Laura Curiel, University of Calgary

Research

Animal devices Device design High intensity focused ultrasound Imaging guidance Molecule delivery Preclinical devices Ultrasound imaging Ultrasound therapy

Latest papers

Ultrasound imaging using single-element biaxial beamforming.
Journal of medical imaging (Bellingham, Wash.) · 2026
Predegenerating donor nerve for grafting using focused ultrasound neurotomy.
Scientific reports · 2025
Biaxial ultrasound driving technique for small animal blood-brain barrier opening.
Physics in medicine and biology · 2023

All 21 publications

Latest funding

Advancing Research through Enhanced Design of Focused Ultrasound Animal Devices
NSERC · 2020 · Principal investigator
$195,000
Increasing Efficiency of Focused Ultrasound Transducer Applications
NSERC · 2017 · Principal investigator
$120,372
High intensity focused ultrasound and newly engineered single domain antibodies for non-invasive treatment of humanpapillomavirus-related cervical cancer
NSERC · 2015 · Co-investigator
$226,870

All 9 grants and awards

21 publications.

01

Ultrasound imaging using single-element biaxial beamforming.

Meulenbroek N, Curiel L, Waspe A, Pichardo S

Journal of medical imaging (Bellingham, Wash.)2026

DOI: 10.1117/1.jmi.13.1.017001 PMID: 41445720

02

Predegenerating donor nerve for grafting using focused ultrasound neurotomy.

Chu TH, Lasaleta N, Li S, McConnachie A, Molina L, Alzahrani S, Curiel L, Pichardo S, Midha R

Scientific reports2025

DOI: 10.1038/s41598-025-00316-8 PMID: 40320399

03

Biaxial ultrasound driving technique for small animal blood-brain barrier opening.

Pellow C, Li S, Delgado S, Pike GB, Curiel L, Pichardo S

Physics in medicine and biology2023

DOI: 10.1088/1361-6560/acf2e3 PMID: 37607563

04

Higher harmonics dynamic focalization in single-element ring transducers using biaxial driving.

Delgado S, Curiel L, Li S, Pichardo S

Ultrasonics2023

DOI: 10.1016/j.ultras.2023.107051 PMID: 37276698

05

Comparing Phantom and Animal Metrics Applied in the Determination of Focused Ultrasound Stable and Inertial Cavitation Levels.

Smith MR, Khan S, Curiel L

Ultrasound in medicine & biology2023Senior author

DOI: 10.1016/j.ultrasmedbio.2022.12.012 PMID: 36732151

06

Aptamer-Functionalized Microbubbles Targeted to P-selectin for Ultrasound Molecular Imaging of Murine Bowel Inflammation.

Goncin U, Curiel L, Geyer CR, Machtaler S

Molecular imaging and biology2023

DOI: 10.1007/s11307-022-01755-9 PMID: 35851673

07

Investigation of hardware and software techniques to enhance the characteristics of focused ultrasound (FUS) spectra.

Smith M, Khan S, Curiel L

Physics in medicine and biology2022Senior author

DOI: 10.1088/1361-6560/ac7374 PMID: 35613564

08

Rapid Copper-free Click Conjugation to Lipid-Shelled Microbubbles for Ultrasound Molecular Imaging of Murine Bowel Inflammation.

Goncin U, Bernhard W, Curiel L, Geyer CR, Machtaler S

Bioconjugate chemistry2022

DOI: 10.1021/acs.bioconjchem.2c00104 PMID: 35427123

09

Breast tissue mimicking phantoms for combined ultrasound and microwave imaging.

Li S, Fear E, Curiel L

Physics in medicine and biology2021Senior author

DOI: 10.1088/1361-6560/ac3d18 PMID: 34818636

10

Steering single-element lead zirconate titanate ultrasound transducers using biaxial driving.

Delgado S, Curiel L, Pichardo S

Ultrasonics2021

DOI: 10.1016/j.ultras.2020.106241 PMID: 32916381

Advancing Research through Enhanced Design of Focused Ultrasound Animal Devices

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Curiel, Laura

Keywords: high intensity focused ultrasound; imaging guidance; preclinical devices; animal devices; molecule delivery; ultrasound therapy; device design; ultrasound imaging

$195,000

Increasing Efficiency of Focused Ultrasound Transducer Applications

Principal investigatorNSERC2017Research Tools and Instruments

Principal investigators: Curiel, Laura

$120,372

High intensity focused ultrasound and newly engineered single domain antibodies for non-invasive treatment of humanpapillomavirus-related cervical cancer

Co-investigatorNSERC2015Collaborative Health Research Projects

Principal investigators: Zehbe, Ingeborg

$226,870

Positron emission tomography-guided focused ultrasound platform for experimental molecule delivery

Principal investigatorNSERC2015Engage Grants Program

Principal investigators: Curiel, Laura

$24,200

Enhancing high intensity focused ultrasound molecule delivery using molecular imaging

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: Curiel, Laura

$94,999

High intensity focused ultrasound and newly engineered single domain antibodies for non-invasive treatment of human papillomavirus-related cervical cancer

Principal investigatorCIHR2014Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Zehbe, Ingeborg; Curiel, Laura

Keywords: Caski Cells; Cervical Cancer; Delivery Of Single Domain Antibodies Against E6; High Intensity Focused Ultrasound; Hpv16 E6 Protein; Human Papillomavirus Type 16 (Hpv16); Non-Invasive Cancer Therapy; Nude Mouse Model; Sonoporation And Microbubbles

$226,870

Improving research activity on novel minimally invasive procedures for cancer treatment in Northwestern Ontario

Nominated PICIHR2014Planning and Dissemination Grant - Institute Community Support

Principal investigators: Curiel, Laura

Keywords: Cancer Interventions; Improving Research Participation; Magnetic Imaging Guided Linear Accelerator; Magnetic Resonance Guided High Intensity Focused Ultrasound; Minimally Invasive Cancer Treatment

$10,000

NSERC CREATE in Medical Imaging Detector Technologies

Co-investigatorNSERC2012Collaborative Research and Training Experience

Principal investigators: Reznik, Alla

$1,279,342

Novel imaging guidance for high intensity focused ultrasound

Principal investigatorNSERC2010Discovery Grants Program - Individual

Principal investigators: Curiel, Laura

$155,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Electrical and Computer Engineering
Biology
Medical Biophysics
Medical Imaging
Neurosciences and Mental Health
Electrical Engineering
Pathology and Laboratory Medicine
Other

Co-authors at University of Calgary, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Ingeborg Zehbe

Biology

3 shared papers, latest 2015

Kullervo Hynynen

Medical Biophysics

2 shared papers, latest 2017

Steven Machtaler

Medical Imaging

2 shared papers, latest 2023

Elise Fear

Electrical Engineering

1 shared papers, latest 2021

Adam Waspe

Neurosciences and Mental Health

1 shared papers, latest 2026

Kunyan Zhang

Pathology and Laboratory Medicine

1 shared papers, latest 2014

Oleg Rubel

Materials Science and Engineering

1 shared papers, latest 2015

Rajiv Midha

Clinical Neurosciences

1 shared papers, latest 2025

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2020

Subject: Prospective PhD student: Animal devices Dear Professor Curiel, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Ultrasound imaging using single-element biaxial beamforming." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Advancing Research through Enhanced Design of Focused Ultrasound Animal Devices" (2020), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]