Faculty profile

Thomas Issekutz

ResearcherPediatricsDalhousie University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Dalhousie University directory, so their courses and email address may be missing. Find their university profile.

Thomas Issekutz

Researcher

Pediatrics

Health Sciences

Dalhousie University

Halifax, Nova Scotia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
1 publication in the last five years, latest in 2026.
Principal investigator on 2 research grants (2 CIHR), most recently in 2018.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Arthritis Human Immunology Immunogenetics Innate Immunity Interferons Lupus Cell Migration Chemokines

Latest papers

Three Doses and Six Months Later: Real-World SARS-CoV-2 Specific Humoral and Cell-Mediated Immunity in Children With Inborn Errors of Immunity.
Journal of clinical immunology · 2026
IPEX Syndrome with Normal FOXP3 Protein Expression in Treg Cells in an Infant Presenting with Intractable Diarrhea as a Single Symptom.
Case reports in immunology · 2020
Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization.
Science signaling · 2019

All 12 publications

Latest funding

Defining critical pathways of innate immunity for precision therapy of autoimmune diseases
CIHR · 2018 · Nominated PI
$20,000
Restitution Enhancement in Arthritis and Chronic Heart disease
CIHR · 2013 · Principal investigator
$2,337,154
The Canadian Regenerative Medicine Network (CRM-Net) / Le Réseau Canadien de Médecine Régénérative
NSERC · 2003 · Co-investigator
$25,000

All 3 grants and awards

12 publications.

Three Doses and Six Months Later: Real-World SARS-CoV-2 Specific Humoral and Cell-Mediated Immunity in Children With Inborn Errors of Immunity.

Porto LLTN, Yazji D, Unninayar D, Decaluwe H, Derfalvi B, Palma A, Issekutz T, Kalashnikova T, Murguía-Favela L, Pham-Huy A, Rubin T, Suresh S, Upton J, Wright NAM, Chapdelaine H, Falcone EL, Top KA, Sadarangani M, Vinh DC, Barrett L, Oldford S, Langlois MA, Arnold C, Zhang T, Ramsay T, Cowan J, VISID study investigators

Journal of clinical immunology2026

DOI: 10.1007/s10875-026-02021-1 PMID: 42034835

IPEX Syndrome with Normal FOXP3 Protein Expression in Treg Cells in an Infant Presenting with Intractable Diarrhea as a Single Symptom.

Al Maawali A, Derfalvi B, Van Limbergen J, Issekutz A, Issekutz T, Ghandourah H, Rashid M

Case reports in immunology2020

DOI: 10.1155/2020/9860863 PMID: 32963853

Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization.

Eckstein M, Vaeth M, Aulestia FJ, Costiniti V, Kassam SN, Bromage TG, Pedersen P, Issekutz T, Idaghdour Y, Moursi AM, Feske S, Lacruz RS

Science signaling2019

DOI: 10.1126/scisignal.aav4663 PMID: 31015290

T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency.

Brigida I, Zoccolillo M, Cicalese MP, Pfajfer L, Barzaghi F, Scala S, Oleaga-Quintas C, Álvarez-Álvarez JA, Sereni L, Giannelli S, Sartirana C, Dionisio F, Pavesi L, Benavides-Nieto M, Basso-Ricci L, Capasso P, Mazzi B, Rosain J, Marcus N, Lee YN, Somech R, Degano M, Raiola G, Caorsi R, Picco P, Moncada Velez M, Khourieh J, Arias AA, Bousfiha A, Issekutz T, Issekutz A, Boisson B, Dobbs K, Villa A, Lombardo A, Neven B, Moshous D, Casanova JL, Franco JL, Notarangelo LD, Scielzo C, Volpi S, Dupré L, Bustamante J, Gattorno M, Aiuti A

Blood2018

DOI: 10.1182/blood-2018-07-863431 PMID: 30254128

ORAI1 mutations abolishing store-operated Ca2+ entry cause anhidrotic ectodermal dysplasia with immunodeficiency.

Lian J, Cuk M, Kahlfuss S, Kozhaya L, Vaeth M, Rieux-Laucat F, Picard C, Benson MJ, Jakovcevic A, Bilic K, Martinac I, Stathopulos P, Kacskovics I, Vraetz T, Speckmann C, Ehl S, Issekutz T, Unutmaz D, Feske S

The Journal of allergy and clinical immunology2018

DOI: 10.1016/j.jaci.2017.10.031 PMID: 29155098

Severe, persistent, and fatal T-cell immunodeficiency following therapy for infantile leukemia.

Geerlinks AV, Issekutz T, Wahlstrom JT, Sullivan KE, Cowan MJ, Dvorak CC, Fernandez CV

Pediatric blood & cancer2016

DOI: 10.1002/pbc.26108 PMID: 27354010

Direct evidence for activated CD8+ T cell transmigration across portal vein endothelial cells in liver graft rejection.

Kariya T, Ueta H, Xu XD, Koga D, Ezaki T, Yu E, Kusumi S, Kitazawa Y, Sawanobori Y, Ushiki T, Issekutz T, Matsuno K

Journal of gastroenterology2016

DOI: 10.1007/s00535-016-1169-1 PMID: 26891909

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid.

Schläger C, Körner H, Krueger M, Vidoli S, Haberl M, Mielke D, Brylla E, Issekutz T, Cabañas C, Nelson PJ, Ziemssen T, Rohde V, Bechmann I, Lodygin D, Odoardi F, Flügel A

Nature2016

DOI: 10.1038/nature16939 PMID: 26863192

Mast cells protect against Pseudomonas aeruginosa-induced lung injury.

Junkins RD, Carrigan SO, Wu Z, Stadnyk AW, Cowley E, Issekutz T, Berman J, Lin TJ

The American journal of pathology2014

DOI: 10.1016/j.ajpath.2014.05.009 PMID: 25043620

Early fibroblast progenitor cell migration to the AngII-exposed myocardium is not CXCL12 or CCL2 dependent as previously thought.

Falkenham A, Sopel M, Rosin N, Lee TD, Issekutz T, Légaré JF

The American journal of pathology2013

DOI: 10.1016/j.ajpath.2013.04.011 PMID: 23731726

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Thomas Issekutz

Research

Latest papers

Latest funding

Three Doses and Six Months Later: Real-World SARS-CoV-2 Specific Humoral and Cell-Mediated Immunity in Children With Inborn Errors of Immunity.

IPEX Syndrome with Normal FOXP3 Protein Expression in Treg Cells in an Infant Presenting with Intractable Diarrhea as a Single Symptom.

Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization.

T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency.

ORAI1 mutations abolishing store-operated Ca2+ entry cause anhidrotic ectodermal dysplasia with immunodeficiency.

Severe, persistent, and fatal T-cell immunodeficiency following therapy for infantile leukemia.

Direct evidence for activated CD8+ T cell transmigration across portal vein endothelial cells in liver graft rejection.

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid.

Mast cells protect against Pseudomonas aeruginosa-induced lung injury.

Early fibroblast progenitor cell migration to the AngII-exposed myocardium is not CXCL12 or CCL2 dependent as previously thought.

Defining critical pathways of innate immunity for precision therapy of autoimmune diseases

Restitution Enhancement in Arthritis and Chronic Heart disease

The Canadian Regenerative Medicine Network (CRM-Net) / Le Réseau Canadien de Médecine Régénérative

Frequent collaborators

Beata Derfalvi

Tong-Jun Lin

Brent Johnston

Marc-André Langlois

Manish Sadarangani

Peter Stathopulos

Juthaporn Cowan

Jason Berman