Faculty profile
Damon Poburko
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Simon Fraser University directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Loss-of-function mitochondrial DNA polymerase gamma variants cause vascular smooth muscle cells to secrete a diffusible mitogenic factor.
Frontiers in physiology · 2024 · senior author
Emerging methods for and novel insights gained by absolute quantification of mitochondrial DNA copy number and its clinical applications.
Pharmacology & therapeutics · 2022 · senior author
A differentiated Ca2+ signalling phenotype has minimal impact on myocardin expression in an automated differentiation assay using A7r5 cells.
Cell calcium · 2021 · senior author
Latest funding
- $192,000
Cellular and Molecular Physiology of Sympathetic Innervation of Vascular Smooth Muscle
NSERC · 2019 · Principal investigator
- $126,802
Digital polymerase chain reaction (PCR) and high-capacity multiplex PCR for next-generation sequencing
NSERC · 2015 · Co-investigator
- $186,000
Cellular and Molecular Physiology of Sympathetic Innervation of Vascular Smooth Muscle
NSERC · 2012 · Principal investigator
10 publications.
Loss-of-function mitochondrial DNA polymerase gamma variants cause vascular smooth muscle cells to secrete a diffusible mitogenic factor.
Rothwell S, Ng I, Shalchy-Tabrizi S, Kalinowski P, Taha OM, Paris I, Baniqued A, Lin L, Mezei MM, Lehman A, Julian LM, Poburko D
Emerging methods for and novel insights gained by absolute quantification of mitochondrial DNA copy number and its clinical applications.
Li B, Kalinowski P, Kim B, Pauls AD, Poburko D
A differentiated Ca2+ signalling phenotype has minimal impact on myocardin expression in an automated differentiation assay using A7r5 cells.
Kim B, Molina R, Jensen G, Poburko D
Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity.
Ghovanloo MR, Choudhury K, Bandaru TS, Fouda MA, Rayani K, Rusinova R, Phaterpekar T, Nelkenbrecher K, Watkins AR, Poburko D, Thewalt J, Andersen OS, Delemotte L, Goodchild SJ, Ruben PC
High rate of hypertension in patients with m.3243A>G MELAS mutations and POLG variants.
Pauls AD, Sandhu V, Young D, Nevay DL, Yeung DF, Sirrs S, Tsang MY, Tsang TSM, Lehman A, Mezei MM, Poburko D
Case studies in neuroscience: a novel amino acid duplication in the NH2-terminus of the brain sodium channel NaV1.1 underlying Dravet syndrome.
Angus M, Peters CH, Poburko D, Brimble E, Spelbrink EM, Ruben PC
VNUT and VMAT2 segregate within sympathetic varicosities and localize near preferred Cav2 isoforms in the rat tail artery.
Mojard Kalkhoran S, Chow SHJ, Walia JS, Gershome C, Saraev N, Kim B, Poburko D
Droplet digital PCR shows the D-Loop to be an error prone locus for mitochondrial DNA copy number determination.
Li B, Kaushik S, Kalinowski P, Kim B, Gershome C, Ching J, Poburko D
Loss-of-Function and Gain-of-Function Mutations in KCNQ5 Cause Intellectual Disability or Epileptic Encephalopathy.
Lehman A, Thouta S, Mancini GMS, Naidu S, van Slegtenhorst M, McWalter K, Person R, Mwenifumbo J, Salvarinova R, CAUSES Study, EPGEN Study, Guella I, McKenzie MB, Datta A, Connolly MB, Kalkhoran SM, Poburko D, Friedman JM, Farrer MJ, Demos M, Desai S, Claydon T
Regulation of the mitochondrial proton gradient by cytosolic Ca²⁺ signals.
Poburko D, Demaurex N
Cellular and Molecular Physiology of Sympathetic Innervation of Vascular Smooth Muscle
Principal investigators: Poburko, Damon
Keywords: microscopy; mitochondria; molecular biology; neurotransmitter co-release; smooth muscle; sympathetic nerves; synaptic physiology
Digital polymerase chain reaction (PCR) and high-capacity multiplex PCR for next-generation sequencing
Principal investigators: Morin, Ryan
Cellular and Molecular Physiology of Sympathetic Innervation of Vascular Smooth Muscle
Principal investigators: Poburko, Damon
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Thomas Claydon and Damon Poburko: 1 shared paper
- Jenifer Thewalt and Damon Poburko: 1 shared paper
- Biomedical Physiology & Kinesiology
- Molecular Biology and Biochemistry
- Biomedical Physiology and Kinesiology
Co-authors at Simon Fraser University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.