Research
Read how they describe their research on their University of Ottawa profile.
Latest papers
Improving the precision of AAV lung gene therapy for SP-B deficiency using computationally derived lung-specific promoters.
Gene therapy · 2026
Helping Underdeveloped Lungs with Cells (HULC-2): mesenchymal stromal cells in extreme preterm infants at risk of developing bronchopulmonary dysplasia - a study protocol of a phase 2 multicentre double blind randomised controlled trial in Canada.
BMJ open · 2026 · senior author
Efficient and safe lung gene delivery using AAV6.2FF in neonatal pigs demonstrates pediatric translational potential.
Molecular therapy. Advances · 2026
Latest funding
- $401,626
LabPartners-Nexus: Embedding patient engagement in preclinical research across Canada
CIHR · 2026 · Co-investigator
- $1,071,000
Lung specific AAV gene therapy for inherited disorders of surfactant metabolism
CIHR · 2025 · Nominated PI
- $140,000
Unveiling the potential of next generation cell therapies: induced pluripotent stem cells derived mesenchymal stromal cells for bronchopulmonary dysplasia
CIHR · 2025 · Supervisor
15 publications.
Improving the precision of AAV lung gene therapy for SP-B deficiency using computationally derived lung-specific promoters.
Zielinska N, Howard EL, Stevens BAY, Goens MM, Campbell ESB, Hughes ME, Pei Y, Xu L, Achuthan A, Vadivel A, Apostol A, He X, Zheng D, Gordon DB, Srinivas RR, Nielsen AAK, Caswell JL, Arroyo LG, Yuen DA, Thebaud B, Wootton SK
Helping Underdeveloped Lungs with Cells (HULC-2): mesenchymal stromal cells in extreme preterm infants at risk of developing bronchopulmonary dysplasia - a study protocol of a phase 2 multicentre double blind randomised controlled trial in Canada.
Renesme L, Ferretti E, Horth C, Grimwood R, Da Sylva L, Olson V, Cyr-Depauw C, Freund D, Rüdiger M, Möbius MA, Hodgins S, Khan S, Courtman D, Fergusson DA, Thebaud B
Efficient and safe lung gene delivery using AAV6.2FF in neonatal pigs demonstrates pediatric translational potential.
Zielinska N, Howard EL, Yang C, Stevens BAY, Goens MM, Pei Y, Thompson B, Caswell JL, Thebaud B, Wey D, Valverde A, Arroyo LG, Wootton SK
A preclinical systematic review and meta-analysis assessing the effect of biological sex in lipopolysaccharide-induced acute lung injury.
Kuhar E, Chander N, Stewart DJ, Jahandideh F, Zhang H, Kristof AS, Bastarache JA, Schmidt EP, Taljaard M, Thebaud B, Engelberts D, Fergusson DA, Lalu MM
Analysis of the impact of pluronic acid on the thermal stability and infectivity of AAV6.2FF.
Thomas SP, Spinelli MM, Rghei AD, Lopes JA, Zielinska N, McLeod BM, Pei Y, Zhang W, Thebaud B, Karimi K, Wootton SK
Effects of prophylactic hydrocortisone in a tertiary Canadian NICU.
de Souza M, Melika R, Thebaud B, Barrowman NJ, Tsampalieros A, Lemyre B
A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.
Thomas SP, Domm JM, van Vloten JP, Xu L, Vadivel A, Yates JGE, Pei Y, Ingrao J, van Lieshout LP, Jackson SR, Minott JA, Achuthan A, Mehrani Y, McAusland TM, Zhang W, Karimi K, Vaughan AE, de Jong J, Kang MH, Thebaud B, Wootton SK
Advances in neonatal cell therapies: Proceedings of the First Neonatal Cell Therapies Symposium (2022).
Malhotra A, Thebaud B, Paton MCB, Fleiss B, Papagianis P, Baker E, Bennet L, Yawno T, Elwood N, Campbell B, Chand K, Zhou L, Penny T, Nguyen T, Pepe S, Gunn AJ, McDonald CA
Landscape analysis for a neonatal disease progression model of bronchopulmonary dysplasia: Leveraging clinical trial experience and real-world data.
Barrett JS, Cala Pane M, Knab T, Roddy W, Beusmans J, Jordie E, Singh K, Davis JM, Romero K, Padula M, Thebaud B, Turner M
Establishment of a consensus definition for mesenchymal stromal cells (MSC) and reporting guidelines for clinical trials of MSC therapy: a modified Delphi study protocol.
Renesme L, Cobey KD, Le M, Lalu MM, Thebaud B
LabPartners-Nexus: Embedding patient engagement in preclinical research across Canada
Principal investigators: Lalu, Manoj M; Fergusson, Dean A; Nicholls, Stuart G; Richards, Dawn
Keywords: Knowledge Translation; Patient Engagement; Preclinical Research; Strategy For Patient-Oriented Research
Lung specific AAV gene therapy for inherited disorders of surfactant metabolism
Principal investigators: Thebaud, Bernard
Keywords: Adeno-Associated Virus (Aav); Gene Therapy; Lung Epithelial Stem/Progenitor Cell; Lung Injury; Lung Regeneration; Surfactant
Unveiling the potential of next generation cell therapies: induced pluripotent stem cells derived mesenchymal stromal cells for bronchopulmonary dysplasia
Principal investigators: Deguise, Marc-Olivier
Keywords: Bronchopulmonary Dysplasia; Flow Cytometry; Induced Pluripotent Stem Cells; Large Animal Model; Mesenchymal Stromal Cells; Neonatology; Pig; Prematurity; Proteomic; Translation
Extracellular vesicles: new biomarkers and therapeutic potential for neonatal lung injury
Principal investigators: Green, Mairead
Keywords: Bronchopulmonary Dysplasia; Extracellular Vesicles; Mesenchymal Stromal Cells
LabPartners-Nexus: Embedding patient engagement in preclinical research across Canada's Strategy for Patient-Oriented Research (SPOR) Support units.
Principal investigators: Fergusson, Dean A; Lalu, Manoj M; Nicholls, Stuart G; Richards, Dawn
Keywords: Knowledge Translation; Patient Engagement; Preclinical Research; Strategy For Patient-Oriented Research
Therapeutic potential of stem cells in lung injury
Principal investigators: Thebaud, Bernard
Keywords: Animal Models; Lung; Mesenchymal Stromal Cells; Newborn; Preterm Birth; Regenerative Medicine; Stem Cells
Novel gene therapy platform for monogenetic lung diseases
Principal investigators: Thebaud, Bernard; Gélinas, Jean-François; Wootton, Sarah
Keywords: Gene Therapy; Respiratory Disease; Surfactant B Deficiency; Viral Vector
Helping Underdeveloped Lungs with Cells (HULC-2) - A Randomized Controlled Trial to test the efficacy of umbilical cord-derived mesenchymal stromal cells (UC-MSC) in reducing respiratory morbidity in preterm infants at risk of bronchopulmonary dysplasia (BPD)
Principal investigators: Thebaud, Bernard; Robeson, Paula; Fergusson, Dean A
Keywords: Clinical Trial; Lung Injury; Mesenchymal Stromal Cells; Newborn; Outcome; Preterm Birth; Regenerative Medicine; Stem Cells
Canada Research Chair - Tier 1
Principal investigators: Thebaud, Bernard
Keywords: Crc
Helping Underdeveloped Lungs with Cells (HULC-2) - A Randomized Controlled Trial to test the efficacy of umbilical cord-derived mesenchymal stromal cells (UC-MSC) in reducing respiratory morbidity in preterm infants at risk of bronchopulmonary dysplasia (BPD)
Principal investigators: Thebaud, Bernard; Robeson, Paula; Fergusson, Dean A
Keywords: Clinical Trial; Lung Injury; Mesenchymal Stromal Cells; Newborn; Outcome; Preterm Birth; Regenerative Medicine; Stem Cells
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Pediatrics
- Anesthesia
- Molecular and Cellular Biology
- Medicine
- Nursing Sciences
- Biomedical Engineering
- Medicine/Neurology
- Other
Co-authors at University of Ottawa, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Wei Zhang
Molecular and Cellular Biology
2 shared papers, latest 2024
Haibo Zhang
Anesthesia
2 shared papers, latest 2024
Fabio Rossi
Biomedical Engineering
1 shared papers, latest 2020
David Courtman
Faculty
1 shared papers, latest 2026
Ryan McGinn
Faculty
1 shared papers, latest 2021
Brigitte Lemyre
Pediatrics
1 shared papers, latest 2024
Judy Illes
Medicine/Neurology
1 shared papers, latest 2020
Emanuela Ferretti
Pediatrics
1 shared papers, latest 2026
Dawn Stacey
Nursing Sciences
1 shared papers, latest 2021
Alison Fox-Robichaud
Medicine
1 shared papers, latest 2021
Monica Taljaard
School of Epidemiology and Public Health
1 shared papers, latest 2024
Lauralyn McIntyre
Clinical Epidemiology
1 shared papers, latest 2021
Mingyao Liu
Department of Surgery
1 shared papers, latest 2021
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.
Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.