apoB-lipoproteins be targeted in humans

ApoB-lipoproteins, adipose tissue NLRP3 inflammasome and insulin resistance

Taux de sécrétion d'insuline et résistance à l'insuline chez des populations en surplus pondéral ayant des taux élevés ou normaux d'apoB-100

The role of apoB100-lipoproteins in fatty acid trapping in obese subjects; in vivo and in vitro models

Targeting hyperapoB vs normoapoB to reduce the risk of type 2 diabetes in obese subjects; mechanism of action

Frequent collaborators

May Faraj

Rémi Rabasa-Lhoret

Rémi Rabasa-Lhoret

Maya Saleh

An Tang

Mathieu Laplante

Denis Prud'homme

Marie-Eve Mathieu

Laurent Biertho

Mathieu Laplante

EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors.

Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1β pathway in human adipose tissue and macrophages.