Luc Gaudreau, Université de Sherbrooke

Research

Chromatin Gene expression H2A.Z Histone Yeast

Latest papers

A novel modulator of IL-6R prevents inflammation-induced preterm birth and improves newborn outcome.
EMBO molecular medicine · 2025
Chromatin Immunoprecipitation Assays of Histone Modifications in Daphnia magna.
Methods in molecular biology (Clifton, N.J.) · 2025 · senior author
A Method for H2A.Z/H2B Dimer Exchange Within Nucleosomes In Vitro.
Methods in molecular biology (Clifton, N.J.) · 2025 · senior author

All 42 publications

Latest funding

Acquisition of a focused-ultrasonicator system
NSERC · 2021 · Co-investigator
$124,105
Acquisition of a Fluorescence and Chemiluminescence Imaging Platform
NSERC · 2020 · Co-investigator
$53,588
Acquisition of a triple quadrupole mass spectrometer
NSERC · 2019 · Co-investigator
$149,995

All 28 grants and awards

42 publications.

01

A novel modulator of IL-6R prevents inflammation-induced preterm birth and improves newborn outcome.

Côté F, Prairie E, Sierra EM, Quiniou C, Habelrih T, Xu W, Ferri B, Hou X, Lahaie I, Côté N, Loiselle SE, Gobeil L, Sawaya K, Faucher A, Beaulieu A, Delisle S, Simard MP, Mohammad Nezhady MA, Laplante V, Reuben A, Kalaidji SM, Bajon E, Cagnone G, Leimert KB, Gauchat JF, Gaudreau L, Robertson S, Lubell WD, Olson DM, Chemtob S

EMBO molecular medicine2025

DOI: 10.1038/s44321-025-00257-9 PMID: 40610814

02

Chromatin Immunoprecipitation Assays of Histone Modifications in Daphnia magna.

Côté N, Benregaya S, Cabana J, Fortin É, Gagnon F, Gaudreau L

Methods in molecular biology (Clifton, N.J.)2025Senior author

DOI: 10.1007/978-1-0716-4486-7_11 PMID: 40257564

03

A Method for H2A.Z/H2B Dimer Exchange Within Nucleosomes In Vitro.

Guillemette B, Laflamme L, Gaudreau L

Methods in molecular biology (Clifton, N.J.)2025Senior author

DOI: 10.1007/978-1-0716-4486-7_3 PMID: 40257556

04

Differential effects of pesticides on dioxin receptor signaling and p53 activation.

Fauteux M, Côté N, Bergeron S, Maréchal A, Gaudreau L

Scientific reports2023Senior author

DOI: 10.1038/s41598-023-48555-x PMID: 38040841

05

Are 20-hydroxyecdysone and related genes potential biomarkers of sublethal exposure to lipid-altering contaminants?

Alarie H, Côté N, Gaudreau L, Houde M, Segura PA

Environmental science and pollution research international2023

DOI: 10.1007/s11356-023-31087-2 PMID: 38010540

06

The Histone Variant H2A.Z C-Terminal Domain Has Locus-Specific Differential Effects on H2A.Z Occupancy and Nucleosome Localization.

Neumann H, Jeronimo C, Lucier JF, Pasquier E, Robert F, Wellinger RJ, Gaudreau L

Microbiology spectrum2023Senior author

DOI: 10.1128/spectrum.02550-22 PMID: 36815792

07

Publisher Correction: Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE.

Boldrin F, Cioetto Mazzabò L, Anoosheh S, Palù G, Gaudreau L, Manganelli R, Provvedi R

Scientific reports2019

DOI: 10.1038/s41598-019-54232-9 PMID: 31754178

08

Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE.

Boldrin F, Cioetto Mazzabò L, Anoosheh S, Palù G, Gaudreau L, Manganelli R, Provvedi R

Scientific reports2019

DOI: 10.1038/s41598-019-41183-4 PMID: 30872756

09

Cellular Depletion of BRD8 Causes p53-Dependent Apoptosis and Induces a DNA Damage Response in Non-Stressed Cells.

Lashgari A, Fauteux M, Maréchal A, Gaudreau L

Scientific reports2018Senior author

DOI: 10.1038/s41598-018-32323-3 PMID: 30237520

10

Global inhibition of transcription causes an increase in histone H2A.Z incorporation within gene bodies.

Lashgari A, Millau JF, Jacques PÉ, Gaudreau L

Nucleic acids research2017Senior author

DOI: 10.1093/nar/gkx879 PMID: 29036442

Acquisition of a focused-ultrasonicator system

Co-investigatorNSERC2021Research Tools and Instruments

Principal investigators: Gévry, Nicolas

$124,105

Acquisition of a Fluorescence and Chemiluminescence Imaging Platform

Co-investigatorNSERC2020Research Tools and Instruments

Principal investigators: Maréchal, Alexandre

$53,588

Acquisition of a triple quadrupole mass spectrometer

Co-investigatorNSERC2019Research Tools and Instruments

Principal investigators: Bellenger, JeanPhilippe

$149,995

Role of histone tails in gene expression and cellular functions

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Gaudreau, Luc

Keywords: Chromatin; Gene expression; H2A.Z; H3; H4; Histone; Yeast

$252,000

Acquisition of an Automated High-Throughput Cell Imaging System

Co-investigatorNSERC2018Research Tools and Instruments

Principal investigators: Maréchal, Alexandre

$150,000

Acquisition of an in vivo imaging system

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Gévry, Nicolas

$144,824

High throughput extraction platform for the analysis of organic compounds in solid and semi-solid matrices

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Bellenger, JeanPhilippe

$127,900

Use of gene regulatory sensors to monitor environmental pollutant levels in small mammals and birds

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: Gaudreau, Luc

$30,000

Acquisition of a Fluorescence-Activated Cell Sorter (FACS)

Co-investigatorNSERC2015Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Rodrigue, Sébastien

$150,000

Imaging system for quantification of DNA, RNA, and proteins

Co-investigatorNSERC2014Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Lafontaine, Daniel

$136,406

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biologie
Obstétrique et gynécologie
Pediatrics

Co-authors at Université de Sherbrooke, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Pierre-Étienne Jacques

Obstétrique et gynécologie

5 shared papers, latest 2009

Sylvain Chemtob

Pediatrics

1 shared papers, latest 2025

Viktor Steimle

Biologie

1 shared papers, latest 2016

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Subject: Prospective PhD student: Chromatin Dear Professor Gaudreau, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "A novel modulator of IL-6R prevents inflammation-induced preterm birth and improves newborn outcome." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]