Faculty profile
Cheng-Han Lee
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Read how they describe their research on their University of Alberta profile.
Latest papers
Consensus Statement from the Society of Gynecologic Oncology of Canada on Folate Receptor α Testing in Ovarian Cancer.
Current oncology (Toronto, Ont.) · 2026
Epigenetic control of telomeric RNA maintains heterochromatin in telomerase-driven cancers.
Signal transduction and targeted therapy · 2026
Dedifferentiation in endometrial cancer is associated with HLA-I silencing that may be restored by IFN-γ.
The Journal of pathology · 2026 · senior author
Latest funding
- $1,078,650
Dissecting and targeting SWI/SNF loss in de-differentiated endometrial carcinomas
CIHR · 2020 · Co-investigator
- $105,000
Linking Inactivating Mutations in Chromatin Remodeling Complex Subunits to Aggressive Dedifferentiated Endometrial Carcinoma
CIHR · 2016 · Supervisor
- $190,098
Translational research centre to target and characterize normal and cancer stem cell niches
CFI · 2013 · Co-investigator
75 publications.
Consensus Statement from the Society of Gynecologic Oncology of Canada on Folate Receptor α Testing in Ovarian Cancer.
Ma K, Tessier-Cloutier B, Altman AD, Carey MS, Ethier JL, Lau S, Lee CH, Hopkins L, Kieser K, Kumar A, Leung SOA, Nguyen JMV, MacKay H, McGee J, Salman L, Salvador S, Sluce C, Tatar L, Tone AA, Tinker A, Tremblay E, Veneziani AC, Vicus D, Welch S, Windsor Harker S, Brodeur MN
Epigenetic control of telomeric RNA maintains heterochromatin in telomerase-driven cancers.
Price JDW, Vizeacoumar FS, Abuhussein O, Maranda V, Zhang Y, Adachi H, Nguyen K, Kyrylenko L, Rangel-Pozzo A, Dong H, Gong L, Materi A, Walke P, Ganapathysamy A, Denomy C, Freywald T, Dahiya R, Elhasasna H, Saxena A, Vizeacoumar JP, Patel H, Rajamanickam K, de Oliveira DM, Lazell-Wright M, Morales AM, Aggarwal A, Xu JL, Alli N, Munhoz EP, Gao P, Salsman J, Dahiya DK, Kola NS, Gonzalez-Lopez C, Thibault P, Levin M, Dellaire G, Jette N, Groot G, Köbel M, Lee CH, Hopkins L, Krishnan A, Ahmed S, Eskiw C, Barakat KH, Thakur A, Wu Y, DePinho RA, Mai S, Yu YT, Wong JMY, Freywald A, Vizeacoumar FJ
Dedifferentiation in endometrial cancer is associated with HLA-I silencing that may be restored by IFN-γ.
De Leo A, Wickenberg M, Grillini M, Coadǎ CA, Praveen Kumar P, Tong A, Key J, Kim H, Kommoss F, Carey M, Fu Y, Ceccarelli C, Tallini G, LaPointe P, Köbel M, Lee CH
Clinicopathologic and molecular predictors of survival in BRCA-deficient tubo-ovarian high-grade serous carcinoma.
Zwimpfer TA, Fereday S, Pandey A, Ariyaratne D, Jayawardana MW, Twomey L, Laumont CM, Kennedy CJ, Bolithon A, Meagher NS, Milne K, Hamilton P, Alsop J, Antoniou AC, Au-Yeung G, Beckmann MW, Berrington de Gonzalez A, Bisinotto C, Blome F, Bodelon C, Boros J, Brand AH, Carney ME, Cazorla-Jiménez A, Chiu DS, Christie EL, Chudecka-Głaz A, Coulson P, Cushing-Haugen KL, Cybulski C, Darcy KM, David C, Davidson T, Ekici AB, Elishaev E, Emons J, Engler T, Farrell R, Fischer A, García-Closas M, Gentry-Maharaj A, Ghatage P, Glasspool R, Harter P, Hartkopf AD, Hartmann A, Heikaus S, Hernandez BY, Hettiaratchi A, Heublein S, Huntsman DG, Jimenez-Linan M, Jones ME, Kang E, Kaznowska E, Kluz T, Kommoss FKF, Konecny G, Kruitwagen RFPM, Kwon J, Lambrechts D, Lee CH, Lester J, Leung SCY, Leung Y, Linder A, Lissowska J, Loverix L, Lubiński J, Mateoiu C, McNeish IA, Moubarak M, Nelson GS, Nevins N, Olawaiye AB, Olbrecht S, Orsulic S, Osorio A, Quinn CM, Mohan GR, Ray-Coquard I, Rodríguez-Antona C, Roxburgh P, Ruebner M, Salfinger SG, Samra S, Schoemaker MJ, Sinn HP, Sonke GS, Steele L, Stewart CJR, Talhouk A, Tan A, Tarney CM, Taylor SE, Van de Vijver KK, van der Aa MA, Van Gorp T, Van Nieuwenhuysen E, Van-Wagensveld L, Wahner-Hendrickson AE, Walter C, Wang C, Welz J, Wentzensen N, Wilkens LR, Winham SJ, Winterhoff B, Anglesio MS, Berchuck A, Candido Dos Reis FJ, Cohen PA, Conrads TP, Crowe P, Doherty JA, Fasching PA, Fortner RT, García MJ, Gayther SA, Goodman MT, Gronwald J, Harris HR, Heitz F, Horlings HM, Karlan BY, Kelemen LE, Larry Maxwell G, Menon U, Modugno F, Neuhausen SL, Schildkraut JM, Staebler A, Sundfeldt K, Swerdlow AJ, Vergote I, Wu AH, Brenton JD, Pharoah PDP, Pearce CL, Pike MC, Goode EL, Ramus SJ, Köbel M, Nelson BH, DeFazio A, Friedlander ML, Bowtell DDL, Garsed DW
The real-world utility of homologous repair deficiency testing in BRCA1/2 wild-type high-grade serous carcinoma and the utility of MYC amplification as a potential surrogate marker
Radha Maradiya, Mary Kinloch, Antonio De Leo, Dario de Biase, Soufian El Hallani, Giovanni Tallini, Laura Hopkins, Mark S. Carey, Martin Köbel, Cheng-Han Lee, Christa Aubrey
PRRX1 -rearranged Fibroblastic Tumors : A Clinicopathologic and Molecular Study of 18 Cases Including a Novel PRRX1::EP300 Fusion.
Dehner CA, Torres-Mora J, Thangaiah JJ, Oliveira A, Michal M, Malik F, Din NU, Hassan U, Maqbool H, Obeidin F, Caragea M, Lee CH, Schubart C, Agaimy A, Grundtmann B, Melchior L, Talman ML, Gross J, Cheah AL, Thway K, Fisher C, Antonescu CR, Linos K
KAT6B/A::KANSL1 uterine sarcoma - A case with recurrences following uterine morcellation and the development of primary cell line model.
Chen L, Liu J, Nechala I, Praveen Kumar P, Ewanowich C, Levecchia M, Aubrey C, Fu Y, Lee CH
Endometrial carcinoma and immune escape: prognostic relevance of HLA class I loss in NSMP subtype
Marco Grillini, Jacopo Lenzi, Claudio Ceccarelli, Dario de Biase, Thais Maloberti, Sara Coluccelli, Laura Poppi, Riccardo Ciudino, Caterina Ravaioli, Camelia Alexandra Coadǎ, Gloria Ravegnini, Anna Myriam Perrone, Pierandrea De Iaco, Daniela Rubino, Claudio Zamagni, Benedetta Donati, Alessia Ciarrocchi, Sabrina Croce, Martin Köbel, Cheng‐Han Lee, Giovanni Tallini, Antonio De Leo
GREB1 ‐rearranged uterine tumour shares a common DNA methylation signature with ESR1 ‐rearranged UTROSCT
Cheng‐Han Lee, Yow‐Shan Lee, Jennifer A. Bennett, David L. Kolin, Jen‐Chieh Lee, Hsuan‐Ying Huang, Martin Köbel, Mark Sementsov, Brendan Craig Dickson, Christian Koelsche, Friedrich Kommoss, Friedrich Kommoss, Andreas von Deimling, Felix K F Kommoss, Felix K F Kommoss
Beyond BRCA deficiency: Clinical and molecular predictors of survival in patients with BRCA-deficient tubo-ovarian high-grade serous carcinoma.
Zwimpfer TA, Fereday S, Pandey A, Ariyaratne D, Jayawardana MW, Twomey L, Laumont CM, Kennedy CJ, Bolithon A, Meagher NS, Milne K, Hamilton P, Alsop J, Antoniou AC, Au-Yeung G, Beckmann MW, Berrington de Gonzalez A, Bisinotto C, Blome F, Bodelon C, Boros J, Brand AH, Carney ME, Cazorla-Jiménez A, Chiu DS, Christie EL, Chudecka-Głaz A, Coulson P, Cushing-Haugen KL, Cybulski C, Darcy KM, David C, Davidson T, Ekici AB, Elishaev E, Emons J, Engler T, Farrell R, Fischer A, García-Closas M, Gentry-Maharaj A, Ghatage P, Glasspool R, Harter P, Hartkopf AD, Hartmann A, Heikaus S, Hernandez BY, Hettiaratchi A, Heublein S, Huntsman DG, Jimenez-Linan M, Jones ME, Kang E, Kaznowska E, Kluz T, Kommoss FKF, Konecny G, Kruitwagen RFPM, Kwon J, Lambrechts D, Lee CH, Lester J, Leung SCY, Leung Y, Linder A, Lissowska J, Loverix L, Lubiński J, Mateoiu C, McNeish IA, Moubarak M, Nelson GS, Nevins N, Olawaiye AB, Olbrecht S, Orsulic S, Osorio A, Quinn CM, Mohan GR, Ray-Coquard I, Rodríguez-Antona C, Roxburgh P, Ruebner M, Salfinger SG, Samra S, Schoemaker MJ, Sinn HP, Sonke GS, Steele L, Stewart CJR, Talhouk A, Tan A, Tarney CM, Taylor SE, Van de Vijver KK, van der Aa MA, Van Gorp T, Van Nieuwenhuysen E, van-Wagensveld L, Wahner-Hendrickson AE, Walter C, Wang C, Welz J, Wentzensen N, Wilkens LR, Winham SJ, Winterhoff B, Anglesio MS, Berchuck A, Candido Dos Reis FJ, Cohen PA, Conrads TP, Crowe P, Doherty JA, Fasching PA, Fortner RT, García MJ, Gayther SA, Goodman MT, Gronwald J, Harris HR, Heitz F, Horlings HM, Karlan BY, Kelemen LE, Maxwell GL, Menon U, Modugno F, Neuhausen SL, Schildkraut JM, Staebler A, Sundfeldt K, Swerdlow AJ, Vergote I, Wu AH, Brenton JD, Pharoah PDP, Pearce CL, Pike MC, Goode EL, Ramus SJ, Köbel M, Nelson BH, DeFazio A, Friedlander ML, Bowtell DDL, Garsed DW
Dissecting and targeting SWI/SNF loss in de-differentiated endometrial carcinomas
Principal investigators: Postovit, Lynne-Marie
Keywords: Chromatin; Clonal Evolution; Dedifferentiation; Swi/Snf; Synthetic Lethality
Linking Inactivating Mutations in Chromatin Remodeling Complex Subunits to Aggressive Dedifferentiated Endometrial Carcinoma
Principal investigators: Coatham, Mackenzie L
Keywords: Arid1b; Brg1; Cellular Dedifferentiation; Dedifferentiated Endometrial Carcinoma; Epigenetics; Next Generation Sequencing; Patient Derived Xenograft Models; Stem-Cell Phenotype; Swi/Snf Chromatin Remodelling Complex; Targeted Therapy
Translational research centre to target and characterize normal and cancer stem cell niches
Principal investigators: Wuest, Frank
Keywords: Cancer, biomarkers, therapeutic targets, stem cells, microenvironment, women's cancers, translational research microenvironment, genetics, pathology
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.
Frequent collaborators
- David Huntsman and Michael Anglesio: 246 shared papers
- Michael Anglesio and Martin Koebel: 229 shared papers
- David Huntsman and Martin Koebel: 219 shared papers
- Michael Anglesio and Aline Talhouk: 213 shared papers
- Aline Talhouk and Martin Koebel: 194 shared papers
- David Huntsman and Jessica Mcalpine: 187 shared papers
- David Huntsman and Aline Talhouk: 163 shared papers
- Gregg Nelson and Martin Koebel: 117 shared papers
- Jessica Mcalpine and Aline Talhouk: 110 shared papers
- Michael Anglesio and Gregg Nelson: 92 shared papers
- David Huntsman and Gregg Nelson: 90 shared papers
- David Huntsman and Basile Tessier-Cloutier: 64 shared papers
- Jessica Mcalpine and Martin Koebel: 55 shared papers
- Martin Koebel and Brad Nelson: 50 shared papers
- Gregg Nelson and Alon Altman: 49 shared papers
- Martin Koebel and Cheng-Han Lee: 49 shared papers
- Aline Talhouk and Brad Nelson: 45 shared papers
- Jessica Mcalpine and Brad Nelson: 40 shared papers
- David Huntsman and William Foulkes: 39 shared papers
- Jessica Mcalpine and Basile Tessier-Cloutier: 38 shared papers
- Martin Koebel and Basile Tessier-Cloutier: 20 shared papers
- Jessica Mcalpine and Anna Tinker: 19 shared papers
- Mark Carey and Martin Koebel: 19 shared papers
- David Huntsman and Mark Carey: 18 shared papers
- David Huntsman and Anna Tinker: 18 shared papers
- David Huntsman and Cheng-Han Lee: 17 shared papers
- Michael Anglesio and Anna Tinker: 17 shared papers
- Gregg Nelson and Cheng-Han Lee: 16 shared papers
- Martin Koebel and Sandra Lee: 14 shared papers
- Aline Talhouk and Cheng-Han Lee: 12 shared papers
- Jessica Mcalpine and Mark Carey: 11 shared papers
- Martin Koebel and Helen Steed: 11 shared papers
- Basile Tessier-Cloutier and Cheng-Han Lee: 11 shared papers
- Michael Anglesio and Cheng-Han Lee: 10 shared papers
- Andrew Freywald and Anand Krishnan: 9 shared papers
- Jessica Mcalpine and Cheng-Han Lee: 8 shared papers
- Martin Koebel and Mary Kinloch: 8 shared papers
- David Huntsman and Helen Steed: 7 shared papers
- William Foulkes and Basile Tessier-Cloutier: 7 shared papers
- Gregg Nelson and Christa Aubrey: 7 shared papers
- Gregg Nelson and Sandra Lee: 7 shared papers
- Yangxin Fu and Helen Steed: 7 shared papers
- Yangxin Fu and Cheng-Han Lee: 7 shared papers
- Andrew Freywald and Laura Hopkins: 6 shared papers
- Mark Carey and Cheng-Han Lee: 6 shared papers
- Aline Talhouk and Mary Kinloch: 6 shared papers
- Anna Tinker and Alon Altman: 6 shared papers
- Martin Koebel and Alon Altman: 6 shared papers
- Christa Aubrey and Cheng-Han Lee: 6 shared papers
- Cheng-Han Lee and Sandra Lee: 6 shared papers
- Cheng-Han Lee and Laura Hopkins: 6 shared papers
- David Huntsman and Mary Kinloch: 5 shared papers
- Mark Carey and Yangxin Fu: 5 shared papers
- Martin Koebel and Laura Hopkins: 5 shared papers
- Helen Steed and Cheng-Han Lee: 5 shared papers
- Andrew Freywald and Martin Koebel: 4 shared papers
- Anand Krishnan and Laura Hopkins: 4 shared papers
- Alon Altman and Christa Aubrey: 4 shared papers
- William Foulkes and Martin Koebel: 3 shared papers
- Andrew Freywald and Cheng-Han Lee: 3 shared papers
- Anna Tinker and Cheng-Han Lee: 3 shared papers
- Martin Koebel and Zainab Al-Shamma: 3 shared papers
- Martin Koebel and Marjan Rouzbahman: 3 shared papers
- Cheng-Han Lee and Mary Kinloch: 3 shared papers
- David Huntsman and Marjan Rouzbahman: 2 shared papers
- William Foulkes and Cheng-Han Lee: 2 shared papers
- William Foulkes and Marjan Rouzbahman: 2 shared papers
- Mark Carey and Allan Covens: 2 shared papers
- Gregg Nelson and Zainab Al-Shamma: 2 shared papers
- Brad Nelson and Cheng-Han Lee: 2 shared papers
- Cheng-Han Lee and Zainab Al-Shamma: 2 shared papers
- Cheng-Han Lee and Marjan Rouzbahman: 2 shared papers
- David Huntsman and Allan Covens: 1 shared paper
- Andrew Freywald and Aneesh Thakur: 1 shared paper
- Anand Krishnan and Martin Koebel: 1 shared paper
- Anand Krishnan and Aneesh Thakur: 1 shared paper
- Anand Krishnan and Cheng-Han Lee: 1 shared paper
- Martin Koebel and Aneesh Thakur: 1 shared paper
- Martin Koebel and Allan Covens: 1 shared paper
- Aneesh Thakur and Cheng-Han Lee: 1 shared paper
- Allan Covens and Cheng-Han Lee: 1 shared paper
- Alon Altman and Cheng-Han Lee: 1 shared paper
- Obstetrics and Gynecology
- Obstetrics & Gynaecology Dept
- Cumming School of Medicine
- Pathology and Laboratory Medicine
- Laboratory Medicine & Pathology Dept
- Molecular Oncology
- Department of Surgery
- Other
Co-authors at University of Alberta, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Martin Koebel
Obstetrics and Gynecology
49 shared papers, latest 2026
David Huntsman
Molecular Oncology
17 shared papers, latest 2025
Gregg Nelson
Department of Surgery
16 shared papers, latest 2025
Aline Talhouk
Obstetrics and Gynecology
12 shared papers, latest 2026
Cyril Gilks
Department of Pathology and Laboratory Medicine
12 shared papers, latest 2024
Basile Tessier-Cloutier
Obstetrics and Gynecology
11 shared papers, latest 2024
Michael Anglesio
Medicine/Obstetrics & Gynecology
10 shared papers, latest 2025
Jessica Mcalpine
Obstetrics and Gynecology
8 shared papers, latest 2017
Yangxin Fu
Oncology Dept
7 shared papers, latest 2026
Laura Hopkins
Division of Oncology & Department of Gynecology
6 shared papers, latest 2026
Sandra Lee
Cumming School of Medicine
6 shared papers, latest 2024
Lynne-Marie Postovit
Oncology
6 shared papers, latest 2024
Christa Aubrey
Obstetrics & Gynaecology Dept
6 shared papers, latest 2026
Mark Carey
Obstetrics and Gynecology
6 shared papers, latest 2026
Helen Steed
Obstetrics & Gynaecology Dept
5 shared papers, latest 2024
Mary Kinloch
Pathology and Laboratory Medicine
3 shared papers, latest 2026
Andrew Freywald
Pathology and Laboratory Medicine
3 shared papers, latest 2026
Anna Tinker
Obstetrics and Gynecology
3 shared papers, latest 2026
Zainab Al-Shamma
Cumming School of Medicine
2 shared papers, latest 2024
Marjan Rouzbahman
Department of Laboratory Medicine & Pathobiology
2 shared papers, latest 2024
Brad Nelson
Biochem
2 shared papers, latest 2025
William Foulkes
Department of Human Genetics
2 shared papers, latest 2023
Brendan Dickson
Department of Laboratory Medicine & Pathobiology
1 shared papers, latest 2022
Sakinah Thiryayi
Department of Laboratory Medicine & Pathobiology
1 shared papers, latest 2022
Valerie Dube
Department of Laboratory Medicine & Pathobiology
1 shared papers, latest 2024
Arjumand Husain
Cumming School of Medicine
1 shared papers, latest 2016
Josee Ethier
Department of Medicine
1 shared papers, latest 2026
Helen MacKay
Department of Medicine
1 shared papers, latest 2026
Danielle Vicus
Department of Obstetrics & Gynaecology
1 shared papers, latest 2026
Patricia Shaw
Department of Obstetrics & Gynaecology
1 shared papers, latest 2024
Matthew Cesari
Department of Laboratory Medicine & Pathobiology
1 shared papers, latest 2024
Blaise Clarke
Department of Laboratory Medicine & Pathobiology
1 shared papers, latest 2024
Anand Krishnan
Anatomy Physiology Pharmacology
1 shared papers, latest 2026
Shuk Leung
Department of Obstetrics and Gynecology
1 shared papers, latest 2026
Aneesh Thakur
Faculty
1 shared papers, latest 2026
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Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.