Wei Xiao, University of Saskatchewan

Research

Brassica napus Clubroot disease clubroot resistant (CR) cultivar CRISPR/Cas9 genome editing K63-linked polyubiquitination Nanoparticles (NPs)plant transformation Plasmodiophora brassicae

Latest papers

Zinc-finger transcription factor Fzf1 binds to its target DNA in a non-canonical manner.
Nucleic acids research · 2026
Budding Yeast Ubiquitin Ligases Rad5 and Rad18 Bind a Novel PCNA Surface, which Is Required for their Functions in DNA-Damage Tolerance.
International journal of biological sciences · 2026 · senior author
Loss of PMR4 callose synthase triggers jasmonic acid-dependent resistance to the clubroot disease in Arabidopsis and Brassica napus.
The Plant cell · 2026 · senior author

All 98 publications

Latest funding

Investigate and apply the S gene strategy to mitigate the clubroot disease in canola by advanced genome editing technology
NSERC · 2022 · Principal investigator
$719,000
Applying advanced molecular biology, metabolomics and image analysis using machine-learning technology to improve wheat resistance against Fusarium head blight
NSERC · 2021 · Co-investigator
$825,205
Transcriptional regulation of the budding yeast DDI2 gene in response to environmental stresses
NSERC · 2019 · Principal investigator
$250,000

All 16 grants and awards

98 publications.

01

Zinc-finger transcription factor Fzf1 binds to its target DNA in a non-canonical manner.

Ma C, Du Y, Xiao W, Moore SA

Nucleic acids research2026

DOI: 10.1093/nar/gkag054 PMID: 41607282

02

Budding Yeast Ubiquitin Ligases Rad5 and Rad18 Bind a Novel PCNA Surface, which Is Required for their Functions in DNA-Damage Tolerance.

Fan L, Du Y, Novecosky A, Luo Y, Xiao W

International journal of biological sciences2026Senior author

DOI: 10.7150/ijbs.124441 PMID: 41943839

03

Loss of PMR4 callose synthase triggers jasmonic acid-dependent resistance to the clubroot disease in Arabidopsis and Brassica napus.

Luo R, Wang L, Wen R, Yang K, Liu X, Gao P, Tu J, Dumonceaux T, Wei Y, Peng G, Xiao W

The Plant cell2026Senior author

DOI: 10.1093/plcell/koag160 PMID: 42234583

04

Zinc-Finger 5 Is an Activation Domain in the Saccharomyces cerevisiae Stress-Responsive Transcription Factor Fzf1.

Du Y, Wang WY, Xiao W

Journal of fungi (Basel, Switzerland)2025Senior author

DOI: 10.3390/jof12010015 PMID: 41590427

05

Zinc finger 4 negatively controls the transcriptional activator Fzf1 in Saccharomyces cerevisiae.

Du Y, Ma C, Moore SA, Xiao W

mLife2024Senior author

DOI: 10.1002/mlf2.12141 PMID: 39359679

06

Dual activities of a silencing information regulator complex in yeast transcriptional regulation and DNA-damage response.

Rybchuk J, Xiao W

mLife2024Senior author

DOI: 10.1002/mlf2.12108 PMID: 38948145

07

Genetic Dissection of Budding Yeast PCNA Mutations Responsible for the Regulated Recruitment of Srs2 Helicase.

Fan L, Zhang W, Rybchuk J, Luo Y, Xiao W

mBio2023Senior author

DOI: 10.1128/mbio.00315-23 PMID: 36861970

08

Transcriptional activation of budding yeast DDI2/3 through chemical modifications of Fzf1.

Lin A, Chumala P, Du Y, Ma C, Wei T, Xu X, Luo Y, Katselis GS, Xiao W

Cell biology and toxicology2023Senior author

DOI: 10.1007/s10565-022-09745-x PMID: 35809138

09

Plant deubiquitinases: from structure and activity to biological functions.

Luo R, Yang K, Xiao W

Plant cell reports2023Senior author

DOI: 10.1007/s00299-022-02962-y PMID: 36567335

10

Systematic characterization of Brassica napus UBC13 genes involved in DNA-damage response and K63-linked polyubiquitination.

Kumasaruge I, Wen R, Wang L, Gao P, Peng G, Xiao W

BMC plant biology2023Senior author

DOI: 10.1186/s12870-023-04035-y PMID: 36631796

Investigate and apply the S gene strategy to mitigate the clubroot disease in canola by advanced genome editing technology

Principal investigatorNSERC2022Alliance Grants

Principal investigators: Xiao, Wei W

Keywords: brassica napus; clubroot disease; clubroot resistant (cr) cultivar; crispr/cas9 genome editing; k63-linked polyubiquitination; nanoparticles (nps); plant transformation; plasmodiophora brassicae; susceptibility (s) genes; tissue culture

$719,000

Applying advanced molecular biology, metabolomics and image analysis using machine-learning technology to improve wheat resistance against Fusarium head blight

Co-investigatorNSERC2021Alliance Grants

Principal investigators: Kutcher, Hadley HR

Keywords: automated imaging system; deoxynivalenol (don); fusarium damage kernel (fdk); fusarium head blight (fhb); genome wide association study (gwas); metabolome; semi-dwarfing allele; wheat resistance; x-ray fluorescence (xrf); x-ray phase contrast imaging (pci)

$825,205