Faculty profile
Decheng Yang
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Cyclodextrin Counteracts Coxsackievirus-Induced Cardiac Damage by Protecting Desmosome Integrity and Suppressing Proinflammatory Cytokine Expression.
Microorganisms · 2025 · senior author
Heart-specific NFAT5 knockout suppresses type I interferon signaling and aggravates coxsackievirus-induced myocarditis.
Basic research in cardiology · 2024 · senior author
Coxsackievirus B3-Induced m6A Modification of RNA Enhances Viral Replication via Suppression of YTHDF-Mediated Stress Granule Formation.
Microorganisms · 2024 · senior author
Latest funding
- $604,350
Role of transcription factor NFAT5 in viral myocarditis: a novel strategy for therapy
CIHR · 2019 · Nominated PI
- $204,000
Mechanisms of selective host gene translation regulation in picornavirus infection
NSERC · 2017 · Principal investigator
- $500,232
IRES-dependent translation of heat shock proteins in the pathogenesis of coxsackievirus myocarditis
CIHR · 2012 · Nominated PI
48 publications.
Cyclodextrin Counteracts Coxsackievirus-Induced Cardiac Damage by Protecting Desmosome Integrity and Suppressing Proinflammatory Cytokine Expression.
Zhao G, Zhang HM, Zhang GJ, Yang W, Küper C, McManus BM, Yang D
Heart-specific NFAT5 knockout suppresses type I interferon signaling and aggravates coxsackievirus-induced myocarditis.
Zhao G, Zhang HM, Nasseri AR, Yip F, Telkar N, Chen YT, Aghakeshmiri S, Küper C, Lam W, Yang W, Zhao J, Luo H, McManus BM, Yang D
Coxsackievirus B3-Induced m6A Modification of RNA Enhances Viral Replication via Suppression of YTHDF-Mediated Stress Granule Formation.
Zhao G, Zhang HM, Chen YT, Shi K, Aghakeshmiri S, Yip F, Luo H, McManus B, Yang D
m6A reader proteins: the executive factors in modulating viral replication and host immune response.
Yang D, Zhao G, Zhang HM
Role of Coxsackievirus B3-Induced Immune Responses in the Transition from Myocarditis to Dilated Cardiomyopathy and Heart Failure.
Yip F, Lai B, Yang D
Zika Virus Infection Downregulates Connexin 43, Disrupts the Cardiomyocyte Gap Junctions and Induces Heart Diseases in A129 Mice.
Li S, Armstrong N, Zhao H, Cruz-Cosme R, Yang H, Zhong C, Fu W, Wang W, Yang D, Xia N, Cheng T, Tang Q
Poly(rC) binding protein 1 benefits coxsackievirus B3 infection via suppressing the translation of p62/SQSTM1.
He HY, You Z, Ouyang T, Zhao G, Chen LJ, Wang Q, Li JY, Ye X, Zhang MH, Yang D, Ge XY, Qiu Y
NFAT5-Mediated Signalling Pathways in Viral Infection and Cardiovascular Dysfunction.
Zhao G, Aghakeshmiri S, Chen YT, Zhang HM, Yip F, Yang D
Cleavage and degradation of EDEM1 promotes coxsackievirus B3 replication via ATF6a-mediated unfolded protein response signalling.
Zhang HM, Qiu Y, Zhao G, Wang H, Chen YT, Aghakeshmiri S, Hanson P, Yang D
Cleavage of Desmosomal Cadherins Promotes γ-Catenin Degradation and Benefits Wnt Signaling in Coxsackievirus B3-Induced Destruction of Cardiomyocytes.
Zhao G, Zhang HM, Qiu Y, Ye X, Yang D
Role of transcription factor NFAT5 in viral myocarditis: a novel strategy for therapy
Principal investigators: Yang, Decheng
Keywords: Antiviral Therapy; Conditional Knockout Mouse; Crispr/Cas9; Inducible Nitric Oxide Synthase (Inos); Nfat5 Transcription Factor; Nfkb; Viral Myocarditis; Viral Pathogenesis; Viral Protease
Mechanisms of selective host gene translation regulation in picornavirus infection
Principal investigators: Yang, Decheng
IRES-dependent translation of heat shock proteins in the pathogenesis of coxsackievirus myocarditis
Principal investigators: Yang, Decheng
Keywords: Cellular Chaperone; Coxsackieviral Pathogenesis; Heat Shock Protein 70; Internal Ribosome Entry Site (Ires) - Dependent Translation; Viral Myocarditis
MicroRNA-mediated gene regulation as a determinant of tissue tropism and pathogenesis in coxsackievirus infection
Principal investigators: Yang, Decheng
Keywords: Heart Disease; Heart Muscle Cell Injury; Organ Specific Infection; Virus Infection
High-throughput screening and identification of anti-viral myocarditis compounds from a marine microbial natural product library
Principal investigators: Yang, Decheng; Dai, Huanqin
Keywords: Antiviral; Coxsackievirus; Drug Development; High-Throughput Screening; Natural Product Medicine; Viral Myocarditis
CIHR IMPACT Strategic Training Program
Principal investigators: Walley, Keith R
Keywords: Cardiovascular; Cell And Molecular Biology; Clinical Research; Clinician-Scientist; Environment; Gene; Genotyping; Imaging; Mentoring; Phenotyping; Physiology; Pulmonary; Teaching; Training; Transdisciplinary Thematic Research
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Pathology and Laboratory Medicine
- Computer Science
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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