Michael De Lisio, University of Ottawa

Research

Inflammation Muscle Stem Cells Cancer Cachexia Artificial Sweeteners Atherosclerosis Cardiovascular Epigenetics Fibro/Adipogenic Precursors

Latest papers

Full-fat dairy milk vs. isolated free nutrient blend on postprandial protein metabolism and inflammatory markers in adults with overweight and obesity.
Clinical nutrition ESPEN · 2026
The LC-NE System as a Candidate Mechanism Linking the Acute Benefits of Exercise on Cognitive and Brain Function in Children.
Medicine and science in sports and exercise · 2026
Relationship between myeloid skewing and colorectal cancer risk in the Framingham Heart Study.
Frontiers in oncology · 2026 · senior author

All 45 publications

Latest funding

SWEETN-CVD: Artificial SWEEteners as New risk factor for CardioVascular Disease
CIHR · 2026 · Principal investigator
$10,000
Poly-ADP-ribosylation signalling in muscle health: A novel determinant of muscle maintenance and function in cancer cachexia
CIHR · 2024 · Principal investigator
$937,125
Uncovering the role of fibro/adipogenic progenitors in the development of stem cell defects and muscle wasting in cancer cachexia.
CIHR · 2024 · Principal investigator
$860,626

All 6 grants and awards

45 publications.

01

Full-fat dairy milk vs. isolated free nutrient blend on postprandial protein metabolism and inflammatory markers in adults with overweight and obesity.

Barnes TM, Zupančič Ž, Deutz MT, Askow AT, McKenna CF, Aguilera JA, Tinline-Goodfellow CT, Ulanov AV, Willard JW, West DWD, De Lisio M, Moore DR, Burd NA

Clinical nutrition ESPEN2026

DOI: 10.1016/j.clnesp.2026.103358 PMID: 42203109

02

The LC-NE System as a Candidate Mechanism Linking the Acute Benefits of Exercise on Cognitive and Brain Function in Children.

Bertrand CM, Raine LB, Luo Y, Shigeta TT, Lloyd KM, Watrous JNH, Hill A, Collao N, Beaudry K, Hsieh SS, Kramer AF, Mullen SP, De Lisio M, Hillman CH

Medicine and science in sports and exercise2026

DOI: 10.1249/mss.0000000000004132 PMID: 42704776

03

Relationship between myeloid skewing and colorectal cancer risk in the Framingham Heart Study.

Ek Orloff L, De Lisio M

Frontiers in oncology2026Senior author

DOI: 10.3389/fonc.2026.1773537 PMID: 42100425

04

Single-Cell RNA-Sequencing Reveals Cachectic Satellite Cell Population in Muscle of Male Mice With Cancer Cachexia.

Brown A, Collao N, Saleh A, Strong N, De Lisio M, Wiper-Bergeron N

Journal of cachexia, sarcopenia and muscle2026

DOI: 10.1002/jcsm.70260 PMID: 41902414

05

Single-cell transcriptomic analysis reveals alterations to cellular dynamics and paracrine signaling in radiation-induced muscle pathology.

Collao N, Johannsen EB, Just J, De Lisio M

American journal of physiology. Cell physiology2025Senior author

DOI: 10.1152/ajpcell.00115.2025 PMID: 40316295

06

High-fat diets promote hematopoietic stem cell expansion and exercise reduces myeloid skewing during maintenance hematopoiesis.

Vanhie JJ, Kim W, Goode C, Collao N, Tate A, De Lisio M

Journal of applied physiology (Bethesda, Md. : 1985)2025Senior author

DOI: 10.1152/japplphysiol.00899.2024 PMID: 40298185

07

Obesity Promotes Marrow-Derived Myeloid Cell Accumulation While Exercise Reduces Proliferative Signaling in Colon Cancer.

Vanhie JJ, Orloff LE, Tate A, Goode C, Collao N, Pisanko A, Power KA, DE Lisio M

Medicine and science in sports and exercise2025Senior author

DOI: 10.1249/mss.0000000000003572 PMID: 39350427

08

The Benefits of Acute Exercise for Children's Cognition Are Associated with Trait Anxiety.

Ligeza TS, Raine LB, Watrous JNH, McDonald KM, DE Lisio M, Mullen SP, Kramer AF, Hillman CH

Medicine and science in sports and exercise2024

DOI: 10.1249/mss.0000000000003492 PMID: 38778470

09

Sex-Based Differences in Muscle Stem Cell Regulation Following Exercise.

Beaudry K, De Lisio M

Exercise and sport sciences reviews2024Senior author

DOI: 10.1249/jes.0000000000000337 PMID: 38445901

10

Radiation induces long-term muscle fibrosis and promotes a fibrotic phenotype in fibro-adipogenic progenitors.

Collao N, D'Souza D, Messeiller L, Pilon E, Lloyd J, Larkin J, Ngu M, Cuillerier A, Green AE, Menzies KJ, Burelle Y, De Lisio M

Journal of cachexia, sarcopenia and muscle2023Senior author

DOI: 10.1002/jcsm.13320 PMID: 37671686

SWEETN-CVD: Artificial SWEEteners as New risk factor for CardioVascular Disease

Principal investigatorCIHR2026TG: Health Effects of Ultra-Proc.Foods-Development of Cardiovascular DiseasesLOI

Principal investigators: Rayner, Katey; De Lisio, Michael

Keywords: Artificial Sweeteners; Atherosclerosis; Cardiovascular; Epigenetics; Inflammation

$10,000

Poly-ADP-ribosylation signalling in muscle health: A novel determinant of muscle maintenance and function in cancer cachexia

Principal investigatorCIHR2024Project Grant

Principal investigators: Menzies, Keir; De Lisio, Michael

Keywords: Cancer Cachexia; Muscle Regeneration; Muscle Wasting; Nad+-Metabolism; Parg; Parp1/Parp2; Poly-Adp-Ribosylation

$937,125

Uncovering the role of fibro/adipogenic progenitors in the development of stem cell defects and muscle wasting in cancer cachexia.

Principal investigatorCIHR2024Project Grant

Principal investigators: Wiper-Bergeron, Nadine L; De Lisio, Michael

Keywords: Cancer Cachexia; Fibro/Adipogenic Precursors; Inflammation; Muscle Atrophy; Muscle Microenvironment; Muscle Stem Cells; Secretome; Single Cell Rna-Seq

$860,626

Understanding the role of fibro/adipogenic progenitors in skeletal muscle hypertrophy

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: De Lisio, Michael

Keywords: exercise; secretome; single cell rna-sequencing; bioinformatics; animal models

$54,000

The role and therapeutic potential of fibro/adipogenic progenitors for cancer therapy-induced muscle pathology

Nominated PICIHR2022Project Grant - Priority Announcement: Pediatric Cancer Research

Principal investigators: De Lisio, Michael

Keywords: Fibrosis; Muscle Stem Cells; Radiation; Rhabdomyosarcoma

$280,500

Mechanisms responsible for exercise-induced alterations in hematopoiesis

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: DeLisio, Michael

$210,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Kinesiology
Cellular and Molecular Medicine
Pathology & Molecular Medicine
Other

Co-authors at University of Ottawa, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Nadine Wiper Bergeron

Cellular and Molecular Medicine

2 shared papers, latest 2026

Jackek Michael Kwiecien

Pathology & Molecular Medicine

1 shared papers, latest 2021

Yan Burelle

Faculty

1 shared papers, latest 2023

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2026

Subject: Prospective PhD student: Inflammation Dear Professor De Lisio, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Full-fat dairy milk vs. isolated free nutrient blend on postprandial protein metabolism and inflammatory markers in adults with overweight and obesity." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "SWEETN-CVD: Artificial SWEEteners as New risk factor for CardioVascular Disease" (2026), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Michael De Lisio