Viktor Steimle, Université de Sherbrooke

Latest papers

The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins.
International journal of molecular sciences · 2021 · senior author
NLRC5 elicits antitumor immunity by enhancing processing and presentation of tumor antigens to CD8(+) T lymphocytes.
Oncoimmunology · 2016
Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III.
PloS one · 2016 · senior author

All 5 publications

Latest funding

Acquisition of a focused-ultrasonicator system
NSERC · 2021 · Co-investigator
$124,105
Acquisition of an Automated High-Throughput Cell Imaging System
NSERC · 2018 · Co-investigator
$150,000
Molecular Mechanisms of Major histocompatibility complex (MHC) gene regulation
NSERC · 2016 · Principal investigator
$186,000

All 12 grants and awards

5 publications.

01

The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins.

León Machado JA, Steimle V

International journal of molecular sciences2021Senior author

DOI: 10.3390/ijms22031074 PMID: 33499042

02

NLRC5 elicits antitumor immunity by enhancing processing and presentation of tumor antigens to CD8(+) T lymphocytes.

Rodriguez GM, Bobbala D, Serrano D, Mayhue M, Champagne A, Saucier C, Steimle V, Kufer TA, Menendez A, Ramanathan S, Ilangumaran S

Oncoimmunology2016

DOI: 10.1080/2162402x.2016.1151593 PMID: 27471621

03

Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III.

Beaulieu YB, Leon Machado JA, Ethier S, Gaudreau L, Steimle V

PloS one2016Senior author

DOI: 10.1371/journal.pone.0148753 PMID: 26871568

04

The N-terminal domain of NLRC5 confers transcriptional activity for MHC class I and II gene expression.

Neerincx A, Jakobshagen K, Utermöhlen O, Büning H, Steimle V, Kufer TA

Journal of immunology (Baltimore, Md. : 1950)2014

DOI: 10.4049/jimmunol.1401065 PMID: 25127861

05

Activation of ERα signaling differentially modulates IFN-γ induced HLA-class II expression in breast cancer cells.

Mostafa AA, Codner D, Hirasawa K, Komatsu Y, Young MN, Steimle V, Drover S

PloS one2014

DOI: 10.1371/journal.pone.0087377 PMID: 24475282

Acquisition of a focused-ultrasonicator system

Co-investigatorNSERC2021Research Tools and Instruments

Principal investigators: Gévry, Nicolas

$124,105

Acquisition of an Automated High-Throughput Cell Imaging System

Co-investigatorNSERC2018Research Tools and Instruments

Principal investigators: Maréchal, Alexandre

$150,000

Molecular Mechanisms of Major histocompatibility complex (MHC) gene regulation

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Steimle, Viktor

$186,000

Acquisition of a Fluorescence-Activated Cell Sorter (FACS)

Co-investigatorNSERC2015Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Rodrigue, Sébastien

$150,000

Imaging system for quantification of DNA, RNA, and proteins

Co-investigatorNSERC2014Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Lafontaine, Daniel

$136,406

Acquisition of an ultracentrifuge / Acquisition d'une ultracentrifugeuse

Co-investigatorNSERC2011Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Moffett, Peter

$149,806

Regulation of MHC class II genes and molecules

Principal investigatorNSERC2010Discovery Grants Program - Individual

Principal investigators: Steimle, Viktor

$135,000

Regulation of MHC class II genes and molecules

Principal investigatorNSERC2008Discovery Grants Program - Individual

Principal investigators: Steimle, Viktor

$60,000

Appareillage pour la préparation d'echabtillons destinés à la microscopie optique

Co-investigatorNSERC2008Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Langelier, Eve

$89,575

3D imaging system

Co-investigatorNSERC2007Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Beaudoin, Nathalie

$46,984

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biologie
Immunologie-Biologie Cellulaire
Microbiologie et d'infectiologie
Anatomie et biologie cellulaire
Medicine, Faculty of

Co-authors at Université de Sherbrooke, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Kensuke Hirasawa

Medicine, Faculty of

1 shared papers, latest 2014

Sheela Ramanathan

Immunologie-Biologie Cellulaire

1 shared papers, latest 2016

Subburaj Ilangumaran

Immunologie-Biologie Cellulaire

1 shared papers, latest 2016

Alfredo Menendez

Microbiologie et d'infectiologie

1 shared papers, latest 2016

Caroline Saucier

Anatomie et biologie cellulaire

1 shared papers, latest 2016

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Subject: Prospective PhD student Dear Professor Steimle, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins." (2021), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Viktor Steimle

Latest papers

Latest funding

The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins.

NLRC5 elicits antitumor immunity by enhancing processing and presentation of tumor antigens to CD8(+) T lymphocytes.

Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III.

The N-terminal domain of NLRC5 confers transcriptional activity for MHC class I and II gene expression.

Activation of ER&#x3b1; signaling differentially modulates IFN-&#x3b3; induced HLA-class II expression in breast cancer cells.

Acquisition of a focused-ultrasonicator system

Acquisition of an Automated High-Throughput Cell Imaging System

Molecular Mechanisms of Major histocompatibility complex (MHC) gene regulation

Acquisition of a Fluorescence-Activated Cell Sorter (FACS)

Imaging system for quantification of DNA, RNA, and proteins

Acquisition of an ultracentrifuge / Acquisition d'une ultracentrifugeuse

Regulation of MHC class II genes and molecules

Regulation of MHC class II genes and molecules

Appareillage pour la préparation d'echabtillons destinés à la microscopie optique

3D imaging system

Frequent collaborators

Luc Gaudreau

Kensuke Hirasawa

Sheela Ramanathan

Subburaj Ilangumaran

Alfredo Menendez

Caroline Saucier

Activation of ERα signaling differentially modulates IFN-γ induced HLA-class II expression in breast cancer cells.