Faculty profile
Aleksandar Necakov
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Brock University directory, so their courses may be missing. Find their university profile.
Research
Latest papers
BDNF alters β-cleavage of APP and subcellular distribution of BACE1.
American journal of physiology. Cell physiology · 2026 · senior author
HR3/RORα-mediated cholesterol sensing regulates TOR signaling.
Nature communications · 2026
Notch Signalling Plays a Role in Patterning the Ventral Mesoderm During Early Embryogenesis in Drosophila melanogaster.
International journal of molecular sciences · 2026 · senior author
Latest funding
- $287,000
Optogenetic Control of Notch Signalling in vivo
NSERC · 2018 · Principal investigator
- $12,500
Optogenetic Control of Notch Signalling in vivo
NSERC · 2018 · Principal investigator
16 publications.
BDNF alters β-cleavage of APP and subcellular distribution of BACE1.
Hallam RD, Foran G, Fletcher NK, MacPherson REK, Necakov A
HR3/RORα-mediated cholesterol sensing regulates TOR signaling.
Lassen M, Pardee K, Bradic I, Pedersen LH, Kubrak O, Ahrentløv N, Clancy S, Koyama T, Necakov A, Liu S, Kuksis A, Lajoie G, Edwards A, Teleman AA, Larsen MR, Krause HM, Texada MJ, Rewitz K
Notch Signalling Plays a Role in Patterning the Ventral Mesoderm During Early Embryogenesis in Drosophila melanogaster.
Megaly M, Foran G, Ali A, Turgambayeva A, Sengsouriya T, Berube S, Hallam RD, Liang P, Necakov A
Differences in inflammatory markers, mitochondrial function, and synaptic proteins in male and female Alzheimer's disease post mortem brains.
Yang AJT, Mohammad A, Crozier RWE, Maddalena L, Tsiani E, MacNeil AJ, Spencer GE, Necakov A, Duarte-Guterman P, Stuart J, MacPherson REK
Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping.
Foran G, Hallam RD, Megaly M, Turgambayeva A, Antfolk D, Li Y, Luca VC, Necakov A
Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping.
Foran G, Hallam RD, Megaly M, Turgambayeva A, Antfolk D, Li Y, Luca VC, Necakov A
Human Diseases Associated with Notch Signalling: Lessons from Drosophila melanogaster.
Megaly M, Turgambayeva A, Hallam RD, Foran G, Megaly M, Necakov A
The meaning of ubiquitylation of the DSL ligand Delta for the development of Drosophila.
Troost T, Seib E, Airich A, Vüllings N, Necakov A, De Renzis S, Klein T
Influence of metabolic stress and metformin on synaptic protein profile in SH-SY5Y-derived neurons.
Yang AJT, Mohammad A, Finch MS, Tsiani E, Spencer G, Necakov A, MacPherson REK
PlayBack cloning: simple, reversible, cost-effective cloning for the combinatorial assembly of complex expression constructs.
Foran G, Hallam RD, Megaly M, Turgambayeva A, Necakov A
Optogenetic Control of Notch Signalling in vivo
Principal investigators: Necakov, Aleksandar
Keywords: notch signaling; optogenetics; multicellular development; endogenous gene tagging; live imaging; correlative light-electron microscopy; neuronal differentiation; stem cell signaling and homeostasis; drosophila; human cell culture
Optogenetic Control of Notch Signalling in vivo
Principal investigators: Necakov, Aleksandar
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Evangelia Tsiani and Aleksandar Necakov: 3 shared papers
- Aled Edwards and Keith Pardee: 2 shared papers
- Aleksandar Necakov and Yifeng Li: 2 shared papers
- Aled Edwards and Gilles Lajoie: 1 shared paper
- Aled Edwards and Aleksandar Necakov: 1 shared paper
- Keith Pardee and Gilles Lajoie: 1 shared paper
- Keith Pardee and Aleksandar Necakov: 1 shared paper
- Paula Duarte Guterman and Evangelia Tsiani: 1 shared paper
- Paula Duarte Guterman and Aleksandar Necakov: 1 shared paper
- Ping Liang and Aleksandar Necakov: 1 shared paper
- Ping Liang and Yifeng Li: 1 shared paper
- Travis Dudding and Aleksandar Necakov: 1 shared paper
- Evangelia Tsiani and Gaynor Spencer: 1 shared paper
- Gilles Lajoie and Aleksandar Necakov: 1 shared paper
- Aleksandar Necakov and Gaynor Spencer: 1 shared paper
- Biological Sciences Department
- Health Sciences
- Department of Computer Science
- Terrence Donnelly Centre for Cellular and Biomolecular Research
- Biological Sciences
- Biochemistry
- Biomolecular Sciences
- Other
Co-authors at Brock University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Evangelia Tsiani
Health Sciences
3 shared papers, latest 2025
Yifeng Li
Department of Computer Science
2 shared papers, latest 2024
Gaynor Spencer
Biological Sciences
1 shared papers, latest 2023
Keith Pardee
Biomolecular Sciences
1 shared papers, latest 2026
Paula Duarte Guterman
Psychology
1 shared papers, latest 2025
Aled Edwards
Terrence Donnelly Centre for Cellular and Biomolecular Research
1 shared papers, latest 2026
Travis Dudding
Chemistry
1 shared papers, latest 2020
Gilles Lajoie
Biochemistry
1 shared papers, latest 2026
Ping Liang
Department of Biological Sciences
1 shared papers, latest 2026
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