Faculty profile

Thierry Alquier

ResearcherMedicineUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Thierry Alquier

Researcher

Medicine

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
5 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 7 research grants (6 CIHR, 1 NSERC), most recently in 2026.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Hypothalamus Obesity Type 2 Diabetes Lipid Signaling Melanocortin System Neurometabolism Energy Balance & Homeostasis Neuroendocrinology

Latest papers

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis.
Nature metabolism · 2026 · senior author
Blockage of ATGL-mediated breakdown of lipid droplets in microglia alleviates neuroinflammatory and behavioural responses to lipopolysaccharides.
Brain, behavior, and immunity · 2025 · senior author
A consensus guide to preclinical indirect calorimetry experiments
Nature Metabolism · 2025

All 35 publications

Latest funding

Microglial lipid droplets as regulators of metabolic homeostasis
CIHR · 2026 · Nominated PI
$1,005,976
Astrocytic glucocorticoid signaling in the PVN tunes stress adaptation
CIHR · 2025 · Principal investigator
$1,189,575
62th International Conference on the Bioscience of Lipids(ICBL) : Lipids in Metabolic Health and Diseases
CIHR · 2022 · Co-investigator
$10,000

All 12 grants and awards

35 publications.

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis.

Manceau R, Cherian CM, Majeur D, Miller CJ, Fisher JD, Boisjoly F, Liston JB, Bako JA, Wat LW, Chao CF, Labarre A, Hollman S, Prakash S, Audet S, Depaauw-Holt L, Rogers B, Bosson A, Biswas P, Xi JJY, Callow CAS, Yoosefi N, Schikora N, Shahraki N, Xia YH, Hui A, VanderZwaag J, Bouyakdan K, Rodaros D, Kotchetkov P, Daneault C, Fallahpour G, Tetreault M, Tremblay MÈ, Ruiz M, Lacoste B, Parker JA, Murphy-Royal C, Huan T, Fulton S, Rideout EJ, Alquier T

Nature metabolism2026Senior author

DOI: 10.1038/s42255-026-01508-w PMID: 41981110

Blockage of ATGL-mediated breakdown of lipid droplets in microglia alleviates neuroinflammatory and behavioural responses to lipopolysaccharides.

Robb JL, Boisjoly F, Machuca-Parra AI, Coursan A, Manceau R, Majeur D, Rodaros D, Bouyakdan K, Greffard K, Bilodeau JF, Forest A, Daneault C, Ruiz M, Laurent C, Arbour N, Layé S, Fioramonti X, Madore C, Fulton S, Alquier T, Representative of consortium

Brain, behavior, and immunity2025Senior author

DOI: 10.1016/j.bbi.2024.09.027 PMID: 39326768

A consensus guide to preclinical indirect calorimetry experiments

Banks AS, Allison DB, Alquier T, Ansarullah, Austad SN, Auwerx J, Ayala JE, Baur JA, Carobbio S, Churchill GA

Nature Metabolism202539 citations

DOI: 10.1038/s42255-025-01360-4

16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice.

Béland-Millar A, Kirby A, Truong Y, Ouellette J, Yandiev S, Bouyakdan K, Pileggi C, Naz S, Yin M, Carrier M, Kotchetkov P, St-Pierre MK, Tremblay MÈ, Courchet J, Harper ME, Alquier T, Messier C, Shuhendler AJ, Lacoste B

Cell reports2023

DOI: 10.1016/j.celrep.2023.112485 PMID: 37149866

Role of astroglial ACBP in energy metabolism flexibility and feeding responses to metabolic challenges in male mice.

Bouyakdan K, Manceau R, Robb JL, Rodaros D, Fulton S, Alquier T

Journal of neuroendocrinology2022Senior author

DOI: 10.1111/jne.13218 PMID: 36471907

Distinct Basal Metabolism in Three Mouse Models of Neurodevelopmental Disorders.

Menzies C, Naz S, Patten D, Alquier T, Bennett BM, Lacoste B

eNeuro2021

DOI: 10.1523/eneuro.0292-20.2021 PMID: 33820803

The Tetracycline-Controlled Transactivator (Tet-On/Off) System in β-Cells Reduces Insulin Expression and Secretion in Mice.

Jouvet N, Bouyakdan K, Campbell SA, Baldwin C, Townsend SE, Gannon MA, Poitout V, Alquier T, Estall JL

Diabetes2021

DOI: 10.2337/db21-0147 PMID: 34610983

From benzodiazepines to fatty acids and beyond: revisiting the role of ACBP/DBI.

Alquier T, Christian-Hinman CA, Alfonso J, Færgeman NJ

Trends in endocrinology and metabolism: TEM2021First author

DOI: 10.1016/j.tem.2021.08.009 PMID: 34565656

Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity.

Diaz-Marin R, Crespo-Garcia S, Wilson AM, Buscarlet M, Dejda A, Fournier F, Juneau R, Alquier T, Sapieha P

Scientific reports2021

DOI: 10.1038/s41598-021-95064-w PMID: 34344941

Fish oil supplementation alleviates metabolic and anxiodepressive effects of diet-induced obesity and associated changes in brain lipid composition in mice.

Demers G, Roy J, Machuca-Parra AI, Dashtehei Pour Z, Bairamian D, Daneault C, Rosiers CD, Ferreira G, Alquier T, Fulton S, Representative of consortium

International journal of obesity (2005)2020

DOI: 10.1038/s41366-020-0623-6 PMID: 32546855

Microglial lipid droplets as regulators of metabolic homeostasis

Nominated PICIHR2026Project Grant

Principal investigators: Alquier, Thierry

Keywords: Energy And Glucose Homeostasis; Hypothalamus; Lipid Signaling; Melanocortin System; Microglia; Neuroimmune Functions; Neuroinflammation; Neurometabolism; Obesity; Type 2 Diabetes

$1,005,976

Astrocytic glucocorticoid signaling in the PVN tunes stress adaptation

Principal investigatorCIHR2025Project Grant

Principal investigators: Murphy-Royal, Ciaran; Alquier, Thierry

Keywords: Astrocyte-Neuron Interactions; Hpa Axis; Neurobiology Of Stress; Stress Adaptation

$1,189,575

62th International Conference on the Bioscience of Lipids(ICBL) : Lipids in Metabolic Health and Diseases

Co-investigatorCIHR2022Planning and Dissemination Grant - Institute Community Support

Principal investigators: Mounier, Catherine

Keywords: Cardiovascular Diseases; Ceramides And Endocannabinoids; Cholesterol Transport; Fluxolipidomics; Inflammation; Lipid Desaturation; Lipid Metabolism; Lipids In Neuronal Systems; Metabolic Diseases; Triacylglycerols

$10,000

Understanding sex differences in the neuronal control of whole-body fat storage and breakdown

Co-investigatorCIHR2022Project Grant

Principal investigators: Rideout, Elizabeth J

Keywords: Body Fat; Drosophila; Genetics; Metabolic Hormones; Neurons; Sex Differences; Triglyceride Metabolism

$677,026

Central control of energy homeostasis by neuronal adipose triglyceride lipase

Nominated PICIHR2021Project Grant

Principal investigators: Alquier, Thierry; Rideout, Elizabeth J

Keywords: Energy Balance & Homeostasis; Feeding Behavior; Hypothalamus; Lipid Signaling; Melanocortin System; Neuroendocrinology; Neurometabolism; Obesity; Type 2 Diabetes

$963,900

Microglial fatty acid signalling as a modulator of diet-induced neuroimmune responses in obesity

Co-investigatorCIHR2019Project Grant

Principal investigators: Fulton, Stephanie

Keywords: Inflammation; Lipids; Neurobiology; Obesity

$940,950

Role of PEDF/ATGL signalling in the central control of energy homeostasis

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Alquier, Thierry

$192,000

Targeting alpha-beta-hydrolase domain 6 in the neural control of body weight, reward and mood

Co-investigatorCIHR2016Project Grant

Principal investigators: Fulton, Stephanie

Keywords: Endocannabinoids; Energy Expenditure; Feeding; Gaba; Mood; Motivation; Neuropharmacology; Nucleus Accumbens; Obesity; Reward

$497,249

Correction of brain triglyceride metabolism in Alzheimer's disease

Co-investigatorCIHR2016Project Grant

Principal investigators: Fernandes, Karl J

Keywords: Alzheimer'S Disease; Anxiety; Diet; Exercise; Fatty Acids; Learning And Memory; Lipid Metabolism; Neural Stem Cells; Neurogenesis; Triglycerides

$856,240

Gliopeptidic regulation of hypothalamic neuronal circuitry by endozepines and energy balance

Nominated PICIHR2016Project Grant

Principal investigators: Alquier, Thierry

Keywords: Astrocytes; Central Nervous System; Endozepines; Energy Balance & Homeostasis; Gliotransmission; Hypothalamus; Melanocortin; Neuroendocrinology; Obesity; Type 2 Diabetes

$749,700

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Thierry Alquier

Research

Latest papers

Latest funding

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis.

Blockage of ATGL-mediated breakdown of lipid droplets in microglia alleviates neuroinflammatory and behavioural responses to lipopolysaccharides.

A consensus guide to preclinical indirect calorimetry experiments

16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice.

Role of astroglial ACBP in energy metabolism flexibility and feeding responses to metabolic challenges in male mice.

Distinct Basal Metabolism in Three Mouse Models of Neurodevelopmental Disorders.

The Tetracycline-Controlled Transactivator (Tet-On/Off) System in &#x3b2;-Cells Reduces Insulin Expression and Secretion in Mice.

From benzodiazepines to fatty acids and beyond: revisiting the role of ACBP/DBI.

Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity.

Fish oil supplementation alleviates metabolic and anxiodepressive effects of diet-induced obesity and associated changes in brain lipid composition in mice.

Role of PEDF/ATGL signalling in the central control of energy homeostasis

Frequent collaborators

Stephanie Fulton

Stephanie Fulton

Vincent Poitout

Baptiste Lacoste

Marc Prentki

Shao-Ling Zhang

Lawrence Kazak

Matthieu Ruiz

Ciaran Murphy-Royal

CHEOLHO Cheong

Przemyslaw Sapieha

Mathieu Ferron

Mary-Ellen Harper

Jacques Thibodeau

Przemyslaw Sapieha

Gregory Steinberg

Christine Des Rosiers

Guy Cloutier

An Tang

The Tetracycline-Controlled Transactivator (Tet-On/Off) System in β-Cells Reduces Insulin Expression and Secretion in Mice.