Faculty profile

Ryan Brinkman

ResearcherTerry Fox LaboratoryUniversity of British Columbia

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.

Ryan Brinkman

Researcher

Terry Fox Laboratory

Health Sciences

University of British Columbia

Vancouver, British Columbia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
3 publications in the last five years, latest in 2026.
Principal investigator on 6 research grants (4 CIHR, 2 NSERC), most recently in 2020.
Supervised 1 trainee who won CIHR awards, most recently in 2014.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

602

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Flow Cytometry Bioinformatics Automated Analysis Big Data Biomarker Discovery Canjcer Diagnosis Immunology

Latest papers

Reproducible detection of antigen-specific T cells and Tregs via standardized and automated activation-induced marker assay workflows
Cell Reports: Methods · 2026
Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life.
Journal of immunology research · 2024
MAGIC-DR: An interpretable machine-learning guided approach for acute myeloid leukemia measurable residual disease analysis.
Cytometry. Part B, Clinical cytometry · 2024

All 16 publications

Latest funding

The Canadian Bioinformatics, Computational Biology and Health Data Sciences Training and Community Platform (BCBHDS Platform)
CIHR · 2024 · Co-investigator
$5,550,000
Automated analysis of high dimensional flow cytometry data
NSERC · 2020 · Principal investigator
$201,600
Machine Learning for Flow Cytometry Clinical Data and Trial Analysis
CIHR · 2019 · Nominated PI
$317,475

All 11 grants and awards

16 publications.

Reproducible detection of antigen-specific T cells and Tregs via standardized and automated activation-induced marker assay workflows

Halvorson T, Boucher G, Yokosawa D, Huang JQ, Garcia R, Sanderink L, Chen L, Liu L, Fajardo-Despaigne JE, Halvorson J

Cell Reports: Methods20264 citations

DOI: 10.1016/j.crmeth.2026.101458

Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life.

Montante S, Ben-Othman R, Amenyogbe N, Angelidou A, van den Biggelaar A, Cai B, Chen Y, Darboe A, Diray-Arce J, Ford R, Idoko O, Lee A, Lo M, McEnaney K, Malek M, Martino D, Masiria G, Odumade OA, Pomat W, Shannon C, Smolen K, Consortium TE, Ozonoff A, Richmond P, Tebbutt S, Levy O, Kampmann B, Brinkman R, Kollmann T

Journal of immunology research2024

DOI: 10.1155/2024/1117796 PMID: 39081632

MAGIC-DR: An interpretable machine-learning guided approach for acute myeloid leukemia measurable residual disease analysis.

Shopsowitz K, Lofroth J, Chan G, Kim J, Rana M, Brinkman R, Weng A, Medvedev N, Wang X

Cytometry. Part B, Clinical cytometry2024

DOI: 10.1002/cyto.b.22168 PMID: 38415807

Data File Standard for Flow Cytometry, Version FCS 3.2.

Spidlen J, Moore W, Parks D, Goldberg M, Blenman K, Cavenaugh JS, ISAC Data Standards Task Force, Brinkman R

Cytometry. Part A : the journal of the International Society for Analytical Cytology2021

DOI: 10.1002/cyto.a.24225 PMID: 32881398

ISAC Probe Tag Dictionary: Standardized Nomenclature for Detection and Visualization Labels Used in Cytometry and Microscopy Imaging.

Blenman KRM, Spidlen J, Parks DR, Moore W, Treister A, Leif R, Bray C, Goldberg M, ISAC Data Standards Task Force, Brinkman R

Cytometry. Part A : the journal of the International Society for Analytical Cytology2021

DOI: 10.1002/cyto.a.24224 PMID: 32881392

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML.

Lin H, Rothe K, Chen M, Wu A, Babaian A, Yen R, Zeng J, Ruschmann J, Petriv OI, O'Neill K, Maetzig T, Knapp DJHF, Nakamichi N, Brinkman R, Birol I, Forrest DL, Hansen C, Humphries RK, Eaves CJ, Jiang X

Blood2020

DOI: 10.1182/blood.2019003636 PMID: 32270193

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.

Abeler-Dörner L, Laing AG, Lorenc A, Ushakov DS, Clare S, Speak AO, Duque-Correa MA, White JK, Ramirez-Solis R, Saran N, Bull KR, Morón B, Iwasaki J, Barton PR, Caetano S, Hng KI, Cambridge E, Forman S, Crockford TL, Griffiths M, Kane L, Harcourt K, Brandt C, Notley G, Babalola KO, Warren J, Mason JC, Meeniga A, Karp NA, Melvin D, Cawthorne E, Weinrick B, Rahim A, Drissler S, Meskas J, Yue A, Lux M, Song-Zhao GX, Chan A, Ballesteros Reviriego C, Abeler J, Wilson H, Przemska-Kosicka A, Edmans M, Strevens N, Pasztorek M, Meehan TF, Powrie F, Brinkman R, Dougan G, Jacobs W, Lloyd CM, Cornall RJ, Maloy KJ, Grencis RK, Griffiths GM, Adams DJ, Hayday AC

Nature immunology2020

DOI: 10.1038/s41590-019-0549-0 PMID: 31844327

The Ontology for Biomedical Investigations.

Bandrowski A, Brinkman R, Brochhausen M, Brush MH, Bug B, Chibucos MC, Clancy K, Courtot M, Derom D, Dumontier M, Fan L, Fostel J, Fragoso G, Gibson F, Gonzalez-Beltran A, Haendel MA, He Y, Heiskanen M, Hernandez-Boussard T, Jensen M, Lin Y, Lister AL, Lord P, Malone J, Manduchi E, McGee M, Morrison N, Overton JA, Parkinson H, Peters B, Rocca-Serra P, Ruttenberg A, Sansone SA, Scheuermann RH, Schober D, Smith B, Soldatova LN, Stoeckert CJ, Taylor CF, Torniai C, Turner JA, Vita R, Whetzel PL, Zheng J

PloS one2016

DOI: 10.1371/journal.pone.0154556 PMID: 27128319

Bim regulates alloimmune-mediated vascular injury through effects on T-cell activation and death.

von Rossum A, Enns W, Shi YP, MacEwan GE, Malekesmaeli M, Brinkman R, Choy JC

Arteriosclerosis, thrombosis, and vascular biology2014

DOI: 10.1161/atvbaha.114.303649 PMID: 24700126

Computational analysis of high-dimensional flow cytometric data for diagnosis and discovery.

Aghaeepour N, Brinkman R

Current topics in microbiology and immunology2014Senior author

DOI: 10.1007/82_2013_337 PMID: 23975083

The Canadian Bioinformatics, Computational Biology and Health Data Sciences Training and Community Platform (BCBHDS Platform)

Co-investigatorCIHR2024Training Grant: HRTP - Bioinformatics, Computational Biology, Health Data Scien.

Principal investigators: Brazas, Michelle D; Bourque, Guillaume; Hsiao, William; Hughes, Nia; Hussin, Julie; Kong, Jude D; Pai, Shraddha; Sukhai, Mahadeo; Wasserman, Wyeth W; Wishart, David S

Keywords: Bioinformatics, Computational Biology & Health Data Science; Championing Diverse Talent And Careers; Competency Based Learning Pathways; Graduates, Post-Graduates And Early Career Researchers; Idea- And Career-Focused Matched Mentorship Guidance; Interdisciplinary, Intersectoral Capacity Building; Local Training Opportunities And Awards; National Community Building Activities; On-Demand, Virtual And In-Person Training; Professional Development Training

$5,550,000

Automated analysis of high dimensional flow cytometry data

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Brinkman, Ryan

$201,600

Machine Learning for Flow Cytometry Clinical Data and Trial Analysis

Nominated PICIHR2019Project Grant

Principal investigators: Brinkman, Ryan; Weng, Andrew P

Keywords: Automated Analysis; Big Data; Biomarker Discovery; Canjcer; Diagnosis; Flow Cytometry; Immunology; Immunotherapy; Machine Learning

$317,475

Standardization of Immuno-analytic Platforms for Autoimmunity Research (SIPAR)

Co-investigatorCIHR2017Team Grant: Human Immunology Initiative: Standardization Core - LOI

Principal investigators: Guidos, Cynthia J

Keywords: Autoimmune Disease; Bioinformatics; Flow Cytometry; Gene Expression Profiling; Immune Phenotyping; Mass Cytometry; Rna Sequencing

$25,000

Resolution of inter- and intra-tumoral heterogeneity in DLBCL using mass cytometry

Co-investigatorCIHR2016Project Grant

Principal investigators: Weng, Andrew P

Keywords: Biomarker; Cytof; Dlbcl; Dna Mutation; Flow Cytometry; Immune Profiling; Intratumoral Heterogeneity; Lymphoma; Mass Cytometry; Rna-Seq

$860,064

Automated analysis of big flow cytometry data.

Nominated PICIHR2016Operating Grant: Bioinformatics and Computational Biology

Principal investigators: Brinkman, Ryan

Keywords: Bioinformatics

$131,232

ICS IG 2014 Computational Biology Undergraduate Summer Student Health Research award - Understanding the molecular basis underlying differential effects of hematopoietic cytokines by derivation of networks from multi-parameter single-cell data.

SupervisorCIHR2014Undergraduate: Summer Studentship Award - Institute Community Support

Principal investigators: Wei, Lisa

Keywords: Hematopoietic Cytokines

$5,000

Automated analysis of high dimensional flow cytometry data

Principal investigatorNSERC2013Discovery Grants Program - Individual

Principal investigators: Brinkman, Ryan

$215,000

Program Overview: The Terry Fox New Frontiers Program Project in Core Pathogenic Pathways in Human Leukemia (Dr. R Keith Humphries)

Principal investigatorCIHR2012Team Grant: Terry Fox New Frontiers Program in Cancer

Principal investigators: Humphries, R. K; Brinkman, Ryan; Eaves, Connie J; Hirst, Martin; Karsan, Aly; Weng, Andrew P

Keywords: Bioinformatics; Core Pathogenic Pathways; Disease Progression; Epigenomics And Genomics; Flow Cytometry; Genetic Engineering; Human Leukemia Models; Shared Molecular Mechanisms; Xenografts

CIHR Training Grant in Bioinformatics for Health Research

Co-investigatorCIHR2008Training Grant

Principal investigators: Jones, Steven; Brinkman, Fiona S

Keywords: Bioinformatics; Computer Science; Epidemiology; Genomics; Proteomics; Statistics

$1,950,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Ryan Brinkman

Research

Latest papers

Latest funding

Reproducible detection of antigen-specific T cells and Tregs via standardized and automated activation-induced marker assay workflows

Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life.

MAGIC-DR: An interpretable machine-learning guided approach for acute myeloid leukemia measurable residual disease analysis.

Data File Standard for Flow Cytometry, Version FCS 3.2.

ISAC Probe Tag Dictionary: Standardized Nomenclature for Detection and Visualization Labels Used in Cytometry and Microscopy Imaging.

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML.

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.

The Ontology for Biomedical Investigations.

Bim regulates alloimmune-mediated vascular injury through effects on T-cell activation and death.

Computational analysis of high-dimensional flow cytometric data for diagnosis and discovery.

The Canadian Bioinformatics, Computational Biology and Health Data Sciences Training and Community Platform (BCBHDS Platform)

Automated analysis of high dimensional flow cytometry data

Machine Learning for Flow Cytometry Clinical Data and Trial Analysis

Standardization of Immuno-analytic Platforms for Autoimmunity Research (SIPAR)

Resolution of inter- and intra-tumoral heterogeneity in DLBCL using mass cytometry

Automated analysis of big flow cytometry data.

ICS IG 2014 Computational Biology Undergraduate Summer Student Health Research award - Understanding the molecular basis underlying differential effects of hematopoietic cytokines by derivation of networks from multi-parameter single-cell data.

Automated analysis of high dimensional flow cytometry data

Program Overview: The Terry Fox New Frontiers Program Project in Core Pathogenic Pathways in Human Leukemia (Dr. R Keith Humphries)

CIHR Training Grant in Bioinformatics for Health Research

Frequent collaborators

Andrew Weng

Jonathan Bramson

Tobias Kollmann

Xiaoyan Jiang

Inanc Birol

Suzanne Vercauteren

Scott Tebbutt

Ali Bashashati

Amy Lee

Connie Eaves

Nelly Amenyogbe