This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Immunological and prognostic impact of NRF2 in high grade serous ovarian cancer.
Genes and immunity · 2026 · senior author
Editorial: The foundational components and elements of plant foods for neurological nutrition and well-being.
Frontiers in nutrition · 2026 · senior author
SMARCA4 loss reprograms p300 chromatin occupancy to subvert p53-mediated transcriptional repression in ovarian small cell carcinoma.
Nature communications · 2026
Latest funding
- $1,120,726
DICER1 tumour predisposition syndrome: dissecting the oncogenic mechanisms with a novel lineage-trackable genetically engineered mouse model
CIHR · 2024 · Co-investigator
- $1,116,900
p300 histone acetyltransferase-dependency in SWI/SNF-deficient cancers: mechanisms and therapeutic implications
CIHR · 2024 · Co-investigator
- $1,143,675
Leveraging Epigenetic Reprogramming for Targeted Therapy in ARID1A/ARID1B Dual-Deficient Cancers
CIHR · 2024 · Nominated PI
49 publications.
Immunological and prognostic impact of NRF2 in high grade serous ovarian cancer.
Hamad SH, Katz C, Toma H, Murakami K, Bendjilali N, Zhu G, Shojaei H, Fang L, Leung S, Koebel M, Karaduman H, Abinader O, Mitra R, Krill L, Chu C, Warshal DP, Wang Y
Editorial: The foundational components and elements of plant foods for neurological nutrition and well-being.
Tang C, Li J, Wang Y
SMARCA4 loss reprograms p300 chromatin occupancy to subvert p53-mediated transcriptional repression in ovarian small cell carcinoma.
Aceto G, Liu K, Arabzadeh A, Tsai S, Xue Y, Monast A, Pilon V, Han M, Morin G, Pavlakis K, Fu L, Park M, Foulkes WD, Wang Y, Huang S
Co-targeting cystathionine gamma-lyase and mTOR: a promising therapeutic strategy in clear cell ovarian cancer.
Wei L, El-Naggar AM, Li Y, Ding Y, Li E, Lam T, Wang Y, Turgu B, Huntsman DG
Spatial single cell transcriptomic analysis informs tumor developmental hierarchy of DICER1 syndrome related sarcoma.
Kommoss FKF, Zhang JYH, Lynch BJ, Chen SY, Senz J, Moscovitz Y, Hill LA, Ma D, Scott RW, Bush J, Chen KS, Roth A, von Deimling A, Foulkes WD, Morin GB, Underhill TM, Wang Y, Huntsman DG
Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas.
St Laurent JD, Xu GD, Ying AW, Gokbayrak B, Patil A, Paulo JA, Cervantes KS, Chen S, Feng WW, Sankar A, Samé Guerra DD, Qi J, Neel DS, Hornick JL, Kolin DL, Gygi SP, Hunstman DG, Wang Y, Kadoch C
Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas.
St Laurent JD, Xu GD, Ying AW, Gokbayrak B, Patil A, Paulo JA, Cervantes KS, Chen S, Feng WW, Sankar A, Guerra DDS, Qi J, Neel DS, Hornick JL, Kolin DL, Gygi SP, Hunstman DG, Wang Y, Kadoch C
SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer.
Zhu X, Fu Z, Aceto G, St-Germain J, Liu K, Arabzadeh A, Qi Y, Xue Y, Witkowski L, Graulich E, Steinberger J, Misirlioglu S, Bassani N, Sansal R, Yasmeen A, Morin G, Guo J, Monast A, Pilon V, Valachová A, Pavlakis K, Fu L, Gotlieb WH, McCluggage WG, Huntsman D, Bishop AJR, Levine DA, Park M, Wang Y, Raught B, Foulkes WD, Huang S
Molecular subtyping of endometrial carcinoma cell lines uncovers subtype-specific targetable vulnerabilities.
Li ES, Ho R, Tao R, Choi YWY, Shin CY, Chen SY, Gokbayrak B, Senz J, Yao B, Johnston L, Martin SD, Yang E, Carey MS, Hennessy BT, Huntsman DG, Klein Geltink RI, Hoang L, Wang Y
Loss of SMARCA4 Leads to Intron Retention and Generation of Tumor-Associated Antigens in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.
Raupach EA, Hegde AM, Garcia-Mansfield K, Alcantara M, Rose DL, Halperin RF, Orlando KA, Lang JD, Sharma R, David-Dirgo V, Facista SJ, Moore R, Kofman R, Jensen ZN, Zismann VL, Karnezis AN, Wang Y, Bennett LB, Whitsett TG, Kortylewski M, Hendricks WPD, Huntsman DG, Rodriguez-Rodriguez L, Weissman BE, Trent JM, Pirrotte P
DICER1 tumour predisposition syndrome: dissecting the oncogenic mechanisms with a novel lineage-trackable genetically engineered mouse model
Principal investigators: Huntsman, David G
Keywords: Cancer Predisposition; Dicer1 Tumor Predisposition Syndrome; Genetically Engineered Mouse Model; Mesenchymal Progenitor; Microrna Biogenesis; Sarcoma
p300 histone acetyltransferase-dependency in SWI/SNF-deficient cancers: mechanisms and therapeutic implications
Principal investigators: Huang, Sidong
Keywords: Histone Acetyltransferase; P300; Smarca4; Swi/Snf
Leveraging Epigenetic Reprogramming for Targeted Therapy in ARID1A/ARID1B Dual-Deficient Cancers
Principal investigators: Wang, Yemin
Keywords: Arid1a; Arid1b; Chromatin-Remodelling; Dedifferentiated Endometrial Cancer; Epigenetic Reprogramming; Swi/Snf
Exploit the metabolic vulnerabilities in SWI/SNF-deficient cancer
Principal investigators: Wang, Yemin
Keywords: Drug Response; Glucose; Glutamine; Metabolism; Oxidative Stress; Smarca2; Smarca4; Swi/Snf
Recurrent Somatic DICER1 Mutations: Functional Implication and Role in Oncogenesis
Principal investigators: Morin, Gregg B; Huntsman, David G
Keywords: Biochemistry; Bioinformatics; Cell Culture; Dicer1 Mutations And Cancer; Embryonic Development; Microrna; Oncogenesis; Rna Processing; Sequencing; Teratomas
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Oncology
- Urologic Sciences
- Obstetrics and Gynecology
- Biochemistry
- Microbiology and Immunology
- Medicine
- Research Institute
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Basile Tessier-Cloutier
Obstetrics and Gynecology
4 shared papers, latest 2025
Morag Park
Oncology
3 shared papers, latest 2026
Morag Park
Oncology
3 shared papers, latest 2026
Sidong Huang
Biochemistry
3 shared papers, latest 2026
Martin Gleave
Urologic Sciences
2 shared papers, latest 2025
Yuzhuo Wang
Urologic Sciences
2 shared papers, latest 2025
Martin Hirst
Microbiology and Immunology
2 shared papers, latest 2024
Brian Raught
Research Institute
1 shared papers, latest 2025
David Huntsman
Molecular Oncology
1 shared papers, latest 2025
Anne-Marie Mes-Masson
Medicine
1 shared papers, latest 2021
Christian Steidl
Experimental Therapeutics
1 shared papers, latest 2020
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.