Faculty profile

Sabine Hombach-Klonisch

ResearcherUniversity of Manitoba

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Manitoba directory, so their courses may be missing. Find their university profile.

Sabine Hombach-Klonisch

Researcher

Health Sciences

University of Manitoba

Winnipeg, Manitoba, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
17 publications in the last five years, latest in 2026.
Senior (last) author on 7 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (3 NSERC, 2 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Breast Cancer Upr

Latest papers

Neuroglial-Breast Cancer Crosstalk Shapes the Brain Metastatic Niche.
Cells · 2026 · first author
A customized affordable multiplexed immunofluorescence method visualizes early changes in the mouse brain microenvironment upon laser cytoreduction.
Frontiers in cellular neuroscience · 2025
The Brain-Penetrant Pan-ErbB Inhibitor Poziotinib Effectively Targets HER2+ Breast Cancer Brain Metastases.
Cancer research · 2025 · senior author

All 65 publications

Latest funding

HER2+ breast-to-brain metastasis and TME co-evolve in therapeutic resistance and recurrence
CIHR · 2024 · Nominated PI
$65,000
Novel functions of high mobility group A chromatin-binding factors
NSERC · 2024 · Principal investigator
$41,000
Laser Thermal Immunomodulation in the Brain
NSERC · 2021 · Co-investigator
$150,000

All 6 grants and awards

65 publications.

Neuroglial-Breast Cancer Crosstalk Shapes the Brain Metastatic Niche.

Hombach-Klonisch S, Hall E, Amin R, Fedora E, Vriend J, Pitz M, Klonisch T

Cells2026First author

DOI: 10.3390/cells15080735 PMID: 42041600

A customized affordable multiplexed immunofluorescence method visualizes early changes in the mouse brain microenvironment upon laser cytoreduction.

Shanmugam Anandhan S, Spence J, Begum F, Kaur N, Henderson D, Hombach-Klonisch S, Klonisch T

Frontiers in cellular neuroscience2025

DOI: 10.3389/fncel.2025.1553058 PMID: 40989806

The Brain-Penetrant Pan-ErbB Inhibitor Poziotinib Effectively Targets HER2+ Breast Cancer Brain Metastases.

Ippolitov D, Lin YH, Spence J, Glogowska A, Thanasupawat T, Beiko J, Del Bigio MR, Xu X, Wang AQ, Williams D, Calvo R, Kapoor A, Marugan JJ, Henderson MJ, Klonisch T, Hombach-Klonisch S

Cancer research2025Senior author

DOI: 10.1158/0008-5472.can-24-1793 PMID: 39932819

Distinct spatial N-glycan profiles reveal glioblastoma-specific signatures.

Angerstein AO, Young LEA, Thanasupawat T, Vriend J, Grimsley G, Lun X, Senger DL, Sinha N, Beiko J, Pitz M, Hombach-Klonisch S, Drake RR, Klonisch T

The Journal of pathology2025

DOI: 10.1002/path.6401 PMID: 39967571

An introduction to the special issue "9th International Conference on Relaxin and Related Peptides".

Bennett RG, Hombach-Klonisch S, Klonisch T, Wilson BC

Biochemical pharmacology2025

DOI: 10.1016/j.bcp.2025.116775 PMID: 39862991

Proteomic and cytokine profiling of a CTRP8-RXFP1 glioma mouse model.

Thanasupawat T, Mejia YP, Anandhan SS, Guo Y, Tiwana J, Fernando A, Glogowska A, Shafai T, daSilva S, Kaur N, Begum F, Zahedi R, Hombach-Klonisch S, Klonisch T

Biochemical pharmacology2025

DOI: 10.1016/j.bcp.2024.116722 PMID: 39709036

Emerging roles of High Mobility Group A (HMGA) family members in nuclear organization.

Singh M, Thanasupawat T, Klonisch T, Hombach-Klonisch S

Biochemistry and cell biology = Biochimie et biologie cellulaire2025Senior author

DOI: 10.1139/bcb-2025-0100 PMID: 41160894

C1QTNF Related protein 8 (CTRP8) is a marker of myeloid derived innate immune cell populations in the human breast cancer microenvironment.

Arreza L, Thanasupawat T, Krishnan SN, Kraljevic M, Klonisch T, Hombach-Klonisch S

Biochemical pharmacology2024Senior author

DOI: 10.1016/j.bcp.2024.116624 PMID: 39542181

Breast Tumor Metastasis and Its Microenvironment: It Takes Both Seed and Soil to Grow a Tumor and Target It for Treatment.

Bonni S, Brindley DN, Chamberlain MD, Daneshvar-Baghbadorani N, Freywald A, Hemmings DG, Hombach-Klonisch S, Klonisch T, Raouf A, Shemanko CS, Topolnitska D, Visser K, Vizeacoumar FJ, Wang E, Gibson SB

Cancers2024

DOI: 10.3390/cancers16050911 PMID: 38473273

Overcoming brain-derived therapeutic resistance in HER2+ breast cancer brain metastasis.

Ippolitov D, Lin YH, Spence J, Glogowska A, Thanasupawat T, Beiko J, Del Bigio MR, Xu X, Wang A, Calvo R, Kapoor A, Marugan JJ, Henderson MJ, Klonisch T, Hombach-Klonisch S

bioRxiv : the preprint server for biology2024Senior author

DOI: 10.1101/2024.02.19.581073 PMID: 38529509

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Sabine Hombach-Klonisch

Research

Latest papers

Latest funding

Neuroglial-Breast Cancer Crosstalk Shapes the Brain Metastatic Niche.

A customized affordable multiplexed immunofluorescence method visualizes early changes in the mouse brain microenvironment upon laser cytoreduction.

The Brain-Penetrant Pan-ErbB Inhibitor Poziotinib Effectively Targets HER2+ Breast Cancer Brain Metastases.

Distinct spatial N-glycan profiles reveal glioblastoma-specific signatures.

An introduction to the special issue "9th International Conference on Relaxin and Related Peptides".

Proteomic and cytokine profiling of a CTRP8-RXFP1 glioma mouse model.

Emerging roles of High Mobility Group A (HMGA) family members in nuclear organization.

C1QTNF Related protein 8 (CTRP8) is a marker of myeloid derived innate immune cell populations in the human breast cancer microenvironment.

Breast Tumor Metastasis and Its Microenvironment: It Takes Both Seed and Soil to Grow a Tumor and Target It for Treatment.

Overcoming brain-derived therapeutic resistance in HER2+ breast cancer brain metastasis.

HER2+ breast-to-brain metastasis and TME co-evolve in therapeutic resistance and recurrence

Novel functions of high mobility group A chromatin-binding factors

Laser Thermal Immunomodulation in the Brain

The unfolded protein response (UPR) in early brain metastasis.

Molecular determinants of thyroid cell functional plasticity

Biological impact of xenobiotics in the female reproductive tract

Frequent collaborators

Thomas Klonisch

Marshall Pitz

Yvonne Myal

Sabine Mai

Leigh Murphy

Elissavet Kardami

Mohsen Akbari

Edwin Wang

Christopher Pascoe

Tanveer Sharif

Laura Trinkle-Mulcahy

Francis Lin

Andrew Halayko

John Wilkins

Jean-Eric Ghia

Chris Wiebe

Claudio Rigatto

Prashen Chelikani

Julie Ho

Johan van Lierop

Andrew Freywald