Faculty profile

Samuel Weiss

ResearcherCell Biology and AnatomyUniversity of Calgary

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Calgary directory, so their courses may be missing. Find their university profile.

Samuel Weiss

Researcher

Cell Biology and Anatomy

Health Sciences

University of Calgary

Calgary, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
6 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 1 research grant (1 CIHR), most recently in 2016.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

182

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Brain Tumour Stem Cells Cancer Stem Cells Experimental Therapeutics Glioblastoma Glutamine Dependence Glycolysis Metabolism Stat3 Signalling

Latest papers

The COP9 signalosome subunit CSN1 regulates glioblastoma stem cell growth.
PloS one · 2026 · senior author
Glioblastoma stem cell growth requires DOT1L-MED23 control of enhancer accessibility.
Cell reports · 2026 · senior author
IGF2 supports glioblastoma growth and immune evasion through a combination of tumor cell-intrinsic and -extrinsic mechanisms.
Neuro-oncology advances · 2026

All 59 publications

Latest funding

Targeting a unique glutamine dependence in brain tumour stem cells: A novel therapeutic option for GBM
CIHR · 2016 · Nominated PI
$757,352
Canadian Stroke Network (2006 Renewal Competition)
NSERC · 2013 · Co-investigator
$500,000
NSERC CREATE in Biological information processing: From genome to systems level
NSERC · 2012 · Co-investigator
$1,650,000

All 8 grants and awards

59 publications.

The COP9 signalosome subunit CSN1 regulates glioblastoma stem cell growth.

Assaf S, Heemskerk K, Hao X, Luchman HA, Weiss S

PloS one2026Senior author

DOI: 10.1371/journal.pone.0358568 PMID: 42752691

Glioblastoma stem cell growth requires DOT1L-MED23 control of enhancer accessibility.

Assaf S, Bozek DA, Heemskerk K, Banks A, MacLeod G, Bahia RK, Cutts E, Johnston MJ, Cseh O, Angers S, Nikolic A, Gallo M, Luchman HA, Weiss S

Cell reports2026Senior author

DOI: 10.1016/j.celrep.2026.117647 PMID: 42397736

IGF2 supports glioblastoma growth and immune evasion through a combination of tumor cell-intrinsic and -extrinsic mechanisms.

Heemskerk KM, Assaf S, Hao X, Snelling S, Meode M, Hassam R, Cseh O, Kala S, Pemberton J, Chan JA, Cairncross JG, Forsyth P, Yong VW, Mirzaei R, Weiss S, Zemp FJ, Luchman HA

Neuro-oncology advances2026

DOI: 10.1093/noajnl/vdaf226 PMID: 41568176

Exploiting metabolic vulnerability in glioblastoma using a brain-penetrant drug with a safe profile.

Burban A, Tessier C, Larroquette M, Guyon J, Lubiato C, Pinglaut M, Toujas M, Galvis J, Dartigues B, Georget E, Luchman HA, Weiss S, Cappellen D, Nicot N, Klink B, Nikolski M, Brisson L, Mathivet T, Bikfalvi A, Daubon T, Sharanek A

EMBO molecular medicine2025

DOI: 10.1038/s44321-025-00195-6 PMID: 39901019

Epigenetic and molecular coordination between HDAC2 and SMAD3-SKI regulates essential brain tumour stem cell characteristics.

Bahia RK, Hao X, Hassam R, Cseh O, Bozek DA, Luchman HA, Weiss S

Nature communications2023Senior author

DOI: 10.1038/s41467-023-40776-y PMID: 37598220

Chemical genomics reveals targetable programs of human cancers rooted in pluripotency

Orlando L, Benoit YD, Reid JC, Nakanishi M, Boyd AL, García-Rodriguez JL, Tanasijevic B, Doyle MS, Luchman A, Restall IJ

Cell Chemical Biology20238 citations

DOI: 10.1016/j.chembiol.2023.06.004

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.

Richards LM, Whitley OKN, MacLeod G, Cavalli FMG, Coutinho FJ, Jaramillo JE, Svergun N, Riverin M, Croucher DC, Kushida M, Yu K, Guilhamon P, Rastegar N, Ahmadi M, Bhatti JK, Bozek DA, Li N, Lee L, Che C, Luis E, Park NI, Xu Z, Ketela T, Moore RA, Marra MA, Spears J, Cusimano MD, Das S, Bernstein M, Haibe-Kains B, Lupien M, Luchman HA, Weiss S, Angers S, Dirks PB, Bader GD, Pugh TJ

Nature cancer2021

DOI: 10.1038/s43018-020-00154-9 PMID: 35122077

PRMT5 inhibition disrupts splicing and stemness in glioblastoma.

Sachamitr P, Ho JC, Ciamponi FE, Ba-Alawi W, Coutinho FJ, Guilhamon P, Kushida MM, Cavalli FMG, Lee L, Rastegar N, Vu V, Sánchez-Osuna M, Coulombe-Huntington J, Kanshin E, Whetstone H, Durand M, Thibault P, Hart K, Mangos M, Veyhl J, Chen W, Tran N, Duong BC, Aman AM, Che X, Lan X, Whitley O, Zaslaver O, Barsyte-Lovejoy D, Richards LM, Restall I, Caudy A, Röst HL, Bonday ZQ, Bernstein M, Das S, Cusimano MD, Spears J, Bader GD, Pugh TJ, Tyers M, Lupien M, Haibe-Kains B, Artee Luchman H, Weiss S, Massirer KB, Prinos P, Arrowsmith CH, Dirks PB

Nature communications2021

DOI: 10.1038/s41467-021-21204-5 PMID: 33579912

Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival.

Guilhamon P, Chesnelong C, Kushida MM, Nikolic A, Singhal D, MacLeod G, Madani Tonekaboni SA, Cavalli FM, Arlidge C, Rajakulendran N, Rastegar N, Hao X, Hassam R, Smith LJ, Whetstone H, Coutinho FJ, Nadorp B, Ellestad KI, Luchman HA, Chan JA, Shoichet MS, Taylor MD, Haibe-Kains B, Weiss S, Angers S, Gallo M, Dirks PB, Lupien M

eLife2021

DOI: 10.7554/elife.64090 PMID: 33427645

Brain Tumor Stem Cell Dependence on Glutaminase Reveals a Metabolic Vulnerability through the Amino Acid Deprivation Response Pathway.

Restall IJ, Cseh O, Richards LM, Pugh TJ, Luchman HA, Weiss S

Cancer research2020Senior author

DOI: 10.1158/0008-5472.can-19-3923 PMID: 33106333

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Samuel Weiss

Research

Latest papers

Latest funding

The COP9 signalosome subunit CSN1 regulates glioblastoma stem cell growth.

Glioblastoma stem cell growth requires DOT1L-MED23 control of enhancer accessibility.

IGF2 supports glioblastoma growth and immune evasion through a combination of tumor cell-intrinsic and -extrinsic mechanisms.

Exploiting metabolic vulnerability in glioblastoma using a brain-penetrant drug with a safe profile.

Epigenetic and molecular coordination between HDAC2 and SMAD3-SKI regulates essential brain tumour stem cell characteristics.

Chemical genomics reveals targetable programs of human cancers rooted in pluripotency

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.

PRMT5 inhibition disrupts splicing and stemness in glioblastoma.

Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival.

Brain Tumor Stem Cell Dependence on Glutaminase Reveals a Metabolic Vulnerability through the Amino Acid Deprivation Response Pathway.

Targeting a unique glutamine dependence in brain tumour stem cells: A novel therapeutic option for GBM

Canadian Stroke Network (2006 Renewal Competition)

NSERC CREATE in Biological information processing: From genome to systems level

Stem Cell Network/Réseau de cellules souches

Canadian Stroke Network (2006 Renewal Competition)

Stem Cell Network/Réseau de cellules souches

Canadian Network for Vaccines and Immunotherapeutics of Cancer and Chronic Viral Diseases (CANVAC) (2006 Renewal Competition)

Canadian Network for Vaccines and Immunotherapeutics of Cancer and Chronic Viral Diseases (CANVAC)

Frequent collaborators

Stephane Angers

Mathieu Lupien

Ahmed Aman

Gregory Cairncross

Benjamin Haibe-Kains

Mark Bernstein

Sunit Das

Sheila Singh

Arezu Jahani-Asl

Lesley Seymour

Dalia Barsyte-Lovejoy

Marco Gallo

David Uehling

Vijay Ramaswamy

Livia Garzia

Patricia Conrod

Judy Illes

Amy Caudy

Yves De Koninck

Jennifer Chan

Larry Fliegel

Daniel Schramek

Arezu Jahani-Asl

Mick Bhatia

Karen Kopciuk

Stefano Stifani

Nada Jabado

Carol Schuurmans

Jaideep Bains