Faculty profile

Brian Cox

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Associate ProfessorDepartment of PhysiologyUniversity of Toronto

Brian Cox

Associate Professor

Department of Physiology

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

ORCID

Supervision signals

Professors usually supervise graduate students in their department's programs.
8 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 16 research grants (10 NSERC, 6 CIHR), most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

185

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Pregnancy Placenta Gene Networks Genomics Systems Biology Fetal Growth Immune Cells Micrornas

Latest papers

The development and impact of an innovative graduate program to promote entry to physiology-related careers: the Master of Health Science in Medical Physiology.
Advances in physiology education · 2026
A Phase 1 Prognostic Trial for Predicting Paediatric Allergy Using the Placenta at Birth.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
Author Correction: A comprehensive human embryo reference tool using single-cell RNA-sequencing data.
Nature methods · 2025

All 38 publications

Latest funding

Systems biology approach to the genetic of preeclampsia
CIHR · 2023 · Nominated PI
$810,900
Role of imprinted microRNAs in fetal growth restrictions affects on placental development and maternal immune tolerance to pregnancy
CIHR · 2021 · Nominated PI
$910,350
Heterogeneity in placental pathology leads to pregnancy pathology
CIHR · 2019 · Nominated PI
$100,000

All 19 grants and awards

38 publications.

The development and impact of an innovative graduate program to promote entry to physiology-related careers: the Master of Health Science in Medical Physiology.

Miliotis H, Buchan A, Wittnich C, Cox B, Brubaker PL, Giacca A, Belsham D

Advances in physiology education2026

DOI: 10.1152/advan.00060.2026 PMID: 42053450

A Phase 1 Prognostic Trial for Predicting Paediatric Allergy Using the Placenta at Birth.

Clifton VL, Saif Z, Balbon AP, Afnan M, Tai A, Kumar S, Davies JM, Sly PD, Peake J, Saffery R, Vuillermin PJ, BIS Investigator Group, Cox B

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology2026

DOI: 10.1111/cea.70272 PMID: 41795204

Author Correction: A comprehensive human embryo reference tool using single-cell RNA-sequencing data.

Zhao C, Plaza Reyes A, Schell JP, Weltner J, Ortega NM, Zheng Y, Björklund ÅK, Baqué-Vidal L, Sokka J, Trokovic R, Cox B, Rossant J, Fu J, Petropoulos S, Lanner F

Nature methods2025

DOI: 10.1038/s41592-025-02601-w PMID: 39856235

A comprehensive human embryo reference tool using single-cell RNA-sequencing data.

Zhao C, Plaza Reyes A, Schell JP, Weltner J, Ortega NM, Zheng Y, Björklund ÅK, Baqué-Vidal L, Sokka J, Trokovic R, Cox B, Rossant J, Fu J, Petropoulos S, Lanner F

Nature methods2025

DOI: 10.1038/s41592-024-02493-2 PMID: 39543283

Heterogeneity in Early Postpartum Metabolic Profiles Among Women with GDM Who Progressed to Type 2 Diabetes During 10-Year Follow-Up: The SWIFT Study.

Khan SR, Rost H, Cox B, Razani B, Alexeeff S, Wheeler MB, Gunderson EP

medRxiv : the preprint server for health sciences2023

DOI: 10.1101/2023.06.13.23291346 PMID: 37398098

Proinflammatory changes in the maternal circulation, maternal-fetal interface, and placental transcriptome in preterm birth.

Couture C, Brien ME, Boufaied I, Duval C, Soglio DD, Enninga EAL, Cox B, Girard S

American journal of obstetrics and gynecology2023

DOI: 10.1016/j.ajog.2022.08.035 PMID: 36027951

Maternal Immune Cell and Cytokine Profiles to Predict Cardiovascular Risk Six Months after Preeclampsia.

Murphy MSQ, Benton SJ, Cox B, Nerenberg K, McComb S, Krishnan L, Weeratna RD, Paré JF, Dingwall-Harvey ALJ, Bainbridge SA, Gruslin A, Gaudet LM

Journal of clinical medicine2022

DOI: 10.3390/jcm11144185 PMID: 35887949

Computational analysis identified accelerated senescence as a significant contribution to preeclampsia pathophysiology.

Siddique N, Cox B

Placenta2022Senior author

DOI: 10.1016/j.placenta.2022.03.005 PMID: 35286929

Human placental gene sets improve analysis of placental pathologies and link trophoblast and cancer invasion genes.

Naismith K, Cox B

Placenta2021Senior author

DOI: 10.1016/j.placenta.2021.06.011 PMID: 34237528

TP63 basal cells are indispensable during endoderm differentiation into proximal airway cells on acellular lung scaffolds.

Bilodeau C, Shojaie S, Goltsis O, Wang J, Luo D, Ackerley C, M Rogers I, Cox B, Post M

NPJ Regenerative medicine2021

DOI: 10.1038/s41536-021-00124-4 PMID: 33674599

Systems biology approach to the genetic of preeclampsia

Nominated PICIHR2023Project Grant

Principal investigators: Cox, Brian J

Keywords: Gene Networks; Genomics; Pregnancy; Systems Biology

$810,900

Role of imprinted microRNAs in fetal growth restrictions affects on placental development and maternal immune tolerance to pregnancy

Nominated PICIHR2021Project Grant

Principal investigators: Cox, Brian J

Keywords: Fetal Growth; Immune Cells; Micrornas; Placenta; Pregnancy

$910,350

Heterogeneity in placental pathology leads to pregnancy pathology

Nominated PICIHR2019Project Grant - PA: Human Development, Child and Youth Health

Principal investigators: Cox, Brian J

Keywords: Copy Number Variants; Gene Expression; Growth Restiction; Histology; Pathology; Placenta; Preeclampsia; Pregnancy

$100,000

Stem cell models of the trophoblast

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Cox, Brian

$198,000

Canada Research Chair - Tier 2

Nominated PICIHR2017Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Cox, Brian J

Keywords: Crc

$500,000

Functions of miRs in the nucleus during cell fate development

Nominated PICIHR2016Project Grant

Principal investigators: Cox, Brian J

Keywords: Development; Epigenetics; Gene Regulation; Microrna; Sequencing; Stem Cells

$672,760

Villous Trophoblast Turnover

Co-investigatorCIHR2014Operating Grant

Principal investigators: Kingdom, John C

Keywords: Exosomes; Heparin; Placenta; Pre-Eclampsia

$719,234

Cellular and molecular systems level analysis of placenta development and function.

Principal investigatorNSERC2013Discovery Grants Program - Individual

Principal investigators: Cox, Brian

$150,000

CRC Tier 1

Nominated PICIHR2012Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Cox, Brian J

Keywords: Crc Tier 1

$500,000

Placental Response to Heparin: Implications for the Prevention of Pre-eclampsia

Co-investigatorCIHR2012Operating Grant

Principal investigators: Kingdom, John C

Keywords: Genetic Regulation; Glial Cell Missing; Heparin; Placental Development; Placental Explants; Placental Insufficiency; Preeclampsia; Villous Cytotrophoblast

$521,660

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Brian Cox

Research

Latest papers

Latest funding

The development and impact of an innovative graduate program to promote entry to physiology-related careers: the Master of Health Science in Medical Physiology.

A Phase 1 Prognostic Trial for Predicting Paediatric Allergy Using the Placenta at Birth.

Author Correction: A comprehensive human embryo reference tool using single-cell RNA-sequencing data.

A comprehensive human embryo reference tool using single-cell RNA-sequencing data.

Heterogeneity in Early Postpartum Metabolic Profiles Among Women with GDM Who Progressed to Type 2 Diabetes During 10-Year Follow-Up: The SWIFT Study.

Proinflammatory changes in the maternal circulation, maternal-fetal interface, and placental transcriptome in preterm birth.

Maternal Immune Cell and Cytokine Profiles to Predict Cardiovascular Risk Six Months after Preeclampsia.

Computational analysis identified accelerated senescence as a significant contribution to preeclampsia pathophysiology.

Human placental gene sets improve analysis of placental pathologies and link trophoblast and cancer invasion genes.

TP63 basal cells are indispensable during endoderm differentiation into proximal airway cells on acellular lung scaffolds.

Stem cell models of the trophoblast

Cellular and molecular systems level analysis of placenta development and function.

Frequent collaborators

Janet Rossant

Andrew Emili

Thomas Kislinger

Uladzimir Karniychuk

Volker Gerdts

David Safronetz

Sophie Petropoulos

Andrew Potter

John Kingdom

Igor Jurisica

Darren Bridgewater

Hannes Rost

Xiao-Yan Wen

Lakshmi Krishnan

Pingzhao Hu

Denise Belsham

Sylvie Girard

Sara Mostafavi

Gary Kobinger

Paul Dorian

Kara Nerenberg

Quaid Morris

Andras Nagy

Kumaraswamy Nanthakumar

Jack Greenblatt

Martin Post

Adria Giacca