Faculty profile
Shetuan Zhang
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Research
Latest papers
Amiodarone irrecoverably impairs the function of human ether-a-go-go-related gene potassium channels.
Molecular pharmacology · 2026 · senior author
Effect of oxygen delivery during cardiopulmonary bypass on postoperative neurological outcomes in patients undergoing cardiac surgery: A scoping review of the literature.
Perfusion · 2025
Rescue of expression and function of long QT syndrome-causing mutant hERG channels by enhancing channel stability in the plasma membrane.
The Journal of biological chemistry · 2024 · senior author
Latest funding
- $1,048,050
Molecular mechanisms underlying cardiac surgery associated atrial fibrillation
CIHR · 2022 · Nominated PI
- $125,000
Cardiac-specific Targeting of Tumor Suppressor LATS for Heart Failure Therapy
SSHRC · 2022 · Co-investigator
- $252,000
Identification of the S1-S2 linker as a novel mechanosensor for Kv1.5 regulation
NSERC · 2019 · Principal investigator
41 publications.
Amiodarone irrecoverably impairs the function of human ether-a-go-go-related gene potassium channels.
Gelman I, Li W, Guo J, Bogart-Cherry R, Tomei N, Sharma N, Pan A, Yang T, Baranchuk A, El-Diasty M, Zhang S
Effect of oxygen delivery during cardiopulmonary bypass on postoperative neurological outcomes in patients undergoing cardiac surgery: A scoping review of the literature.
Elsebaie A, Shakeel A, Zhang S, Alarie M, El Tahan M, El-Diasty M
Rescue of expression and function of long QT syndrome-causing mutant hERG channels by enhancing channel stability in the plasma membrane.
Davis J, Cornwell JD, Campagna N, Guo J, Li W, Yang T, Wang T, Zhang S
Ubiquitination is involved in PKC-mediated degradation of cell surface Kv1.5 channels.
Chakraborty A, Paynter A, Szendrey M, Cornwell JD, Li W, Guo J, Yang T, Du Y, Wang T, Zhang S
Opioids-induced inhibition of HERG ion channels and sudden cardiac death, a systematic review of current literature.
El Sherbini A, Liblik K, Lee J, Baranchuk A, Zhang S, El-Diasty M
The ion channel basis of pharmacological effects of amiodarone on myocardial electrophysiological properties, a comprehensive review.
Gelman I, Sharma N, Mckeeman O, Lee P, Campagna N, Tomei N, Baranchuk A, Zhang S, El-Diasty M
Animal models of Lyme carditis. Understanding how to study a complex disease.
Maher S, Scott L, Zhang S, Baranchuk A
The role of pericardial fluid biomarkers in predicting post-operative atrial fibrillation, a comprehensive review of current literature.
Liblik K, Zucker J, Baranchuk A, Fernandez AL, Zhang S, Diasty ME
Differential Effects of Remdesivir and Lumacaftor on Homomeric and Heteromeric hERG Channels.
Campagna N, Wall E, Lee K, Guo J, Li W, Yang T, Baranchuk A, El-Diasty M, Zhang S
Effectiveness of intra-operative topical amiodarone for prevention of postcardiac surgery new-onset atrial fibrillation: A review of current evidence.
Chen X, Sartor C, Zhang S, Baranchuk A, Ross-White A, Fernandez AL, El-Diasty M
Molecular mechanisms underlying cardiac surgery associated atrial fibrillation
Principal investigators: Zhang, Shetuan
Keywords: Animal Model; Atrial Fibrillation; Cardiac Surgery; Cardiomyocytes; Cell Culture; Electrophysiology; Human Samples; Ion Channels; Molecular Biology; Pharmacology
Cardiac-specific Targeting of Tumor Suppressor LATS for Heart Failure Therapy
Principal investigators: Yang, Xiaolong
Keywords: Molecular biology; Cardiovascular pathology; Artificial intelligence; Drug Discovery; Cardiovascular biology; Bioluminescent biosensor; Cardiac-specific targeting; LATS Tumor Suppressor; Nanobubble drug delivery
Identification of the S1-S2 linker as a novel mechanosensor for Kv1.5 regulation
Principal investigators: Zhang, Shetuan
Elucidating the role of S1 and N-terminus in the trafficking and regulation of Kv1.5 potassium channels
Principal investigators: Zhang, Shetuan
Molecular mechanisms of antibody-mediated QT prolongation and cardiac arrhythmias
Principal investigators: Zhang, Shetuan
Keywords: Animal Model; Antibodies; Arrhythmias; Cell Culture; Electrophysiology; Fc Receptor; Herg; Ion Channels; Molecular Biology; Sudden Cardiac Death
Live Cell Imaging Platform for Dynamic Studies of Cellular Interactions
Principal investigators: Zhang, Shetuan
A novel regulation of the hERG channel and its role in long QT syndrome and sudden cardiac death
Principal investigators: Zhang, Shetuan
Keywords: Animal Models; Cardiac Arrhythmias; Cardiac Electrophysiology; Cardiac Ischemia; Herg; Hypokalemia; Ion Channels; Molecular Biology; Patch Clamp; Protease Activities
Regulation of ubiquitin ligase Nedd4-2 and cardiac sodium and potassium ion channels
Principal investigators: Zhang, Shetuan
Pharmacological/nutraceutical rescue of mutated cardiac ion channels to treat inherited cardiac arrhythmias
Principal investigators: Zhang, Shetuan
Keywords: Animal Models And Pharmacology; Drugs And Lipids; Ion Channel Expression; Long Qt Syndrome; Molecular Biology; Patch Clamp; Pharmacology Of Ion Channels; Potassium Channels; Rescue Of Ion Channel Trafficking
Endocytic degradation of hERG potassium channels in cardiac function and disease
Principal investigators: Zhang, Shetuan
Keywords: Cardiac Electrophysiology; Herg; Ion Channel Expression; Ion Channel Trafficking; Long Qt Syndrome; Patch Clamp
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Biomedical and Molecular Sciences
- Pathology and Laboratory Medicine
- Pathology and Molecular Medicine
- Other
Co-authors at Queen's University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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