Faculty profile

Yan Zhou

ResearcherVaccine and Infectious Disease OrganizationUniversity of Saskatchewan

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Saskatchewan directory, so their courses may be missing. Find their university profile.

Yan Zhou

Researcher

Vaccine and Infectious Disease Organization

University of Saskatchewan

Saskatoon, Saskatchewan, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
12 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (6 CIHR, 4 NSERC), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Highly Pathogenic Avian Influenza Virus H5n1 Influenza A Virus Immune Response Inflammation And Cell Death Interferon Response Mammary Gland Virus Replication Dairy Cattle

Latest papers

Receptor profiling and growth assessment of influenza A virus in porcine mammary and non-mammary tissues and derived cells.
Journal of virology · 2026 · senior author
Evaluation of beta-propiolactone and AVL-ethanol inactivation protocols for highly pathogenic avian influenza virus in allantoic fluid and cell culture.
Applied and environmental microbiology · 2026 · senior author
Bat-specific adaptations in interferon signaling and GBP1 contribute to enhanced antiviral capacity
Nature Communications · 2025

All 58 publications

Latest funding

Deciphering Mammary Gland Susceptibility to Influenza A Virus Subtype and Immune Pathways Driving to HPAI H5N1 Pathogenesis
CIHR · 2025 · Nominated PI
$1,254,600
Behaviour of Highly Pathogenic Avian Influenza (H5N1) in Cattle and Impact of Virus Gene Signatures on Disease and Potential Transmission to Humans
CIHR · 2024 · Nominated PI
Engineering next-generation messenger RNA vaccines: Reinforcing the mucosal barriers by thermostable dry powder vaccines for inhalation
CIHR · 2024 · Co-investigator
$100,000

All 12 grants and awards

58 publications.

Receptor profiling and growth assessment of influenza A virus in porcine mammary and non-mammary tissues and derived cells.

Barron-Castillo U, Berube N, Swan CL, Javed MA, Aubrey L, Trann J, Gidych M, Shrivastava S, Baid K, Banerjee A, Zhou Y

Journal of virology2026Senior author

DOI: 10.1128/jvi.00615-26 PMID: 42405777

Evaluation of beta-propiolactone and AVL-ethanol inactivation protocols for highly pathogenic avian influenza virus in allantoic fluid and cell culture.

Pessoa N, Berube N, Aubrey L, Van Kessel J, Javed MA, Zhou Y

Applied and environmental microbiology2026Senior author

DOI: 10.1128/aem.02144-25 PMID: 41733352

Bat-specific adaptations in interferon signaling and GBP1 contribute to enhanced antiviral capacity

Gonzalez V, Lobb B, Côté J, Bhuinya A, Tubb AG, Nuthalapati SS, Asavajaru A, Zhou Y, Misra V, Falzarano D

Nature Communications20258 citations

DOI: 10.1038/s41467-025-61254-7

Dairy cows develop protective immunity against reinfection with bovine H5N1 influenza virus.

Facciuolo A, Aubrey L, Barron-Castillo U, Berube N, Norleen C, McCreary S, Huang Y, Pessoa N, Jacome LM, Mubareka S, McGeer A, Berhane Y, Gerdts V, Van Kessel A, Warner B, Zhou Y

Nature microbiology2025Senior author

DOI: 10.1038/s41564-025-01998-6 PMID: 40247094

Approaches for inactivating highly pathogenic avian influenza H5N1 cattle isolate for safe containment level 2 laboratory practices.

Aubrey L, Barron-Castillo U, Berube N, Pessoa N, Macas Jacome L, Trann J, Gentes A, Van Kessel J, Warner B, Facciuolo A, Zhou Y

Applied and environmental microbiology2025Senior author

DOI: 10.1128/aem.02356-24 PMID: 40207970

Influence of Breath-Mimicking Ventilated Incubation on Three-Dimensional Bioprinted Respiratory Tissue Scaffolds.

Zimmerling A, Boire J, Zhou Y, Chen X

Journal of biomechanical engineering2024

DOI: 10.1115/1.4065214 PMID: 38557592

Synthesis of Alginate/Collagen Bioink for Bioprinting Respiratory Tissue Models.

Zimmerling A, Zhou Y, Chen X

Journal of functional biomaterials2024

DOI: 10.3390/jfb15040090 PMID: 38667547

Development of a Nanoparticle System for Controlled Release in Bioprinted Respiratory Scaffolds.

Zimmerling A, Sunil C, Zhou Y, Chen X

Journal of functional biomaterials2024

DOI: 10.3390/jfb15010020 PMID: 38248687

A Bivalent Live Attenuated Influenza Virus Vaccine Protects against Drifted H1N2 and H3N2 Clinical Isolates in Swine.

Aubrey L, Barron-Castillo U, Detmer S, Zhou Y

Viruses2022Senior author

DOI: 10.3390/v15010046 PMID: 36680086

Pirh2 restricts influenza A virus replication by modulating short-chain ubiquitination of its nucleoprotein.

Chen H, Gao X, Zhao S, Bao C, Ming X, Qian Y, Zhou Y, Jung YS

FASEB journal : official publication of the Federation of American Societies for Experimental Biology2022

DOI: 10.1096/fj.202200473r PMID: 36070077

Deciphering Mammary Gland Susceptibility to Influenza A Virus Subtype and Immune Pathways Driving to HPAI H5N1 Pathogenesis

Nominated PICIHR2025Project Grant

Principal investigators: Zhou, Yan

Keywords: Highly Pathogenic Avian Influenza Virus H5n1; Immune Response; Inflammation And Cell Death; Interferon Response; Mammary Gland; Virus Replication

$1,254,600

Behaviour of Highly Pathogenic Avian Influenza (H5N1) in Cattle and Impact of Virus Gene Signatures on Disease and Potential Transmission to Humans

Nominated PICIHR2024Catalyst Grant: Avian Influenza OneHealth Research

Principal investigators: Zhou, Yan; Berhane, Yohannes; Warner, Bryce

Keywords: Dairy Cattle; Highly Pathogenic Avian Influenza Virus H5n1; Infection Model; One Health Approach; Reassortment Pattern; Risk Assessment Of New Emerging Viruses; Transmission To Humans, Agricultural And Wild Animals; Viral Gene Constellation; Virus Behaviour In A New Host; Virus Spillover

Engineering next-generation messenger RNA vaccines: Reinforcing the mucosal barriers by thermostable dry powder vaccines for inhalation

Co-investigatorCIHR2024Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Thakur, Aneesh

Keywords: Animal Models; Drug Delivery; Flow Cytometry; Formulation; Inhalable Vaccines; Messenger Rna; Mucosal Immunity; Nanoparticles; Particle Engineering; Thermostability

$100,000

Imaging-based analyses of virally infected wildlife and livestock cells

Co-investigatorNSERC2024Research Tools and Instruments

Principal investigators: Banerjee, Arinjay

Keywords: animal hosts; coronavirus; Live-cell imaging; livestock; microscopy; Mycobacterium; porcine; swine influenza; wildlife surveillance; zoonotic viruses

$146,662

Behaviour of Highly Pathogenic Avian Influenza (H5N1) in Cattle and Impact of Virus Gene Signatures on Disease and Potential Transmission to Humans

Principal investigatorNSERC2024Alliance Grants

Principal investigators: Zhou, Yan Y

$150,000

Regulation of RIG-I mediated antiviral response upon influenza A virus infection

Nominated PICIHR2023Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Zhou, Yan

Keywords: Influenza A Virus; Innate Immune Response; Interferon; Nucleoprotein Of Influenza A Virus; Rig-I; Rna Triphosphatase

$100,000

Intranasal Vaccines for Pertussis and Influenza Using Novel Formulations of a Triple Adjuvant

Principal investigatorCIHR2020Project Grant

Principal investigators: Wasan, Ellen K; Gerdts, Volker; Zhou, Yan

Keywords: Influenza; Lipids; Nanoparticles; Pertussis; Polymers; Vaccine; Vaccine Adjuvants; Virus

$745,876

Sensing Influenza A virus by RIG-I

Nominated PICIHR2019Project Grant

Principal investigators: Zhou, Yan

Keywords: Cytokine And Chemokine Gene Expression; Influenza A Virus; Konck-In Mice; Nuclear Fraction; Nuclear Rig-I And Cytoplasmic Rig-I; Rig-I Signaling; Rna Seq; Small Aberrant Rna; Trim25 Ubiquitination; Vrnp Reconstitution

$757,350

Regulation of NLRP3 inflammasome activity in response to swine influenza virus infection

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Zhou, Yan

Keywords: ASC; Caspase 1; IL-1 beta; Innate immunity; Mitochondria fission; NLRP3 inflammasome; Pathogenesis; PB1-F2 protein and NS1 protein of influenza A virus; phosphorylation; Swine influenza virus

$348,000

Innate immunity to swine influenza virus in its natural host

Principal investigatorNSERC2011Discovery Grants Program - Individual

Principal investigators: Zhou, Yan

$288,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Highly Pathogenic Avian Influenza Virus H5n1 Dear Professor Zhou, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Receptor profiling and growth assessment of influenza A virus in porcine mammary and non-mammary tissues and derived cells." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Deciphering Mammary Gland Susceptibility to Influenza A Virus Subtype and Immune Pathways Driving to HPAI H5N1 Pathogenesis" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

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Yan Zhou

Research

Latest papers

Latest funding

Receptor profiling and growth assessment of influenza A virus in porcine mammary and non-mammary tissues and derived cells.

Evaluation of beta-propiolactone and AVL-ethanol inactivation protocols for highly pathogenic avian influenza virus in allantoic fluid and cell culture.

Bat-specific adaptations in interferon signaling and GBP1 contribute to enhanced antiviral capacity

Dairy cows develop protective immunity against reinfection with bovine H5N1 influenza virus.

Approaches for inactivating highly pathogenic avian influenza H5N1 cattle isolate for safe containment level 2 laboratory practices.

Influence of Breath-Mimicking Ventilated Incubation on Three-Dimensional Bioprinted Respiratory Tissue Scaffolds.

Synthesis of Alginate/Collagen Bioink for Bioprinting Respiratory Tissue Models.

Development of a Nanoparticle System for Controlled Release in Bioprinted Respiratory Scaffolds.

A Bivalent Live Attenuated Influenza Virus Vaccine Protects against Drifted H1N2 and H3N2 Clinical Isolates in Swine.

Pirh2 restricts influenza A virus replication by modulating short-chain ubiquitination of its nucleoprotein.

Deciphering Mammary Gland Susceptibility to Influenza A Virus Subtype and Immune Pathways Driving to HPAI H5N1 Pathogenesis

Behaviour of Highly Pathogenic Avian Influenza (H5N1) in Cattle and Impact of Virus Gene Signatures on Disease and Potential Transmission to Humans

Engineering next-generation messenger RNA vaccines: Reinforcing the mucosal barriers by thermostable dry powder vaccines for inhalation

Imaging-based analyses of virally infected wildlife and livestock cells

Behaviour of Highly Pathogenic Avian Influenza (H5N1) in Cattle and Impact of Virus Gene Signatures on Disease and Potential Transmission to Humans

Regulation of RIG-I mediated antiviral response upon influenza A virus infection

Intranasal Vaccines for Pertussis and Influenza Using Novel Formulations of a Triple Adjuvant

Sensing Influenza A virus by RIG-I

Regulation of NLRP3 inflammasome activity in response to swine influenza virus infection

Innate immunity to swine influenza virus in its natural host

Frequent collaborators

Qiang Liu

Volker Gerdts

Vikram Misra

Arinjay Banerjee

Susan Detmer

Xiongbiao Chen

Bryce Warner

Yohannes Berhane

Yuliang Wu

George Mutwiri

Jim Xiang

Andrew Doxey

Samira Mubareka

Philip Griebel

Darryl Falzarano

Allison McGeer