Faculty profile

Wyeth Wasserman

ResearcherMedical GeneticsUniversity of British Columbia

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.

Wyeth Wasserman

Researcher

Medical Genetics

Health Sciences

University of British Columbia

Vancouver, British Columbia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
3 publications in the last five years, latest in 2024.
Principal investigator on 8 research grants (6 CIHR, 2 NSERC), most recently in 2022.
Supervised 9 trainees who won CIHR awards, most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Bioinformatics Discovery Global Developmental Delay Inborn Errors Of Metabolism Intellectual Disability Knowledge Translation Metabolomics Whole Exome Sequencing

Latest papers

Caregiver and Youth Characteristics That Influence Trust in Digital Health Platforms in Pediatric Care: Mixed Methods Study.
Journal of medical Internet research · 2024
Using human induced pluripotent stem cell-derived cardiomyocytes to understand the mechanisms driving cardiomyocyte maturation.
Frontiers in cardiovascular medicine · 2022
Genome-wide sequencing and the clinical diagnosis of genetic disease: The CAUSES study.
HGG advances · 2022

All 8 publications

Latest funding

Using Human Data to Identify Gene Regulatory Networks Involved in Oligodendrocyte Differentiation and Myelination in Health and Multiple Sclerosis
CIHR · 2024 · Supervisor
$210,000
Functional characterization of genomic DNA elements regulating epigenetic silencing
CIHR · 2023 · Co-investigator
$1,250,775
Precise Treatment for Pediatric Diabetes: Providing the right care, for the right patient, at the right time, over time
CIHR · 2022 · Principal investigator
$1,750,000

All 33 grants and awards

8 publications.

Caregiver and Youth Characteristics That Influence Trust in Digital Health Platforms in Pediatric Care: Mixed Methods Study.

Chow E, Virani A, Pinkney S, Abdulhussein FS, van Rooij T, Görges M, Wasserman W, Bone J, Longstaff H, Amed S

Journal of medical Internet research2024

DOI: 10.2196/53657 PMID: 39467279

Using human induced pluripotent stem cell-derived cardiomyocytes to understand the mechanisms driving cardiomyocyte maturation.

Hamledari H, Asghari P, Jayousi F, Aguirre A, Maaref Y, Barszczewski T, Ser T, Moore E, Wasserman W, Klein Geltink R, Teves S, Tibbits GF

Frontiers in cardiovascular medicine2022

DOI: 10.3389/fcvm.2022.967659 PMID: 36061558

Genome-wide sequencing and the clinical diagnosis of genetic disease: The CAUSES study.

Elliott AM, Adam S, du Souich C, Lehman A, Nelson TN, van Karnebeek C, Alderman E, Armstrong L, Aubertin G, Blood K, Boelman C, Boerkoel C, Bretherick K, Brown L, Chijiwa C, Clarke L, Couse M, Creighton S, Watts-Dickens A, Gibson WT, Gill H, Tarailo-Graovac M, Hamilton S, Heran H, Horvath G, Huang L, Hulait GK, Koehn D, Lee HK, Lewis S, Lopez E, Louie K, Niederhoffer K, Matthews A, Meagher K, Peng JJ, Patel MS, Race S, Richmond P, Rupps R, Salvarinova R, Seath K, Selby K, Steinraths M, Stockler S, Tang K, Tyson C, van Allen M, Wasserman W, Mwenifumbo J, Friedman JM

HGG advances2022

DOI: 10.1016/j.xhgg.2022.100108 PMID: 35599849

Human progranulin-expressing mice as a novel tool for the development of progranulin-modulating therapeutics.

Petkau TL, Life B, Lu G, Yang J, Fornes O, Wasserman W, Simpson EM, Leavitt BR

Neurobiology of disease2021

DOI: 10.1016/j.nbd.2021.105314 PMID: 33636385

metPropagate: network-guided propagation of metabolomic information for prioritization of metabolic disease genes.

Graham Linck EJ, Richmond PA, Tarailo-Graovac M, Engelke U, Kluijtmans LAJ, Coene KLM, Wevers RA, Wasserman W, van Karnebeek CDM, Mostafavi S

NPJ genomic medicine2020

DOI: 10.1038/s41525-020-0132-5 PMID: 32637154

Genome sequencing reveals a novel genetic mechanism underlying dihydropyrimidine dehydrogenase deficiency: A novel missense variant c.1700G>A and a large intragenic inversion in DPYD spanning intron 8 to intron 12.

van Kuilenburg ABP, Tarailo-Graovac M, Meijer J, Drogemoller B, Vockley J, Maurer D, Dobritzsch D, Ross CJ, Wasserman W, Meinsma R, Zoetekouw L, van Karnebeek CDM

Human mutation2018

DOI: 10.1002/humu.23538 PMID: 29691939

The NeuroDevNet Neuroinformatics Core.

Portales-Casamar E, Evans A, Wasserman W, Pavlidis P

Seminars in pediatric neurology2011

DOI: 10.1016/j.spen.2011.02.001 PMID: 21575836

ORegAnno: an open-access community-driven resource for regulatory annotation.

Griffith OL, Montgomery SB, Bernier B, Chu B, Kasaian K, Aerts S, Mahony S, Sleumer MC, Bilenky M, Haeussler M, Griffith M, Gallo SM, Giardine B, Hooghe B, Van Loo P, Blanco E, Ticoll A, Lithwick S, Portales-Casamar E, Donaldson IJ, Robertson G, Wadelius C, De Bleser P, Vlieghe D, Halfon MS, Wasserman W, Hardison R, Bergman CM, Jones SJ, Open Regulatory Annotation Consortium

Nucleic acids research2008

DOI: 10.1093/nar/gkm967 PMID: 18006570

Using Human Data to Identify Gene Regulatory Networks Involved in Oligodendrocyte Differentiation and Myelination in Health and Multiple Sclerosis

SupervisorCIHR2024CIHR Fellowship

Principal investigators: Van Horebeek, Lies A

Keywords: Chemical Compound Screening; Computational Analysis; Multiple Sclerosis; Oligodendrocytes And Myelination; Reanalysis Of Publicly Available Data; Regulatory Genetics; Single-Cell Rna-Seq

$210,000

Functional characterization of genomic DNA elements regulating epigenetic silencing

Co-investigatorCIHR2023Project Grant

Principal investigators: Brown, Carolyn J

Keywords: Bioinformatics; Ctcf; Dna Methylation; Epigenetics; Escape From Silencing; Heterochromatin; Transcription Factors; Transcription Regulation; Transgenes; X-Chromosome Inactivation

$1,250,775

Precise Treatment for Pediatric Diabetes: Providing the right care, for the right patient, at the right time, over time

Principal investigatorCIHR2022Team Grant: CIHR-JDRF Type 1 Diabetes and Precision Medicine

Principal investigators: Amed, Shazhan; Clements, Mark A; Tang, Tricia S; Wasserman, Wyeth W

Keywords: Digital Health; Pediatrics; Personalized Care; Precision Medicine; Type 1 Diabetes

$1,750,000

Deep Learning-Based Design of Synthetic Promoters for Oligodendroglia-Specific Expression

Nominated PICIHR2022Operating Grant - PA: Genetics (Bridge Funding: Research Priorities)

Principal investigators: Wasserman, Wyeth W

Keywords: Bioinformatics; Computational Biology; Gene Expression; Gene Therapy; Genome Regulation; Genomics; Regenerative Medicine; Stem Cell; Transcription Factors

$100,000

Local Computing Infrastructure for Large Scale Genomic Analysis

Co-investigatorNSERC2020Research Tools and Instruments

Principal investigators: Mostafavi, Sara

$150,000

Lentiviral infusion as a universal approach for genetically modified immune effector cell therapies.

Co-investigatorCIHR2020Project Grant

Principal investigators: Holt, Rob

Keywords: Cancer Immunotherapy; Car-T; Gene Expression; Gene Therapy; Gene Transfer Vectors; Immune Effector Cells; Lentivirus; Leukemia; Lymphoma; Synthetic Promoters

$642,600

Generation of a functionally robust stem cell based therapy for type 1 diabetes

Co-investigatorCIHR2020Team Grant: CIHR-JDRF-Accelerating Stem Cell-Based Therapies for Type 1 Diabetes

Principal investigators: Lynn, Francis C; Bruin, Jennifer E; Levings, Megan K; MacDonald, Patrick E; Verchere, Bruce C

Keywords: Embryonic Stem Cells; Functional Maturation; Genome Editing; Insulin Producing Cells; Insulin Secretion; Pancreatic Islets; Single Cell Analyses; Transplantation

$1,494,952

Be FAIR and CARE: Operationalizing responsible Indigenous data sharing to benefit patients with rare diseases

Co-investigatorCIHR2020Genomics and Precision Health Top-up

Principal investigators: Caron, Nadine R; Arbour, Laura T; Reading, Jeffrey L

Keywords: Data Sharing; Data Sovereignty; Ethics; Genomics; Indigenous

$100,000

GenCOUNSEL

Co-investigatorCIHR2020Genomics and Precision Health Top-up

Principal investigators: Elliott, Alison M; Austin, Jehannine C; Knoppers, Bartha M; Lynd, Larry D

Keywords: Genetic Counselling

$100,000

Functional characterization of genomic DNA elements regulating epigenetic silencing

Co-investigatorCIHR2018Project Grant

Principal investigators: Brown, Carolyn J

Keywords: Bioinformatics; Ctcf; Dna Methylation; Embryonic Stem Cells; Epigenetic Gene Regulation; Gfp Reporter; Mouse Model; Transcription Factors; X-Chromosome Inactivation; Yy1

$971,550

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Wyeth Wasserman

Research

Latest papers

Latest funding

Caregiver and Youth Characteristics That Influence Trust in Digital Health Platforms in Pediatric Care: Mixed Methods Study.

Using human induced pluripotent stem cell-derived cardiomyocytes to understand the mechanisms driving cardiomyocyte maturation.

Genome-wide sequencing and the clinical diagnosis of genetic disease: The CAUSES study.

Human progranulin-expressing mice as a novel tool for the development of progranulin-modulating therapeutics.

metPropagate: network-guided propagation of metabolomic information for prioritization of metabolic disease genes.

Genome sequencing reveals a novel genetic mechanism underlying dihydropyrimidine dehydrogenase deficiency: A novel missense variant c.1700G>A and a large intragenic inversion in DPYD spanning intron 8 to intron 12.

The NeuroDevNet Neuroinformatics Core.

ORegAnno: an open-access community-driven resource for regulatory annotation.

Using Human Data to Identify Gene Regulatory Networks Involved in Oligodendrocyte Differentiation and Myelination in Health and Multiple Sclerosis

Functional characterization of genomic DNA elements regulating epigenetic silencing

Precise Treatment for Pediatric Diabetes: Providing the right care, for the right patient, at the right time, over time

Deep Learning-Based Design of Synthetic Promoters for Oligodendroglia-Specific Expression

Local Computing Infrastructure for Large Scale Genomic Analysis

Lentiviral infusion as a universal approach for genetically modified immune effector cell therapies.

Generation of a functionally robust stem cell based therapy for type 1 diabetes

Be FAIR and CARE: Operationalizing responsible Indigenous data sharing to benefit patients with rare diseases

GenCOUNSEL

Functional characterization of genomic DNA elements regulating epigenetic silencing

Frequent collaborators

Maja Tarailo-Graovac

Sara Mostafavi

Edwin Moore

Paul Pavlidis

Sheila Teves

Ramon Klein Geltink

Britt Drogemoller

Shazhan Amed

Clara van Karnebeek

Sylvia Stockler