Jaideep Bains, University of Calgary

Research

Electrophysiology Stress Synapse Hypothalamus Plasticity Gaba Optogenetics Buffering

Latest papers

Biofilm exopolysaccharides alter sensory-neuron-mediated sickness during lung infection.
Cell · 2024
Novel Psilocin Prodrugs with Altered Pharmacological Properties as Candidate Therapies for Treatment-Resistant Anxiety Disorders.
Journal of medicinal chemistry · 2024
A holistic gene-network approach linking stressor heterogeneity to resilience and susceptibility.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022 · senior author

All 8 publications

Latest funding

Oxytocinergic regulation of bi-directional social contagion and social buffering during stress recall
CIHR · 2023 · Supervisor
$123,750
Social touch and stress buffering
CIHR · 2022 · Nominated PI
$1,040,400
Hypothalamic CRH neurons and stress anticipation
CIHR · 2022 · Nominated PI
$1,051,876

All 11 grants and awards

8 publications.

01

Biofilm exopolysaccharides alter sensory-neuron-mediated sickness during lung infection.

Granton E, Brown L, Defaye M, Moazen P, Almblad H, Randall TE, Rich JD, Geppert A, Abdullah NS, Hassanabad MF, Hiroki CH, Farias R, Nguyen AP, Schubert C, Lou Y, Andonegui G, Iftinca M, Raju D, Vargas MA, Howell PL, Füzesi T, Bains J, Kurrasch D, Harrison JJ, Altier C, Yipp BG

Cell2024

DOI: 10.1016/j.cell.2024.03.001 PMID: 38518773

02

Novel Psilocin Prodrugs with Altered Pharmacological Properties as Candidate Therapies for Treatment-Resistant Anxiety Disorders.

Raithatha SA, Hagel JM, Matinkhoo K, Yu L, Press D, Cook SG, Sharma G, Dhananjaya D, Jensen G, Lee JB, Cai C, Gallant J, Bains J, Tucker JE, Facchini PJ

Journal of medicinal chemistry2024

DOI: 10.1021/acs.jmedchem.3c01225 PMID: 37983270

03

A holistic gene-network approach linking stressor heterogeneity to resilience and susceptibility.

Sterley TL, Bains J

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2022Senior author

DOI: 10.1038/s41386-022-01267-8 PMID: 35121831

04

Behavioral Deficits in Mice with Postnatal Disruption of Ndel1 in Forebrain Excitatory Neurons: Implications for Epilepsy and Neuropsychiatric Disorders.

Gavrilovici C, Jiang Y, Kiroski I, Sterley TL, Vandal M, Bains J, Park SK, Rho JM, Teskey GC, Nguyen MD

Cerebral cortex communications2021

DOI: 10.1093/texcom/tgaa096 PMID: 33615226

05

A Neuroethics Backbone for the Evolving Canadian Brain Research Strategy.

Illes J, Weiss S, Bains J, Chandler JA, Conrod P, De Koninck Y, Fellows LK, Groetzinger D, Racine E, Robillard JM, Sokolowski MB

Neuron2019

DOI: 10.1016/j.neuron.2018.12.021 PMID: 30731060

06

Open-source, cost-effective system for low-light in vivo fiber photometry.

Simone K, Füzesi T, Rosenegger D, Bains J, Murari K

Neurophotonics2018

DOI: 10.1117/1.nph.5.2.025006 PMID: 29687037

07

CB1 Receptor Signaling in the Brain: Extracting Specificity from Ubiquity.

Busquets-Garcia A, Bains J, Marsicano G

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2018

DOI: 10.1038/npp.2017.206 PMID: 28862250

08

Neuromodulators, stress and plasticity: a role for endocannabinoid signalling.

Senst L, Bains J

The Journal of experimental biology2014Senior author

DOI: 10.1242/jeb.089730 PMID: 24353209

Oxytocinergic regulation of bi-directional social contagion and social buffering during stress recall

SupervisorCIHR2023CIHR REDI Early Career Transition Award - Brain Health and Cognitive Impairment

Principal investigators: Akinrinade, Ibukun

Keywords: Buffering; Contagion; Corticotrophin Releasing Hormone; Hypothalamus; Lateral Septum; Neural Circuit; Oxytocin; Paraventricular Nucleus; Social Behaviour; Stress

$123,750

Social touch and stress buffering

Nominated PICIHR2022Project Grant

Principal investigators: Bains, Jaideep S

Keywords: Buffering; Crh; Electrophysiology; Hypothalamus; Oxytocin; Patch Clamp; Stress; Synapse

$1,040,400

Hypothalamic CRH neurons and stress anticipation

Nominated PICIHR2022Project Grant

Principal investigators: Bains, Jaideep S

Keywords: Anticipation; Electrophysiology; Endocrine; Imaging; Plasticity; Ptsd; Stress; Synapse

$1,051,876

Probing brain network dynamics in freely behaving animals

Principal investigatorNSERC2021Research Tools and Instruments

Principal investigators: Bains, Jaideep

$150,000

Aberrant glia-mediated synapse pruning in the pathophysiology of chronic stress

SupervisorCIHR2021Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Peringod, Govind

Keywords: Co-Labeling; Confocal Microscopy; Contextual Fear Conditioning; Corticosterone; Depression; Gene Knockout; Glia; Learning And Memory; Stress; Synapse Engulfment

$105,000

Hypothalamic CRH neurons and the control of innate behaviour

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Bains, Jaideep

$282,000

Brain circuitry underlying social buffering after stress

SupervisorCIHR2018Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Loewen, Spencer P

Keywords: Electrophysiology; Hypothalamus; Metaplasticity; Neural Circuit; Optogenetics; Short-Term Potentiation; Social Buffering; Stress; Synapse; Vasopressin

$105,000

Stress hyper-reactivity and GABA plasticity

Nominated PICIHR2016Project Grant

Principal investigators: Bains, Jaideep S

Keywords: Chloride; Electrophysiology; Gaba; Hypothalamus; Plasticity; Stress; Synapse

$986,205

Synapses, Circuits and Stress

Nominated PICIHR2015Foundation Grant

Principal investigators: Bains, Jaideep S

Keywords: Electrophysiology; Gaba; Glia; Glutamate; Neural Circuit; Neuroscience; Optogenetics; Stress; Synaptic Plasticity

$2,558,224

GABA, metaplasticity and stress

Nominated PICIHR2012Operating Grant

Principal investigators: Bains, Jaideep S

Keywords: Electrophysiology; Gaba; Hypothalamus; Metaplasticity; Mglur; Noradrenaline; Optogenetics; Plasticity; Stress; Synapse

$834,815

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Physiology and Pharmacology
Medical Genetics
Medicine/Neurology
Psychiatrie et addictologie
Cell Biology and Anatomy
Other

Co-authors at University of Calgary, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Patricia Conrod

Psychiatrie et addictologie

1 shared papers, latest 2019

Judy Illes

Medicine/Neurology

1 shared papers, latest 2019

Yves De Koninck

Faculty

1 shared papers, latest 2019

Samuel Weiss

Cell Biology and Anatomy

1 shared papers, latest 2019

Jaideep Bains

Faculty

1 shared papers, latest 2024

Christophe Altier

Physiology and Pharmacology

1 shared papers, latest 2024

Deborah Kurrasch

Medical Genetics

1 shared papers, latest 2024

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2022

Subject: Prospective PhD student: Electrophysiology Dear Professor Bains, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Biofilm exopolysaccharides alter sensory-neuron-mediated sickness during lung infection." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Social touch and stress buffering" (2022), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]