This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Saskatchewan directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Epigenetic control of telomeric RNA maintains heterochromatin in telomerase-driven cancers.
Signal transduction and targeted therapy · 2026
A novel role for Neurog2 in MYCN driven neuroendocrine plasticity of prostate cancer.
Oncogene · 2025
The DRP1 receptor FIS1 is critical to the expansion of triple-negative breast cancer tumor-initiating cells.
Cancer cell international · 2025
Latest funding
- $1,105,426
Telomere-Directed Epigenetic Therapy: A Novel Approach for Treating Pancreatic Ductal Adenocarcinoma.
CIHR · 2025 · Principal investigator
- $100,000
Targeting the EGFR/EphA2 crosstalk in triple negative breast cancer
CIHR · 2023 · Nominated PI
- $59,609
Targeting mitochondrial fission machinery in tumor-initiating cells
CIHR · 2022 · Co-investigator
61 publications.
Epigenetic control of telomeric RNA maintains heterochromatin in telomerase-driven cancers.
Price JDW, Vizeacoumar FS, Abuhussein O, Maranda V, Zhang Y, Adachi H, Nguyen K, Kyrylenko L, Rangel-Pozzo A, Dong H, Gong L, Materi A, Walke P, Ganapathysamy A, Denomy C, Freywald T, Dahiya R, Elhasasna H, Saxena A, Vizeacoumar JP, Patel H, Rajamanickam K, de Oliveira DM, Lazell-Wright M, Morales AM, Aggarwal A, Xu JL, Alli N, Munhoz EP, Gao P, Salsman J, Dahiya DK, Kola NS, Gonzalez-Lopez C, Thibault P, Levin M, Dellaire G, Jette N, Groot G, Köbel M, Lee CH, Hopkins L, Krishnan A, Ahmed S, Eskiw C, Barakat KH, Thakur A, Wu Y, DePinho RA, Mai S, Yu YT, Wong JMY, Freywald A, Vizeacoumar FJ
A novel role for Neurog2 in MYCN driven neuroendocrine plasticity of prostate cancer.
Walke P, Price JDW, Vizeacoumar FS, Joseph N, Maranda V, Chowdhury B, Patel J, Zhang Y, Dong H, New L, Ganapathysamy A, Gong LH, Lazell-Wright M, Elhasasna H, Bhanumathy KK, Wu Y, Wang Y, Freywald A, Krishnan A, Vizeacoumar FJ
The DRP1 receptor FIS1 is critical to the expansion of triple-negative breast cancer tumor-initiating cells.
Katrii T, Freywald T, Estrada MG, El Zawily A, Toosi B, Vizeacoumar FS, Vizeacoumar FJ, Freywald A, Leary SC
EGFR Phosphorylates and Associates with EFNB1 to Regulate Cell Adhesion to Fibronectin.
Osornio-Hernández AI, Chartier FJM, Schuehle TL, Banerjee SL, Elowe S, Laprise P, Freywald A, Laurin M, Bisson N
Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality.
Cunningham CE, Vizeacoumar FS, Zhang Y, Kyrylenko L, Both S, Maranda V, Dong H, Price JDW, Gao P, Wagner K, Wu Y, Lazell-Wright M, Ganapathysamy A, Hari R, Bhanumathy KK, Denomy C, Saxena A, Vizeacoumar JP, Morales AM, Khan F, Mosley S, Chen A, Katrii T, Zoller BGE, Rajamanickam K, Walke P, Gong L, Patel H, Elhasasna H, Dahiya R, Abuhussein O, Dmitriev A, Freywald T, Munhoz EP, Ruppin E, Lee JS, Rox K, Koebel M, Hopkins L, Lee CH, Yadav S, Gasparoni G, Walter J, Krishnan A, Datla R, Toosi B, Baker K, Meens J, Cescon DW, Ailles L, Leary SC, Wu Y, Empting M, Kiemer AK, Freywald A, Vizeacoumar FJ
Cancer Cell's Achilles Heels: Considerations for Design of Anti-Cancer Drug Combinations.
Gahramanov V, Vizeacoumar FS, Morales AM, Bonham K, Sakharkar MK, Kumar S, Vizeacoumar FJ, Freywald A, Sherman MY
Systematic Comparison of CRISPR and shRNA Screens to Identify Essential Genes Using a Graph-Based Unsupervised Learning Model.
Ding Y, Denomy C, Freywald A, Pan Y, Vizeacoumar FJ, Vizeacoumar FS, Wu FX
Preclinical 3D model screening reveals digoxin as an effective therapy for a rare and aggressive type of endometrial cancer.
Kumar PP, Smith D, Key J, Dong H, Ganapathysamy A, Maranda V, Wong NKY, Fernandez ML, Kim H, Zhang G, Ewanowich C, Hopkins L, Freywald A, Postovit LM, Köbel M, Fu Y, Vizeacoumar FS, Vizeacoumar FJ, Carey MS, Lee CH
MEMO1 binds iron and modulates iron homeostasis in cancer cells.
Dolgova N, Uhlemann EE, Boniecki MT, Vizeacoumar FS, Ara A, Nouri P, Ralle M, Tonelli M, Abbas SA, Patry J, Elhasasna H, Freywald A, Vizeacoumar FJ, Dmitriev OY
Breast Tumor Metastasis and Its Microenvironment: It Takes Both Seed and Soil to Grow a Tumor and Target It for Treatment.
Bonni S, Brindley DN, Chamberlain MD, Daneshvar-Baghbadorani N, Freywald A, Hemmings DG, Hombach-Klonisch S, Klonisch T, Raouf A, Shemanko CS, Topolnitska D, Visser K, Vizeacoumar FJ, Wang E, Gibson SB
Telomere-Directed Epigenetic Therapy: A Novel Approach for Treating Pancreatic Ductal Adenocarcinoma.
Principal investigators: Vizeacoumar, Franco J; Freywald, Andrew
Keywords: Pancreatic Cancer; Synthetic Dosage Lethality; Telomerase
Targeting the EGFR/EphA2 crosstalk in triple negative breast cancer
Principal investigators: Freywald, Andrew; Bisson, Nicolas; Dadachova, Ekaterina; Vizeacoumar, Franco J
Keywords: Bispecific Antibody; Breast Cancer; Genome-Wide Crispr Screening; Radioconjugates
Targeting mitochondrial fission machinery in tumor-initiating cells
Principal investigators: Leary, Scot
Keywords: Breast Cancer; Oncogenes And Tumour Suppressors; Targets And Biomarkers; Translational Research
Developing combination therapies for telomerase-overexpressing clear cell carcinoma of the ovaries
Principal investigators: Maranda, Vincent
Keywords: Clear Cell Carcinoma; Mouse Models; Ovarian Cancer; Patient-Derived Xenografts; Small Molecule Inhibitors; Synthetic Lethality; Telomerase
Identification of therapeutically relevant targets in telomerase overexpressing prostate cancers
Principal investigators: Vizeacoumar, Franco J; Freywald, Andrew
Keywords: Genome-Wide Crispr And Shrna Screens; Prostate Cancer; Synthetic Dosage Lethality; Telomerase
A systematic genome wide effort to identify and validate targetable synthetic dosage lethal interactions of mitotic kinases in colorectal cancer cells
Principal investigators: Vizeacoumar, Franco J; Freywald, Andrew
Keywords: Chromosomal Instability; Crispr-Cas9-Based Target Validation; Genetic Interactions; Genomics; Pooled Shrna Screening; Synthetic Dosage Lethality
Targeting the EphA2 receptor in triple-negative breast cancer
Principal investigators: Freywald, Andrew; Price, Eric W; Vizeacoumar, Franco J
Keywords: Combination Therapy; Epha2; Molecular Imaging Agents; Synthetic Antibody; Synthetic Lethality; Triple-Negative Breast Cancer
The role of Eph receptors in the regulation of Death Receptor-induced apoptosis in T-ALL
Principal investigators: Freywald, Andrew
Keywords: Animal Models Of Leukaemia; Apoptosis; Death Receptors; Eph Receptors; Signal Transduction; T Cell Leukaemia
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Oncology
- Medical Imaging
- Medical Oncology
- Chemistry and Biochemistry
- Medicine/Oncology
- Microbiology and Immunology
- Psychiatry
- Other
Co-authors at University of Saskatchewan, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Jim Xiang
Medical Oncology
19 shared papers, latest 2021
Anand Krishnan
Faculty
4 shared papers, latest 2026
Shahid Ahmed
Medicine/Oncology
3 shared papers, latest 2026
Mohan Babu
Chemistry and Biochemistry
3 shared papers, latest 2018
Nicolas Bisson
Faculty
3 shared papers, latest 2025
Anthony Kusalik
Microbiology and Immunology
2 shared papers, latest 2022
Maruti Uppalapati
Medical Imaging
2 shared papers, latest 2019
Gary Groot
Community Health and Epidemiology
2 shared papers, latest 2026
Darrell Mousseau
Psychiatry
2 shared papers, latest 2018
Zhaolei Zhang
Terrence Donnelly Centre for Cellular and Biomolecular Research
2 shared papers, latest 2016
Kristi Baker
Oncology
1 shared papers, latest 2025
Sabine Hombach-Klonisch
Faculty
1 shared papers, latest 2024
Patrick Laprise
Faculty
1 shared papers, latest 2025
Christopher Eskiw
Biochemistry, Microbiology & Immunology
1 shared papers, latest 2026
Edwin Wang
Biochemistry and Molecular Biology
1 shared papers, latest 2024
Edana Cassol
Systems and Computer Engineering
1 shared papers, latest 2021
Aneesh Thakur
Vaccine and Infectious Disease Organization
1 shared papers, latest 2026
Yue Chen
School of Epidemiology and Public Health
1 shared papers, latest 2015
Humphrey Fonge
Medical Imaging
1 shared papers, latest 2023
Peter Siegel
Experimental Medicine
1 shared papers, latest 2018
Thomas Klonisch
Human Anatomy & Cell Science
1 shared papers, latest 2024
Ashok Kumar
Pathology and Laboratory Medicine
1 shared papers, latest 2021
Sabine Elowe
Pediatrics
1 shared papers, latest 2025
Sylvia Van Drunen Littel-van den Hurk
Faculty
1 shared papers, latest 2011
Yuzhuo Wang
Urologic Sciences
1 shared papers, latest 2025
Laurie Ailles
Department of Medical Biophysics
1 shared papers, latest 2025
Sabine Mai
Physiology
1 shared papers, latest 2026
Deborah Anderson
Oncology
1 shared papers, latest 2014
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