Faculty profile
Bruce McManus
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Coxsackievirus B3-Induced m6A Modification of RNA Enhances Viral Replication via Suppression of YTHDF-Mediated Stress Granule Formation.
Microorganisms · 2024
Cardiometabolic Co-morbidity Burden and Circulating Biomarkers in Patients With Chronic Coronary Disease in the ISCHEMIA Trials.
The American journal of cardiology · 2024
Biomarkers and cardiovascular events in patients with stable coronary disease in the ISCHEMIA Trials.
American heart journal · 2023
Latest funding
- $604,350
Role of transcription factor NFAT5 in viral myocarditis: a novel strategy for therapy
CIHR · 2019 · Co-investigator
- $2,180,250
HEARTBiT: A novel multi-marker blood test for management of acute cardiac allograft rejection
CIHR · 2017 · Nominated PI
- $100,000
A novel multi-marker blood test for management of acute cardiac allograft rejection
CIHR · 2016 · Nominated PI
40 publications.
Coxsackievirus B3-Induced m6A Modification of RNA Enhances Viral Replication via Suppression of YTHDF-Mediated Stress Granule Formation.
Zhao G, Zhang HM, Chen YT, Shi K, Aghakeshmiri S, Yip F, Luo H, McManus B, Yang D
Cardiometabolic Co-morbidity Burden and Circulating Biomarkers in Patients With Chronic Coronary Disease in the ISCHEMIA Trials.
Hamo CE, Liu R, Wu W, Anthopolos R, Bangalore S, Held C, Kullo I, Mavromatis K, McManus B, Newby LK, Reynolds HR, Ruggles KV, Wallentin L, Maron DJ, Hochman JS, Newman JD, Berger JS, ISCHEMIA Biorepository Research Group
Biomarkers and cardiovascular events in patients with stable coronary disease in the ISCHEMIA Trials.
Newman JD, Anthopolos R, Ruggles KV, Cornwell M, Reynolds HR, Bangalore S, Mavromatis K, Held C, Wallentin L, Kullo IJ, McManus B, Newby LKK, Rosenberg Y, Hochman JS, Maron DJ, Berger JS, ISCHEMIA Biorepository Research Group
The Covid-19 Pandemic Has Exposed Opportunities To Strengthen Our Health Research Systems.
Holmes BJ, MacKenzie A, McManus B, Angel AA
Long-chain fatty acids are bad in IPF, or are they?
McManus B, Knight D
Epidemiological Impact of Myocarditis.
Golpour A, Patriki D, Hanson PJ, McManus B, Heidecker B
Virome Sequencing in Patients With Myocarditis.
Heidecker B, Williams SH, Jain K, Oleynik A, Patriki D, Kottwitz J, Berg J, Garcia JA, Baltensperger N, Lovrinovic M, Baltensweiler A, Mishra N, Briese T, Hanson PJ, Lauten A, Poller W, Leistner DM, Landmesser U, Enseleit F, McManus B, Lüscher TF, Lipkin WI
Bioprosthetic Valve Leaflet Displacement During Valve-in-Valve Intervention: An Ex Vivo Bench Study.
Hensey M, Sellers S, Sathananthan J, Lai A, Landes U, Alkhodair A, McManus B, Cheung A, Wood D, Blanke P, Leipsic J, Ye J, Webb J
The design and rationale of SAVE BC: The Study to Avoid CardioVascular Events in British Columbia.
Brunham LR, Lynch K, English A, Sutherland R, Weng J, Cho R, Wong GC, Anis AH, Francis GA, Khan NA, McManus B, Wood D, Walley KR, Leipsic J, Humphries KH, Hoens A, Krahn AD, John Mancini GB, Pimstone S
The Super-Seniors Study: Phenotypic characterization of a healthy 85+ population.
Halaschek-Wiener J, Tindale LC, Collins JA, Leach S, McManus B, Madden K, Meneilly G, Le ND, Connors JM, Brooks-Wilson AR
Role of transcription factor NFAT5 in viral myocarditis: a novel strategy for therapy
Principal investigators: Yang, Decheng
Keywords: Antiviral Therapy; Conditional Knockout Mouse; Crispr/Cas9; Inducible Nitric Oxide Synthase (Inos); Nfat5 Transcription Factor; Nfkb; Viral Myocarditis; Viral Pathogenesis; Viral Protease
HEARTBiT: A novel multi-marker blood test for management of acute cardiac allograft rejection
Principal investigators: McManus, Bruce M; Ng, Raymond; Tebbutt, Scott J
Keywords: Acute Immune Rejection; Bioinformatics; Biomarkers; Clinical Testing; Computational Biology; Diagnostics; Heart Transplantation; Multi-Omics Integration; Observational Cohort Study; Omics
A novel multi-marker blood test for management of acute cardiac allograft rejection
Principal investigators: McManus, Bruce M; Ng, Raymond; Tebbutt, Scott J
Keywords: Acute Rejection; Bioinformatics; Biomarkers; Clinical Tests; Computational Biology; Diagnostics; Heart Transplant; Observational Cohort Study; Omics
Using Multi-Omics To Discover Novel Biomarkers and Therapeutic Targets for Chronic Obstructive Pulmonary Disease
Principal investigators: Sin, Donald
Keywords: Biomarker; Copd; Genomics; Proteomics; Systems Biology
Granzymes in Tissue Injury, Inflammation and Repair
Principal investigators: Granville, David J
Keywords: Aging; Cardiovascular; Connective Tissue Disease; Dermatology; Extracellular Matrix; Inflammation; Proteases; Tissue Injury; Tissue Repair; Wound Healing
Heart and Lung Health FEST 2012
Principal investigators: McManus, Bruce M
Keywords: Education; Health; Heart; Lung; Science
Genome-wide Association Study of Aortic Valve Stenosis
Principal investigators: Brooks-Wilson, Angela R; McManus, Bruce M
Keywords: Aortic Valve Stenosis; Cardiovascular Disease; Dna Pooling; Genetic Susceptibility; Genome-Wide Association Study; Single Nucleotide Polymorphism
Novel Targeted Strategies for Biomarker Discovery and Development
Principal investigators: Hollander, Zsuzsanna
Keywords: Bioinformatics; Biomarker Discovery; Biomarker Validation; Cardiac Transplantation; Genomics; Health Economics; Heart Failure; Proteomics; Statistics
Immunologic Functions of Acute Cardiac Allograft Rejection Biomarkers in Peripheral Blood Cells
Principal investigators: Lin, David
Keywords: Biomarker; Cardiac Allograft Rejection; Cardiovascular Disease; Cardiovascular Pathology; Flow Cytometry; Immunophenotyping; Molecular Biology; Real-Time Polymerase Chain Reaction; Transplantation Immunology
Fibrosis: cellular origins and therapeutic strategies
Principal investigators: Rossi, Fabio M; Kast, Juergen; Knight, Darryl A; McManus, Bruce M; McNagny, Kelly M; Underhill, Michael; Vallance, Bruce A; Zaph, Colby
Keywords: Chronic Inflammation; Fibrosis (Multiple Diseases); Genetic Disease; Regenerative Medicine
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Ma'en Obeidat and Philippe Joubert: 13 shared papers
- Stephen Lam and Ma'en Obeidat: 8 shared papers
- Wan Lam and Stephen Lam: 6 shared papers
- Decheng Yang and Bruce McManus: 6 shared papers
- Honglin Luo and Bruce McManus: 5 shared papers
- Honglin Luo and Decheng Yang: 4 shared papers
- Honglin Luo and Mitra Esfandiarei: 4 shared papers
- Jonathon Leipsic and Stephen Lam: 4 shared papers
- Bruce McManus and Ma'en Obeidat: 4 shared papers
- Cheryl Wellington and Veronica Hirsch Reinshagen: 3 shared papers
- Tillie-Louise Hackett and Ma'en Obeidat: 3 shared papers
- Stephen Lam and Philippe Joubert: 3 shared papers
- Bruce McManus and Raymond Ng: 3 shared papers
- Raymond Ng and Scott Tebbutt: 3 shared papers
- Wan Lam and Ma'en Obeidat: 2 shared papers
- Mohsen Sadatsafavi and Raymond Ng: 2 shared papers
- Mohsen Sadatsafavi and Ma'en Obeidat: 2 shared papers
- Jonathon Leipsic and Bruce McManus: 2 shared papers
- Bruce McManus and Paul Keown: 2 shared papers
- Bruce McManus and Mitra Esfandiarei: 2 shared papers
- Cheryl Wellington and Bruce McManus: 1 shared paper
- Wan Lam and Honglin Luo: 1 shared paper
- Wan Lam and Decheng Yang: 1 shared paper
- Wan Lam and Tillie-Louise Hackett: 1 shared paper
- Wan Lam and Jonathon Leipsic: 1 shared paper
- Wan Lam and Bruce McManus: 1 shared paper
- Wan Lam and Philippe Joubert: 1 shared paper
- Honglin Luo and Tillie-Louise Hackett: 1 shared paper
- Mohsen Sadatsafavi and Stephen Lam: 1 shared paper
- Mohsen Sadatsafavi and Bruce McManus: 1 shared paper
- Mohsen Sadatsafavi and Kenneth Madden: 1 shared paper
- Tillie-Louise Hackett and Bruce McManus: 1 shared paper
- Tillie-Louise Hackett and Samuel Wadsworth: 1 shared paper
- Fabio Rossi and Bruce McManus: 1 shared paper
- Jonathon Leipsic and Simon Pimstone: 1 shared paper
- Stephen Lam and Bruce McManus: 1 shared paper
- Bruce McManus and Scott Tebbutt: 1 shared paper
- Bruce McManus and Samuel Wadsworth: 1 shared paper
- Bruce McManus and Simon Pimstone: 1 shared paper
- Bruce McManus and Kenneth Madden: 1 shared paper
- Bruce McManus and Veronica Hirsch Reinshagen: 1 shared paper
- Bruce McManus and Philippe Joubert: 1 shared paper
- Raymond Ng and Paul Keown: 1 shared paper
- Scott Tebbutt and Paul Keown: 1 shared paper
- Pathology and Laboratory Medicine
- Medicine
- Anesthesiology, Pharmacology and Therapeutics
- Computer Science
- Biomedical Engineering
- Physical Therapy
- Medicine/Respirology
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Decheng Yang
Pathology and Laboratory Medicine
6 shared papers, latest 2024
Honglin Luo
Pathology and Laboratory Medicine
5 shared papers, latest 2024
Ma'en Obeidat
Medicine
4 shared papers, latest 2017
Raymond Ng
Computer Science
3 shared papers, latest 2017
Mitra Esfandiarei
Anesthesiology, Pharmacology and Therapeutics
2 shared papers, latest 2007
Paul Keown
Faculty
2 shared papers, latest 2017
Jonathon Leipsic
Faculty
2 shared papers, latest 2020
Philippe Joubert
Faculty
1 shared papers, latest 2017
Scott Tebbutt
Medicine
1 shared papers, latest 2017
Simon Pimstone
Medicine
1 shared papers, latest 2018
Kenneth Madden
Physical Therapy
1 shared papers, latest 2018
Veronica Hirsch Reinshagen
Faculty
1 shared papers, latest 2008
Samuel Wadsworth
Anesthesiology, Pharmacology and Therapeutics
1 shared papers, latest 2011
Tillie-Louise Hackett
Anesthesiology, Pharmacology and Therapeutics
1 shared papers, latest 2017
Fabio Rossi
Biomedical Engineering
1 shared papers, latest 2013
Cheryl Wellington
Pathology and Laboratory Medicine
1 shared papers, latest 2008
Stephen Lam
Faculty
1 shared papers, latest 2017
Wan Lam
Faculty
1 shared papers, latest 2017
Mohsen Sadatsafavi
Medicine/Respirology
1 shared papers, latest 2015
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