Faculty profile

Sidong Huang

ResearcherBiochemistryMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Sidong Huang

Researcher

Biochemistry

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
21 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 11 research grants (11 CIHR), most recently in 2026.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Drug Resistance Targeted Cancer Therapy Cancer Predisposition Syndrome Microrna Processing Sarcoma Swi/Snf Smarca4 Functional Genetics

Latest papers

SMARCA4 loss reprograms p300 chromatin occupancy to subvert p53-mediated transcriptional repression in ovarian small cell carcinoma.
Nature communications · 2026 · senior author
ATR and PKMYT1 Inhibition Resensitizes a Subset of TNBC Patient-Derived Models to Carboplatin, Inducing Mitotic Catastrophe.
Cancer research communications · 2026
SMARCA4/2 loss reduces BCL-xL expression and confers a druggable MCL1 dependency in cancer.
NPJ precision oncology · 2026 · senior author

All 42 publications

Latest funding

Investigating and targeting pathogenic variants in DICER1-related tumour predisposition
CIHR · 2026 · Principal investigator
$1,338,908
Investigating and targeting pathogenic variants in DICER1 tumour predisposition syndrome
CIHR · 2024 · Principal investigator
$100,000
p300 histone acetyltransferase-dependency in SWI/SNF-deficient cancers: mechanisms and therapeutic implications
CIHR · 2024 · Nominated PI
$1,116,900

All 15 grants and awards

42 publications.

SMARCA4 loss reprograms p300 chromatin occupancy to subvert p53-mediated transcriptional repression in ovarian small cell carcinoma.

Aceto G, Liu K, Arabzadeh A, Tsai S, Xue Y, Monast A, Pilon V, Han M, Morin G, Pavlakis K, Fu L, Park M, Foulkes WD, Wang Y, Huang S

Nature communications2026Senior author

DOI: 10.1038/s41467-026-74204-8 PMID: 42297809

ATR and PKMYT1 Inhibition Resensitizes a Subset of TNBC Patient-Derived Models to Carboplatin, Inducing Mitotic Catastrophe.

Guay J, Kuasne H, Chabot C, Bozek K, Majedi Y, Buchanan M, Aguilar-Mahecha A, Bareke E, Ulmer B, Kong T, Yang K, Liao M, Elebute O, Guo R, Monast A, Morin G, Huang S, Park M, Basik M

Cancer research communications2026

DOI: 10.1158/2767-9764.crc-25-0044 PMID: 41973002

SMARCA4/2 loss reduces BCL-xL expression and confers a druggable MCL1 dependency in cancer.

Jiang J, Zhu X, Fu Z, Liao M, Arabzadeh A, Robert F, Monast A, Pilon V, Pavlakis K, Park M, Foulkes WD, Huang S

NPJ precision oncology2026Senior author

DOI: 10.1038/s41698-026-01350-z PMID: 41807550

Synthesis of long and functionally active RNAs facilitated by acetal levulinic ester chemistry.

Lyu Z, Katolik A, Yaseen I, Pater AA, Robert F, Huang S, Gagnon KT, Unrau PJ, Damha MJ

Nucleic acids research2026

DOI: 10.1093/nar/gkaf1525 PMID: 41548876

MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death.

Nguyen M, Collier JJ, Ignatenko O, Morin G, Goyon V, Janer A, Tiefensee Ribeiro C, Milnerwood AJ, Huang S, Desjardins M, McBride HM

Nature cell biology2025

DOI: 10.1038/s41556-025-01774-y PMID: 41083601

SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer.

Zhu X, Fu Z, Aceto G, St-Germain J, Liu K, Arabzadeh A, Qi Y, Xue Y, Witkowski L, Graulich E, Steinberger J, Misirlioglu S, Bassani N, Sansal R, Yasmeen A, Morin G, Guo J, Monast A, Pilon V, Valachová A, Pavlakis K, Fu L, Gotlieb WH, McCluggage WG, Huntsman D, Bishop AJR, Levine DA, Park M, Wang Y, Raught B, Foulkes WD, Huang S

Cancer research2025Senior author

DOI: 10.1158/0008-5472.can-24-3990 PMID: 40366633

TSC2 loss in neural progenitor cells suppresses mRNA translation of neurodevelopmental genes.

Martin P, Szkop KJ, Robert F, Bhattacharyya S, Beauchamp RL, Brenner J, Redmond NE, Huang S, Erdin S, Larsson O, Ramesh V

Brain : a journal of neurology2025

DOI: 10.1093/brain/awaf081 PMID: 40037376

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays.

Goldstein SI, Fan AC, Wang Z, Naineni SK, Cencic R, Garcia-Gutierrez SB, Patel K, Huang S, Brown LE, Emili A, Porco JA

Journal of proteome research2025

DOI: 10.1021/acs.jproteome.4c01129 PMID: 40077831

Curative timed NK cell-based immunochemotherapy aborts brain tumour recurrence driven by mesenchymal glioma stem cells.

Meehan B, Adnani L, Zhu X, Tawil N, Garnier D, Nakano I, Huang S, Rak J

Acta neuropathologica communications2025

DOI: 10.1186/s40478-025-01984-3 PMID: 40119461

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays.

Goldstein SI, Fan AC, Wang Z, Naineni SK, Cencic R, Garcia-Gutierrez SB, Patel K, Huang S, Brown LE, Emili A, Porco JA

bioRxiv : the preprint server for biology2024

DOI: 10.1101/2024.04.19.590252 PMID: 38659867

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Sidong Huang

Research

Latest papers

Latest funding

SMARCA4 loss reprograms p300 chromatin occupancy to subvert p53-mediated transcriptional repression in ovarian small cell carcinoma.

ATR and PKMYT1 Inhibition Resensitizes a Subset of TNBC Patient-Derived Models to Carboplatin, Inducing Mitotic Catastrophe.

SMARCA4/2 loss reduces BCL-xL expression and confers a druggable MCL1 dependency in cancer.

Synthesis of long and functionally active RNAs facilitated by acetal levulinic ester chemistry.

MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death.

SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer.

TSC2 loss in neural progenitor cells suppresses mRNA translation of neurodevelopmental genes.

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays.

Curative timed NK cell-based immunochemotherapy aborts brain tumour recurrence driven by mesenchymal glioma stem cells.

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays.

Frequent collaborators

Morag Park

Morag Park

Jerry Pelletier

Janusz Rak

Yasser Riazalhosseini

Yemin Wang

Mark Lathrop

Michael Witcher

ATILLA Omeroglu

William Lockwood

Ivan Topisirovic

Lynne-Marie Postovit

Shawn McGuirk

Mark Basik

Julie St-Pierre

Lynne-Marie Postovit

Jonathan Spicer

Anne-Claude Gingras

David Huntsman

Julie St-Pierre

David Dankort

Brian Raught

Arnim Pause

Anastasia Nijnik

Nada Jabado

Quaid Morris