Ujendra Kumar, University of British Columbia

Research

Read how they describe their research on their University of British Columbia profile.

Latest papers

Somatostatinergic and dopaminergic systems in Alzheimer's disease: Mechanistic insights and therapeutic opportunities beyond plaques and tangles.
Neural regeneration research · 2026 · senior author
Brain region-specific dopamine receptor changes and astrocyte activation influence tau pathology through CDK5 in Alzheimer's disease models.
Journal of Alzheimer's disease : JAD · 2025 · senior author
G-Protein-Coupled Receptor-Microtubule Interactions Regulate Neurite Development and Protect Against β-Amyloid Neurotoxicity.
Molecular neurobiology · 2025 · senior author

All 64 publications

Latest funding

Development and evaluation of novel nanoparticle formulations for therapeutic genome editing
CIHR · 2023 · Co-investigator
$975,376
Development and evaluation of novel nanoparticle formulations for therapeutic genome editing
CIHR · 2022 · Co-investigator
$100,000
Pharmacological characterization of phyto-cannabinoids and endocannabinoid system
NSERC · 2021 · Principal investigator
$190,745

All 7 grants and awards

64 publications.

01

Somatostatinergic and dopaminergic systems in Alzheimer's disease: Mechanistic insights and therapeutic opportunities beyond plaques and tangles.

Singh S, Kumar U

Neural regeneration research2026Senior author

DOI: 10.4103/nrr.nrr-d-25-01038 PMID: 41975625

02

Brain region-specific dopamine receptor changes and astrocyte activation influence tau pathology through CDK5 in Alzheimer's disease models.

Singh S, Kumar U

Journal of Alzheimer's disease : JAD2025Senior author

DOI: 10.1177/13872877251389961 PMID: 41160462

03

G-Protein-Coupled Receptor-Microtubule Interactions Regulate Neurite Development and Protect Against β-Amyloid Neurotoxicity.

Singh S, Kumar U

Molecular neurobiology2025Senior author

DOI: 10.1007/s12035-025-05179-8 PMID: 40601218

04

Cannabinoids: Role in Neurological Diseases and Psychiatric Disorders.

Kumar U

International journal of molecular sciences2024First author

DOI: 10.3390/ijms26010152 PMID: 39796008

05

Somatostatin and Somatostatin Receptors in Tumour Biology.

Kumar U

International journal of molecular sciences2023First author

DOI: 10.3390/ijms25010436 PMID: 38203605

06

Comparative changes in breast cancer cell proliferation and signalling following somatostatin and cannabidiol treatment.

Oliveira HA, Somvanshi RK, Kumar U

Biochemical and biophysical research communications2023Senior author

DOI: 10.1016/j.bbrc.2022.12.073 PMID: 36586156

07

Cannabinol modulates neuroprotection and intraocular pressure: A potential multi-target therapeutic intervention for glaucoma.

Somvanshi RK, Zou S, Kadhim S, Padania S, Hsu E, Kumar U

Biochimica et biophysica acta. Molecular basis of disease2022Senior author

DOI: 10.1016/j.bbadis.2021.166325 PMID: 34921975

08

Somatostatin-Mediated Regulation of Retinoic Acid-Induced Differentiation of SH-SY5Y Cells: Neurotransmitters Phenotype Characterization.

Singh S, Somvanshi RK, Kumar U

Biomedicines2022Senior author

DOI: 10.3390/biomedicines10020337 PMID: 35203546

09

Somatostatin Ameliorates β-Amyloid-Induced Cytotoxicity via the Regulation of CRMP2 Phosphorylation and Calcium Homeostasis in SH-SY5Y Cells.

Paik S, Somvanshi RK, Oliveira HA, Zou S, Kumar U

Biomedicines2021Senior author

DOI: 10.3390/biomedicines9010027 PMID: 33401710

10

Comparative distribution of somatostatin and somatostatin receptors in PTU-induced hypothyroidism.

Singh S, Somvanshi RK, Panda V, Kumar U

Endocrine2020Senior author

DOI: 10.1007/s12020-020-02309-1 PMID: 32335798

Development and evaluation of novel nanoparticle formulations for therapeutic genome editing

Co-investigatorCIHR2023Project Grant

Principal investigators: Ross, Colin J; Blakney, Anna

Keywords: Animal Models; Base Editor; Gene Editing; Genetic Disease; Lipid Nanoparticle; Nanoparticle; Prime Editor

$975,376

Development and evaluation of novel nanoparticle formulations for therapeutic genome editing

Co-investigatorCIHR2022Project Grant

Principal investigators: Ross, Colin J; Blakney, Anna

Keywords: Animal Models; Base Editor; Gene Editing; Genetic Disease; Lipid Nanoparticle; Nanoparticle; Prime Editor

$100,000

Pharmacological characterization of phyto-cannabinoids and endocannabinoid system

Principal investigatorNSERC2021Alliance Grants

Principal investigators: Kumar, Ujendra U

Keywords: apoptosis and proliferation; cannabinoid receptors; endocannabinoid system; metabolomics; pb-fret; pharmacology; phyto-cannabinoids; protein-protein interaction; proteomics; signaling

$190,745

Neurobiology of Somatostatin Receptors: Functional Characterization in Central Nervous System

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Kumar, Ujendra

$26,000

Identification of the role of somatostatin receptor in Alzheimer's disease and excitoxicity

SupervisorCIHR2013Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Paik, Seungil

Keywords: Alzheimer'S Disease; Neurodegeneration; Somatostatin

$105,000

Modulation of synaptic transmission by GABA and metabotropic glutamate receptors

Principal investigatorNSERC2011Discovery Grants Program - Group

Principal investigators: Kumar, Ujendra

$135,000

Structure-Function and regulation of somatostatin receptors

Nominated PICIHR2009Operating Grant

Principal investigators: Kumar, Ujendra

Keywords: Alzheimer'S Disease; Neurotoxicity; Pharmacology

$295,623

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Pharmsci
Pathology and Laboratory Medicine

Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Honglin Luo

Pathology and Laboratory Medicine

1 shared papers, latest 2014

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2021

Subject: Prospective PhD student Dear Professor Kumar, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Somatostatinergic and dopaminergic systems in Alzheimer's disease: Mechanistic insights and therapeutic opportunities beyond plaques and tangles." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Pharmacological characterization of phyto-cannabinoids and endocannabinoid system" (2021), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Ujendra Kumar

Research

Latest papers

Latest funding

Somatostatinergic and dopaminergic systems in Alzheimer's disease: Mechanistic insights and therapeutic opportunities beyond plaques and tangles.

Brain region-specific dopamine receptor changes and astrocyte activation influence tau pathology through CDK5 in Alzheimer's disease models.

G-Protein-Coupled Receptor-Microtubule Interactions Regulate Neurite Development and Protect Against &#x3b2;-Amyloid Neurotoxicity.

Cannabinoids: Role in Neurological Diseases and Psychiatric Disorders.

Somatostatin and Somatostatin Receptors in Tumour Biology.

Comparative changes in breast cancer cell proliferation and signalling following somatostatin and cannabidiol treatment.

Cannabinol modulates neuroprotection and intraocular pressure: A potential multi-target therapeutic intervention for glaucoma.

Somatostatin-Mediated Regulation of Retinoic Acid-Induced Differentiation of SH-SY5Y Cells: Neurotransmitters Phenotype Characterization.

Somatostatin Ameliorates &#x3b2;-Amyloid-Induced Cytotoxicity via the Regulation of CRMP2 Phosphorylation and Calcium Homeostasis in SH-SY5Y Cells.

Comparative distribution of somatostatin and somatostatin receptors in PTU-induced hypothyroidism.

Development and evaluation of novel nanoparticle formulations for therapeutic genome editing

Development and evaluation of novel nanoparticle formulations for therapeutic genome editing

Pharmacological characterization of phyto-cannabinoids and endocannabinoid system

Neurobiology of Somatostatin Receptors: Functional Characterization in Central Nervous System

Identification of the role of somatostatin receptor in Alzheimer's disease and excitoxicity

Modulation of synaptic transmission by GABA and metabotropic glutamate receptors

Structure-Function and regulation of somatostatin receptors

Frequent collaborators

Brian Rodrigues

Honglin Luo

G-Protein-Coupled Receptor-Microtubule Interactions Regulate Neurite Development and Protect Against β-Amyloid Neurotoxicity.

Somatostatin Ameliorates β-Amyloid-Induced Cytotoxicity via the Regulation of CRMP2 Phosphorylation and Calcium Homeostasis in SH-SY5Y Cells.