Faculty profile
Brian Rodrigues
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Global knockout of VEGFB improves lipoprotein lipase activity leading to an improved lipid profile during diabetes.
Frontiers in pharmacology · 2026 · senior author
Cardioprotective effects of a 'twincretin' drug tirzepatide in heart failure following myocardial infarction.
Cardiovascular research · 2025 · senior author
Heparanase Stimulation of Physiologic Cardiac Hypertrophy Is Suppressed After Chronic Diabetes, Resulting in Cardiac Remodeling and Dysfunction.
Diabetes · 2024 · senior author
Latest funding
- $975,376
Development and evaluation of novel nanoparticle formulations for therapeutic genome editing
CIHR · 2023 · Co-investigator
- $100,000
Development and evaluation of novel nanoparticle formulations for therapeutic genome editing
CIHR · 2022 · Co-investigator
- $696,150
Role of cardiac lipoprotein lipase in diabetic heart disease.
CIHR · 2021 · Nominated PI
67 publications.
Global knockout of VEGFB improves lipoprotein lipase activity leading to an improved lipid profile during diabetes.
Wang H, Shang R, Lee CS, Hussein B, Rodrigues B
Cardioprotective effects of a 'twincretin' drug tirzepatide in heart failure following myocardial infarction.
Shang R, Rodrigues B
Heparanase Stimulation of Physiologic Cardiac Hypertrophy Is Suppressed After Chronic Diabetes, Resulting in Cardiac Remodeling and Dysfunction.
Lee CS, Shang R, Wang F, Khayambashi P, Wang H, Araujo G, Puri K, Vlodavsky I, Hussein B, Rodrigues B
Lipoprotein lipase as a target for obesity/diabetes related cardiovascular disease.
Shang R, Rodrigues B
Downregulation of adipose LPL by PAR2 contributes to the development of hypertriglyceridemia.
Huang Y, Chen L, Li L, Qi Y, Tong H, Wu H, Xu J, Leng L, Cheema S, Sun G, Xia Z, McGuire J, Rodrigues B, Young LH, Bucala R, Qi D
Reduction in Insulin Uncovers a Novel Effect of VEGFB on Cardiac Substrate Utilization.
Shang R, Lee CS, Wang H, Dyer R, Noll C, Carpentier A, Sultan I, Alitalo K, Boushel R, Hussein B, Rodrigues B
Flow-Induced Secretion of Endothelial Heparanase Regulates Cardiac Lipoprotein Lipase and Changes Following Diabetes.
Lee CS, Zhai Y, Shang R, Wong T, Mattison AJ, Cen HH, Johnson JD, Vlodavsky I, Hussein B, Rodrigues B
Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance.
Cen HH, Hussein B, Botezelli JD, Wang S, Zhang JA, Noursadeghi N, Jessen N, Rodrigues B, Timmons JA, Johnson JD
Cardiac-specific VEGFB overexpression reduces lipoprotein lipase activity and improves insulin action in rat heart.
Shang R, Lal N, Lee CS, Zhai Y, Puri K, Seira O, Boushel RC, Sultan I, Räsänen M, Alitalo K, Hussein B, Rodrigues B
Lipoprotein Lipase and Its Delivery of Fatty Acids to the Heart.
Shang R, Rodrigues B
Development and evaluation of novel nanoparticle formulations for therapeutic genome editing
Principal investigators: Ross, Colin J; Blakney, Anna
Keywords: Animal Models; Base Editor; Gene Editing; Genetic Disease; Lipid Nanoparticle; Nanoparticle; Prime Editor
Development and evaluation of novel nanoparticle formulations for therapeutic genome editing
Principal investigators: Ross, Colin J; Blakney, Anna
Keywords: Animal Models; Base Editor; Gene Editing; Genetic Disease; Lipid Nanoparticle; Nanoparticle; Prime Editor
Role of cardiac lipoprotein lipase in diabetic heart disease.
Principal investigators: Rodrigues, Brian B
Keywords: Cardiac Metabolism; Diabetic Cardiomyopathy; Lipoprotein Lipase
Role of VEGFB in the cardiovascular complications of diabetes.
Principal investigators: Rodrigues, Brian B
Keywords: Cardiac Metabolism; Diabetic Cardiomyopathy; Molecular Signaling; Vascular Endothelial Growth Factor B (Vegfb)
Role of cardiac lipoprotein lipase in diabetic heart disease.
Principal investigators: Rodrigues, Brian B
Keywords: Cardiac Metabolism; Diabetic Cardiomyopathy; Lipoprotein Lipase
Endothelial heparanase regulation of cardiac metabolism
Principal investigators: Rodrigues, Brian B
Keywords: Cardiac Metabolism; Heparanase; Lipoprotein Lipase; Lipotoxicity; Vegf
Regulation of endothelial heparanase following diabetes
Principal investigators: Rodrigues, Brian B
Keywords: Cardiac Metabolism; Endothelial Cells; Fatty Acid; Heparanase; Hyperglycemia; Lipoprotein Lipase
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Brian Rodrigues and Sanjoy Ghosh: 13 shared papers
- Brian Rodrigues and Ying Wang: 13 shared papers
- Guang Sun and Dake Qi: 5 shared papers
- Ismail Laher and Sanjoy Ghosh: 4 shared papers
- Brian Rodrigues and Corey Nislow: 3 shared papers
- Brian Rodrigues and Thomas Pulinilkunnil: 3 shared papers
- Dake Qi and Dake Qi: 3 shared papers
- Corey Nislow and Thomas Pulinilkunnil: 2 shared papers
- Guang Sun and Dake Qi: 2 shared papers
- Guang Sun and John McGuire: 2 shared papers
- Dake Qi and John McGuire: 2 shared papers
- John McGuire and Dake Qi: 2 shared papers
- Lucy Marzban and Brian Rodrigues: 1 shared paper
- Brian Rodrigues and Ismail Laher: 1 shared paper
- Brian Rodrigues and Guang Sun: 1 shared paper
- Brian Rodrigues and Dake Qi: 1 shared paper
- Brian Rodrigues and Marc Surette: 1 shared paper
- Brian Rodrigues and John McGuire: 1 shared paper
- Brian Rodrigues and Dake Qi: 1 shared paper
- Sanjoy Ghosh and Ying Wang: 1 shared paper
- Marc Surette and Thomas Pulinilkunnil: 1 shared paper
- Cellular and Molecular Pharmacology
- Biology
- Pathology and Laboratory Medicine
- Biochemistry and Molecular Biology
- Pharmacy
- Biomedical Sciences
- Genetics
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Ying Wang
Pathology and Laboratory Medicine
13 shared papers, latest 2015
Sanjoy Ghosh
Biology
13 shared papers, latest 2019
Thomas Pulinilkunnil
Biochemistry and Molecular Biology
3 shared papers, latest 2020
Corey Nislow
Faculty
3 shared papers, latest 2019
John McGuire
Department of Medical Biophysics
1 shared papers, latest 2024
Ismail Laher
Pediatrics
1 shared papers, latest 2009
Dake Qi
Pharmacy
1 shared papers, latest 2024
Guang Sun
Genetics
1 shared papers, latest 2024
Dake Qi
Biomedical Sciences
1 shared papers, latest 2024
Marc Surette
Chimie/Biochimie
1 shared papers, latest 2020
Lucy Marzban
Surgery
1 shared papers, latest 2009
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