This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Dapagliflozin, in addition to ramipril, ameliorates kidney disease progression in mice with Alport syndrome.
American journal of physiology. Renal physiology · 2025
Canagliflozin inhibits hedgehog interacting protein (Hhip) induction of tubulopathy in diabetic Akita mice.
Translational research : the journal of laboratory and clinical medicine · 2025 · senior author
Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition.
Translational research : the journal of laboratory and clinical medicine · 2024 · senior author
Latest funding
- $925,650
Unlocking the Potential: The Activation of Angiotensin Type 2 Receptor (AT2R) Prevents Diabetic Kidney Disease in a Sex-Specific Manner
CIHR · 2025 · Nominated PI
- $1,490
Renal Tubule-Specific Angiotensinogen Knockout Ameliorates Diabetic Kidney Disease in Type 1 Diabetic Akita Mice
CIHR · 2023 · Supervisor
- $1,500
Canagliflozin Inhibits Hedgehog Interacting Protein (Hhip)-Mediated Renal Tubular Cell Senescence in Type 1 Akita Mice
CIHR · 2023 · Supervisor
37 publications.
Dapagliflozin, in addition to ramipril, ameliorates kidney disease progression in mice with Alport syndrome.
Miyata KN, Smith DM, Yamashita M, Kim S, Yeargin FA, Beganovic M, Zhang SL, Chan JSD, Miner JH, Leal DN, Li JP, Bruno J
Canagliflozin inhibits hedgehog interacting protein (Hhip) induction of tubulopathy in diabetic Akita mice.
Chang SY, Liao MC, Miyata KN, Pang Y, Zhao XP, Peng J, Rivard A, Ingelfinger JR, Chan JSD, Zhang SL
Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition.
Liao MC, Lo CS, Pang YC, Yang WX, Su K, Zhao XP, Miyata KN, Peng J, Ingelfinger JR, Chan JSD, Zhang SL
Hedgehog interacting protein activates sodium-glucose cotransporter 2 expression and promotes renal tubular epithelial cell senescence in a mouse model of type 1 diabetes.
Zhao XP, Chang SY, Pang Y, Liao MC, Peng J, Ingelfinger JR, Chan JSD, Zhang SL
Deletion of heterogeneous nuclear ribonucleoprotein F in renal tubules downregulates SGLT2 expression and attenuates hyperfiltration and kidney injury in a mouse model of diabetes.
Miyata KN, Lo CS, Zhao S, Zhao XP, Chenier I, Yamashita M, Filep JG, Ingelfinger JR, Zhang SL, Chan JSD
AT2R deficiency in mice accelerates podocyte dysfunction in diabetic progeny in a sex-dependent manner.
Liao MC, Pang YC, Chang SY, Zhao XP, Chenier I, Ingelfinger JR, Chan JSD, Zhang SL
Overexpression of Nrf2 in Renal Proximal Tubular Cells Stimulates Sodium-Glucose Cotransporter 2 Expression and Exacerbates Dysglycemia and Kidney Injury in Diabetic Mice.
Zhao S, Lo CS, Miyata KN, Ghosh A, Zhao XP, Chenier I, Cailhier JF, Ethier J, Lattouf JB, Filep JG, Ingelfinger JR, Zhang SL, Chan JSD
Comparison of the effects of insulin and SGLT2 inhibitor on the Renal Renin-Angiotensin system in type 1 diabetes mice.
Miyata KN, Zhao S, Wu CH, Lo CS, Ghosh A, Chenier I, Filep JG, Ingelfinger JR, Zhang SL, Chan JSD
Increased urinary excretion of hedgehog interacting protein (uHhip) in early diabetic kidney disease.
Miyata KN, Zhao XP, Chang SY, Liao MC, Lo CS, Chenier I, Ethier J, Cailhier JF, Lattouf JB, Troyanov S, Chiasson JL, Ingelfinger JR, Chan JSD, Zhang SL
Tubular Deficiency of Heterogeneous Nuclear Ribonucleoprotein F Elevates Systolic Blood Pressure and Induces Glycosuria in Mice.
Lo CS, Miyata KN, Zhao S, Ghosh A, Chang SY, Chenier I, Filep JG, Ingelfinger JR, Zhang SL, Chan JSD
Unlocking the Potential: The Activation of Angiotensin Type 2 Receptor (AT2R) Prevents Diabetic Kidney Disease in a Sex-Specific Manner
Principal investigators: Zhang, Shao-Ling
Keywords: Angiotensin Ii Type 2 Receptor; At2r Deficiency; Cathepsin L; Diabetic Kidney Disease; Renal Proximal Tubular Cell; Senescence; Sex Dimorphism; Tubulointerstitial Fibrosis/Apoptosis
Renal Tubule-Specific Angiotensinogen Knockout Ameliorates Diabetic Kidney Disease in Type 1 Diabetic Akita Mice
Principal investigators: Yang, Wenxia
Keywords: Angiotensinogen
Canagliflozin Inhibits Hedgehog Interacting Protein (Hhip)-Mediated Renal Tubular Cell Senescence in Type 1 Akita Mice
Principal investigators: Chang, Shiao-Ying
Keywords: Sodium-Glucose Cotransporter 2 (Sglt2) Inhibitors
Deficiency Of Hedgehog Interacting Protein (Hhip) In Endothelial Cells Prevents Renal Ischemia Reperfusion -Induced Renal Tubular Cell Injury via the inhibition of NF-KB signaling
Principal investigators: Pang, Yuchao
Keywords: Acute Kidney Injury
Nuclear Factor Erythroid 2-Related Factor 2 (NRF2) and Regulation of Sodium-Glucose Co-Transporter 2 (SGLT2) Expression in Type 2 Diabetes
Principal investigators: Chan, John S
Keywords: Db/Db Mice; Diabetic Kidney Disease; High-Fat Diet-Induced T2d Mice; Hypertension; Nuclear Factor Erythroid 2-Related Factor 2; Oxidative Stress; Renal Proximal Tubular Cell-Specific Transgenic Mice; Renal Tubule-Specific Knockout Mice; Sodium-Glucose Co-Transporter 2; Type 2 Diabetes
The Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Meeting and Investigator Summit
Principal investigators: Torban, Elena
Keywords: Biomarkers; Canadian; Disease Models; Diversity; Genetics; Kidney; Kidney Injury; Knowledge Translation; Mechanisms Of Disease; Molecular Biology
Nuclear Factor Erythroid 2-Related Factor 2 (NRF2) and Regulation of Sodium-Glucose Co-Transporter 2 (SGLT2) Expression in Type 2 Diabetes
Principal investigators: Chan, John S
Keywords: Db/Db Mice; Diabetic Kidney Disease; High-Fat Diet-Induced T2d Mice; Hypertension; Nuclear Factor Erythroid 2-Related Factor 2; Oxidative Stress; Renal Proximal Tubular Cell-Specific Knockout Cells; Renal Tubule-Specific Knockout Mice; Sodium-Glucose Co-Transporter 2; Type 2 Diabetes
Nuclear Factor Erythroid 2-Related Factor 2 (NRF2) and Regulation of Sodium-Glucose Co-Transporter 2 (SGLT2) Expression in Type 2 Diabetes
Principal investigators: Chan, John S
Keywords: Diabetes; Diabetic Kidney Disease; Hyperglycemia; Hypertension; Kidney Specific Knockout Mice; Nuclear Factor Erythroid 2-Related Factor 2; Oxidative Stress; Renal Proximal Tubular Cell-Specific Transgenic Mice; Sodium-Glucose Co-Transporter 2; Type 2 Diabetes
Role of Hedgehog Interacting Protein (Hhip) in Diabetic Kidney Disease
Principal investigators: Zhang, Shao-Ling
Keywords: Diabetic Kidney Disease; Endothelial/Epithelial-To-Mesenchymal Transition; Glomerular Endothelial Cell; Hedgehog Interacting Protein; Knockout Mouse Models; Murine Diabetes Models; Tubular Epithelial Cell; Tubulointerstitial Fibrosis/Apoptosis; Urinary Hhip; Urinary Inflammatory Cytokines
Maternal Diabetes Induces Perinatal Programming of Chronic Kidney Disease: The Role of Hedgehog Interacting Protein (Hhip)
Principal investigators: Zhang, Shao-Ling
Keywords: Chronic Kidney Disease; Hedgehog Interacting Protein; High Fat Diet; Knockout Mouse Models; Maternal Diabetes; Renal Tubular Cells; Renal Programming; Tubulointerstitial Fibrosis/Apoptosis
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medicine
- Centre de recherche
- Medicine/Nephrology
- Other
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