Faculty profile

Bernard Thébaud

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Full ProfessorPediatricsUniversity of Ottawa

Bernard Thébaud

Full Professor

Pediatrics

Faculty of Medicine

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
9 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 16 research grants (16 CIHR), most recently in 2025.
Supervisor on 7 trainee awards (7 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Ottawa profile.

Newborn Stem Cells Preterm Birth Regenerative Medicine Lung Mesenchymal Stromal Cells Lung Injury Animal Models

Latest papers

Helping Underdeveloped Lungs with Cells (HULC-2): mesenchymal stromal cells in extreme preterm infants at risk of developing bronchopulmonary dysplasia - a study protocol of a phase 2 multicentre double blind randomised controlled trial in Canada.
BMJ open · 2026 · senior author
Improving the precision of AAV lung gene therapy for SP-B deficiency using computationally derived lung-specific promoters.
Gene therapy · 2026
Efficient and safe lung gene delivery using AAV6.2FF in neonatal pigs demonstrates pediatric translational potential.
Molecular therapy. Advances · 2026

All 15 publications

Latest funding

LabPartners-Nexus: Embedding patient engagement in preclinical research across Canada
CIHR · 2026 · Co-investigator
$401,626
Lung specific AAV gene therapy for inherited disorders of surfactant metabolism
CIHR · 2025 · Nominated PI
$1,071,000
Unveiling the potential of next generation cell therapies: induced pluripotent stem cells derived mesenchymal stromal cells for bronchopulmonary dysplasia
CIHR · 2025 · Supervisor
$140,000

All 38 grants and awards

15 publications.

Helping Underdeveloped Lungs with Cells (HULC-2): mesenchymal stromal cells in extreme preterm infants at risk of developing bronchopulmonary dysplasia - a study protocol of a phase 2 multicentre double blind randomised controlled trial in Canada.

Renesme L, Ferretti E, Horth C, Grimwood R, Da Sylva L, Olson V, Cyr-Depauw C, Freund D, Rüdiger M, Möbius MA, Hodgins S, Khan S, Courtman D, Fergusson DA, Thebaud B

BMJ open2026Senior author

DOI: 10.1136/bmjopen-2025-112385 PMID: 42409407

Improving the precision of AAV lung gene therapy for SP-B deficiency using computationally derived lung-specific promoters.

Zielinska N, Howard EL, Stevens BAY, Goens MM, Campbell ESB, Hughes ME, Pei Y, Xu L, Achuthan A, Vadivel A, Apostol A, He X, Zheng D, Gordon DB, Srinivas RR, Nielsen AAK, Caswell JL, Arroyo LG, Yuen DA, Thebaud B, Wootton SK

Gene therapy2026

DOI: 10.1038/s41434-026-00629-x PMID: 42380600

Efficient and safe lung gene delivery using AAV6.2FF in neonatal pigs demonstrates pediatric translational potential.

Zielinska N, Howard EL, Yang C, Stevens BAY, Goens MM, Pei Y, Thompson B, Caswell JL, Thebaud B, Wey D, Valverde A, Arroyo LG, Wootton SK

Molecular therapy. Advances2026

DOI: 10.1016/j.omta.2026.201739 PMID: 42232221

A preclinical systematic review and meta-analysis assessing the effect of biological sex in lipopolysaccharide-induced acute lung injury.

Kuhar E, Chander N, Stewart DJ, Jahandideh F, Zhang H, Kristof AS, Bastarache JA, Schmidt EP, Taljaard M, Thebaud B, Engelberts D, Fergusson DA, Lalu MM

American journal of physiology. Lung cellular and molecular physiology2024

DOI: 10.1152/ajplung.00336.2023 PMID: 38349120

Analysis of the impact of pluronic acid on the thermal stability and infectivity of AAV6.2FF.

Thomas SP, Spinelli MM, Rghei AD, Lopes JA, Zielinska N, McLeod BM, Pei Y, Zhang W, Thebaud B, Karimi K, Wootton SK

BMC biotechnology2024

DOI: 10.1186/s12896-024-00853-6 PMID: 38664752

Effects of prophylactic hydrocortisone in a tertiary Canadian NICU.

de Souza M, Melika R, Thebaud B, Barrowman NJ, Tsampalieros A, Lemyre B

Archives of disease in childhood. Fetal and neonatal edition2024

DOI: 10.1136/archdischild-2023-325913 PMID: 37827815

Advances in neonatal cell therapies: Proceedings of the First Neonatal Cell Therapies Symposium (2022).

Malhotra A, Thebaud B, Paton MCB, Fleiss B, Papagianis P, Baker E, Bennet L, Yawno T, Elwood N, Campbell B, Chand K, Zhou L, Penny T, Nguyen T, Pepe S, Gunn AJ, McDonald CA

Pediatric research2023

DOI: 10.1038/s41390-023-02707-x PMID: 37380752

A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.

Thomas SP, Domm JM, van Vloten JP, Xu L, Vadivel A, Yates JGE, Pei Y, Ingrao J, van Lieshout LP, Jackson SR, Minott JA, Achuthan A, Mehrani Y, McAusland TM, Zhang W, Karimi K, Vaughan AE, de Jong J, Kang MH, Thebaud B, Wootton SK

Molecular therapy : the journal of the American Society of Gene Therapy2023

DOI: 10.1016/j.ymthe.2023.10.002 PMID: 37805711

Landscape analysis for a neonatal disease progression model of bronchopulmonary dysplasia: Leveraging clinical trial experience and real-world data.

Barrett JS, Cala Pane M, Knab T, Roddy W, Beusmans J, Jordie E, Singh K, Davis JM, Romero K, Padula M, Thebaud B, Turner M

Frontiers in pharmacology2022

DOI: 10.3389/fphar.2022.988974 PMID: 36313352

Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians.

McGinn R, Fergusson DA, Stewart DJ, Kristof AS, Barron CC, Thebaud B, McIntyre L, Stacey D, Liepmann M, Dodelet-Devillers A

Critical Care Medicine202110 citations

DOI: 10.1097/ccm.0000000000004734

LabPartners-Nexus: Embedding patient engagement in preclinical research across Canada

Co-investigatorCIHR2026Project Grant

Principal investigators: Lalu, Manoj M; Fergusson, Dean A; Nicholls, Stuart G; Richards, Dawn

Keywords: Knowledge Translation; Patient Engagement; Preclinical Research; Strategy For Patient-Oriented Research

$401,626

Lung specific AAV gene therapy for inherited disorders of surfactant metabolism

Nominated PICIHR2025Project Grant

Principal investigators: Thebaud, Bernard

Keywords: Adeno-Associated Virus (Aav); Gene Therapy; Lung Epithelial Stem/Progenitor Cell; Lung Injury; Lung Regeneration; Surfactant

$1,071,000

Unveiling the potential of next generation cell therapies: induced pluripotent stem cells derived mesenchymal stromal cells for bronchopulmonary dysplasia

SupervisorCIHR2025Canada Postdoctoral Research Award (CPRA) program

Principal investigators: Deguise, Marc-Olivier

Keywords: Bronchopulmonary Dysplasia; Flow Cytometry; Induced Pluripotent Stem Cells; Large Animal Model; Mesenchymal Stromal Cells; Neonatology; Pig; Prematurity; Proteomic; Translation

$140,000

Extracellular vesicles: new biomarkers and therapeutic potential for neonatal lung injury

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Green, Mairead

Keywords: Bronchopulmonary Dysplasia; Extracellular Vesicles; Mesenchymal Stromal Cells

$120,000

LabPartners-Nexus: Embedding patient engagement in preclinical research across Canada's Strategy for Patient-Oriented Research (SPOR) Support units.

Co-investigatorCIHR2025Project Grant - Priority Announcement: Patient-Oriented Research

Principal investigators: Fergusson, Dean A; Lalu, Manoj M; Nicholls, Stuart G; Richards, Dawn

Keywords: Knowledge Translation; Patient Engagement; Preclinical Research; Strategy For Patient-Oriented Research

$100,000

Endothelial colony forming cells dysfunction following preterm birth: Mechanisms and relevance for risk of cardiovascular diseases.

Co-investigatorCIHR2024Project Grant

Principal investigators: Nuyt, Anne Monique; Luu, Thuy Mai

Keywords: Cardiovascular Disease; Endothelial Progenitor Cells; Preterm Birth; Translational Approach

$1,021,276

Therapeutic potential of stem cells in lung injury

Nominated PICIHR2023Project Grant

Principal investigators: Thebaud, Bernard

Keywords: Animal Models; Lung; Mesenchymal Stromal Cells; Newborn; Preterm Birth; Regenerative Medicine; Stem Cells

$971,550

Novel gene therapy platform for monogenetic lung diseases

Nominated PICIHR2023Op. Grant :Bringing Rare Disease Gene Therapies to Clinical Trial Readiness- LOI

Principal investigators: Thebaud, Bernard; Gélinas, Jean-François; Wootton, Sarah

Keywords: Gene Therapy; Respiratory Disease; Surfactant B Deficiency; Viral Vector

Helping Underdeveloped Lungs with Cells (HULC-2) - A Randomized Controlled Trial to test the efficacy of umbilical cord-derived mesenchymal stromal cells (UC-MSC) in reducing respiratory morbidity in preterm infants at risk of bronchopulmonary dysplasia (BPD)

Nominated PICIHR2023Operating Grant: Clinical Trials Projects - Indirect Costs

Principal investigators: Thebaud, Bernard; Robeson, Paula; Fergusson, Dean A

Keywords: Clinical Trial; Lung Injury; Mesenchymal Stromal Cells; Newborn; Outcome; Preterm Birth; Regenerative Medicine; Stem Cells

$575,163

RareKids-CAN: Pediatric Rare Disease Clinical Trials and Treatment Network

Principal investigatorCIHR2023Team Grant: Pediatric Rare Disease Clinical Network

Principal investigators: Lacaze-Masmonteil, Thierry; Anagnostou, Evdokia; Baribeau, Danielle A; Batthish, Michelle; Bernard, Geneviève; Bernier, Francois P; Butcher, Nancy J; Campbell, Craig Gordon N; Cross, Andrea; Dyack, Sarah; Gantt, Soren M; Gravel, Christopher; Haddad, Elie; Heath, Anna; Kelly, Lauren; King, Alexandra; Klassen, Terry P; Knisley, Lisa; Lai, Meng-Chuan; Lewis, Tamorah R; Marwaha, Ashish K; McBride, Kim; Mitchell, John J; Moore Hepburn, Charlotte; Mooser, Vincent E; Myers, Kenneth A; Offringa, Martin; Oskoui, Maryam; Portales-Casamar, Elodie; Pot, Sara; Potter, Elizabeth K; Richer, Lawrence P; Round, Jeff; Stewart, Breanne; Subbarao, Padmaja; Thebaud, Bernard; Turvey, Stuart E; Ward, Leanne M; Wong-Rieger, Durhane; Wright, Nicola A; Yeh, Ann E.

Keywords: Child Health; Data Science; Drug Development; Paediatric Clinical Research Units; Paediatric Clinical Trials; Patient And Public Involvement; Patient Registries; Precision Medicine; Rare Diseases; Real-World Evidence

$19,999,843

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

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Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Newborn Dear Professor Thébaud, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Helping Underdeveloped Lungs with Cells (HULC-2): mesenchymal stromal cells in extreme preterm infants at risk of developing bronchopulmonary dysplasia - a study protocol of a phase 2 multicentre double blind randomised controlled trial in Canada." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Lung specific AAV gene therapy for inherited disorders of surfactant metabolism" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Profile data last refreshed on September 26, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Bernard Thébaud

Research

Latest papers

Latest funding

Helping Underdeveloped Lungs with Cells (HULC-2): mesenchymal stromal cells in extreme preterm infants at risk of developing bronchopulmonary dysplasia - a study protocol of a phase 2 multicentre double blind randomised controlled trial in Canada.

Improving the precision of AAV lung gene therapy for SP-B deficiency using computationally derived lung-specific promoters.

Efficient and safe lung gene delivery using AAV6.2FF in neonatal pigs demonstrates pediatric translational potential.

A preclinical systematic review and meta-analysis assessing the effect of biological sex in lipopolysaccharide-induced acute lung injury.

Analysis of the impact of pluronic acid on the thermal stability and infectivity of AAV6.2FF.

Effects of prophylactic hydrocortisone in a tertiary Canadian NICU.

Advances in neonatal cell therapies: Proceedings of the First Neonatal Cell Therapies Symposium (2022).

A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.

Landscape analysis for a neonatal disease progression model of bronchopulmonary dysplasia: Leveraging clinical trial experience and real-world data.

Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians.

LabPartners-Nexus: Embedding patient engagement in preclinical research across Canada

Lung specific AAV gene therapy for inherited disorders of surfactant metabolism

Unveiling the potential of next generation cell therapies: induced pluripotent stem cells derived mesenchymal stromal cells for bronchopulmonary dysplasia

Extracellular vesicles: new biomarkers and therapeutic potential for neonatal lung injury

LabPartners-Nexus: Embedding patient engagement in preclinical research across Canada's Strategy for Patient-Oriented Research (SPOR) Support units.

Endothelial colony forming cells dysfunction following preterm birth: Mechanisms and relevance for risk of cardiovascular diseases.

Therapeutic potential of stem cells in lung injury

Novel gene therapy platform for monogenetic lung diseases

Helping Underdeveloped Lungs with Cells (HULC-2) - A Randomized Controlled Trial to test the efficacy of umbilical cord-derived mesenchymal stromal cells (UC-MSC) in reducing respiratory morbidity in preterm infants at risk of bronchopulmonary dysplasia (BPD)

RareKids-CAN: Pediatric Rare Disease Clinical Trials and Treatment Network

Frequent collaborators

Haibo Zhang

Wei Zhang

Dawn Stacey

Emanuela Ferretti

Nadia Jahroudi

David Courtman

Ryan McGinn

Judy Illes

Fabio Rossi

Brigitte Lemyre

Alison Fox-Robichaud

Monica Taljaard

Lauralyn McIntyre

Mingyao Liu