Faculty profile
Peter Stathopulos
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Read how they describe their research on their Western University profile.
Latest papers
DNA damage-inducible transcript 3 positively regulates RIPK1-mediated necroptosis.
Cell death and differentiation · 2025
ORAI1 mutations abolishing store-operated Ca2+ entry cause anhidrotic ectodermal dysplasia with immunodeficiency.
The Journal of allergy and clinical immunology · 2018
A dual mechanism promotes switching of the Stormorken STIM1 R304W mutant into the activated state.
Nature communications · 2018
Latest funding
- $768,826
Allosteric landscape of mitochondrial calcium uniporter (MCU) regulation by MCU regulator-1 and redox signaling: identifying conformational triggers of cardiomyocyte injury.
CIHR · 2026 · Nominated PI
- $849,150
Annexin A5 as a treatment for COVID-19
CIHR · 2021 · Principal investigator
- $150,000
Bio--Layer interferometry system for biomolecular interaction analysis
NSERC · 2021 · Co-investigator
5 publications.
DNA damage-inducible transcript 3 positively regulates RIPK1-mediated necroptosis.
Ni R, Cao T, Ji X, Peng A, Zhang Z, Fan GC, Stathopulos P, Chakrabarti S, Su Z, Peng T
ORAI1 mutations abolishing store-operated Ca2+ entry cause anhidrotic ectodermal dysplasia with immunodeficiency.
Lian J, Cuk M, Kahlfuss S, Kozhaya L, Vaeth M, Rieux-Laucat F, Picard C, Benson MJ, Jakovcevic A, Bilic K, Martinac I, Stathopulos P, Kacskovics I, Vraetz T, Speckmann C, Ehl S, Issekutz T, Unutmaz D, Feske S
A dual mechanism promotes switching of the Stormorken STIM1 R304W mutant into the activated state.
Fahrner M, Stadlbauer M, Muik M, Rathner P, Stathopulos P, Ikura M, Müller N, Romanin C
MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.
Tomar D, Dong Z, Shanmughapriya S, Koch DA, Thomas T, Hoffman NE, Timbalia SA, Goldman SJ, Breves SL, Corbally DP, Nemani N, Fairweather JP, Cutri AR, Zhang X, Song J, Jaña F, Huang J, Barrero C, Rabinowitz JE, Luongo TS, Schumacher SM, Rockman ME, Dietrich A, Merali S, Caplan J, Stathopulos P, Ahima RS, Cheung JY, Houser SR, Koch WJ, Patel V, Gohil VM, Elrod JW, Rajan S, Madesh M
A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).
Fahrner M, Muik M, Schindl R, Butorac C, Stathopulos P, Zheng L, Jardin I, Ikura M, Romanin C
Allosteric landscape of mitochondrial calcium uniporter (MCU) regulation by MCU regulator-1 and redox signaling: identifying conformational triggers of cardiomyocyte injury.
Principal investigators: Stathopulos, Peter B
Keywords: Calcium Signaling; Heart Disease; Mcu Dominant Negative Beta Subunit; Mcu Regulating Protein 1; Mitochondrial Calcium Uniporter; Nitric Oxide; Protein Allostery
Annexin A5 as a treatment for COVID-19
Principal investigators: Feng, Qingping; Barr, Stephen D; Stathopulos, Peter B
Keywords: Covid-19; Infection; Inflammation
Bio--Layer interferometry system for biomolecular interaction analysis
Principal investigators: Choy, Wing-Yiu
Interrogating the structural basis for protein interactions underlying mitochondrial calcium uniporter regulation in cardiomyocytes.
Principal investigators: Stathopulos, Peter B
Keywords: Calcium Signaling; Mcu Regulating Protein-1; Mitochondrial Calcium Uniporter; Myocardial Infarction; Protein Allostery; Protein Structure; Protein-Protein Interactions; Solution Nmr
Molecular mechanisms regulating the form and function of atypical calcium sensor proteins.
Principal investigators: Stathopulos, Peter
Microscale thermophoresis for assessing diverse molecular interactions.
Principal investigators: Stathopulos, Peter
High-throughput Crystallization Imaging System
Principal investigators: Shaw, Gary
Robotic Instrumentation to Establish Workflows for Systematic Cell-Based Analyses.
Principal investigators: Litchfield, David
Operations and Maintenance Support for a Regional Protein Characterization Facility
Principal investigators: Junop, Murray
nNOS regulates store-operated calcium entry in cardiomyocytes
Principal investigators: Feng, Qingping
Keywords: Calcium Handling; Heart Failure; Myocardial Infarction; Nitric Oxide
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Tianqing Peng and Subrata Chakrabarti: 3 shared papers
- Mitsuhiko Ikura and Peter Stathopulos: 1 shared paper
- Tianqing Peng and Peter Stathopulos: 1 shared paper
- Thomas Issekutz and Peter Stathopulos: 1 shared paper
- Subrata Chakrabarti and Peter Stathopulos: 1 shared paper
- Pathology and Laboratory Medicine
- Department of Physiology and Pharmacology
- Research
- Pediatrics
Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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Profile data last refreshed on November 9, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.