Christopher Pascoe

Research

Airway Smooth Muscle Animal Model Asthma Developmental Origins Gestational Diabetes Rhoa Stem Cell Human

Latest papers

Alteration of oxidized phospholipids profile in bronchoalveolar lavage fluid collected from atopic individuals co-exposed to air pollution and allergen.
American journal of respiratory cell and molecular biology · 2026
Lifetime lung function trajectories and COPD: when the train derails.
The Lancet. Respiratory medicine · 2023
Slow Off-Rate Modified Aptamer (SOMAmer) Proteomic Analysis of Patient-Derived Malignant Glioma Identifies Distinct Cellular Proteomes.
International journal of molecular sciences · 2021

All 3 publications

Latest funding

Cigarette smoking as a modifiable risk factor for Rheumatoid Arthritis development in First Nations Peoples.
CIHR · 2026 · Co-investigator
$914,176
Cigarette smoking induced neutrophilic inflammation as a modifiable risk factor for Rheumatoid Arthritis in First Nations
CIHR · 2024 · Co-investigator
$100,000
Impact of exposure to hyperglycemia during pregnancy on offspring airway smooth muscle contractility and the activity of RhoA
CIHR · 2023 · Nominated PI
$784,125

All 9 grants and awards

3 publications.

01

Alteration of oxidized phospholipids profile in bronchoalveolar lavage fluid collected from atopic individuals co-exposed to air pollution and allergen.

Zhang AA, Ryu MH, Jha A, Pascoe C, Ravandi A, Halayko AJ, Carlsten C

American journal of respiratory cell and molecular biology2026

DOI: 10.1165/rcmb.2025-0303le PMID: 41072022

02

Lifetime lung function trajectories and COPD: when the train derails.

Bose S, Pascoe C, McEvoy C

The Lancet. Respiratory medicine2023

DOI: 10.1016/s2213-2600(22)00391-5 PMID: 36244395

03

Slow Off-Rate Modified Aptamer (SOMAmer) Proteomic Analysis of Patient-Derived Malignant Glioma Identifies Distinct Cellular Proteomes.

Thanasupawat T, Glogowska A, Pascoe C, Krishnan SN, Munir M, Begum F, Beiko J, Krcek J, Del Bigio MR, Pitz M, Shen Y, Spicer V, Coombs KM, Wilkins J, Hombach-Klonisch S, Klonisch T

International journal of molecular sciences2021

DOI: 10.3390/ijms22179566 PMID: 34502484

Cigarette smoking as a modifiable risk factor for Rheumatoid Arthritis development in First Nations Peoples.

Co-investigatorCIHR2026Project Grant

Principal investigators: O'Neil, Liam J

Keywords: Cigarette Smoking; Citrullination; Disease Risk; First Nations; Neutrophil Extracellular Traps; Preclinical; Proteomics; Rheumatoid Arthritis

$914,176

Cigarette smoking induced neutrophilic inflammation as a modifiable risk factor for Rheumatoid Arthritis in First Nations

Co-investigatorCIHR2024Project Grant - PA: Research in First Nations, Inuit and/or Métis Health

Principal investigators: O'Neil, Liam J

Keywords: Autoantibody; Cigarette Smoking; Citrullination; Collagen Induced Arthritis; First Nations; Neutrophil Extracellular Traps; Neutrophils; Proteomics; Rheumatoid Arthritis; Smoking Cessation

$100,000

Impact of exposure to hyperglycemia during pregnancy on offspring airway smooth muscle contractility and the activity of RhoA

Nominated PICIHR2023Project Grant

Principal investigators: Pascoe, Christopher D

Keywords: Airway Smooth Muscle; Animal Model; Asthma; Developmental Origins; Gestational Diabetes; Rhoa; Stem Cell

$784,125

Impact of maternal hyperglycemia on offspring airway smooth muscle contractility and the activity of RhoA.

Nominated PICIHR2022Project Grant

Principal investigators: Pascoe, Christopher D

Keywords: Airway Smooth Muscle; Animal Model; Asthma; Developmental Origins; Gestational Diabetes; Rhoa; Stem Cell

$100,000

Amniotic fluid as a mediator between maternal smoking and fetal lung health

Principal investigatorSSHRC2021New Frontiers in Research Fund - Exploration

Principal investigators: Pascoe, Christopher

Keywords: Environment Cigarettes Amniotic fluid Lung Inflammation Culture systems Epithelium Differentiation Development Pregnancy

$250,000

Elucidating the Role of the Hydroxyeicosatetraenoic Acid Family of Eicosanoids in Airway Smooth Muscle Physiology

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Pascoe, Christopher

$150,000

Elucidating the Role of the Hydroxyeicosatetraenoic Acid Family of Eicosanoids in Airway Smooth Muscle Physiology

Principal investigatorNSERC2020Discovery Launch Supplement

Principal investigators: Pascoe, Christopher

$12,500

Understanding the pathology of vaping associated lung damage in young adults

Nominated PICIHR2020Catalyst Grant: Health Effects of Vaping

Principal investigators: Pascoe, Christopher D

Keywords: Human; Inflammation; Lung Injury; Pathology; Pneumothorax; Prospective; Rna-Sequencing; Vaping; Young Adult

$100,000

Molecular adaptation to allergen exposure: sex-related differences in asthma

Co-investigatorCIHR2017Catalyst Grant: Sex as a Variable in Biomedical Research

Principal investigators: Mookherjee, Neeloffer

Keywords: Asthma; Biosignature; Human Controlled Exposure Model; Immune Response; Inflammation; Lung; Murine Model

$148,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Internal Medicine
Physiology and Pathophysiology
Human Anatomy & Cell Science
Other

Co-authors at University of Manitoba, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

John Wilkins

Internal Medicine

1 shared papers, latest 2021

Thomas Klonisch

Human Anatomy & Cell Science

1 shared papers, latest 2021

Marshall Pitz

Internal Medicine

1 shared papers, latest 2021

Sabine Hombach-Klonisch

Faculty

1 shared papers, latest 2021

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2023

Subject: Prospective PhD student: Airway Smooth Muscle Dear Professor Pascoe, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Alteration of oxidized phospholipids profile in bronchoalveolar lavage fluid collected from atopic individuals co-exposed to air pollution and allergen." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Impact of exposure to hyperglycemia during pregnancy on offspring airway smooth muscle contractility and the activity of RhoA" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]