Grant Gordon, University of Calgary

Research

Neuroscience Astrocytes Cerebral Blood Flow Synaptic Transmission Two-Photon Optogenetics Alzheimer'S Disease Calcium Imaging

Latest papers

CD2AP at the junction of nephropathy and Alzheimer's disease.
Molecular neurodegeneration · 2025
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification.
Nature neuroscience · 2024

All 2 publications

Latest funding

Regulation of cerebral blood flow in health and Alzheimer's disease via the microbiome-brain axis
CIHR · 2025 · Supervisor
$140,000
State-dependent blood flow control by astrocytes and its dysregulation in Alzheimer's Disease
CIHR · 2024 · Nominated PI
$1,032,750
Brain Water Dynamics: New Observations, Mechanisms and Tools
NSERC · 2022 · Principal investigator
$88,700

All 12 grants and awards

2 publications.

01

CD2AP at the junction of nephropathy and Alzheimer's disease.

Vandal M, Janmaleki M, Rea I, Gunn C, Hirai S, Biernaskie J, Chun J, Gordon G, Shaw A, Sanati-Nezhad A, Pfeffer G, Calon F, Nguyen MD

Molecular neurodegeneration2025

DOI: 10.1186/s13024-025-00852-x PMID: 40462155

02

Primary cilia signaling in astrocytes mediates development and regional-specific functional specification.

Wang L, Guo Q, Acharya S, Zheng X, Huynh V, Whitmore B, Yimit A, Malhotra M, Chatterji S, Rosin N, Labit E, Chipak C, Gorzo K, Haidey J, Elliott DA, Ram T, Zhang Q, Kuipers H, Gordon G, Biernaskie J, Guo J

Nature neuroscience2024

DOI: 10.1038/s41593-024-01726-z PMID: 39103557

Regulation of cerebral blood flow in health and Alzheimer's disease via the microbiome-brain axis

SupervisorCIHR2025Canada Postdoctoral Research Award (CPRA) program

Principal investigators: Ziebarth, Tim

Keywords: Alzheimer'S Disease; Brain Blood Flow; Gut-Microbiome; In Vivo; Norepinephrine; Two-Photon Microscopy

$140,000

State-dependent blood flow control by astrocytes and its dysregulation in Alzheimer's Disease

Nominated PICIHR2024Project Grant

Principal investigators: Gordon, Grant R

Keywords: Alzheimer'S Disease; Astrocytes; Calcium Imaging; Cerebral Blood Flow; In Vivo; Locomotion; Sleep; Synaptic Transmission; Two-Photon; Vascular Imaging

$1,032,750

Brain Water Dynamics: New Observations, Mechanisms and Tools

Principal investigatorNSERC2022Discovery Grants Program - Individual

Principal investigators: Gordon, Grant

Keywords: astrocytes; cerebral spinal fluid; glymphatic; in vivo; mice; neurons; neuroscience; optical imaging; short-wave infrared; water

$88,700

Health Research Training to Address Vascular Contributions to Cognitive Decline: the Vascular Training (VAST) Platform

Co-investigatorCIHR2021Tr. Grant: Health Research Training Platform - Vascular Cognitive Impairment

Principal investigators: Smith, Eric E; Badhwar, Amanpreet; Mazerolle, Erin L; Stefanovic, Bojana

Keywords: Vascular Cognitive Impairment

$2,380,292

Aberrant glia-mediated synapse pruning in the pathophysiology of chronic stress

SupervisorCIHR2021Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Peringod, Govind

Keywords: Co-Labeling; Confocal Microscopy; Contextual Fear Conditioning; Corticosterone; Depression; Gene Knockout; Glia; Learning And Memory; Stress; Synapse Engulfment

$105,000

Bioenergetic control of plasticity by astrocytes in stress

Nominated PICIHR2020Project Grant

Principal investigators: Gordon, Grant R

Keywords: Neuroscience

$883,576

BRAIN CREATE: Interdisciplinary Training Program for New Neurotechnologies

Co-investigatorNSERC2019Collaborative Research and Training Experience

Principal investigators: Poulin, Marc

$1,649,235

The type 1 IP3 receptor as a critical regulator of cerebrovascular function

Co-investigatorCIHR2017Project Grant

Principal investigators: Braun, Andrew P

Keywords: Blood Flow; Calcium Dynamics; Cerebral Arteries; Cerebrovascular Function; Gain-Of-Function Mutation; Ip3 Receptors

$589,052

CRC Tier 2

Nominated PICIHR2016Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Gordon, Grant R

Keywords: Crc

$500,000

Optical Deconstruction of the Neuro-vascular Unit: Delineating the Unitary Building Block of the Central Nervous System

Nominated PICIHR2015Foundation Grant

Principal investigators: Gordon, Grant R

Keywords: Astrocyte; Cerebral Blood Flow; Neuroscience; Neurovascular Unit; Optogenetics; Synaptic Transmission; Two-Photon

$988,024

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Physiology and Pharmacology
Biomedical Engineering
Neurosciences
Clinical Neurosciences
Clinical Neurological Sciences
Cell Biology and Anatomy
Medicine

Co-authors at University of Calgary, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Jiami Guo

Cell Biology and Anatomy

1 shared papers, latest 2024

Amir Sanati Nezhad

Biomedical Engineering

1 shared papers, latest 2025

Justin Chun

Medicine

1 shared papers, latest 2025

Gerald Pfeffer

Clinical Neurosciences

1 shared papers, latest 2025

Hedwich Kuipers

Clinical Neurological Sciences

1 shared papers, latest 2024

Frédéric Calon

Neurosciences

1 shared papers, latest 2025

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2024

Subject: Prospective PhD student: Neuroscience Dear Professor Gordon, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "CD2AP at the junction of nephropathy and Alzheimer's disease." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "State-dependent blood flow control by astrocytes and its dysregulation in Alzheimer's Disease" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]