This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Longitudinal single-cell analysis reveals RUNX1T1 as an early driver in treatment-induced neuroendocrine transdifferentiation.
bioRxiv : the preprint server for biology · 2025
Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025 · first author
Identification of the specific characteristics of neuroendocrine prostate cancer: Immune status, hub genes and treatment.
Translational oncology · 2025
Latest funding
- $944,776
Physiological and pathological regulation of GABAA receptor functions
CIHR · 2023 · Nominated PI
- $5,023,651
Regulation of postsynaptic expression and function of ionotropic neurotransmitter receptors
CIHR · 2016 · Nominated PI
- $955,625
Developing novel GluN2A-containing NMDAR-based stroke therapies
CIHR · 2016 · Nominated PI
11 publications.
Longitudinal single-cell analysis reveals RUNX1T1 as an early driver in treatment-induced neuroendocrine transdifferentiation.
Ni Y, Lin D, Shi M, Lin YY, Xue H, Dong X, Liu L, Sar F, Wu R, Morova T, Haegert A, Bell R, Pang X, Classen A, Wang Y, Chen J, Volik S, Bihan SL, Lack N, Ong C, Wang G, Zeng H, Collins C, Wang Y
Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation.
Wang Y, Xue H, Zhu X, Lin D, Chen Z, Dong X, Chen J, Shi M, Ni Y, Cao J, Wu R, Kang C, Pang X, Crea F, Lin YY, Collins CC, Gleave ME, Parolia A, Chinnaiyan A, Ong CJ, Wang Y
Identification of the specific characteristics of neuroendocrine prostate cancer: Immune status, hub genes and treatment.
Wang J, Wang Y, Zhou H, Yu G, Xu H, Gao D, Li M, Wang Y, Xu B
Transcription Factor Dynamics in Neuroendocrine Prostate Cancer Development.
Wang Y, Wang Y
The third symposium on treatment-induced neuroendocrine prostate cancer: insights and future directions.
Wang Y, Scurll J, Rascón IA, Cui C, Ni Y, Shi AM, Gangadharannambiar P, Wang Y, Akamatsu S, Beltran H, Cox M, Crea F, Daugaard M, Dong X, Haffner M, He H, Jachetti E, Kyprianou N, Li B, Ong CE, Rickman DS, Sen T, Zhu HH, Zoubeidi A, Gleave ME
Genomic alterations in neuroendocrine prostate cancer: A systematic review and meta-analysis.
Chen J, Shi M, Chuen Choi SY, Wang Y, Lin D, Zeng H, Wang Y
Patient-derived xenograft models of neuroendocrine prostate cancer.
Shi M, Wang Y, Lin D, Wang Y
Molecular events in neuroendocrine prostate cancer development.
Wang Y, Wang Y, Ci X, Choi SYC, Crea F, Lin D, Wang Y
ZRSR2 overexpression is a frequent and early event in castration-resistant prostate cancer development.
He H, Hao J, Dong X, Wang Y, Xue H, Qu S, Choi SYC, Ci X, Wang Y, Wu R, Shi M, Zhao X, Collins C, Lin D, Wang Y
Patient-derived Hormone-naive Prostate Cancer Xenograft Models Reveal Growth Factor Receptor Bound Protein 10 as an Androgen Receptor-repressed Gene Driving the Development of Castration-resistant Prostate Cancer.
Hao J, Ci X, Xue H, Wu R, Dong X, Choi SYC, He H, Wang Y, Zhang F, Qu S, Zhang F, Haegert AM, Gout PW, Zoubeidi A, Collins C, Gleave ME, Lin D, Wang Y
Physiological and pathological regulation of GABAA receptor functions
Principal investigators: Wang, Yu Tian
Keywords: Animal Studies; Brain Slices; Cell Biology; Electrophysiology; Epilepsy; Gaba-A Receptor; Glutamate
Regulation of postsynaptic expression and function of ionotropic neurotransmitter receptors
Principal investigators: Wang, Yu Tian
Keywords: Brain Slices; Cultured Neurons; Electrophysiology; Gabaa Receptor; Long-Term Depression; Long-Term Potentiation; Nmda Receptor; Receptor Trafficking; Synaptic Plasticity; Synaptic Transmission
Developing novel GluN2A-containing NMDAR-based stroke therapies
Principal investigators: Wang, Yu Tian
Keywords: Neuroscience Research; Neurotransmitters; Stroke
Regulation of postsynaptic expression and function of GABA-A receptors
Principal investigators: Wang, Yu Tian
Keywords: Brain Slices; Cell Biology; Cultured Neurons; Electrophysiology; Epilepsy; Gaba-A Receptor
Canadian Stroke Network (2006 Renewal Competition)
Principal investigators: Hakim, Antoine
Investigation into the molecular mechanisms of AMPAR trafficking following primary blast-induced mTBI
Principal investigators: Wang, Yu Tian
Keywords: Ampa Receptor; Animal Physiology; Blast Injury; Cell Biology; Endocytosis; Molecular Biology; Neurodegeneration; Receptor Trafficking; Therapeutics; Traumatic Brain Injury
Investigation into molecular mechanisms and physiological roles of activity-dependent AMPAR trafficking
Principal investigators: Wang, Yu Tian
Keywords: Ampa Receptor; Animal Physiology; Brain Slices; Cell Biology; Cultured Neurons; Electrophysiology; Exocytosis; Receptor Trafficking; Synaptic Plasticity; Synaptic Transmission
Role of PTEN nuclear translocation in NMDAR-mediated exciotoxic neuronal death in Huntington's Disease
Principal investigators: Girling, Kimberly D
Keywords: Cell Culture; Cell Signaling; Excitotoxicity; Huntington'S Disease; Neurodegeneration; Neuronal Death; Neuroscience; Nmda Receptors; Pharmacology And Therapeutics; Pten
Investigation into the molecular mechanisms mediating excitotoxicity - developing novel post-stroke therapies
Principal investigators: Wang, Yu Tian
Keywords: Excitotoxicity; Ischemic Neuronal Injury; Nmda Receptor; Pten; Stroke
From Down Syndrome to Alzheimer's Disease: the molecular mechanism underlying the dementia pathogenesis and the therapeutic potentials
Principal investigators: Song, Weihong; Li, Ting-Yu
Keywords: Alzheimer'S Disease; Amyloid; Bace1; Down Syndrome; Ltp And Ltd; Molecular Genetics; Transgenic And Knockout; Two-Photon Imaging
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Urologic Sciences
- Medicine/Neurology
- Pathology and Laboratory Medicine
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Yuzhuo Wang
Urologic Sciences
10 shared papers, latest 2025
Colin Collins
Urologic Sciences
3 shared papers, latest 2025
Amina Zoubeidi
Urologic Sciences
2 shared papers, latest 2024
Michael Cox
Urologic Sciences
1 shared papers, latest 2024
Mads Daugaard
Urologic Sciences
1 shared papers, latest 2024
Xuesen Dong
Urologic Sciences
1 shared papers, latest 2024
Gang Wang
Pathology and Laboratory Medicine
1 shared papers, latest 2025
Christopher Ong
Urologic Sciences
1 shared papers, latest 2025
Nathan Lack
Faculty
1 shared papers, latest 2025
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