Uladzimir Karniychuk

Research

Fetal Infection Flavivirus Hematopoietic Stem Cells Immunopathology Offspring Zika Virus

Latest papers

Elegant and Innovative Recoding Strategies for Advancing Vaccine Development.
Vaccines · 2025 · senior author
West Nile virus vaccine candidates attenuated by dinucleotide enrichment are immunogenic and protective against lethal infection.
PLoS pathogens · 2025 · senior author
Asian Zika virus can acquire generic African-lineage mutations during in utero infection.
Emerging microbes & infections · 2023 · senior author

All 19 publications

Latest funding

Animal models for SARS-CoV-2: vaccines and immune enhancement
CIHR · 2020 · Co-investigator
$999,793
Hematopoietic stem cell sequelae in fetuses and offspring exposed to in utero Zika infection
CIHR · 2020 · Nominated PI
$581,400
The Bhagirath Singh Early Career Prize in Infection and Immunity: Hematopoietic stem cell sequelae in fetuses and offspring exposed to in utero Zika infection
CIHR · 2020 · Nominated PI
$12,500

All 7 grants and awards

19 publications.

01

Elegant and Innovative Recoding Strategies for Advancing Vaccine Development.

Meurens F, Renois F, Karniychuk U

Vaccines2025Senior author

DOI: 10.3390/vaccines13010078 PMID: 39852857

02

West Nile virus vaccine candidates attenuated by dinucleotide enrichment are immunogenic and protective against lethal infection.

Le NPK, Singh PP, Trus I, Karniychuk U

PLoS pathogens2025Senior author

DOI: 10.1371/journal.ppat.1013560 PMID: 41042818

03

Asian Zika virus can acquire generic African-lineage mutations during in utero infection.

Sabir AJ, Singh PP, Trus I, Le NPK, Karniychuk U

Emerging microbes & infections2023Senior author

DOI: 10.1080/22221751.2023.2263592 PMID: 37747060

04

Offspring affected with in utero Zika virus infection retain molecular footprints in the bone marrow and blood cells.

Udenze D, Trus I, Lipsit S, Napper S, Karniychuk U

Emerging microbes & infections2023Senior author

DOI: 10.1080/22221751.2022.2147021 PMID: 36369716

05

CpG content in the Zika virus genome affects infection phenotypes in the adult brain and fetal lymph nodes.

Udenze D, Trus I, Berube N, Karniychuk U

Frontiers in immunology2022Senior author

DOI: 10.3389/fimmu.2022.943481 PMID: 35983032

06

Japanese encephalitis virus persists in the human reproductive epithelium and porcine reproductive tissues.

Chapagain S, Pal Singh P, Le K, Safronetz D, Wood H, Karniychuk U

PLoS neglected tropical diseases2022Senior author

DOI: 10.1371/journal.pntd.0010656 PMID: 35905074

07

Generation of CpG-Recoded Zika Virus Vaccine Candidates.

Trus I, Udenze D, Karniychuk U

Methods in molecular biology (Clifton, N.J.)2022Senior author

DOI: 10.1007/978-1-0716-1884-4_14 PMID: 34914053

08

The Isolated in Utero Environment Is Conducive to the Emergence of RNA and DNA Virus Variants.

Udenze D, Trus I, Munyanduki H, Berube N, Karniychuk U

Viruses2021Senior author

DOI: 10.3390/v13091827 PMID: 34578408

09

Susceptibility of Chicken Embryos, Sheep, Cattle, Pigs, and Chickens to Zika Virus Infection.

Ambagala A, Truong T, Cottam-Birt C, Berhane Y, Gerdts V, Karniychuk U, Safronetz D, Babiuk S

Frontiers in veterinary science2020

DOI: 10.3389/fvets.2020.00023 PMID: 32118055

10

Zika Virus with Increased CpG Dinucleotide Frequencies Shows Oncolytic Activity in Glioblastoma Stem Cells.

Trus I, Berube N, Jiang P, Rak J, Gerdts V, Karniychuk U

Viruses2020Senior author

DOI: 10.3390/v12050579 PMID: 32466170

Animal models for SARS-CoV-2: vaccines and immune enhancement

Co-investigatorCIHR2020Operating Grant: COVID-19 - Vaccines

Principal investigators: Falzarano, Darryl

Keywords: Animal Model; Coronavirus; Covid-19; Immune Enhancement; One Health; Pre-Existing Immunity; Sars-Cov; Sars-Cov-2; Transmission; Vaccine

$999,793

Hematopoietic stem cell sequelae in fetuses and offspring exposed to in utero Zika infection

Nominated PICIHR2020Project Grant

Principal investigators: Karniychuk, Uladzimir

Keywords: Fetal Infection; Flavivirus; Hematopoietic Stem Cells; Immunopathology; Offspring; Zika Virus

$581,400

The Bhagirath Singh Early Career Prize in Infection and Immunity: Hematopoietic stem cell sequelae in fetuses and offspring exposed to in utero Zika infection

Nominated PICIHR2020PRIZE - Pro. - PA: The Bhagirath Singh Early Career Award in Infection and Immu.

Principal investigators: Karniychuk, Uladzimir

Keywords: Fetal Infection; Flavivirus; Hematopoietic Stem Cells; Immunopathology; Offspring; Zika Virus

$12,500

Sex as a Biological Variable Supplement - Animal models for SARS-CoV-2: vaccines and immune enhancement

Co-investigatorCIHR2020Op Grant: Sex as a Biological Variable Supplement: COVID-19 Rapid Research FO

Principal investigators: Falzarano, Darryl

Keywords: Animal Model; Coronavirus.; Covid-19; Immune Enhancement; One Health; Pre-Existing Immunity; Sars-Cov; Sars-Cov-2; Transmission; Vaccine

$50,000

Infection phenotypes of CpG-recoded RNA viruses in animal models with immature immunity

Principal investigatorNSERC2018Discovery Launch Supplement

Principal investigators: Karniychuk, Uladzimir

$12,500

Towards in utero therapy against congenital viral infections

Principal investigatorSSHRC2018New Frontiers in Research Fund

Principal investigators: Karniychuk, Uladzimir

Keywords: congenital infection, animal model, antiviral therapy, brain-penetrating protein, fetus, Zika virus

$273,310

Infection phenotypes of CpG-recoded RNA viruses in animal models with immature immunity

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Karniychuk, Uladzimir

$185,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Department of Physiology
Microbiologie et d'infectiologie
Pediatrics
Department of Laboratory Medicine and Pathobiology
Other

Co-authors at University of Saskatchewan, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Brian Cox

Department of Physiology

3 shared papers, latest 2019

Gary Kobinger

Microbiologie et d'infectiologie

1 shared papers, latest 2019

Tony Mazzulli

Department of Laboratory Medicine and Pathobiology

1 shared papers, latest 2017

Chris Verschoor

Medicine

1 shared papers, latest 2017

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2020

Subject: Prospective PhD student: Fetal Infection Dear Professor Karniychuk, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Elegant and Innovative Recoding Strategies for Advancing Vaccine Development." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Hematopoietic stem cell sequelae in fetuses and offspring exposed to in utero Zika infection" (2020), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Uladzimir Karniychuk

Research

Latest papers

Latest funding

Elegant and Innovative Recoding Strategies for Advancing Vaccine Development.

West Nile virus vaccine candidates attenuated by dinucleotide enrichment are immunogenic and protective against lethal infection.

Asian Zika virus can acquire generic African-lineage mutations during in utero infection.

Offspring affected with in utero Zika virus infection retain molecular footprints in the bone marrow and blood cells.

CpG content in the Zika virus genome affects infection phenotypes in the adult brain and fetal lymph nodes.

Japanese encephalitis virus persists in the human reproductive epithelium and porcine reproductive tissues.

Generation of CpG-Recoded Zika Virus Vaccine Candidates.

The Isolated in Utero Environment Is Conducive to the Emergence of RNA and DNA Virus Variants.

Susceptibility of Chicken Embryos, Sheep, Cattle, Pigs, and Chickens to Zika Virus Infection.

Zika Virus with Increased CpG Dinucleotide Frequencies Shows Oncolytic Activity in Glioblastoma Stem Cells.

Animal models for SARS-CoV-2: vaccines and immune enhancement

Hematopoietic stem cell sequelae in fetuses and offspring exposed to in utero Zika infection

The Bhagirath Singh Early Career Prize in Infection and Immunity: Hematopoietic stem cell sequelae in fetuses and offspring exposed to in utero Zika infection

Sex as a Biological Variable Supplement - Animal models for SARS-CoV-2: vaccines and immune enhancement

Infection phenotypes of CpG-recoded RNA viruses in animal models with immature immunity

Towards in utero therapy against congenital viral infections

Infection phenotypes of CpG-recoded RNA viruses in animal models with immature immunity

Frequent collaborators

Volker Gerdts

David Safronetz

Andrew Potter

Brian Cox

Charu Kaushic

Ali A Ashkar

Janusz Rak

Gary Kobinger

Tony Mazzulli

Chris Verschoor