This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing.
Cell · 2019
A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data.
Blood · 2019
Single-cell analysis identifies a CD33+ subset of human cord blood cells with high regenerative potential.
Nature cell biology · 2018
Latest funding
- $2,833,460
Targeting the dynamics and genomics of clonal evolution in cancer patients
CIHR · 2015 · Co-investigator
- $442,500
Microfluidic technology platform for selection of functional monoclonal antibodies with application to fibrosis
NSERC · 2015 · Principal investigator
- $2,121,669
Lipid nanomedicines for health and disease
CIHR · 2015 · Co-investigator
8 publications.
Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing.
Laks E, McPherson A, Zahn H, Lai D, Steif A, Brimhall J, Biele J, Wang B, Masud T, Ting J, Grewal D, Nielsen C, Leung S, Bojilova V, Smith M, Golovko O, Poon S, Eirew P, Kabeer F, Ruiz de Algara T, Lee SR, Taghiyar MJ, Huebner C, Ngo J, Chan T, Vatrt-Watts S, Walters P, Abrar N, Chan S, Wiens M, Martin L, Scott RW, Underhill TM, Chavez E, Steidl C, Da Costa D, Ma Y, Coope RJN, Corbett R, Pleasance S, Moore R, Mungall AJ, Mar C, Cafferty F, Gelmon K, Chia S, CRUK IMAXT Grand Challenge Team, Marra MA, Hansen C, Shah SP, Aparicio S
A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data.
Knapp DJHF, Hammond CA, Wang F, Aghaeepour N, Miller PH, Beer PA, Pellacani D, VanInsberghe M, Hansen C, Bendall SC, Nolan GP, Eaves CJ
Single-cell analysis identifies a CD33+ subset of human cord blood cells with high regenerative potential.
Knapp DJHF, Hammond CA, Hui T, van Loenhout MTJ, Wang F, Aghaeepour N, Miller PH, Moksa M, Rabu GM, Beer PA, Pellacani D, Humphries RK, Hansen C, Hirst M, Eaves CJ
Distinct signaling programs control human hematopoietic stem cell survival and proliferation.
Knapp DJ, Hammond CA, Aghaeepour N, Miller PH, Pellacani D, Beer PA, Sachs K, Qiao W, Wang W, Humphries RK, Sauvageau G, Zandstra PW, Bendall SC, Nolan GP, Hansen C, Eaves CJ
Dissociation of Survival, Proliferation, and State Control in Human Hematopoietic Stem Cells.
Knapp DJ, Hammond CA, Miller PH, Rabu GM, Beer PA, Ricicova M, Lecault V, Da Costa D, VanInsberghe M, Cheung AM, Pellacani D, Piret J, Hansen C, Eaves CJ
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.
Eirew P, Steif A, Khattra J, Ha G, Yap D, Farahani H, Gelmon K, Chia S, Mar C, Wan A, Laks E, Biele J, Shumansky K, Rosner J, McPherson A, Nielsen C, Roth AJ, Lefebvre C, Bashashati A, de Souza C, Siu C, Aniba R, Brimhall J, Oloumi A, Osako T, Bruna A, Sandoval JL, Algara T, Greenwood W, Leung K, Cheng H, Xue H, Wang Y, Lin D, Mungall AJ, Moore R, Zhao Y, Lorette J, Nguyen L, Huntsman D, Eaves CJ, Hansen C, Marra MA, Caldas C, Shah SP, Aparicio S
Unidirectional P-body transport during the yeast cell cycle.
Garmendia-Torres C, Skupin A, Michael SA, Ruusuvuori P, Kuwada NJ, Falconnet D, Cary GA, Hansen C, Wiggins PA, Dudley AM
Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfluidic mixing.
Zhigaltsev IV, Belliveau N, Hafez I, Leung AK, Huft J, Hansen C, Cullis PR
Targeting the dynamics and genomics of clonal evolution in cancer patients
Principal investigators: Aparicio, Samuel J
Keywords: Breast Cancer; Cancer; Clonal Evolution; Clonal Genomes; Genomics; Oncology; Patient-Derived Xenografts; Single Cell; Therapeutics; Translational Medicine
Microfluidic technology platform for selection of functional monoclonal antibodies with application to fibrosis
Principal investigators: Hansen, Carl
Lipid nanomedicines for health and disease
Principal investigators: Cullis, Pieter R
Keywords: Anticancer; Drug Delivery System; Gene Therapy; Immunosuppressant; Lipid Nanoparticles; Mrna; Nanomedicine; Sirna; Small Molecule Drugs; Trigger Release
The clonal dynamics of ovarian cancers: phylogenetic models of chemosensitivity and resistance
Principal investigators: Shah, Sohrab P
Keywords: Clonal Dynamics; Computational Biology; Dna Repair; Genomic Instability; Genomic Signatures; Homologous Recombination; Next-Generation Sequencing; Ovarian Cancer; Response Prediction; Tumour Evolution
Commercialization of a new technology for therapeutic antibody discovery - I2I phase IIb
Principal investigators: Hansen, Carl
A high-throughput single-cell technology for the function-based discovery of monoclonal antibody antagonists of G-protein coupled receptors in cancer
Principal investigators: Hansen, Carl L
Keywords: Antibody Selection; Antibody Therapeutics; G-Protein Coupled Receptors; Immunogenomics; Microfluidics; Receptor Antagonists; Single Cell Analysis
Microfluidic technology platform for selection of functional monoclonal antibodies with application to fibrosis
Principal investigators: Hansen, Carl L; Rossi, Fabio M; Underhill, Michael
Keywords: Fibrosis; Microfluidics; Neutralizing Antibodies; Signalling Receptors; Single Cell Analysis
Pre-commercial development of single cell antibody selection process
Principal investigators: Hansen, Carl L
Keywords: Antibody Screening; Biologics; Biophysics; Clone Selection; Human Monoclonal Antibodies; Immunology; Microfluidics; Single Cell; Therapeutics
The development of single cell microfluidic technologies for analysis of microRNA expression and epigenetic state with application to hematopoietic stem cells
Principal investigators: Hansen, Carl
A scale-up microfluidic-based manufacturing process for the production of therapeutic lipid nanoparticles: a I2I phase 2b project
Principal investigators: Cullis, Pieter
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Martin Hirst and Samuel Aparicio: 14 shared papers
- Samuel Aparicio and Ali Bashashati: 12 shared papers
- David Huntsman and Samuel Aparicio: 7 shared papers
- David Huntsman and Ali Bashashati: 6 shared papers
- Samuel Aparicio and Adi Steif: 6 shared papers
- Martin Hirst and Christian Steidl: 5 shared papers
- Martin Hirst and Ali Bashashati: 5 shared papers
- Christian Steidl and Samuel Aparicio: 5 shared papers
- Christian Steidl and Ali Bashashati: 5 shared papers
- Martin Hirst and David Huntsman: 4 shared papers
- Yuzhuo Wang and David Huntsman: 2 shared papers
- Carl Hansen and Samuel Aparicio: 2 shared papers
- Carl Hansen and Adi Steif: 2 shared papers
- Ali Bashashati and Adi Steif: 2 shared papers
- Martin Hirst and Yuzhuo Wang: 1 shared paper
- Martin Hirst and Carl Hansen: 1 shared paper
- Yuzhuo Wang and Carl Hansen: 1 shared paper
- David Huntsman and Carl Hansen: 1 shared paper
- Christian Steidl and Carl Hansen: 1 shared paper
- Carl Hansen and Guy Sauvageau: 1 shared paper
- Carl Hansen and James Piret: 1 shared paper
- Carl Hansen and Ali Bashashati: 1 shared paper
- Samuel Aparicio and James Piret: 1 shared paper
- Molecular Oncology
- Genome Sciences Centre
- Pathology and Laboratory Medicine
- Experimental Therapeutics
- Institut de recherche en immunologie et cancer
- Michael Smith Laboratories
- Microbiology and Immunology
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Samuel Aparicio
Molecular Oncology
2 shared papers, latest 2019
Adi Steif
Genome Sciences Centre
2 shared papers, latest 2019
Guy Sauvageau
Institut de recherche en immunologie et cancer
1 shared papers, latest 2017
James Piret
Michael Smith Laboratories
1 shared papers, latest 2017
Ali Bashashati
Pathology and Laboratory Medicine
1 shared papers, latest 2015
Martin Hirst
Microbiology and Immunology
1 shared papers, latest 2018
Yuzhuo Wang
Urologic Sciences
1 shared papers, latest 2015
David Huntsman
Molecular Oncology
1 shared papers, latest 2015
Christian Steidl
Experimental Therapeutics
1 shared papers, latest 2019
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