Faculty profile
Andrew Weng
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Research
Latest papers
MAGIC-DR: An interpretable machine-learning guided approach for acute myeloid leukemia measurable residual disease analysis.
Cytometry. Part B, Clinical cytometry · 2024
Integrated single cell analysis reveals co-evolution of malignant B cells and tumor micro-environment in transformed follicular lymphoma.
Cancer cell · 2024
Comprehensive immune profiling of patients with advanced urothelial or renal cell carcinoma receiving immune checkpoint blockade.
Frontiers in oncology · 2022
Latest funding
- $448,770
Unveiling the Epigenetic Landscape and Therapeutic Implications of Epigenetic Modifiers in Human T-cell Leukemia Initiation and Progression
CIHR · 2023 · Nominated PI
- $317,475
Machine Learning for Flow Cytometry Clinical Data and Trial Analysis
CIHR · 2019 · Principal investigator
- $105,000
High-throughput RNA interference screening reveals epigenetic modifier dependencies in a synthetic model of human T-cell acute lymphoblastic leukemia
CIHR · 2017 · Supervisor
6 publications.
MAGIC-DR: An interpretable machine-learning guided approach for acute myeloid leukemia measurable residual disease analysis.
Shopsowitz K, Lofroth J, Chan G, Kim J, Rana M, Brinkman R, Weng A, Medvedev N, Wang X
Integrated single cell analysis reveals co-evolution of malignant B cells and tumor micro-environment in transformed follicular lymphoma.
Sarkozy C, Wu S, Takata K, Aoki T, Neriah SB, Milne K, Goodyear T, Strong C, Rastogi T, Hilton LK, Lai D, Sehn LH, Farinha P, Nelson BH, Weng A, Marra M, Scott DW, Craig JW, Steidl C, Roth A
Comprehensive immune profiling of patients with advanced urothelial or renal cell carcinoma receiving immune checkpoint blockade.
Lavoie JM, Baichoo P, Chavez E, Nappi L, Khalaf D, Kollmannsberger CK, Chi KN, Weng A, Steidl C, Eigl BJ, Nissen M
Avadomide monotherapy in relapsed/refractory DLBCL: safety, efficacy, and a predictive gene classifier.
Carpio C, Bouabdallah R, Ysebaert L, Sancho JM, Salles G, Cordoba R, Pinto A, Gharibo M, Rasco D, Panizo C, Lopez-Martin JA, Santoro A, Salar A, Damian S, Martin A, Verhoef G, Van den Neste E, Wang M, Couto S, Carrancio S, Weng A, Wang X, Schmitz F, Wei X, Hege K, Trotter MWB, Risueño A, Buchholz TJ, Hagner PR, Gandhi AK, Pourdehnad M, Ribrag V
Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal.
Heuser M, Sly LM, Argiropoulos B, Kuchenbauer F, Lai C, Weng A, Leung M, Lin G, Brookes C, Fung S, Valk PJ, Delwel R, Löwenberg B, Krystal G, Humphries RK
A pipeline for automated analysis of flow cytometry data: preliminary results on lymphoma sub-type diagnosis.
Bashashati A, Lo K, Gottardo R, Gascoyne RD, Weng A, Brinkman R
Unveiling the Epigenetic Landscape and Therapeutic Implications of Epigenetic Modifiers in Human T-cell Leukemia Initiation and Progression
Principal investigators: Weng, Andrew P
Keywords: Carcinogenesis; Crispr-Cas Systems; Epigenomics; Guide; Leukemia; Rna; Single-Cell Gene Expression Analysis; T-Cell
Machine Learning for Flow Cytometry Clinical Data and Trial Analysis
Principal investigators: Brinkman, Ryan; Weng, Andrew P
Keywords: Automated Analysis; Big Data; Biomarker Discovery; Canjcer; Diagnosis; Flow Cytometry; Immunology; Immunotherapy; Machine Learning
High-throughput RNA interference screening reveals epigenetic modifier dependencies in a synthetic model of human T-cell acute lymphoblastic leukemia
Principal investigators: Wong, Alana R
Keywords: Epigenetics; Leukaemia; Rna Interference Screen; Small Hairpin Rna; Targeted Therapy
De-constructing Oncogenic Effectors in a Synthetic Model of Human T-cell Acute Lymphoblastic Leukemia
Principal investigators: Sun, Chong
Keywords: Cancer; Immunodeficient Mice; In Vitro Cultures; Leukemia; Leukemogenesis; Synthetic Models; T-Cells
The pathogenic and clinical significance of somatic TMEM30A mutations in diffuse large B cell lymphoma
Principal investigators: Steidl, Christian
Keywords: Biomarkers; Genomics; Lymphoma; Microenvironment; Pathogenesis; Somatic Mutations
Resolution of inter- and intra-tumoral heterogeneity in DLBCL using mass cytometry
Principal investigators: Weng, Andrew P
Keywords: Biomarker; Cytof; Dlbcl; Dna Mutation; Flow Cytometry; Immune Profiling; Intratumoral Heterogeneity; Lymphoma; Mass Cytometry; Rna-Seq
Mediators and targets of Wnt signaling in T-ALL stem cells
Principal investigators: Weng, Andrew P
Keywords: Beta-Catenin; Cancer Stem Cells; Chip-Seq; Leukemia; Mouse Models; Patient-Derived Xenografts; Rna-Seq; T-All; Tcf/Lef; Wnt Signaling
The biology and clinical significance of the tumour microenvironment in B cell lymphomas
Principal investigators: Steidl, Christian
Keywords: Biomarker; Cancer; Genomics; Immune Biology; Lymphoma; Microenvironment; Molecular Genetics; Pathogenesis; Treatment Outcome
Regulation of Leukemia Stem Cell Activity by Signaling through PKC[theta]
Principal investigators: Weng, Andrew P
Keywords: Cancer; Cancer Stem Cells; Chemotherapy; Leukemia; Leukemia Stem Cells; Mass Spectrometry; Mouse Models; Notch; Pkctheta; Signal Transduction
Program Overview: The Terry Fox New Frontiers Program Project in Core Pathogenic Pathways in Human Leukemia (Dr. R Keith Humphries)
Principal investigators: Humphries, R. K; Brinkman, Ryan; Eaves, Connie J; Hirst, Martin; Karsan, Aly; Weng, Andrew P
Keywords: Bioinformatics; Core Pathogenic Pathways; Disease Progression; Epigenomics And Genomics; Flow Cytometry; Genetic Engineering; Human Leukemia Models; Shared Molecular Mechanisms; Xenografts
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Christian Steidl and Ali Bashashati: 5 shared papers
- Ryan Brinkman and Andrew Weng: 2 shared papers
- Andrew Weng and Christian Steidl: 2 shared papers
- Christian Steidl and Marco Marra: 2 shared papers
- Ryan Brinkman and Ali Bashashati: 1 shared paper
- Andrew Weng and Marco Marra: 1 shared paper
- Andrew Weng and Ali Bashashati: 1 shared paper
- Andrew Weng and Lucia Nappi: 1 shared paper
- Christian Steidl and Lucia Nappi: 1 shared paper
- Terry Fox Laboratory
- Experimental Therapeutics
- Pathology and Laboratory Medicine
- Urologic Sciences
- Genome Sciences Centre
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Christian Steidl
Experimental Therapeutics
2 shared papers, latest 2024
Ryan Brinkman
Terry Fox Laboratory
2 shared papers, latest 2024
Marco Marra
Genome Sciences Centre
1 shared papers, latest 2024
Ali Bashashati
Pathology and Laboratory Medicine
1 shared papers, latest 2009
Lucia Nappi
Urologic Sciences
1 shared papers, latest 2022
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